Slc11a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc11a2
Entrez Gene ID	25715
Full Name	solute carrier family 11 member 2
Synonyms	Dmt1,Nramp2
General protein information	Preferred Names solute carrier family 11 member 2 Names natural resistance-associated macrophage protein 2 DMT-1 NRAMP 2 Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2) divalent cation transporter 1 divalent metal transporter 1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36
Summary	mediates proton coupled transport of broad range of divalent metal ions; may play a role in intestinal iron absorption [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242310.3	XP_006242372.1	natural resistance-associated macrophage protein 2 isoform X2
XM_006242309.3	XP_006242371.1	natural resistance-associated macrophage protein 2 isoform X1
XM_006242312.3	XP_006242374.1	natural resistance-associated macrophage protein 2 isoform X3
NM_013173.2	NP_037305.2	natural resistance-associated macrophage protein 2
XM_006242311.3	XP_006242373.1	natural resistance-associated macrophage protein 2 isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC11A2	XP_003313747.1
Caenorhabditis elegans (roundworm)	smf-2	NP_509131.2
	SLC11A2	XP_001082702.1
Drosophila melanogaster (fruit fly)	Mvl	NP_996251.2
Canis lupus familiaris (dog)	SLC11A2	XP_005636884.1
Rattus norvegicus (Norway rat)	Slc11a2	NP_037305.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012464	XP_315254.3
Caenorhabditis elegans (roundworm)	smf-1	NP_001024792.2
Arabidopsis thaliana (thale cress)	NRAMP5	NP_193614.1
Xenopus tropicalis (tropical clawed frog)	slc11a2	NP_001116938.1
Bos taurus (cattle)	SLC11A2	NP_001094573.1
Mus musculus (house mouse)	Slc11a2	NP_001139633.1
Danio rerio (zebrafish)	slc11a2	NP_001035460.1
Caenorhabditis elegans (roundworm)	smf-3	NP_500235.4
Oryza sativa (rice)	Os12g0581600	NP_001067135.1
Homo sapiens (human)	SLC11A2	NP_001167596.1

Gene Ontology
Bibliography

Related articles in PubMed

A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese.
Wolff NA, Garrick MD, Zhao L, Garrick LM, Ghio AJ, Th?venod F
Scientific reports8(1)211(2018 Jan)

Altered expression of intestinal duodenal cytochrome b and divalent metal transporter 1 might be associated with cardio-renal anemia syndrome.
Naito Y, Sawada H, Oboshi M, Okuno K, Yasumura S, Okuhara Y, Eguchi A, Nishimura K, Soyama Y, Asakura M, Ishihara M, Tsujino T, Masuyama T
Heart and vessels32(11)1410-1414(2017 Nov)

Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.
Han M, Chang J, Kim J
Journal of neurochemistry138(6)918-28(2016 09)

Regulation of the divalent metal ion transporter via membrane budding.
Mackenzie K, Foot NJ, Anand S, Dalton HE, Chaudhary N, Collins BM, Mathivanan S, Kumar S
Cell discovery216011(2016)

Changes of ferrous iron and its transporters after intracerebral hemorrhage in rats.
Wang G, Shao A, Hu W, Xue F, Zhao H, Jin X, Li G, Sun Z, Wang L
International journal of clinical and experimental pathology8(9)10671-9(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mutations in the divalent metal transporter 1 (DMT1) decrease body iron status and up-regulate copper absorption
Title: Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.

work unveils the role of DMT1 in mediating the neuroregenerative action of iron.
Title: DMT1 iron uptake in the PNS: bridging the gap between injury and regeneration.

DMT1 and FPN1 are positively influenced by ferrous iron status in brain after intracerebral hemorrhage. DMT1 and FPN1 attenuate iron overload after ICH via increasing transmembrane iron export.
Title: Changes of ferrous iron and its transporters after intracerebral hemorrhage in rats.

These results suggest that the genetic ablation of iPLA2b increased iron uptake in the brain through the activation of IRP2 and upregulation of DMT1, which may be associated with mitochondrial dysfunction.
Title: Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1.

DMT1 expression was enhanced in the bone tissue of type 2 diabetic rats, and plays an important role in the pathological process of diabetic osteoporosis.
Title: Regulation of DMT1 on Bone Microstructure in Type 2 Diabetes.

The following Slc11a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc11a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13210	NM_013173.2 Latest version!	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa30719	XM_006242309.3 Latest version!	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa30719	XM_006242310.3 Latest version!	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa30720	XM_006242311.3 Latest version!	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa30720	XM_006242312.3 Latest version!	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc11a2 ( NM_013173.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037305.2 Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), mRNA.

Price & Availability↑

CloneID	ORa13210
Clone ID Related Accession (Same CDS sequence)	NM_013173.2
Accession Version	NM_013173.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1779bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	natural resistance-associated macrophage protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF008439.1. On Aug 3, 2012 this sequence version replaced NM_013173.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF008439.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGGTAAGCAT CTCTAAAGTC 
CTGCTGAGCG AAGATACCAG CGGTGGCAAT ACTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037305.2
CDS	1..1779
Translation	MGKKQPRAAASAAPNCELKSYSKSTDPQVSTMVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSVSISKVLLSEDTSGGNTK

Target ORF information:

RefSeq Version	NM_013173.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013173.2

ORF Insert Sequence:

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGGTAAGCAT CTCTAAAGTC 
CTGCTGAGCG AAGATACCAG CGGTGGCAAT ACTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc11a2 ( XM_006242310.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242372.1 Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa30719
Clone ID Related Accession (Same CDS sequence)	XM_006242310.3 , XM_006242309.3
Accession Version	XM_006242310.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	natural resistance-associated macrophage protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242310.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGTACCACCT CGGACTGACC 
GCTAGGCCTG AACTCTACCT CCTGAACACC GTGGACGCCG TCTCGCTGGT ATCTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242372.1
CDS	23..1822
Translation	MGKKQPRAAASAAPNCELKSYSKSTDPQVSTMVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSYHLGLTARPELYLLNTVDAVSLVSR

Target ORF information:

RefSeq Version	XM_006242310.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242310.3

ORF Insert Sequence:

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGTACCACCT CGGACTGACC 
GCTAGGCCTG AACTCTACCT CCTGAACACC GTGGACGCCG TCTCGCTGGT ATCTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc11a2 ( XM_006242309.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242371.1 Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30719
Clone ID Related Accession (Same CDS sequence)	XM_006242310.3 , XM_006242309.3
Accession Version	XM_006242309.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	natural resistance-associated macrophage protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242309.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGTACCACCT CGGACTGACC 
GCTAGGCCTG AACTCTACCT CCTGAACACC GTGGACGCCG TCTCGCTGGT ATCTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242371.1
CDS	22..1821
Translation	MGKKQPRAAASAAPNCELKSYSKSTDPQVSTMVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSYHLGLTARPELYLLNTVDAVSLVSR

Target ORF information:

RefSeq Version	XM_006242309.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242309.3

ORF Insert Sequence:

ATGGGGAAGA AGCAGCCGAG GGCAGCAGCA AGTGCTGCTC CAAACTGTGA GCTAAAATCC 
TATTCTAAGA GCACAGATCC TCAGGTATCT ACCATGGTGT TGGATCCTGA AGAAAAGATT 
CCAGACGATG GTGCTTCTGG GGACCATGGA GACTCGGCCA GCCTCGGTGC CATCAACCCT 
GCTTACAGCA ACTCTTCCCT CCCACATTCC ACCGGGGATT CTGAGGAGCC CTTCACCACC 
TACTTTGATG AGAAAATCCC CATTCCTGAG GAGGAGTACT CTTGTTTTAG TTTCCGTAAA 
CTCTGGGCCT TCACAGGACC TGGTTTTCTT ATGAGCATTG CCTACCTGGA TCCAGGAAAC 
ATTGAATCTG ATTTACAGTC TGGAGCAGTG GCTGGATTTA AGTTGCTCTG GGTGCTCCTG 
CTGGCCACTA TTGTGGGGCT GCTGCTCCAG CGTCTCGCAG CTCGACTGGG AGTGGTCACC 
GGCTTGCACC TTGCTGAAGT GTGTCACCGT CAGTATCCCA AGGTCCCACG GATCATCCTG 
TGGCTAATGG TGGAGTTGGC AATCATTGGT TCTGATATGC AGGAAGTCAT TGGCTCAGCC 
ATCGCCATCA ATCTCCTGTC TGCCGGAAGG GTTCCCCTGT ATGGTGGAGT CCTCATCACC 
ATCGCAGATA CTTTTGTATT TCTCTTTTTG GACAAATATG GCTTGCGGAA GCTGGAAGCA 
TTTTTTGGCT TTCTCATCAC TATCATGGCC CTCACATTTG GATATGAGTA TGTTACAGTG 
AAACCCAGCC AAAGCCAAGT ACTCAGGGGC ATGTTCGTGC CATCCTGTTC AGGCTGCCAC 
ACCCCTCAGG TGGAGCAGGC GGTGGGCATC GTGGGAGCTG TGATCATGCC ACACAACATG 
TACCTGCACT CTGCCTTAGT CAAGTCTAGA CAAGTGAACC GGGCCAATAA GCAGGAAGTT 
CGAGAAGCCA ATAAGTACTT CTTCATCGAG TCCTGCATTG CACTCTTTGT TTCCTTCATC 
ATCAATGTCT TTGTCGTCTC CGTCTTTGCT GAAGCATTTT TTGAGAAAAC CAATGAGCAG 
GTGGTTGAGG TCTGCAGAAA TAGCAGCAGC CCCCATGCTG ACCTCTTTCC TAACGACAAC 
TCTACCCTGG CTGTGGACAT CTACAAAGGG GGTGTTGTGC TTGGATGTTA CTTCGGGCCT 
GCGGCCCTCT ACATCTGGGC GGTGGGGATC CTGGCTGCTG GACAGAGCTC CACCATGACT 
GGAACCTATT CTGGCCAGTT TGTCATGGAG GGATTCCTGA ACCTAAAATG GTCGCGCTTT 
GCCCGCGTGA TCCTGACCAG GTCTATTGCC ATCATCCCTA CCCTGCTTGT TGCTGTCTTC 
CAAGATGTGG AGCATCTGAC AGGGATGAAT GATTTCCTGA ATGTTCTGCA GAGCCTACAG 
CTCCCCTTTG CCCTCATCCC TATCCTCACC TTCACAAGCC TGCGGCCAGT GATGAGTGAG 
TTCTCCAACG GAATAGGCTG GAGGATCGCA GGCGGCATCT TGGTCCTTCT CGTCTGCTCC 
ATCAACATGT ACTTTGTCGT GGTCTACGTC CAGGAGCTAG GGCATGTGGC ACTGTATGTG 
GTGGCTGCAG TGGTTAGCGT GGCTTATCTG GGCTTTGTGT TCTACTTGGG TTGGCAGTGT 
TTGATTGCGT TGGGCCTGTC GTTCCTGGAC TGTGGGCGCT CGTACCACCT CGGACTGACC 
GCTAGGCCTG AACTCTACCT CCTGAACACC GTGGACGCCG TCTCGCTGGT ATCTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc11a2 ( XM_006242312.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242374.1 Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa30720
Clone ID Related Accession (Same CDS sequence)	XM_006242312.3 , XM_006242311.3
Accession Version	XM_006242312.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	natural resistance-associated macrophage protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242312.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTGG ATCCTGAAGA AAAGATTCCA GACGATGGTG CTTCTGGGGA CCATGGAGAC 
TCGGCCAGCC TCGGTGCCAT CAACCCTGCT TACAGCAACT CTTCCCTCCC ACATTCCACC 
GGGGATTCTG AGGAGCCCTT CACCACCTAC TTTGATGAGA AAATCCCCAT TCCTGAGGAG 
GAGTACTCTT GTTTTAGTTT CCGTAAACTC TGGGCCTTCA CAGGACCTGG TTTTCTTATG 
AGCATTGCCT ACCTGGATCC AGGAAACATT GAATCTGATT TACAGTCTGG AGCAGTGGCT 
GGATTTAAGT TGCTCTGGGT GCTCCTGCTG GCCACTATTG TGGGGCTGCT GCTCCAGCGT 
CTCGCAGCTC GACTGGGAGT GGTCACCGGC TTGCACCTTG CTGAAGTGTG TCACCGTCAG 
TATCCCAAGG TCCCACGGAT CATCCTGTGG CTAATGGTGG AGTTGGCAAT CATTGGTTCT 
GATATGCAGG AAGTCATTGG CTCAGCCATC GCCATCAATC TCCTGTCTGC CGGAAGGGTT 
CCCCTGTATG GTGGAGTCCT CATCACCATC GCAGATACTT TTGTATTTCT CTTTTTGGAC 
AAATATGGCT TGCGGAAGCT GGAAGCATTT TTTGGCTTTC TCATCACTAT CATGGCCCTC 
ACATTTGGAT ATGAGTATGT TACAGTGAAA CCCAGCCAAA GCCAAGTACT CAGGGGCATG 
TTCGTGCCAT CCTGTTCAGG CTGCCACACC CCTCAGGTGG AGCAGGCGGT GGGCATCGTG 
GGAGCTGTGA TCATGCCACA CAACATGTAC CTGCACTCTG CCTTAGTCAA GTCTAGACAA 
GTGAACCGGG CCAATAAGCA GGAAGTTCGA GAAGCCAATA AGTACTTCTT CATCGAGTCC 
TGCATTGCAC TCTTTGTTTC CTTCATCATC AATGTCTTTG TCGTCTCCGT CTTTGCTGAA 
GCATTTTTTG AGAAAACCAA TGAGCAGGTG GTTGAGGTCT GCAGAAATAG CAGCAGCCCC 
CATGCTGACC TCTTTCCTAA CGACAACTCT ACCCTGGCTG TGGACATCTA CAAAGGGGGT 
GTTGTGCTTG GATGTTACTT CGGGCCTGCG GCCCTCTACA TCTGGGCGGT GGGGATCCTG 
GCTGCTGGAC AGAGCTCCAC CATGACTGGA ACCTATTCTG GCCAGTTTGT CATGGAGGGA 
TTCCTGAACC TAAAATGGTC GCGCTTTGCC CGCGTGATCC TGACCAGGTC TATTGCCATC 
ATCCCTACCC TGCTTGTTGC TGTCTTCCAA GATGTGGAGC ATCTGACAGG GATGAATGAT 
TTCCTGAATG TTCTGCAGAG CCTACAGCTC CCCTTTGCCC TCATCCCTAT CCTCACCTTC 
ACAAGCCTGC GGCCAGTGAT GAGTGAGTTC TCCAACGGAA TAGGCTGGAG GATCGCAGGC 
GGCATCTTGG TCCTTCTCGT CTGCTCCATC AACATGTACT TTGTCGTGGT CTACGTCCAG 
GAGCTAGGGC ATGTGGCACT GTATGTGGTG GCTGCAGTGG TTAGCGTGGC TTATCTGGGC 
TTTGTGTTCT ACTTGGGTTG GCAGTGTTTG ATTGCGTTGG GCCTGTCGTT CCTGGACTGT 
GGGCGCTCGT ACCACCTCGG ACTGACCGCT AGGCCTGAAC TCTACCTCCT GAACACCGTG 
GACGCCGTCT CGCTGGTATC TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242374.1
CDS	784..2490
Translation	MVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSYHLGLTARPELYLLNTVDAVSLVSR

Target ORF information:

RefSeq Version	XM_006242312.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242312.3

ORF Insert Sequence:

ATGGTGTTGG ATCCTGAAGA AAAGATTCCA GACGATGGTG CTTCTGGGGA CCATGGAGAC 
TCGGCCAGCC TCGGTGCCAT CAACCCTGCT TACAGCAACT CTTCCCTCCC ACATTCCACC 
GGGGATTCTG AGGAGCCCTT CACCACCTAC TTTGATGAGA AAATCCCCAT TCCTGAGGAG 
GAGTACTCTT GTTTTAGTTT CCGTAAACTC TGGGCCTTCA CAGGACCTGG TTTTCTTATG 
AGCATTGCCT ACCTGGATCC AGGAAACATT GAATCTGATT TACAGTCTGG AGCAGTGGCT 
GGATTTAAGT TGCTCTGGGT GCTCCTGCTG GCCACTATTG TGGGGCTGCT GCTCCAGCGT 
CTCGCAGCTC GACTGGGAGT GGTCACCGGC TTGCACCTTG CTGAAGTGTG TCACCGTCAG 
TATCCCAAGG TCCCACGGAT CATCCTGTGG CTAATGGTGG AGTTGGCAAT CATTGGTTCT 
GATATGCAGG AAGTCATTGG CTCAGCCATC GCCATCAATC TCCTGTCTGC CGGAAGGGTT 
CCCCTGTATG GTGGAGTCCT CATCACCATC GCAGATACTT TTGTATTTCT CTTTTTGGAC 
AAATATGGCT TGCGGAAGCT GGAAGCATTT TTTGGCTTTC TCATCACTAT CATGGCCCTC 
ACATTTGGAT ATGAGTATGT TACAGTGAAA CCCAGCCAAA GCCAAGTACT CAGGGGCATG 
TTCGTGCCAT CCTGTTCAGG CTGCCACACC CCTCAGGTGG AGCAGGCGGT GGGCATCGTG 
GGAGCTGTGA TCATGCCACA CAACATGTAC CTGCACTCTG CCTTAGTCAA GTCTAGACAA 
GTGAACCGGG CCAATAAGCA GGAAGTTCGA GAAGCCAATA AGTACTTCTT CATCGAGTCC 
TGCATTGCAC TCTTTGTTTC CTTCATCATC AATGTCTTTG TCGTCTCCGT CTTTGCTGAA 
GCATTTTTTG AGAAAACCAA TGAGCAGGTG GTTGAGGTCT GCAGAAATAG CAGCAGCCCC 
CATGCTGACC TCTTTCCTAA CGACAACTCT ACCCTGGCTG TGGACATCTA CAAAGGGGGT 
GTTGTGCTTG GATGTTACTT CGGGCCTGCG GCCCTCTACA TCTGGGCGGT GGGGATCCTG 
GCTGCTGGAC AGAGCTCCAC CATGACTGGA ACCTATTCTG GCCAGTTTGT CATGGAGGGA 
TTCCTGAACC TAAAATGGTC GCGCTTTGCC CGCGTGATCC TGACCAGGTC TATTGCCATC 
ATCCCTACCC TGCTTGTTGC TGTCTTCCAA GATGTGGAGC ATCTGACAGG GATGAATGAT 
TTCCTGAATG TTCTGCAGAG CCTACAGCTC CCCTTTGCCC TCATCCCTAT CCTCACCTTC 
ACAAGCCTGC GGCCAGTGAT GAGTGAGTTC TCCAACGGAA TAGGCTGGAG GATCGCAGGC 
GGCATCTTGG TCCTTCTCGT CTGCTCCATC AACATGTACT TTGTCGTGGT CTACGTCCAG 
GAGCTAGGGC ATGTGGCACT GTATGTGGTG GCTGCAGTGG TTAGCGTGGC TTATCTGGGC 
TTTGTGTTCT ACTTGGGTTG GCAGTGTTTG ATTGCGTTGG GCCTGTCGTT CCTGGACTGT 
GGGCGCTCGT ACCACCTCGG ACTGACCGCT AGGCCTGAAC TCTACCTCCT GAACACCGTG 
GACGCCGTCT CGCTGGTATC TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc11a2 ( XM_006242311.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242373.1 Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa30720
Clone ID Related Accession (Same CDS sequence)	XM_006242312.3 , XM_006242311.3
Accession Version	XM_006242311.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	natural resistance-associated macrophage protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242311.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTGG ATCCTGAAGA AAAGATTCCA GACGATGGTG CTTCTGGGGA CCATGGAGAC 
TCGGCCAGCC TCGGTGCCAT CAACCCTGCT TACAGCAACT CTTCCCTCCC ACATTCCACC 
GGGGATTCTG AGGAGCCCTT CACCACCTAC TTTGATGAGA AAATCCCCAT TCCTGAGGAG 
GAGTACTCTT GTTTTAGTTT CCGTAAACTC TGGGCCTTCA CAGGACCTGG TTTTCTTATG 
AGCATTGCCT ACCTGGATCC AGGAAACATT GAATCTGATT TACAGTCTGG AGCAGTGGCT 
GGATTTAAGT TGCTCTGGGT GCTCCTGCTG GCCACTATTG TGGGGCTGCT GCTCCAGCGT 
CTCGCAGCTC GACTGGGAGT GGTCACCGGC TTGCACCTTG CTGAAGTGTG TCACCGTCAG 
TATCCCAAGG TCCCACGGAT CATCCTGTGG CTAATGGTGG AGTTGGCAAT CATTGGTTCT 
GATATGCAGG AAGTCATTGG CTCAGCCATC GCCATCAATC TCCTGTCTGC CGGAAGGGTT 
CCCCTGTATG GTGGAGTCCT CATCACCATC GCAGATACTT TTGTATTTCT CTTTTTGGAC 
AAATATGGCT TGCGGAAGCT GGAAGCATTT TTTGGCTTTC TCATCACTAT CATGGCCCTC 
ACATTTGGAT ATGAGTATGT TACAGTGAAA CCCAGCCAAA GCCAAGTACT CAGGGGCATG 
TTCGTGCCAT CCTGTTCAGG CTGCCACACC CCTCAGGTGG AGCAGGCGGT GGGCATCGTG 
GGAGCTGTGA TCATGCCACA CAACATGTAC CTGCACTCTG CCTTAGTCAA GTCTAGACAA 
GTGAACCGGG CCAATAAGCA GGAAGTTCGA GAAGCCAATA AGTACTTCTT CATCGAGTCC 
TGCATTGCAC TCTTTGTTTC CTTCATCATC AATGTCTTTG TCGTCTCCGT CTTTGCTGAA 
GCATTTTTTG AGAAAACCAA TGAGCAGGTG GTTGAGGTCT GCAGAAATAG CAGCAGCCCC 
CATGCTGACC TCTTTCCTAA CGACAACTCT ACCCTGGCTG TGGACATCTA CAAAGGGGGT 
GTTGTGCTTG GATGTTACTT CGGGCCTGCG GCCCTCTACA TCTGGGCGGT GGGGATCCTG 
GCTGCTGGAC AGAGCTCCAC CATGACTGGA ACCTATTCTG GCCAGTTTGT CATGGAGGGA 
TTCCTGAACC TAAAATGGTC GCGCTTTGCC CGCGTGATCC TGACCAGGTC TATTGCCATC 
ATCCCTACCC TGCTTGTTGC TGTCTTCCAA GATGTGGAGC ATCTGACAGG GATGAATGAT 
TTCCTGAATG TTCTGCAGAG CCTACAGCTC CCCTTTGCCC TCATCCCTAT CCTCACCTTC 
ACAAGCCTGC GGCCAGTGAT GAGTGAGTTC TCCAACGGAA TAGGCTGGAG GATCGCAGGC 
GGCATCTTGG TCCTTCTCGT CTGCTCCATC AACATGTACT TTGTCGTGGT CTACGTCCAG 
GAGCTAGGGC ATGTGGCACT GTATGTGGTG GCTGCAGTGG TTAGCGTGGC TTATCTGGGC 
TTTGTGTTCT ACTTGGGTTG GCAGTGTTTG ATTGCGTTGG GCCTGTCGTT CCTGGACTGT 
GGGCGCTCGT ACCACCTCGG ACTGACCGCT AGGCCTGAAC TCTACCTCCT GAACACCGTG 
GACGCCGTCT CGCTGGTATC TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242373.1
CDS	132..1838
Translation	MVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSYHLGLTARPELYLLNTVDAVSLVSR

Target ORF information:

RefSeq Version	XM_006242311.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 11 member 2 (Slc11a2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242311.3

ORF Insert Sequence:

ATGGTGTTGG ATCCTGAAGA AAAGATTCCA GACGATGGTG CTTCTGGGGA CCATGGAGAC 
TCGGCCAGCC TCGGTGCCAT CAACCCTGCT TACAGCAACT CTTCCCTCCC ACATTCCACC 
GGGGATTCTG AGGAGCCCTT CACCACCTAC TTTGATGAGA AAATCCCCAT TCCTGAGGAG 
GAGTACTCTT GTTTTAGTTT CCGTAAACTC TGGGCCTTCA CAGGACCTGG TTTTCTTATG 
AGCATTGCCT ACCTGGATCC AGGAAACATT GAATCTGATT TACAGTCTGG AGCAGTGGCT 
GGATTTAAGT TGCTCTGGGT GCTCCTGCTG GCCACTATTG TGGGGCTGCT GCTCCAGCGT 
CTCGCAGCTC GACTGGGAGT GGTCACCGGC TTGCACCTTG CTGAAGTGTG TCACCGTCAG 
TATCCCAAGG TCCCACGGAT CATCCTGTGG CTAATGGTGG AGTTGGCAAT CATTGGTTCT 
GATATGCAGG AAGTCATTGG CTCAGCCATC GCCATCAATC TCCTGTCTGC CGGAAGGGTT 
CCCCTGTATG GTGGAGTCCT CATCACCATC GCAGATACTT TTGTATTTCT CTTTTTGGAC 
AAATATGGCT TGCGGAAGCT GGAAGCATTT TTTGGCTTTC TCATCACTAT CATGGCCCTC 
ACATTTGGAT ATGAGTATGT TACAGTGAAA CCCAGCCAAA GCCAAGTACT CAGGGGCATG 
TTCGTGCCAT CCTGTTCAGG CTGCCACACC CCTCAGGTGG AGCAGGCGGT GGGCATCGTG 
GGAGCTGTGA TCATGCCACA CAACATGTAC CTGCACTCTG CCTTAGTCAA GTCTAGACAA 
GTGAACCGGG CCAATAAGCA GGAAGTTCGA GAAGCCAATA AGTACTTCTT CATCGAGTCC 
TGCATTGCAC TCTTTGTTTC CTTCATCATC AATGTCTTTG TCGTCTCCGT CTTTGCTGAA 
GCATTTTTTG AGAAAACCAA TGAGCAGGTG GTTGAGGTCT GCAGAAATAG CAGCAGCCCC 
CATGCTGACC TCTTTCCTAA CGACAACTCT ACCCTGGCTG TGGACATCTA CAAAGGGGGT 
GTTGTGCTTG GATGTTACTT CGGGCCTGCG GCCCTCTACA TCTGGGCGGT GGGGATCCTG 
GCTGCTGGAC AGAGCTCCAC CATGACTGGA ACCTATTCTG GCCAGTTTGT CATGGAGGGA 
TTCCTGAACC TAAAATGGTC GCGCTTTGCC CGCGTGATCC TGACCAGGTC TATTGCCATC 
ATCCCTACCC TGCTTGTTGC TGTCTTCCAA GATGTGGAGC ATCTGACAGG GATGAATGAT 
TTCCTGAATG TTCTGCAGAG CCTACAGCTC CCCTTTGCCC TCATCCCTAT CCTCACCTTC 
ACAAGCCTGC GGCCAGTGAT GAGTGAGTTC TCCAACGGAA TAGGCTGGAG GATCGCAGGC 
GGCATCTTGG TCCTTCTCGT CTGCTCCATC AACATGTACT TTGTCGTGGT CTACGTCCAG 
GAGCTAGGGC ATGTGGCACT GTATGTGGTG GCTGCAGTGG TTAGCGTGGC TTATCTGGGC 
TTTGTGTTCT ACTTGGGTTG GCAGTGTTTG ATTGCGTTGG GCCTGTCGTT CCTGGACTGT 
GGGCGCTCGT ACCACCTCGG ACTGACCGCT AGGCCTGAAC TCTACCTCCT GAACACCGTG 
GACGCCGTCT CGCTGGTATC TAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese.
Scientific reports8(1)211(2018 Jan)
Wolff NA,Garrick MD,Zhao L,Garrick LM,Ghio AJ,Th?venod F

Altered expression of intestinal duodenal cytochrome b and divalent metal transporter 1 might be associated with cardio-renal anemia syndrome.
Heart and vessels32(11)1410-1414(2017 Nov)
Naito Y,Sawada H,Oboshi M,Okuno K,Yasumura S,Okuhara Y,Eguchi A,Nishimura K,Soyama Y,Asakura M,Ishihara M,Tsujino T,Masuyama T

Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.
Journal of neurochemistry138(6)918-28(2016 09)
Han M,Chang J,Kim J

Regulation of the divalent metal ion transporter via membrane budding.
Cell discovery216011(2016)
Mackenzie K,Foot NJ,Anand S,Dalton HE,Chaudhary N,Collins BM,Mathivanan S,Kumar S

Changes of ferrous iron and its transporters after intracerebral hemorrhage in rats.
International journal of clinical and experimental pathology8(9)10671-9(2015)
Wang G,Shao A,Hu W,Xue F,Zhao H,Jin X,Li G,Sun Z,Wang L

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Slc11a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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