Aptx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Aptx
Entrez Gene ID	259271
Full Name	aprataxin
General protein information	Preferred Names aprataxin Names aprataxin FHA-HIT forkhead-associated domain histidine triad-like protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q22
Summary	human homolog may play a role in DNA repair [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017593171.1	XP_017448660.1	aprataxin isoform X1
XM_006238029.3	XP_006238091.1	aprataxin isoform X3
NM_148889.2	NP_683687.1	aprataxin
XM_006238027.3	XP_006238089.1	aprataxin isoform X2
XM_006238028.3	XP_006238090.1	aprataxin isoform X2
XM_008763607.2	XP_008761829.1	aprataxin isoform X3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Aptx	NP_079821.3
Homo sapiens (human)	APTX	NP_001182177.1
Pan troglodytes (chimpanzee)	APTX	XP_001158355.1
Bos taurus (cattle)	APTX	NP_872595.1
Rattus norvegicus (Norway rat)	Aptx	NP_683687.1
Xenopus tropicalis (tropical clawed frog)	aptx	NP_991394.1
Canis lupus familiaris (dog)	APTX	NP_001003355.1
Danio rerio (zebrafish)	aptx	NP_999894.1
	APTX	XP_002800109.1
Gallus gallus (chicken)	APTX	XP_004949669.1

Gene Ontology
Bibliography

Related articles in PubMed

Ataxia with oculomotor apraxia type1 (AOA1): novel and recurrent aprataxin mutations, coenzyme Q10 analyses, and clinical findings in Italian patients.
Castellotti B, Mariotti C, Rimoldi M, Fancellu R, Plumari M, Caimi S, Uziel G, Nardocci N, Moroni I, Zorzi G, Pareyson D, Di Bella D, Di Donato S, Taroni F, Gellera C
Neurogenetics12(3)193-201(2011 Aug)

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Becherel OJ, Jakob B, Cherry AL, Gueven N, Fusser M, Kijas AW, Peng C, Katyal S, McKinnon PJ, Chen J, Epe B, Smerdon SJ, Taucher-Scholz G, Lavin MF
Nucleic acids research38(5)1489-503(2010 Mar)

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Lieber MR
Annual review of biochemistry79181-211(2010)

A novel mutation of aprataxin associated with ataxia ocular apraxia type 1: phenotypical and genotypical characterization.
Ferrarini M, Squintani G, Cavallaro T, Ferrari S, Rizzuto N, Fabrizi GM
Journal of the neurological sciences260(1-2)219-24(2007 Sep)

Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends.
Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M, Onodera O
Nucleic acids research35(11)3797-809(2007)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Aptx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aptx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02892	NM_148889.2 Latest version!	Rattus norvegicus aprataxin (Aptx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa02892	XM_006238027.3 Latest version!	Rattus norvegicus aprataxin (Aptx), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa02892	XM_006238028.3 Latest version!	Rattus norvegicus aprataxin (Aptx), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa28120	XM_008763607.2 Latest version!	Rattus norvegicus aprataxin (Aptx), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa28120	XM_006238029.3 Latest version!	Rattus norvegicus aprataxin (Aptx), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa28119	XM_017593171.1 Latest version!	Rattus norvegicus aprataxin (Aptx), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aptx ( NM_148889.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_683687.1 Rattus norvegicus aprataxin (Aptx), mRNA.

Price & Availability↑

CloneID	ORa02892
Clone ID Related Accession (Same CDS sequence)	NM_148889.2 , XM_006238027.3 , XM_006238028.3
Accession Version	NM_148889.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078716.1. On Aug 8, 2004 this sequence version replaced NM_148889.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078716.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683687.1
CDS	336..1325
Translation	MRVCWLVRQDCWHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	NM_148889.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148889.2

ORF Insert Sequence:

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aptx ( XM_006238027.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238089.1 Rattus norvegicus aprataxin (Aptx), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa02892
Clone ID Related Accession (Same CDS sequence)	NM_148889.2 , XM_006238027.3 , XM_006238028.3
Accession Version	XM_006238027.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238027.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238089.1
CDS	766..1755
Translation	MRVCWLVRQDCWHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	XM_006238027.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238027.3

ORF Insert Sequence:

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aptx ( XM_006238028.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238090.1 Rattus norvegicus aprataxin (Aptx), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa02892
Clone ID Related Accession (Same CDS sequence)	NM_148889.2 , XM_006238027.3 , XM_006238028.3
Accession Version	XM_006238028.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238028.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238090.1
CDS	614..1603
Translation	MRVCWLVRQDCWHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	XM_006238028.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238028.3

ORF Insert Sequence:

ATGCGGGTGT GCTGGTTGGT GAGACAGGAC TGCTGGCACC AGCGAATCAA ACTTCCCCAT 
TTAGAAGCTG TTGTGATTGG TCGAAGCCCG GAGACCAAGA TCACAGATAA GAAATGTTCC 
CGACAGCAAG TACAGTTGAA AGCGGAGTGT AACAAGAGAT ATGTCAACGT TAAGCAGATG 
GGGGTCAATC CCACCAGCAT TGACGAAGTC GTCATTGGGA AGGACCGGGA GATGAAGCTG 
CTGCCTGGTC AGGTTCTCCA CATGGTGAAT GAACTTTATC CATACATGGT GGAGTTTGAG 
GAGGTGGCAG AGAGCCCTAA CGTAACACAG AGGAAGAGAA AGAGGCCAGA CTGTGATAGT 
CAGGAGATGG AAGCTGAGGC TGGGGCCAGC CCCAGCCAGT GCTCTGTGTC CCCTAAGACG 
GGCAAGCATG GAGCCGCCAA GGAGGAATCA CTGGGCCACT GGAGTCAAGG CTTGAAGATA 
TCTATGAAAG ACCCCAAAAT GCAGGTTTAT AAGGATGATC AGGTGGTGGT GATTAAGGAT 
AAATACCCCA AGGCCCGGCA CCACTGGCTG GTCTTACCAT GGGCCTCCAT TTCCAGTCTG 
AAGGTTGTGA CCAGTGAACA CCTCGAACTT CTCAAACACA TGCACGCAGT AGGGGAAAAG 
GTGATAGCAG ATTTTACTGG ATCCAGCAAA CTGCGCTTCC GACTGGGTTA CCATGCCATT 
CCCAGCATGA GCCATGTACA TCTTCATGTG ATCAGCCAGG ATTTTGATTC TCCTTGCCTT 
AAAAACAAAA AGCATTGGAA TTCTTTCAAT ACAGAATATT TTCTGGAGTC ACAAGCTGTG 
ATCAAGATGG TTCAGGAAGC TGGCAGAGTG ACTGTTAAAG ATGGGACTTG CGAACTCTTG 
AAGCTGCCTC TCCGTTGCCA TGAGTGTCAG CAGCTGCTGC CTTCCATCCC ACAGCTGAAG 
GAGCACCTCA GGAAGCACTG GGGCGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aptx ( XM_006238029.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238091.1 Rattus norvegicus aprataxin (Aptx), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa28120
Clone ID Related Accession (Same CDS sequence)	XM_006238029.3 , XM_008763607.2
Accession Version	XM_006238029.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238029.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGTCA ATCCCACCAG CATTGACGAA GTCGTCATTG GGAAGGACCG GGAGATGAAG 
CTGCTGCCTG GTCAGGTTCT CCACATGGTG AATGAACTTT ATCCATACAT GGTGGAGTTT 
GAGGAGGTGG CAGAGAGCCC TAACGTAACA CAGAGGAAGA GAAAGAGGCC AGACTGTGAT 
AGTCAGGAGA TGGAAGCTGA GGCTGGGGCC AGCCCCAGCC AGTGCTCTGT GTCCCCTAAG 
ACGGGCAAGC ATGGAGCCGC CAAGGAGGAA TCACTGGGCC ACTGGAGTCA AGGCTTGAAG 
ATATCTATGA AAGACCCCAA AATGCAGGTT TATAAGGATG ATCAGGTGGT GGTGATTAAG 
GATAAATACC CCAAGGCCCG GCACCACTGG CTGGTCTTAC CATGGGCCTC CATTTCCAGT 
CTGAAGGTTG TGACCAGTGA ACACCTCGAA CTTCTCAAAC ACATGCACGC AGTAGGGGAA 
AAGGTGATAG CAGATTTTAC TGGATCCAGC AAACTGCGCT TCCGACTGGG TTACCATGCC 
ATTCCCAGCA TGAGCCATGT ACATCTTCAT GTGATCAGCC AGGATTTTGA TTCTCCTTGC 
CTTAAAAACA AAAAGCATTG GAATTCTTTC AATACAGAAT ATTTTCTGGA GTCACAAGCT 
GTGATCAAGA TGGTTCAGGA AGCTGGCAGA GTGACTGTTA AAGATGGGAC TTGCGAACTC 
TTGAAGCTGC CTCTCCGTTG CCATGAGTGT CAGCAGCTGC TGCCTTCCAT CCCACAGCTG 
AAGGAGCACC TCAGGAAGCA CTGGGGCGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238091.1
CDS	133..945
Translation	MGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	XM_006238029.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238029.3

ORF Insert Sequence:

ATGGGGGTCA ATCCCACCAG CATTGACGAA GTCGTCATTG GGAAGGACCG GGAGATGAAG 
CTGCTGCCTG GTCAGGTTCT CCACATGGTG AATGAACTTT ATCCATACAT GGTGGAGTTT 
GAGGAGGTGG CAGAGAGCCC TAACGTAACA CAGAGGAAGA GAAAGAGGCC AGACTGTGAT 
AGTCAGGAGA TGGAAGCTGA GGCTGGGGCC AGCCCCAGCC AGTGCTCTGT GTCCCCTAAG 
ACGGGCAAGC ATGGAGCCGC CAAGGAGGAA TCACTGGGCC ACTGGAGTCA AGGCTTGAAG 
ATATCTATGA AAGACCCCAA AATGCAGGTT TATAAGGATG ATCAGGTGGT GGTGATTAAG 
GATAAATACC CCAAGGCCCG GCACCACTGG CTGGTCTTAC CATGGGCCTC CATTTCCAGT 
CTGAAGGTTG TGACCAGTGA ACACCTCGAA CTTCTCAAAC ACATGCACGC AGTAGGGGAA 
AAGGTGATAG CAGATTTTAC TGGATCCAGC AAACTGCGCT TCCGACTGGG TTACCATGCC 
ATTCCCAGCA TGAGCCATGT ACATCTTCAT GTGATCAGCC AGGATTTTGA TTCTCCTTGC 
CTTAAAAACA AAAAGCATTG GAATTCTTTC AATACAGAAT ATTTTCTGGA GTCACAAGCT 
GTGATCAAGA TGGTTCAGGA AGCTGGCAGA GTGACTGTTA AAGATGGGAC TTGCGAACTC 
TTGAAGCTGC CTCTCCGTTG CCATGAGTGT CAGCAGCTGC TGCCTTCCAT CCCACAGCTG 
AAGGAGCACC TCAGGAAGCA CTGGGGCGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aptx ( XM_008763607.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761829.1 Rattus norvegicus aprataxin (Aptx), transcript variant X5, mRNA.

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CloneID	ORa28120
Clone ID Related Accession (Same CDS sequence)	XM_006238029.3 , XM_008763607.2
Accession Version	XM_008763607.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763607.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGTCA ATCCCACCAG CATTGACGAA GTCGTCATTG GGAAGGACCG GGAGATGAAG 
CTGCTGCCTG GTCAGGTTCT CCACATGGTG AATGAACTTT ATCCATACAT GGTGGAGTTT 
GAGGAGGTGG CAGAGAGCCC TAACGTAACA CAGAGGAAGA GAAAGAGGCC AGACTGTGAT 
AGTCAGGAGA TGGAAGCTGA GGCTGGGGCC AGCCCCAGCC AGTGCTCTGT GTCCCCTAAG 
ACGGGCAAGC ATGGAGCCGC CAAGGAGGAA TCACTGGGCC ACTGGAGTCA AGGCTTGAAG 
ATATCTATGA AAGACCCCAA AATGCAGGTT TATAAGGATG ATCAGGTGGT GGTGATTAAG 
GATAAATACC CCAAGGCCCG GCACCACTGG CTGGTCTTAC CATGGGCCTC CATTTCCAGT 
CTGAAGGTTG TGACCAGTGA ACACCTCGAA CTTCTCAAAC ACATGCACGC AGTAGGGGAA 
AAGGTGATAG CAGATTTTAC TGGATCCAGC AAACTGCGCT TCCGACTGGG TTACCATGCC 
ATTCCCAGCA TGAGCCATGT ACATCTTCAT GTGATCAGCC AGGATTTTGA TTCTCCTTGC 
CTTAAAAACA AAAAGCATTG GAATTCTTTC AATACAGAAT ATTTTCTGGA GTCACAAGCT 
GTGATCAAGA TGGTTCAGGA AGCTGGCAGA GTGACTGTTA AAGATGGGAC TTGCGAACTC 
TTGAAGCTGC CTCTCCGTTG CCATGAGTGT CAGCAGCTGC TGCCTTCCAT CCCACAGCTG 
AAGGAGCACC TCAGGAAGCA CTGGGGCGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761829.1
CDS	803..1615
Translation	MGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	XM_008763607.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763607.2

ORF Insert Sequence:

ATGGGGGTCA ATCCCACCAG CATTGACGAA GTCGTCATTG GGAAGGACCG GGAGATGAAG 
CTGCTGCCTG GTCAGGTTCT CCACATGGTG AATGAACTTT ATCCATACAT GGTGGAGTTT 
GAGGAGGTGG CAGAGAGCCC TAACGTAACA CAGAGGAAGA GAAAGAGGCC AGACTGTGAT 
AGTCAGGAGA TGGAAGCTGA GGCTGGGGCC AGCCCCAGCC AGTGCTCTGT GTCCCCTAAG 
ACGGGCAAGC ATGGAGCCGC CAAGGAGGAA TCACTGGGCC ACTGGAGTCA AGGCTTGAAG 
ATATCTATGA AAGACCCCAA AATGCAGGTT TATAAGGATG ATCAGGTGGT GGTGATTAAG 
GATAAATACC CCAAGGCCCG GCACCACTGG CTGGTCTTAC CATGGGCCTC CATTTCCAGT 
CTGAAGGTTG TGACCAGTGA ACACCTCGAA CTTCTCAAAC ACATGCACGC AGTAGGGGAA 
AAGGTGATAG CAGATTTTAC TGGATCCAGC AAACTGCGCT TCCGACTGGG TTACCATGCC 
ATTCCCAGCA TGAGCCATGT ACATCTTCAT GTGATCAGCC AGGATTTTGA TTCTCCTTGC 
CTTAAAAACA AAAAGCATTG GAATTCTTTC AATACAGAAT ATTTTCTGGA GTCACAAGCT 
GTGATCAAGA TGGTTCAGGA AGCTGGCAGA GTGACTGTTA AAGATGGGAC TTGCGAACTC 
TTGAAGCTGC CTCTCCGTTG CCATGAGTGT CAGCAGCTGC TGCCTTCCAT CCCACAGCTG 
AAGGAGCACC TCAGGAAGCA CTGGGGCGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aptx ( XM_017593171.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448660.1 Rattus norvegicus aprataxin (Aptx), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa28119
Clone ID Related Accession (Same CDS sequence)	XM_017593171.1
Accession Version	XM_017593171.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1032bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	aprataxin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTTG GGCAGGAGGC AAGATATCCC CCAAGAGCCA AGATGCGGGT GTGCTGGTTG 
GTGAGACAGG ACTGCTGGCA CCAGCGAATC AAACTTCCCC ATTTAGAAGC TGTTGTGATT 
GGTCGAAGCC CGGAGACCAA GATCACAGAT AAGAAATGTT CCCGACAGCA AGTACAGTTG 
AAAGCGGAGT GTAACAAGAG ATATGTCAAC GTTAAGCAGA TGGGGGTCAA TCCCACCAGC 
ATTGACGAAG TCGTCATTGG GAAGGACCGG GAGATGAAGC TGCTGCCTGG TCAGGTTCTC 
CACATGGTGA ATGAACTTTA TCCATACATG GTGGAGTTTG AGGAGGTGGC AGAGAGCCCT 
AACGTAACAC AGAGGAAGAG AAAGAGGCCA GACTGTGATA GTCAGGAGAT GGAAGCTGAG 
GCTGGGGCCA GCCCCAGCCA GTGCTCTGTG TCCCCTAAGA CGGGCAAGCA TGGAGCCGCC 
AAGGAGGAAT CACTGGGCCA CTGGAGTCAA GGCTTGAAGA TATCTATGAA AGACCCCAAA 
ATGCAGGTTT ATAAGGATGA TCAGGTGGTG GTGATTAAGG ATAAATACCC CAAGGCCCGG 
CACCACTGGC TGGTCTTACC ATGGGCCTCC ATTTCCAGTC TGAAGGTTGT GACCAGTGAA 
CACCTCGAAC TTCTCAAACA CATGCACGCA GTAGGGGAAA AGGTGATAGC AGATTTTACT 
GGATCCAGCA AACTGCGCTT CCGACTGGGT TACCATGCCA TTCCCAGCAT GAGCCATGTA 
CATCTTCATG TGATCAGCCA GGATTTTGAT TCTCCTTGCC TTAAAAACAA AAAGCATTGG 
AATTCTTTCA ATACAGAATA TTTTCTGGAG TCACAAGCTG TGATCAAGAT GGTTCAGGAA 
GCTGGCAGAG TGACTGTTAA AGATGGGACT TGCGAACTCT TGAAGCTGCC TCTCCGTTGC 
CATGAGTGTC AGCAGCTGCT GCCTTCCATC CCACAGCTGA AGGAGCACCT CAGGAAGCAC 
TGGGGCGGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448660.1
CDS	82..1113
Translation	MLLGQEARYPPRAKMRVCWLVRQDCWHQRIKLPHLEAVVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNPTSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGASPSQCSVSPKTGKHGAAKEESLGHWSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKMVQEAGRVTVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKHWGG

Target ORF information:

RefSeq Version	XM_017593171.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aprataxin (Aptx), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593171.1

ORF Insert Sequence:

ATGCTGCTTG GGCAGGAGGC AAGATATCCC CCAAGAGCCA AGATGCGGGT GTGCTGGTTG 
GTGAGACAGG ACTGCTGGCA CCAGCGAATC AAACTTCCCC ATTTAGAAGC TGTTGTGATT 
GGTCGAAGCC CGGAGACCAA GATCACAGAT AAGAAATGTT CCCGACAGCA AGTACAGTTG 
AAAGCGGAGT GTAACAAGAG ATATGTCAAC GTTAAGCAGA TGGGGGTCAA TCCCACCAGC 
ATTGACGAAG TCGTCATTGG GAAGGACCGG GAGATGAAGC TGCTGCCTGG TCAGGTTCTC 
CACATGGTGA ATGAACTTTA TCCATACATG GTGGAGTTTG AGGAGGTGGC AGAGAGCCCT 
AACGTAACAC AGAGGAAGAG AAAGAGGCCA GACTGTGATA GTCAGGAGAT GGAAGCTGAG 
GCTGGGGCCA GCCCCAGCCA GTGCTCTGTG TCCCCTAAGA CGGGCAAGCA TGGAGCCGCC 
AAGGAGGAAT CACTGGGCCA CTGGAGTCAA GGCTTGAAGA TATCTATGAA AGACCCCAAA 
ATGCAGGTTT ATAAGGATGA TCAGGTGGTG GTGATTAAGG ATAAATACCC CAAGGCCCGG 
CACCACTGGC TGGTCTTACC ATGGGCCTCC ATTTCCAGTC TGAAGGTTGT GACCAGTGAA 
CACCTCGAAC TTCTCAAACA CATGCACGCA GTAGGGGAAA AGGTGATAGC AGATTTTACT 
GGATCCAGCA AACTGCGCTT CCGACTGGGT TACCATGCCA TTCCCAGCAT GAGCCATGTA 
CATCTTCATG TGATCAGCCA GGATTTTGAT TCTCCTTGCC TTAAAAACAA AAAGCATTGG 
AATTCTTTCA ATACAGAATA TTTTCTGGAG TCACAAGCTG TGATCAAGAT GGTTCAGGAA 
GCTGGCAGAG TGACTGTTAA AGATGGGACT TGCGAACTCT TGAAGCTGCC TCTCCGTTGC 
CATGAGTGTC AGCAGCTGCT GCCTTCCATC CCACAGCTGA AGGAGCACCT CAGGAAGCAC 
TGGGGCGGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ataxia with oculomotor apraxia type1 (AOA1): novel and recurrent aprataxin mutations, coenzyme Q10 analyses, and clinical findings in Italian patients.
Neurogenetics12(3)193-201(2011 Aug)
Castellotti B,Mariotti C,Rimoldi M,Fancellu R,Plumari M,Caimi S,Uziel G,Nardocci N,Moroni I,Zorzi G,Pareyson D,Di Bella D,Di Donato S,Taroni F,Gellera C

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Nucleic acids research38(5)1489-503(2010 Mar)
Becherel OJ,Jakob B,Cherry AL,Gueven N,Fusser M,Kijas AW,Peng C,Katyal S,McKinnon PJ,Chen J,Epe B,Smerdon SJ,Taucher-Scholz G,Lavin MF

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Annual review of biochemistry79181-211(2010)
Lieber MR

A novel mutation of aprataxin associated with ataxia ocular apraxia type 1: phenotypical and genotypical characterization.
Journal of the neurological sciences260(1-2)219-24(2007 Sep)
Ferrarini M,Squintani G,Cavallaro T,Ferrari S,Rizzuto N,Fabrizi GM

Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends.
Nucleic acids research35(11)3797-809(2007)
Takahashi T,Tada M,Igarashi S,Koyama A,Date H,Yokoseki A,Shiga A,Yoshida Y,Tsuji S,Nishizawa M,Onodera O

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Aptx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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