Selp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Selp
Entrez Gene ID	25651
Full Name	selectin P
Synonyms	PSELECT
General protein information	Preferred Names selectin P Names P-selectin CD62 antigen-like family member P GMP-140 LECAM3 PADGEM granule membrane protein 140 leukocyte-endothelial cell adhesion molecule 3 platelet activation dependent granule-external membrane protein selectin, platelet
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q23
Summary	mediates leukocyte interaction with platelets and endothelial binding after vascular injury; may play a role in inflammatory response [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013114.1	NP_037246.1	P-selectin precursor
XM_006250150.3	XP_006250212.1	P-selectin isoform X1

Pathways from BioSystems

Homologies

	SELP	XP_001094728.1
Rattus norvegicus (Norway rat)	Selp	NP_037246.1
Xenopus tropicalis (tropical clawed frog)	selp	XP_002933829.2
Homo sapiens (human)	SELP	NP_002996.2
Pan troglodytes (chimpanzee)	SELP	XP_001137240.1
Canis lupus familiaris (dog)	SELP	XP_537202.3
Mus musculus (house mouse)	Selp	NP_035477.1
Gallus gallus (chicken)	SELP	XP_004943196.1
Danio rerio (zebrafish)	selp	NP_001230252.1

Gene Ontology
Bibliography

Related articles in PubMed

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.
Mehta-D'souza P, Klopocki AG, Oganesyan V, Terzyan S, Mather T, Li Z, Panicker SR, Zhu C, McEver RP
The Journal of biological chemistry292(6)2510-2518(2017 02)

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Vogel KU, Edelmann SL, Jeltsch KM, Bertossi A, Heger K, Heinz GA, Z?ller J, Warth SC, Hoefig KP, Lohs C, Neff F, Kremmer E, Schick J, Repsilber D, Geerlof A, Blum H, Wurst W, Heikenw?lder M, Schmidt-Supprian M, Heissmeyer V
Immunity38(4)655-68(2013 Apr)

L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide.
Zhong M, He B, Yang J, Bao R, Zhang Y, Zhou D, Chen Y, Li L, Han C, Yang Y, Sun Y, Cao Y, Li Y, Shi W, Jiang S, Zhang X, Yan H
Antimicrobial agents and chemotherapy56(6)3121-32(2012 Jun)

Plant sterols and casein-derived tripeptides attenuate blood pressure increase in spontaneously hypertensive rats.
Ehlers PI, Kivim?ki AS, Siltari A, Turpeinen AM, Korpela R, Vapaatalo H
Nutrition research (New York, N.Y.)32(4)292-300(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clerodendron glandulosum.Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats.
Title: Clerodendron glandulosum.Coleb leaf extract attenuates in vitro macrophage differentiation and expression of VCAM-1 and P-selectin in thoracic aorta of atherogenic diet fed rats.

Aortic cyclooxygenase-2 and P-selectin were significantly down-regulated in plant sterols and plant sterols + tripeptides groups.
Title: Plant sterols and casein-derived tripeptides attenuate blood pressure increase in spontaneously hypertensive rats.

Fibrinogen can interact with P-selectin in order to contribute to the development of atherosclerosis, high levels of fibrinogen and P-selectin can be regarded as risk factors for markers of atherosclerosis.
Title: Fibrinogen and P-selectin expression in atherosclerosis model of Sprague Dawley rat.

Both baicalin and octreotide can exert some protective effects on multiple organs of rats with severe acute pancreatitis via decreased P-selectin expression.
Title: Effect of baicalin and octreotide on the expression levels of P-selectin protein in multiple organs of rats with severe acute pancreatitis.

Renal injury after ischemia/reperfusion may relate to the strong expression of P-selectin. NO may have a protective affect by decreasing the expression of P-selectin and alleviating the adhesion, aggregation and infiltration of neutrophils.
Title: [The affection and significance of NO on the expression of P-selectin in renal injury following hind limb ischemia/reperfusion in rats].

The following Selp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Selp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02021	NM_013114.1 Latest version!	Rattus norvegicus selectin P (Selp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa35552	XM_006250150.3 Latest version!	Rattus norvegicus selectin P (Selp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Selp ( NM_013114.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037246.1 Rattus norvegicus selectin P (Selp), mRNA.

Price & Availability↑

CloneID	ORa02021
Clone ID Related Accession (Same CDS sequence)	NM_013114.1
Accession Version	NM_013114.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	P-selectin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L23088.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L23088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906355, SAMN02642666 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGGCT GCCCAAAAGG TTCTTGGAAG CCAAGACTCC GGAGTGTAGT CCTGGGAGCA 
GCTCAGCTTA TCTGGCTCAG TGCTTTGATC TCTGAGCTTG TAAATCGAAA GAAAGTGGCG 
ACGTGGACCT ATAACTACAG CACGAAAGCA TACTCATGGA ATAACTCACG GGCATTCTGC 
AAGAGGCACT TCACAGACTT AGTGGCCATC CAGAACAAGA ATGAAATCGC TCACCTCAAT 
GACGTCATCC CATACGTCAA CTCTTACTAC TGGATTGGTA TCCGAAAGAT CAACAATAAG 
TGGACCTGGG TGGGAACCAA TAAGACTCTC ACGGCGGAGG CTGAGAACTG GGCAGACAAC 
GAGCCCAATA ACAAGAGGAA CAACCAGGAC TGTGTGGAGA TCTACATCAA GAGTAATTCG 
GCCCCTGGCA AGTGGAATGA TGAGCCCTGC TTTAAACGAA AGCGGGCCCT GTGCTACACA 
GCCTCCTGCC AGGACATGTC TTGCAACAGC CAAGGGGAGC GCATCGAGAC CATTGGGAGC 
TACACCTGCT CCTGCTACCC GGGCTTCTAT GGGCCAGAGT GTGAATACGT CCAAGAGTGT 
GGAAAATTCG ACATCCCGCA ACACGTTCTC ATGAACTGCA GCCACCCTCT GGGGGACTTC 
TCCTTCAGCT CACAGTGCAC CTTCAGCTGT CCTGAGGGCT ATGACCTGAA CGGACCCAGT 
GAGATGCAAT GTTTGGCCTC TGGAATCTGG ACAAATAATC CCCCGCAGTG TAAAGCTGTG 
CAGTGCCAGA GCCTGGAAGC CCCTCTCCAT GGAACCATGG ACTGTACACA CCCATTGGCT 
GCCTTTGCCT ATGACTCCAG CTGTAAATTT GAGTGCCAGC CTGGATATCG GATGAGGGGC 
TCTGACATAC TCCACTGCAC TGACTCTGGT CAGTGGAGTG AACCATTGCC AACCTGTGAA 
GCCATTGCAT GCGAACCGCT GGAGAGCCCC CTCCATGGGA GCATGGACTG CTTCCCATCC 
ACAGGAGCAT TCGGGTACAA CAGCAGCTGC ACTTTTCGCT GCACAGAGGG ATTCGTGCTG 
ATGGGAAATG ATGCCATTCA TTGTGCTGAC TTGGGGCAGT GGACAGCCCC AGCCCCAGTC 
TGTGAAGCGT TGCAATGTCA GGAGTTTCCG GTCCCAAGTA AAGCCCAGGT GAGCTGCTCG 
GACCCCTTCG GACCCTTGAA GTACCAGTCA GCCTGCAGCT TTTCCTGTGA TGAAGGCTCA 
CTCTTGGTGG GAGCAAGTGT GATAAGATGC TTGGCTACTG GACACTGGAG TGAGGCCCCT 
CCTGAATGTC AAGCTGTCTC CTGCACCCCT TTGCTCAGCC CTGAGAATGG AACCATGACG 
TGTATCCAGC CTCTTGGGCA TTCCAACTAC AAATCCACAT GCCAGTTCAT GTGTGACGAA 
GGATTTTATC TATCTGGACC AGAAAGATTG GACTGTTCTC CATCTGGACA CTGGACAGGC 
AGCCCTCCAA TGTGTGAAGC CATCAAGTGC CCAGAAATCT TTGCCCCAGA ACAAGGCAGC 
TTGGACTGCT CTCATGTTCA TGGAGAATTC AGTGTCGGCT CCACCTGTCA CTTCTCCTGC 
AACGAGGAGT TTGAGCTCCT GGGATCTCGA AATGTGGAGT GCACAGTGTC TGGAAGATGG 
TCAGCGCCTC CACCAACCTG CAAAGGTGTA ACATCACTTC CTGTCCCATC GGTTCGATGC 
CCCGCCCTCA CTACTCCTGG ACAGGGCACA ATGTCCTGTC GACACCACCT GGAAAGCTTT 
GGTCCGAACA CCACTTGTTA CTTTGGGTGC AAAACAGGAT TTACACTCAG AGGAGCCAAC 
TCTCTCCGCT GCGGGGCTTC AGGACAATGG ACAGCAGTGA CGCCCGTGTG CAGAGCCGTC 
AAATGCTCAG AATTGCACAT GGACACAGCA GTCGCGATGA ACTGTTCCAA CCCCTGGGGA 
AACTTTAGCT ACGGATCAAC CTGTGCCTTC CACTGTCCAG AGGGGCAGTC ACTGAATGGC 
TCTGCCAGGA CAACCTGCGG AGAGGACGGT CACTGGTCAG ATGCTATGCC AACCTGCCAA 
GCAGGGACGC TGACGATCCA GGAAGCTCTG ACTTACTTGG GTGGCGCCTT GGCTTCTACT 
TCTGGCCTGG CAGTGGGCGG GACGCTACTG GCTCTGCTAA GAAAGCGTCT CAGAAAGAAA 
GATGATGGAA AATGCCCCCT GAACCCTCAC AGCCACCTAG GAACATATGG AGTCTTCACG 
AACGCTGCAT ATGACCCAAC CCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037246.1
CDS	19..2325
Translation	MAGCPKGSWKPRLRSVVLGAAQLIWLSALISELVNRKKVATWTYNYSTKAYSWNNSRAFCKRHFTDLVAIQNKNEIAHLNDVIPYVNSYYWIGIRKINNKWTWVGTNKTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCNSQGERIETIGSYTCSCYPGFYGPECEYVQECGKFDIPQHVLMNCSHPLGDFSFSSQCTFSCPEGYDLNGPSEMQCLASGIWTNNPPQCKAVQCQSLEAPLHGTMDCTHPLAAFAYDSSCKFECQPGYRMRGSDILHCTDSGQWSEPLPTCEAIACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFVLMGNDAIHCADLGQWTAPAPVCEALQCQEFPVPSKAQVSCSDPFGPLKYQSACSFSCDEGSLLVGASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQPLGHSNYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGSPPMCEAIKCPEIFAPEQGSLDCSHVHGEFSVGSTCHFSCNEEFELLGSRNVECTVSGRWSAPPPTCKGVTSLPVPSVRCPALTTPGQGTMSCRHHLESFGPNTTCYFGCKTGFTLRGANSLRCGASGQWTAVTPVCRAVKCSELHMDTAVAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCGEDGHWSDAMPTCQAGTLTIQEALTYLGGALASTSGLAVGGTLLALLRKRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP

Target ORF information:

RefSeq Version	NM_013114.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin P (Selp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013114.1

ORF Insert Sequence:

ATGGCCGGCT GCCCAAAAGG TTCTTGGAAG CCAAGACTCC GGAGTGTAGT CCTGGGAGCA 
GCTCAGCTTA TCTGGCTCAG TGCTTTGATC TCTGAGCTTG TAAATCGAAA GAAAGTGGCG 
ACGTGGACCT ATAACTACAG CACGAAAGCA TACTCATGGA ATAACTCACG GGCATTCTGC 
AAGAGGCACT TCACAGACTT AGTGGCCATC CAGAACAAGA ATGAAATCGC TCACCTCAAT 
GACGTCATCC CATACGTCAA CTCTTACTAC TGGATTGGTA TCCGAAAGAT CAACAATAAG 
TGGACCTGGG TGGGAACCAA TAAGACTCTC ACGGCGGAGG CTGAGAACTG GGCAGACAAC 
GAGCCCAATA ACAAGAGGAA CAACCAGGAC TGTGTGGAGA TCTACATCAA GAGTAATTCG 
GCCCCTGGCA AGTGGAATGA TGAGCCCTGC TTTAAACGAA AGCGGGCCCT GTGCTACACA 
GCCTCCTGCC AGGACATGTC TTGCAACAGC CAAGGGGAGC GCATCGAGAC CATTGGGAGC 
TACACCTGCT CCTGCTACCC GGGCTTCTAT GGGCCAGAGT GTGAATACGT CCAAGAGTGT 
GGAAAATTCG ACATCCCGCA ACACGTTCTC ATGAACTGCA GCCACCCTCT GGGGGACTTC 
TCCTTCAGCT CACAGTGCAC CTTCAGCTGT CCTGAGGGCT ATGACCTGAA CGGACCCAGT 
GAGATGCAAT GTTTGGCCTC TGGAATCTGG ACAAATAATC CCCCGCAGTG TAAAGCTGTG 
CAGTGCCAGA GCCTGGAAGC CCCTCTCCAT GGAACCATGG ACTGTACACA CCCATTGGCT 
GCCTTTGCCT ATGACTCCAG CTGTAAATTT GAGTGCCAGC CTGGATATCG GATGAGGGGC 
TCTGACATAC TCCACTGCAC TGACTCTGGT CAGTGGAGTG AACCATTGCC AACCTGTGAA 
GCCATTGCAT GCGAACCGCT GGAGAGCCCC CTCCATGGGA GCATGGACTG CTTCCCATCC 
ACAGGAGCAT TCGGGTACAA CAGCAGCTGC ACTTTTCGCT GCACAGAGGG ATTCGTGCTG 
ATGGGAAATG ATGCCATTCA TTGTGCTGAC TTGGGGCAGT GGACAGCCCC AGCCCCAGTC 
TGTGAAGCGT TGCAATGTCA GGAGTTTCCG GTCCCAAGTA AAGCCCAGGT GAGCTGCTCG 
GACCCCTTCG GACCCTTGAA GTACCAGTCA GCCTGCAGCT TTTCCTGTGA TGAAGGCTCA 
CTCTTGGTGG GAGCAAGTGT GATAAGATGC TTGGCTACTG GACACTGGAG TGAGGCCCCT 
CCTGAATGTC AAGCTGTCTC CTGCACCCCT TTGCTCAGCC CTGAGAATGG AACCATGACG 
TGTATCCAGC CTCTTGGGCA TTCCAACTAC AAATCCACAT GCCAGTTCAT GTGTGACGAA 
GGATTTTATC TATCTGGACC AGAAAGATTG GACTGTTCTC CATCTGGACA CTGGACAGGC 
AGCCCTCCAA TGTGTGAAGC CATCAAGTGC CCAGAAATCT TTGCCCCAGA ACAAGGCAGC 
TTGGACTGCT CTCATGTTCA TGGAGAATTC AGTGTCGGCT CCACCTGTCA CTTCTCCTGC 
AACGAGGAGT TTGAGCTCCT GGGATCTCGA AATGTGGAGT GCACAGTGTC TGGAAGATGG 
TCAGCGCCTC CACCAACCTG CAAAGGTGTA ACATCACTTC CTGTCCCATC GGTTCGATGC 
CCCGCCCTCA CTACTCCTGG ACAGGGCACA ATGTCCTGTC GACACCACCT GGAAAGCTTT 
GGTCCGAACA CCACTTGTTA CTTTGGGTGC AAAACAGGAT TTACACTCAG AGGAGCCAAC 
TCTCTCCGCT GCGGGGCTTC AGGACAATGG ACAGCAGTGA CGCCCGTGTG CAGAGCCGTC 
AAATGCTCAG AATTGCACAT GGACACAGCA GTCGCGATGA ACTGTTCCAA CCCCTGGGGA 
AACTTTAGCT ACGGATCAAC CTGTGCCTTC CACTGTCCAG AGGGGCAGTC ACTGAATGGC 
TCTGCCAGGA CAACCTGCGG AGAGGACGGT CACTGGTCAG ATGCTATGCC AACCTGCCAA 
GCAGGGACGC TGACGATCCA GGAAGCTCTG ACTTACTTGG GTGGCGCCTT GGCTTCTACT 
TCTGGCCTGG CAGTGGGCGG GACGCTACTG GCTCTGCTAA GAAAGCGTCT CAGAAAGAAA 
GATGATGGAA AATGCCCCCT GAACCCTCAC AGCCACCTAG GAACATATGG AGTCTTCACG 
AACGCTGCAT ATGACCCAAC CCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Selp ( XM_006250150.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250212.1 Rattus norvegicus selectin P (Selp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa35552
Clone ID Related Accession (Same CDS sequence)	XM_006250150.3
Accession Version	XM_006250150.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2304bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	P-selectin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250150.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCT GCCCAAAAGG TTCTTGGAAG CCAAGACTCC GGAGTGTGGT CCTGGGAGCC 
GCTCAGCTTG TCTGGCTCAG TGCTTTGATC TCTGAGCTTG TAAATCAGAA GGAAGTGGCC 
GCGTGGACCT ATAACTACAG CACGAAAGCA TACTCATGGA ATAACTCACG GGCATTCTGC 
AAGAGGCACT TCACAGACTT AGTGGCCATC CAGAACAAGA ATGAAATCGC TCACCTCAAT 
GACGTCATCC CATACGTCAA CTCTTACTAC TGGATTGGTA TCCGAAAGAT CAACAATAAG 
TGGACCTGGG TGGGAACCAA TAAGACTCTC ACGGCGGAGG CTGAGAACTG GGCAGACAAC 
GAGCCCAACA ACAAGAGGAA CAACCAGGAC TGTGTGGAGA TCTACATCAA GAGTAATTCG 
GCCCCTGGCA AGTGGAATGA TGAGCCCTGC TTTAAACGAA AGCGGGCCCT GTGCTACACA 
GCCTCCTGCC AGGACATGTC TTGCAACAGC CAAGGGGAGT GCATCGAGAC CATTGGGAGC 
TACACCTGCT CCTGCTACCC GGGCTTCTAT GGGCCAGAGT GTGAATACGT CCAAGAGTGT 
GGAAAATTCG ACATCCCGCA ACACGTTCTC ATGAACTGCA GCCACCCTCT GGGGGACTTC 
TCCTTCAGCT CACAGTGCAC CTTCAGCTGT CCTGAGGGCT ATGACCTGAA CGGACCCAGT 
GAGATGCAAT GTTTGGCCTC TGGAATCTGG ACAAATAATC CCCCGCAGTG TAAAGCTGTG 
CAGTGCCAGA GCCTGGAAGC CCCTCTCCAT GGAACCATGG ACTGTACACA CCCATTGGCT 
GCCTTTGCCT ATGACTCCAG CTGTAAATTT GAGTGCCAGC CTGGATATCG GATGAGGGGC 
TCTGACATAC TCCACTGCAC TGACTCTGGT CAGTGGAGTG AACCATTGCC AACCTGTGAA 
GCCATTGCAT GCGAACCGCT GGAGAGCCCC CTCCATGGGA GCATGGACTG CTTCCCATCC 
ACAGGAGCAT TCGGGTACAA CAGCAGCTGC ACTTTTCGCT GCACAGAGGG ATTCGTGCTG 
ATGGGAAATG ATGCCATTCA TTGTGCTGAC TTGGGGCAGT GGACAGCCCC AGCCCCAGTC 
TGTGAAGCGT TGCAATGTCA GGAGTTTCCG GTCCCAAGTA AAGCCCAGGT GAGCTGCTCG 
GACCCCTTCG GGACCTTGAA GTACCAGTCA GCCTGCAGCT TTTCCTGTGA TGAAGGCTCA 
CTCTTGGTGG GAGCAAGTGT GATAAGATGC TTGGCTACTG GACACTGGAG TGAGGCCCCT 
CCTGAATGTC AAGCTGTCTC CTGCACCCCT TTGCTCAGCC CTGAGAATGG AACCATGACG 
TGTATCCAGC CTCTTGGGCA TTCCAACTAC AAATCCACAT GCCAGTTCAT GTGTGACGAA 
GGATTTTATC TATCTGGACC AGAAAGATTG GACTGTTCTC CATCTGGACA CTGGACAGGC 
AGCCCTCCAA TGTGTGAAGC CATCAAGTGC CCAGAAATCT TTGCCCCAGA ACAAGGCAGC 
TTGGACTGCT CTCATGTTCA TGGAGAATTC AGTGTCGGCT CCACCTGTCA CTTCTCCTGC 
AACGAGGAGT TTGAGCTCCT GGGATCTCGA AATGTGGAGT GCACAGTGTC TGGAAGATGG 
TCAGCGCCTC CACCAACCTG CAAAGGTGTA ACATCACTTC CTGTCCCATC GGTTCGATGC 
CCCGCCCTCA CTACTCCTGG ACAGGGCACA ATGTCCTGTC GACACCACCT GGAAAGCTTT 
GGTCCGAACA CCACTTGTTA CTTTGGGTGC AAAACTGGAT TTACACTCAG AGGAGCCAAC 
TCTCTCCGCT GCGGGGCTTC AGGACAATGG ACAGCAGTGA CGCCCGTGTG CAGAGCCGTC 
AAATGCTCAG AATTGCACAT GGACACAGCA GTCGCGATGA ACTGTTCCAA CCCCTGGGGA 
AACTTTAGCT ACGGATCAAC CTGTGCCTTC CACTGTCCAG AGGGGCAGTC ACTGAATGGC 
TCTGCCAGGA CAACCTGCCG AGAGGACGGT CACTGGTCAG ATGCCATGCC AACCTGCCAA 
GGGACGCTGA CGATCCAGGA AGCTCTGACT TACTTGGGTG GCGCCTTGGC TTCTACAACA 
GGCCTGGCAG TGGGCGGGAC GCTACTGGCT CTGCTAAGAA AGCGTCTCAG AAAGAAAGAT 
GATGGAAAAT GCCCCCTGAA CCCTCACAGC CACCTAGGAA CATATGGAGT CTTCACGAAC 
GCTGCATATG ACCCAACCCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250212.1
CDS	162..2465
Translation	MAGCPKGSWKPRLRSVVLGAAQLVWLSALISELVNQKEVAAWTYNYSTKAYSWNNSRAFCKRHFTDLVAIQNKNEIAHLNDVIPYVNSYYWIGIRKINNKWTWVGTNKTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCNSQGECIETIGSYTCSCYPGFYGPECEYVQECGKFDIPQHVLMNCSHPLGDFSFSSQCTFSCPEGYDLNGPSEMQCLASGIWTNNPPQCKAVQCQSLEAPLHGTMDCTHPLAAFAYDSSCKFECQPGYRMRGSDILHCTDSGQWSEPLPTCEAIACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFVLMGNDAIHCADLGQWTAPAPVCEALQCQEFPVPSKAQVSCSDPFGTLKYQSACSFSCDEGSLLVGASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQPLGHSNYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGSPPMCEAIKCPEIFAPEQGSLDCSHVHGEFSVGSTCHFSCNEEFELLGSRNVECTVSGRWSAPPPTCKGVTSLPVPSVRCPALTTPGQGTMSCRHHLESFGPNTTCYFGCKTGFTLRGANSLRCGASGQWTAVTPVCRAVKCSELHMDTAVAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCREDGHWSDAMPTCQGTLTIQEALTYLGGALASTTGLAVGGTLLALLRKRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP

Target ORF information:

RefSeq Version	XM_006250150.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin P (Selp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250150.3

ORF Insert Sequence:

ATGGCCGGCT GCCCAAAAGG TTCTTGGAAG CCAAGACTCC GGAGTGTGGT CCTGGGAGCC 
GCTCAGCTTG TCTGGCTCAG TGCTTTGATC TCTGAGCTTG TAAATCAGAA GGAAGTGGCC 
GCGTGGACCT ATAACTACAG CACGAAAGCA TACTCATGGA ATAACTCACG GGCATTCTGC 
AAGAGGCACT TCACAGACTT AGTGGCCATC CAGAACAAGA ATGAAATCGC TCACCTCAAT 
GACGTCATCC CATACGTCAA CTCTTACTAC TGGATTGGTA TCCGAAAGAT CAACAATAAG 
TGGACCTGGG TGGGAACCAA TAAGACTCTC ACGGCGGAGG CTGAGAACTG GGCAGACAAC 
GAGCCCAACA ACAAGAGGAA CAACCAGGAC TGTGTGGAGA TCTACATCAA GAGTAATTCG 
GCCCCTGGCA AGTGGAATGA TGAGCCCTGC TTTAAACGAA AGCGGGCCCT GTGCTACACA 
GCCTCCTGCC AGGACATGTC TTGCAACAGC CAAGGGGAGT GCATCGAGAC CATTGGGAGC 
TACACCTGCT CCTGCTACCC GGGCTTCTAT GGGCCAGAGT GTGAATACGT CCAAGAGTGT 
GGAAAATTCG ACATCCCGCA ACACGTTCTC ATGAACTGCA GCCACCCTCT GGGGGACTTC 
TCCTTCAGCT CACAGTGCAC CTTCAGCTGT CCTGAGGGCT ATGACCTGAA CGGACCCAGT 
GAGATGCAAT GTTTGGCCTC TGGAATCTGG ACAAATAATC CCCCGCAGTG TAAAGCTGTG 
CAGTGCCAGA GCCTGGAAGC CCCTCTCCAT GGAACCATGG ACTGTACACA CCCATTGGCT 
GCCTTTGCCT ATGACTCCAG CTGTAAATTT GAGTGCCAGC CTGGATATCG GATGAGGGGC 
TCTGACATAC TCCACTGCAC TGACTCTGGT CAGTGGAGTG AACCATTGCC AACCTGTGAA 
GCCATTGCAT GCGAACCGCT GGAGAGCCCC CTCCATGGGA GCATGGACTG CTTCCCATCC 
ACAGGAGCAT TCGGGTACAA CAGCAGCTGC ACTTTTCGCT GCACAGAGGG ATTCGTGCTG 
ATGGGAAATG ATGCCATTCA TTGTGCTGAC TTGGGGCAGT GGACAGCCCC AGCCCCAGTC 
TGTGAAGCGT TGCAATGTCA GGAGTTTCCG GTCCCAAGTA AAGCCCAGGT GAGCTGCTCG 
GACCCCTTCG GGACCTTGAA GTACCAGTCA GCCTGCAGCT TTTCCTGTGA TGAAGGCTCA 
CTCTTGGTGG GAGCAAGTGT GATAAGATGC TTGGCTACTG GACACTGGAG TGAGGCCCCT 
CCTGAATGTC AAGCTGTCTC CTGCACCCCT TTGCTCAGCC CTGAGAATGG AACCATGACG 
TGTATCCAGC CTCTTGGGCA TTCCAACTAC AAATCCACAT GCCAGTTCAT GTGTGACGAA 
GGATTTTATC TATCTGGACC AGAAAGATTG GACTGTTCTC CATCTGGACA CTGGACAGGC 
AGCCCTCCAA TGTGTGAAGC CATCAAGTGC CCAGAAATCT TTGCCCCAGA ACAAGGCAGC 
TTGGACTGCT CTCATGTTCA TGGAGAATTC AGTGTCGGCT CCACCTGTCA CTTCTCCTGC 
AACGAGGAGT TTGAGCTCCT GGGATCTCGA AATGTGGAGT GCACAGTGTC TGGAAGATGG 
TCAGCGCCTC CACCAACCTG CAAAGGTGTA ACATCACTTC CTGTCCCATC GGTTCGATGC 
CCCGCCCTCA CTACTCCTGG ACAGGGCACA ATGTCCTGTC GACACCACCT GGAAAGCTTT 
GGTCCGAACA CCACTTGTTA CTTTGGGTGC AAAACTGGAT TTACACTCAG AGGAGCCAAC 
TCTCTCCGCT GCGGGGCTTC AGGACAATGG ACAGCAGTGA CGCCCGTGTG CAGAGCCGTC 
AAATGCTCAG AATTGCACAT GGACACAGCA GTCGCGATGA ACTGTTCCAA CCCCTGGGGA 
AACTTTAGCT ACGGATCAAC CTGTGCCTTC CACTGTCCAG AGGGGCAGTC ACTGAATGGC 
TCTGCCAGGA CAACCTGCCG AGAGGACGGT CACTGGTCAG ATGCCATGCC AACCTGCCAA 
GGGACGCTGA CGATCCAGGA AGCTCTGACT TACTTGGGTG GCGCCTTGGC TTCTACAACA 
GGCCTGGCAG TGGGCGGGAC GCTACTGGCT CTGCTAAGAA AGCGTCTCAG AAAGAAAGAT 
GATGGAAAAT GCCCCCTGAA CCCTCACAGC CACCTAGGAA CATATGGAGT CTTCACGAAC 
GCTGCATATG ACCCAACCCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.
The Journal of biological chemistry292(6)2510-2518(2017 02)
Mehta-D'souza P,Klopocki AG,Oganesyan V,Terzyan S,Mather T,Li Z,Panicker SR,Zhu C,McEver RP

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Immunity38(4)655-68(2013 Apr)
Vogel KU,Edelmann SL,Jeltsch KM,Bertossi A,Heger K,Heinz GA,Z?ller J,Warth SC,Hoefig KP,Lohs C,Neff F,Kremmer E,Schick J,Repsilber D,Geerlof A,Blum H,Wurst W,Heikenw?lder M,Schmidt-Supprian M,Heissmeyer V

L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide.
Antimicrobial agents and chemotherapy56(6)3121-32(2012 Jun)
Zhong M,He B,Yang J,Bao R,Zhang Y,Zhou D,Chen Y,Li L,Han C,Yang Y,Sun Y,Cao Y,Li Y,Shi W,Jiang S,Zhang X,Yan H

Plant sterols and casein-derived tripeptides attenuate blood pressure increase in spontaneously hypertensive rats.
Nutrition research (New York, N.Y.)32(4)292-300(2012 Apr)
Ehlers PI,Kivim?ki AS,Siltari A,Turpeinen AM,Korpela R,Vapaatalo H

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Selp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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