Gnaz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gnaz
Entrez Gene ID	25740
Full Name	G protein subunit alpha z
Synonyms	GXA
General protein information	Preferred Names G protein subunit alpha z Names guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide binding protein alpha g(x) alpha chain guanine nucleotide binding protein (G protein), alpha z polypeptide guanine nucleotide binding protein, alpha z polypeptide guanine nucleotide binding protein, alpha z subunit gz-alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	member of a family of G-protein alpha subunits; may have pertussis toxin-insensitive activity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013189.2	NP_037321.1	guanine nucleotide-binding protein G(z) subunit alpha
XM_017601565.1	XP_017457054.1	guanine nucleotide-binding protein G(z) subunit alpha isoform X1
XM_008772866.2	XP_008771088.1	guanine nucleotide-binding protein G(z) subunit alpha isoform X1
XM_008772867.2	XP_008771089.1	guanine nucleotide-binding protein G(z) subunit alpha isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GNAZ	XP_515016.2
Gallus gallus (chicken)	GNAZ	XP_004934410.1
Xenopus tropicalis (tropical clawed frog)	gnaz	NP_001072589.1
Canis lupus familiaris (dog)	GNAZ	XP_848605.1
Mus musculus (house mouse)	Gnaz	NP_034441.1
Rattus norvegicus (Norway rat)	Gnaz	NP_037321.1
Danio rerio (zebrafish)	gnaz	XP_005155691.1
Homo sapiens (human)	GNAZ	NP_002064.1
	GNAZ	XP_001092181.1

Gene Ontology
Bibliography

Related articles in PubMed

Central G-alpha subunit protein-mediated control of cardiovascular function, urine output, and vasopressin secretion in conscious Sprague-Dawley rats.
Wainford RD, Kurtz K, Kapusta DR
American journal of physiology. Regulatory, integrative and comparative physiology295(2)R535-42(2008 Aug)

Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.
Mannoury la Cour C, El Mestikawy S, Hanoun N, Hamon M, Lanfumey L
Molecular pharmacology70(3)1013-21(2006 Sep)

A role for G(z) in pancreatic islet beta-cell biology.
Kimple ME, Nixon AB, Kelly P, Bailey CL, Young KH, Fields TA, Casey PJ
The Journal of biological chemistry280(36)31708-13(2005 Sep)

Endothelin-induced, long lasting, and Ca2+ influx-independent blockade of intrinsic secretion in pituitary cells by Gz subunits.
Andric SA, Zivadinovic D, Gonzalez-Iglesias AE, Lachowicz A, Tomic M, Stojilkovic SS
The Journal of biological chemistry280(29)26896-903(2005 Jul)

Short-term cocaine treatment causes neuroadaptive changes in Galphaq and Galpha11 proteins in rats undergoing withdrawal.
Carrasco GA, Damjanoska KJ, D'Souza DN, Zhang Y, Garcia F, Battaglia G, Muma NA, Van de Kar LD
The Journal of pharmacology and experimental therapeutics311(1)349-55(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Central Galphaz (inhibitory) and Galphaq (stimulatory) activity differentially modulates AVP release to control the pattern of diuresis to intracerebroventricular nociceptin.
Title: Central G-alpha subunit protein-mediated control of cardiovascular function, urine output, and vasopressin secretion in conscious Sprague-Dawley rats.

An endogenous receptor-mediated signaling process in pancreatic beta-cells is dependent on G alpha(z) function.
Title: A role for G(z) in pancreatic islet beta-cell biology.

endothelin-1 in picomolar concentrations can interrupt prolactin release for several hours downstream of spontaneous and high K+-stimulated voltage-gated Ca2+ influx. This action occurred through the Gz signaling pathway.
Title: Endothelin-induced, long lasting, and Ca2+ influx-independent blockade of intrinsic secretion in pituitary cells by Gz subunits.

The following Gnaz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gnaz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02269	NM_013189.2 Latest version!	Rattus norvegicus G protein subunit alpha z (Gnaz), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa02269	XM_008772867.2 Latest version!	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa02269	XM_017601565.1 Latest version!	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa02269	XM_008772866.2 Latest version!	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gnaz ( NM_013189.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037321.1 Rattus norvegicus G protein subunit alpha z (Gnaz), mRNA.

Price & Availability↑

CloneID	ORa02269
Clone ID Related Accession (Same CDS sequence)	NM_013189.2 , XM_017601565.1 , XM_008772866.2 , XM_008772867.2
Accession Version	NM_013189.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(z) subunit alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J03773.1. On Jun 10, 2007 this sequence version replaced NM_013189.1. ##Evidence-Data-START## Transcript exon combination :: J03773.1, BP486875.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037321.1
CDS	15..1082
Translation	MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

Target ORF information:

RefSeq Version	NM_013189.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit alpha z (Gnaz), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013189.2

ORF Insert Sequence:

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gnaz ( XM_017601565.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457054.1 Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa02269
Clone ID Related Accession (Same CDS sequence)	NM_013189.2 , XM_017601565.1 , XM_008772866.2 , XM_008772867.2
Accession Version	XM_017601565.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(z) subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457054.1
CDS	1347..2414
Translation	MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

Target ORF information:

RefSeq Version	XM_017601565.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601565.1

ORF Insert Sequence:

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gnaz ( XM_008772866.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771088.1 Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02269
Clone ID Related Accession (Same CDS sequence)	NM_013189.2 , XM_017601565.1 , XM_008772866.2 , XM_008772867.2
Accession Version	XM_008772866.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(z) subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772866.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771088.1
CDS	808..1875
Translation	MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

Target ORF information:

RefSeq Version	XM_008772866.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008772866.2

ORF Insert Sequence:

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gnaz ( XM_008772867.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771089.1 Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa02269
Clone ID Related Accession (Same CDS sequence)	NM_013189.2 , XM_017601565.1 , XM_008772866.2 , XM_008772867.2
Accession Version	XM_008772867.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(z) subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772867.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771089.1
CDS	943..2010
Translation	MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

Target ORF information:

RefSeq Version	XM_008772867.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit alpha z (Gnaz), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008772867.2

ORF Insert Sequence:

ATGGGATGTC GGCAAAGCTC AGAGGAAAAA GAGGCAGCGC GGCGGTCGAG GAGAATTGAC 
CGCCACCTGC GCTCGGAGAG CCAGCGGCAG CGCCGTGAGA TCAAACTTCT CCTGCTGGGC 
ACCAGCAACT CGGGCAAGAG CACCATCGTC AAGCAGATGA AAATCATCCA CAGCGGTGGT 
TTCAACCTGG AGGCCTGCAA GGAGTACAAG CCCCTCATCA TCTACAACGC CATCGACTCG 
CTGACCCGCA TCATTCGGGC CCTGGCTGCC CTGAAGATTG ATTTCCACAA CCCTGACCGT 
GCCTACGACG CCGTGCAGCT CTTTGCCCTG ACTGGCCCGG CAGAGAGCAA GGGTGAGATC 
ACGCCCGAGC TGCTGGGTGT CATGCGACGG CTCTGGGCTG ACCCCGGGGC CCAGGCCTGC 
TTCGGCCGCT CCAGCGAGTA CCACCTGGAG GACAACGCCG CTTACTACCT GAATGACCTG 
GAGCGCATCG CGGCGCCCGA CTATATCCCC ACGGTGGAGG ACATCCTGCG CTCTCGGGAC 
ATGACCACGG GCATTGTGGA AAACAAGTTC ACCTTCAAGG AGCTTACCTT CAAGATGGTG 
GATGTGGGAG GGCAGAGGTC AGAGCGCAAA AAATGGATCC ACTGCTTTGA GGGCGTGACG 
GCCATCATCT TCTGTGTGGA GCTCAGTGGC TATGACCTGA AGCTTTATGA GGACAACCAG 
ACGAGCCGAA TGGCGGAGAG CCTGCGTCTT TTTGACTCCA TCTGCAACAA CAACTGGTTC 
ATCAACACCT CCCTCATCCT CTTCCTGAAC AAGAAGGACC TCCTGTCGGA GAAGATTCGG 
CGTATCCCGC TCAGCGTCTG CTTCCCCGAG TACAAGGGTC AGAACACGTA CGAGGAAGCC 
GCGGTCTACA TCCAGCGTCA GTTCGAGGAC CTAAACCGAA ACAAGGAGAC CAAGGAGATC 
TACTCGCACT TTACCTGTGC CACCGACACC AGTAACATCC AGTTTGTCTT CGACGCAGTG 
ACAGATGTCA TCATACAGAA CAATCTCAAG TACATTGGCC TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Central G-alpha subunit protein-mediated control of cardiovascular function, urine output, and vasopressin secretion in conscious Sprague-Dawley rats.
American journal of physiology. Regulatory, integrative and comparative physiology295(2)R535-42(2008 Aug)
Wainford RD,Kurtz K,Kapusta DR

Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.
Molecular pharmacology70(3)1013-21(2006 Sep)
Mannoury la Cour C,El Mestikawy S,Hanoun N,Hamon M,Lanfumey L

A role for G(z) in pancreatic islet beta-cell biology.
The Journal of biological chemistry280(36)31708-13(2005 Sep)
Kimple ME,Nixon AB,Kelly P,Bailey CL,Young KH,Fields TA,Casey PJ

Endothelin-induced, long lasting, and Ca2+ influx-independent blockade of intrinsic secretion in pituitary cells by Gz subunits.
The Journal of biological chemistry280(29)26896-903(2005 Jul)
Andric SA,Zivadinovic D,Gonzalez-Iglesias AE,Lachowicz A,Tomic M,Stojilkovic SS

Short-term cocaine treatment causes neuroadaptive changes in Galphaq and Galpha11 proteins in rats undergoing withdrawal.
The Journal of pharmacology and experimental therapeutics311(1)349-55(2004 Oct)
Carrasco GA,Damjanoska KJ,D'Souza DN,Zhang Y,Garcia F,Battaglia G,Muma NA,Van de Kar LD

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Gnaz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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