Itgb7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itgb7
Entrez Gene ID	25713
Full Name	integrin subunit beta 7
General protein information	Preferred Names integrin subunit beta 7 Names integrin beta-7 integrin, beta 7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36
Summary	mediates adhesion to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013171.1	NP_037303.1	integrin beta-7 precursor
XM_006242383.3	XP_006242445.1	integrin beta-7 isoform X1

Pathways from BioSystems

Homologies

	ITGB7	XP_001087864.2
Canis lupus familiaris (dog)	ITGB7	XP_005637466.1
Xenopus tropicalis (tropical clawed frog)	itgb7	XP_002936686.2
Bos taurus (cattle)	ITGB7	NP_001098835.1
Rattus norvegicus (Norway rat)	Itgb7	NP_037303.1
Homo sapiens (human)	ITGB7	NP_000880.1
Danio rerio (zebrafish)	LOC797491	XP_001337949.3
Pan troglodytes (chimpanzee)	ITGB7	XP_001141622.1
Mus musculus (house mouse)	Itgb7	NP_038594.2

Gene Ontology
Bibliography

Related articles in PubMed

Disruption of disulfide restriction at integrin knees induces activation and ligand-independent signaling of ????.
Zhang K, Pan Y, Qi J, Yue J, Zhang M, Xu C, Li G, Chen J
Journal of cell science126(Pt 21)5030-41(2013 Nov)

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
Kim SV, Xiang WV, Kwak C, Yang Y, Lin XW, Ota M, Sarpel U, Rifkin DB, Xu R, Littman DR
Science (New York, N.Y.)340(6139)1456-9(2013 Jun)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Itgb7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itgb7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02208	NM_013171.1 Latest version!	Rattus norvegicus integrin subunit beta 7 (Itgb7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa02208	XM_006242383.3 Latest version!	Rattus norvegicus integrin subunit beta 7 (Itgb7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itgb7 ( NM_013171.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037303.1 Rattus norvegicus integrin subunit beta 7 (Itgb7), mRNA.

Price & Availability↑

CloneID	ORa02208
Clone ID Related Accession (Same CDS sequence)	NM_013171.1 , XM_006242383.3
Accession Version	NM_013171.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-7 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC110347.6. On or before Dec 13, 2009 this sequence version replaced XM_343336.3, XM_001067562.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGTGGATT CATCAACTGT TCTCATTTTT CTGCTCGTTC TGGGCGGAGG TCAGAGTGAG 
TTAGATACCA AGATTACGTC CTCAGGGGAG ACCACAGAAT GGGAGGATCC TGACCTGTCT 
CCACAGGGAT CCTGCCAGCC AGCTCCTTCC TGCCAGAAGT GTATACTCTC ACACCCCAGC 
TGTGCATGGT GCAAGCAACT GAACTTCACT GCCTCGGGGG AGGCAGAGGC GAGGCGCTGC 
GCGCGGCGTG AGGAGCTACT GGCCCGCGGG TGCCCCGAGC AGGAGCTGGA GGAGCCGAGA 
GGCCACCAGG AGGTGCTGCA GGACAGGCCA CTCAGCCAGG GAGACCGCGG CGAGGGGGCC 
ACCCAGCTGG CCCCGCAGCG GATCCGCGTC ACGTTGCGAC CAGGGGAGCC CCAGAAATTC 
CGGGTCCGCT TCCTCCGAGC TGCGGGATAT CCCGTGGACC TGTACTACCT TATGGACCTG 
AGCTATTCAA TGAAGGACGA CTTGGAACGT GTGCGACAGC TCGGGCAAGC CCTGCTGCTC 
CGGCTGCGGG AGGTCACCCA TTCTGTGCGC ATAGGTTTTG GCTCCTTTGT GGACAAAACG 
GTGCTACCCT TTGTAAGCAC AGTGCCCTCC AAGCTTAACC ACCCATGCCC CAGCCGGTTG 
GAGCGCTGTC AGGCACCCTT CAGCTATCAC CACGTGTTGC CCCTCACCAG GGATGCTCAA 
GCCTTCGAGA GAGAGGTGGG ACGCCAGAAC GTCTCTGGCA ACCTGGACTC ACCCGAAGGA 
GGCTTTGATG CCATTTTGCA GGCTGCTCTT TGCCAGGAGC AGATTGGCTG GAGAAATGTG 
TCCCGGCTTC TGGTGTTCAC TTCAGACGAT ACGTTCCACA CAGCTGGGGA TGGGAAACTG 
GGTGGCATTT TCATGCCCAG CGATGGGCGG TGCCACCTGG ACAGCAACGG TGTCTACACT 
AACAGCGCAG AGTTTGACTA TCCCTCTGTG GGCCAAGTAG CCCAGGCTCT CACAGCAGCG 
AATATCCAAC CTATCTTTGC TGTCACCGGC GCAACACTGC CCGTGTATCA GGAGCTGAGC 
CAGTTGATTC CCAAGTCTGC TGTCGGGGAG CTCAGCGAAG ACTCCAGCAA TGTGGTGCAG 
CTCATCATGG ATGCTTACGA CAACCTGTCA TCCACCGTGA CTCTTGAACA CTCTTCGCTC 
CCACCTGGAG TCAGCATCTC TTTCGAGTCT CACTGTAGGA GTCCTGAGAA GAGTGAGGGT 
GAGGCTGGGG ACCGTCGGGG ACAGTGCAAT CATGTCCGAG TCAACCAGAT GGTGGATTTC 
TGGGTCACTC TTCAAGCCTC TCACTGCCTC CCAGAAGCCC ATGTCCTACG GCTCTGGGCC 
CTTGGCTTCT CAGAGGAGTT AACTGTGGAG CTGCACACAC TGTGTGACTG CAATTGTAGT 
GATGCCCAGC CTCGCGCTCC TTACTGCAGC GATGGACAGG GGGACCTTCA ATGCGGGATA 
TGCAGCTGTG CCCCTGGCCG CCTTGGTCAG CTGTGTGAAT GCTCTGAGGC TGACCTGTCC 
TCCCCAGATT TGGAATCTGG TTGCCGGGCC CCCAATGGGA CAGGGCCCCT GTGCAGCGGG 
AAGGGTCGAT GCCAATGTGG ACGCTGCAGT TGCAGTGGAC AGAGCTCTGG GCGTCTGTGC 
GAGTGTGATG ATGCCAGCTG TGAGCGACAC GAGGGCATCC TCTGTGGAGG CTTTGGCCAC 
TGCCAGTGTG GAGTGTGTCA CTGCCATGCC AACCGCACTG GCAGAGCATG TGAGTGCAGT 
GAGAGTGTGG ACAGCTGCGT TAGTCCCGAA GGAGGGCTCT GCAGTGGGCA TGGTGACTGC 
AAATGCAACC GTTGCCAGTG CCTGGATGGC TACTACGGGG CTCTGTGTGA CCAGTGCCTA 
GGCTGCAAGT CACCATGTGA GCAATACAGG GACTGCGCGG AGTGTGGGGC GTTTGGTACG 
GGTCCCCTGG CAGCCAACTG CAGCGCGGCT TGTGCTGACG TGAATGTGAC CTTGGCCTTG 
GCCCCCAATT TGGATGATGG TTGGTGCAAA GAGAGGACGC TAGACAACCA GCTGTTCTTC 
TTCCTGGTGG AGAATTCGGC CAGAGGGGTC ATACTGAGAG TGAGACCCCA AGAGAAGGGA 
GCAGACCACA CCCGTGCCAT CATACTGGGC TGCGTAGGGG GCATTGTGGC AGTGGGATTA 
GGGCTGGTCC TGGCTTACCG GCTCTCAGTG GAAGTCTATG ACCGCCTTGA GTACAGCCGC 
TTTGAGAAGG AGAGGCAGCA ACTCAACTGG AAGCAGGACA GCAATCCTCT CTACAAAAGT 
GCGGTCACAA CTACCGTCAA CCCTCGCTTC CAAGGGGGCA ACAAACAGTC GCTGTCCCTC 
CCTCTGACCC AGGAGGCTGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037303.1
CDS	1..2424
Translation	MVDSSTVLIFLLVLGGGQSELDTKITSSGETTEWEDPDLSPQGSCQPAPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPEQELEEPRGHQEVLQDRPLSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGQALLLRLREVTHSVRIGFGSFVDKTVLPFVSTVPSKLNHPCPSRLERCQAPFSYHHVLPLTRDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSRLLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELSQLIPKSAVGELSEDSSNVVQLIMDAYDNLSSTVTLEHSSLPPGVSISFESHCRSPEKSEGEAGDRRGQCNHVRVNQMVDFWVTLQASHCLPEAHVLRLWALGFSEELTVELHTLCDCNCSDAQPRAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANRTGRACECSESVDSCVSPEGGLCSGHGDCKCNRCQCLDGYYGALCDQCLGCKSPCEQYRDCAECGAFGTGPLAANCSAACADVNVTLALAPNLDDGWCKERTLDNQLFFFLVENSARGVILRVRPQEKGADHTRAIILGCVGGIVAVGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKSAVTTTVNPRFQGGNKQSLSLPLTQEAD

Target ORF information:

RefSeq Version	NM_013171.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 7 (Itgb7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013171.1

ORF Insert Sequence:

ATGGTGGATT CATCAACTGT TCTCATTTTT CTGCTCGTTC TGGGCGGAGG TCAGAGTGAG 
TTAGATACCA AGATTACGTC CTCAGGGGAG ACCACAGAAT GGGAGGATCC TGACCTGTCT 
CCACAGGGAT CCTGCCAGCC AGCTCCTTCC TGCCAGAAGT GTATACTCTC ACACCCCAGC 
TGTGCATGGT GCAAGCAACT GAACTTCACT GCCTCGGGGG AGGCAGAGGC GAGGCGCTGC 
GCGCGGCGTG AGGAGCTACT GGCCCGCGGG TGCCCCGAGC AGGAGCTGGA GGAGCCGAGA 
GGCCACCAGG AGGTGCTGCA GGACAGGCCA CTCAGCCAGG GAGACCGCGG CGAGGGGGCC 
ACCCAGCTGG CCCCGCAGCG GATCCGCGTC ACGTTGCGAC CAGGGGAGCC CCAGAAATTC 
CGGGTCCGCT TCCTCCGAGC TGCGGGATAT CCCGTGGACC TGTACTACCT TATGGACCTG 
AGCTATTCAA TGAAGGACGA CTTGGAACGT GTGCGACAGC TCGGGCAAGC CCTGCTGCTC 
CGGCTGCGGG AGGTCACCCA TTCTGTGCGC ATAGGTTTTG GCTCCTTTGT GGACAAAACG 
GTGCTACCCT TTGTAAGCAC AGTGCCCTCC AAGCTTAACC ACCCATGCCC CAGCCGGTTG 
GAGCGCTGTC AGGCACCCTT CAGCTATCAC CACGTGTTGC CCCTCACCAG GGATGCTCAA 
GCCTTCGAGA GAGAGGTGGG ACGCCAGAAC GTCTCTGGCA ACCTGGACTC ACCCGAAGGA 
GGCTTTGATG CCATTTTGCA GGCTGCTCTT TGCCAGGAGC AGATTGGCTG GAGAAATGTG 
TCCCGGCTTC TGGTGTTCAC TTCAGACGAT ACGTTCCACA CAGCTGGGGA TGGGAAACTG 
GGTGGCATTT TCATGCCCAG CGATGGGCGG TGCCACCTGG ACAGCAACGG TGTCTACACT 
AACAGCGCAG AGTTTGACTA TCCCTCTGTG GGCCAAGTAG CCCAGGCTCT CACAGCAGCG 
AATATCCAAC CTATCTTTGC TGTCACCGGC GCAACACTGC CCGTGTATCA GGAGCTGAGC 
CAGTTGATTC CCAAGTCTGC TGTCGGGGAG CTCAGCGAAG ACTCCAGCAA TGTGGTGCAG 
CTCATCATGG ATGCTTACGA CAACCTGTCA TCCACCGTGA CTCTTGAACA CTCTTCGCTC 
CCACCTGGAG TCAGCATCTC TTTCGAGTCT CACTGTAGGA GTCCTGAGAA GAGTGAGGGT 
GAGGCTGGGG ACCGTCGGGG ACAGTGCAAT CATGTCCGAG TCAACCAGAT GGTGGATTTC 
TGGGTCACTC TTCAAGCCTC TCACTGCCTC CCAGAAGCCC ATGTCCTACG GCTCTGGGCC 
CTTGGCTTCT CAGAGGAGTT AACTGTGGAG CTGCACACAC TGTGTGACTG CAATTGTAGT 
GATGCCCAGC CTCGCGCTCC TTACTGCAGC GATGGACAGG GGGACCTTCA ATGCGGGATA 
TGCAGCTGTG CCCCTGGCCG CCTTGGTCAG CTGTGTGAAT GCTCTGAGGC TGACCTGTCC 
TCCCCAGATT TGGAATCTGG TTGCCGGGCC CCCAATGGGA CAGGGCCCCT GTGCAGCGGG 
AAGGGTCGAT GCCAATGTGG ACGCTGCAGT TGCAGTGGAC AGAGCTCTGG GCGTCTGTGC 
GAGTGTGATG ATGCCAGCTG TGAGCGACAC GAGGGCATCC TCTGTGGAGG CTTTGGCCAC 
TGCCAGTGTG GAGTGTGTCA CTGCCATGCC AACCGCACTG GCAGAGCATG TGAGTGCAGT 
GAGAGTGTGG ACAGCTGCGT TAGTCCCGAA GGAGGGCTCT GCAGTGGGCA TGGTGACTGC 
AAATGCAACC GTTGCCAGTG CCTGGATGGC TACTACGGGG CTCTGTGTGA CCAGTGCCTA 
GGCTGCAAGT CACCATGTGA GCAATACAGG GACTGCGCGG AGTGTGGGGC GTTTGGTACG 
GGTCCCCTGG CAGCCAACTG CAGCGCGGCT TGTGCTGACG TGAATGTGAC CTTGGCCTTG 
GCCCCCAATT TGGATGATGG TTGGTGCAAA GAGAGGACGC TAGACAACCA GCTGTTCTTC 
TTCCTGGTGG AGAATTCGGC CAGAGGGGTC ATACTGAGAG TGAGACCCCA AGAGAAGGGA 
GCAGACCACA CCCGTGCCAT CATACTGGGC TGCGTAGGGG GCATTGTGGC AGTGGGATTA 
GGGCTGGTCC TGGCTTACCG GCTCTCAGTG GAAGTCTATG ACCGCCTTGA GTACAGCCGC 
TTTGAGAAGG AGAGGCAGCA ACTCAACTGG AAGCAGGACA GCAATCCTCT CTACAAAAGT 
GCGGTCACAA CTACCGTCAA CCCTCGCTTC CAAGGGGGCA ACAAACAGTC GCTGTCCCTC 
CCTCTGACCC AGGAGGCTGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb7 ( XM_006242383.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242445.1 Rattus norvegicus integrin subunit beta 7 (Itgb7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02208
Clone ID Related Accession (Same CDS sequence)	NM_013171.1 , XM_006242383.3
Accession Version	XM_006242383.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242383.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGATT CATCAACTGT TCTCATTTTT CTGCTCGTTC TGGGCGGAGG TCAGAGTGAG 
TTAGATACCA AGATTACGTC CTCAGGGGAG ACCACAGAAT GGGAGGATCC TGACCTGTCT 
CCACAGGGAT CCTGCCAGCC AGCTCCTTCC TGCCAGAAGT GTATACTCTC ACACCCCAGC 
TGTGCATGGT GCAAGCAACT GAACTTCACT GCCTCGGGGG AGGCAGAGGC GAGGCGCTGC 
GCGCGGCGTG AGGAGCTACT GGCCCGCGGG TGCCCCGAGC AGGAGCTGGA GGAGCCGAGA 
GGCCACCAGG AGGTGCTGCA GGACAGGCCA CTCAGCCAGG GAGACCGCGG CGAGGGGGCC 
ACCCAGCTGG CCCCGCAGCG GATCCGCGTC ACGTTGCGAC CAGGGGAGCC CCAGAAATTC 
CGGGTCCGCT TCCTCCGAGC TGCGGGATAT CCCGTGGACC TGTACTACCT TATGGACCTG 
AGCTATTCAA TGAAGGACGA CTTGGAACGT GTGCGACAGC TCGGGCAAGC CCTGCTGCTC 
CGGCTGCGGG AGGTCACCCA TTCTGTGCGC ATAGGTTTTG GCTCCTTTGT GGACAAAACG 
GTGCTACCCT TTGTAAGCAC AGTGCCCTCC AAGCTTAACC ACCCATGCCC CAGCCGGTTG 
GAGCGCTGTC AGGCACCCTT CAGCTATCAC CACGTGTTGC CCCTCACCAG GGATGCTCAA 
GCCTTCGAGA GAGAGGTGGG ACGCCAGAAC GTCTCTGGCA ACCTGGACTC ACCCGAAGGA 
GGCTTTGATG CCATTTTGCA GGCTGCTCTT TGCCAGGAGC AGATTGGCTG GAGAAATGTG 
TCCCGGCTTC TGGTGTTCAC TTCAGACGAT ACGTTCCACA CAGCTGGGGA TGGGAAACTG 
GGTGGCATTT TCATGCCCAG CGATGGGCGG TGCCACCTGG ACAGCAACGG TGTCTACACT 
AACAGCGCAG AGTTTGACTA TCCCTCTGTG GGCCAAGTAG CCCAGGCTCT CACAGCAGCG 
AATATCCAAC CTATCTTTGC TGTCACCGGC GCAACACTGC CCGTGTATCA GGAGCTGAGC 
CAGTTGATTC CCAAGTCTGC TGTCGGGGAG CTCAGCGAAG ACTCCAGCAA TGTGGTGCAG 
CTCATCATGG ATGCTTACGA CAACCTGTCA TCCACCGTGA CTCTTGAACA CTCTTCGCTC 
CCACCTGGAG TCAGCATCTC TTTCGAGTCT CACTGTAGGA GTCCTGAGAA GAGTGAGGGT 
GAGGCTGGGG ACCGTCGGGG ACAGTGCAAT CATGTCCGAG TCAACCAGAT GGTGGATTTC 
TGGGTCACTC TTCAAGCCTC TCACTGCCTC CCAGAAGCCC ATGTCCTACG GCTCTGGGCC 
CTTGGCTTCT CAGAGGAGTT AACTGTGGAG CTGCACACAC TGTGTGACTG CAATTGTAGT 
GATGCCCAGC CTCGCGCTCC TTACTGCAGC GATGGACAGG GGGACCTTCA ATGCGGGATA 
TGCAGCTGTG CCCCTGGCCG CCTTGGTCAG CTGTGTGAAT GCTCTGAGGC TGACCTGTCC 
TCCCCAGATT TGGAATCTGG TTGCCGGGCC CCCAATGGGA CAGGGCCCCT GTGCAGCGGG 
AAGGGTCGAT GCCAATGTGG ACGCTGCAGT TGCAGTGGAC AGAGCTCTGG GCGTCTGTGC 
GAGTGTGATG ATGCCAGCTG TGAGCGACAC GAGGGCATCC TCTGTGGAGG CTTTGGCCAC 
TGCCAGTGTG GAGTGTGTCA CTGCCATGCC AACCGCACTG GCAGAGCATG TGAGTGCAGT 
GAGAGTGTGG ACAGCTGCGT TAGTCCCGAA GGAGGGCTCT GCAGTGGGCA TGGTGACTGC 
AAATGCAACC GTTGCCAGTG CCTGGATGGC TACTACGGGG CTCTGTGTGA CCAGTGCCTA 
GGCTGCAAGT CACCATGTGA GCAATACAGG GACTGCGCGG AGTGTGGGGC GTTTGGTACG 
GGTCCCCTGG CAGCCAACTG CAGCGCGGCT TGTGCTGACG TGAATGTGAC CTTGGCCTTG 
GCCCCCAATT TGGATGATGG TTGGTGCAAA GAGAGGACGC TAGACAACCA GCTGTTCTTC 
TTCCTGGTGG AGAATTCGGC CAGAGGGGTC ATACTGAGAG TGAGACCCCA AGAGAAGGGA 
GCAGACCACA CCCGTGCCAT CATACTGGGC TGCGTAGGGG GCATTGTGGC AGTGGGATTA 
GGGCTGGTCC TGGCTTACCG GCTCTCAGTG GAAGTCTATG ACCGCCTTGA GTACAGCCGC 
TTTGAGAAGG AGAGGCAGCA ACTCAACTGG AAGCAGGACA GCAATCCTCT CTACAAAAGT 
GCGGTCACAA CTACCGTCAA CCCTCGCTTC CAAGGGGGCA ACAAACAGTC GCTGTCCCTC 
CCTCTGACCC AGGAGGCTGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242445.1
CDS	93..2516
Translation	MVDSSTVLIFLLVLGGGQSELDTKITSSGETTEWEDPDLSPQGSCQPAPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPEQELEEPRGHQEVLQDRPLSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGQALLLRLREVTHSVRIGFGSFVDKTVLPFVSTVPSKLNHPCPSRLERCQAPFSYHHVLPLTRDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSRLLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELSQLIPKSAVGELSEDSSNVVQLIMDAYDNLSSTVTLEHSSLPPGVSISFESHCRSPEKSEGEAGDRRGQCNHVRVNQMVDFWVTLQASHCLPEAHVLRLWALGFSEELTVELHTLCDCNCSDAQPRAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANRTGRACECSESVDSCVSPEGGLCSGHGDCKCNRCQCLDGYYGALCDQCLGCKSPCEQYRDCAECGAFGTGPLAANCSAACADVNVTLALAPNLDDGWCKERTLDNQLFFFLVENSARGVILRVRPQEKGADHTRAIILGCVGGIVAVGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKSAVTTTVNPRFQGGNKQSLSLPLTQEAD

Target ORF information:

RefSeq Version	XM_006242383.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 7 (Itgb7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242383.3

ORF Insert Sequence:

ATGGTGGATT CATCAACTGT TCTCATTTTT CTGCTCGTTC TGGGCGGAGG TCAGAGTGAG 
TTAGATACCA AGATTACGTC CTCAGGGGAG ACCACAGAAT GGGAGGATCC TGACCTGTCT 
CCACAGGGAT CCTGCCAGCC AGCTCCTTCC TGCCAGAAGT GTATACTCTC ACACCCCAGC 
TGTGCATGGT GCAAGCAACT GAACTTCACT GCCTCGGGGG AGGCAGAGGC GAGGCGCTGC 
GCGCGGCGTG AGGAGCTACT GGCCCGCGGG TGCCCCGAGC AGGAGCTGGA GGAGCCGAGA 
GGCCACCAGG AGGTGCTGCA GGACAGGCCA CTCAGCCAGG GAGACCGCGG CGAGGGGGCC 
ACCCAGCTGG CCCCGCAGCG GATCCGCGTC ACGTTGCGAC CAGGGGAGCC CCAGAAATTC 
CGGGTCCGCT TCCTCCGAGC TGCGGGATAT CCCGTGGACC TGTACTACCT TATGGACCTG 
AGCTATTCAA TGAAGGACGA CTTGGAACGT GTGCGACAGC TCGGGCAAGC CCTGCTGCTC 
CGGCTGCGGG AGGTCACCCA TTCTGTGCGC ATAGGTTTTG GCTCCTTTGT GGACAAAACG 
GTGCTACCCT TTGTAAGCAC AGTGCCCTCC AAGCTTAACC ACCCATGCCC CAGCCGGTTG 
GAGCGCTGTC AGGCACCCTT CAGCTATCAC CACGTGTTGC CCCTCACCAG GGATGCTCAA 
GCCTTCGAGA GAGAGGTGGG ACGCCAGAAC GTCTCTGGCA ACCTGGACTC ACCCGAAGGA 
GGCTTTGATG CCATTTTGCA GGCTGCTCTT TGCCAGGAGC AGATTGGCTG GAGAAATGTG 
TCCCGGCTTC TGGTGTTCAC TTCAGACGAT ACGTTCCACA CAGCTGGGGA TGGGAAACTG 
GGTGGCATTT TCATGCCCAG CGATGGGCGG TGCCACCTGG ACAGCAACGG TGTCTACACT 
AACAGCGCAG AGTTTGACTA TCCCTCTGTG GGCCAAGTAG CCCAGGCTCT CACAGCAGCG 
AATATCCAAC CTATCTTTGC TGTCACCGGC GCAACACTGC CCGTGTATCA GGAGCTGAGC 
CAGTTGATTC CCAAGTCTGC TGTCGGGGAG CTCAGCGAAG ACTCCAGCAA TGTGGTGCAG 
CTCATCATGG ATGCTTACGA CAACCTGTCA TCCACCGTGA CTCTTGAACA CTCTTCGCTC 
CCACCTGGAG TCAGCATCTC TTTCGAGTCT CACTGTAGGA GTCCTGAGAA GAGTGAGGGT 
GAGGCTGGGG ACCGTCGGGG ACAGTGCAAT CATGTCCGAG TCAACCAGAT GGTGGATTTC 
TGGGTCACTC TTCAAGCCTC TCACTGCCTC CCAGAAGCCC ATGTCCTACG GCTCTGGGCC 
CTTGGCTTCT CAGAGGAGTT AACTGTGGAG CTGCACACAC TGTGTGACTG CAATTGTAGT 
GATGCCCAGC CTCGCGCTCC TTACTGCAGC GATGGACAGG GGGACCTTCA ATGCGGGATA 
TGCAGCTGTG CCCCTGGCCG CCTTGGTCAG CTGTGTGAAT GCTCTGAGGC TGACCTGTCC 
TCCCCAGATT TGGAATCTGG TTGCCGGGCC CCCAATGGGA CAGGGCCCCT GTGCAGCGGG 
AAGGGTCGAT GCCAATGTGG ACGCTGCAGT TGCAGTGGAC AGAGCTCTGG GCGTCTGTGC 
GAGTGTGATG ATGCCAGCTG TGAGCGACAC GAGGGCATCC TCTGTGGAGG CTTTGGCCAC 
TGCCAGTGTG GAGTGTGTCA CTGCCATGCC AACCGCACTG GCAGAGCATG TGAGTGCAGT 
GAGAGTGTGG ACAGCTGCGT TAGTCCCGAA GGAGGGCTCT GCAGTGGGCA TGGTGACTGC 
AAATGCAACC GTTGCCAGTG CCTGGATGGC TACTACGGGG CTCTGTGTGA CCAGTGCCTA 
GGCTGCAAGT CACCATGTGA GCAATACAGG GACTGCGCGG AGTGTGGGGC GTTTGGTACG 
GGTCCCCTGG CAGCCAACTG CAGCGCGGCT TGTGCTGACG TGAATGTGAC CTTGGCCTTG 
GCCCCCAATT TGGATGATGG TTGGTGCAAA GAGAGGACGC TAGACAACCA GCTGTTCTTC 
TTCCTGGTGG AGAATTCGGC CAGAGGGGTC ATACTGAGAG TGAGACCCCA AGAGAAGGGA 
GCAGACCACA CCCGTGCCAT CATACTGGGC TGCGTAGGGG GCATTGTGGC AGTGGGATTA 
GGGCTGGTCC TGGCTTACCG GCTCTCAGTG GAAGTCTATG ACCGCCTTGA GTACAGCCGC 
TTTGAGAAGG AGAGGCAGCA ACTCAACTGG AAGCAGGACA GCAATCCTCT CTACAAAAGT 
GCGGTCACAA CTACCGTCAA CCCTCGCTTC CAAGGGGGCA ACAAACAGTC GCTGTCCCTC 
CCTCTGACCC AGGAGGCTGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disruption of disulfide restriction at integrin knees induces activation and ligand-independent signaling of ????.
Journal of cell science126(Pt 21)5030-41(2013 Nov)
Zhang K,Pan Y,Qi J,Yue J,Zhang M,Xu C,Li G,Chen J

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
Science (New York, N.Y.)340(6139)1456-9(2013 Jun)
Kim SV,Xiang WV,Kwak C,Yang Y,Lin XW,Ota M,Sarpel U,Rifkin DB,Xu R,Littman DR

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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Itgb7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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