Il7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il7
Entrez Gene ID	25647
Full Name	interleukin 7
General protein information	Preferred Names interleukin 7 Names interleukin-7 IL-7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q23
Summary	hematopoietic cytokine; involved in immune response and brain tumor growth [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006232139.3	XP_006232201.1	interleukin-7 isoform X1
NM_013110.2	NP_037242.2	interleukin-7 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IL7	NP_001041603.1
Rattus norvegicus (Norway rat)	Il7	NP_037242.2
Homo sapiens (human)	IL7	NP_000871.1
Pan troglodytes (chimpanzee)	IL7	XP_519820.2
Bos taurus (cattle)	IL7	NP_776349.1
Mus musculus (house mouse)	Il7	NP_032397.1
	IL7	NP_001028018.1

Gene Ontology
Bibliography

Related articles in PubMed

TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5).
Chen XL, Serrano D, Ghobadi F, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S
PloS one11(3)e0151837(2016)

Hypoxic stress and IL-7 gene overexpression enhance the fusion potential of rat bone marrow mesenchymal stem cells with bovine renal epithelial cells.
Habib R, Haneef K, Naeem N, Khan I, Jamall S, Atta-Ur-Rahman, Salim A
Molecular and cellular biochemistry403(1-2)125-37(2015 May)

A Special Ingredient (VtR) Containing Oligostilbenes Isolated from Vitis thunbergii Prevents Bone Loss in Ovariectomized Mice: In Vitro and In Vivo Study.
Huang YL, Liu YW, Huang YJ, Chiou WF
Evidence-based complementary and alternative medicine : eCAM2013409421(2013)

Biomarkers of basic activities of daily living in Alzheimer's disease.
Hall JR, Johnson LA, Barber RC, Vo HT, Winter AS, O'Bryant SE,
Journal of Alzheimer's disease : JAD31(2)429-37(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.
Title: TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5).

hypoxic stress and IL-7 overexpression can enhance the renal regeneration potential of mesenchymal stem cells.
Title: Hypoxic stress and IL-7 gene overexpression enhance the fusion potential of rat bone marrow mesenchymal stem cells with bovine renal epithelial cells.

oocyte-derived interleukin 7 could act on neighboring granulosa cells as a survival factor and promote the nuclear maturation of preovulatory oocytes through activation of the PIK3/AKT pathway
Title: Oocyte-expressed interleukin 7 suppresses granulosa cell apoptosis and promotes oocyte maturation in rats.

presence of a mechanism by which gammadelta + T cells are increased in the intestinal villi, through different signaling path ways mediated by CCl25 and IL-7
Title: Importance of CCL25 in the attraction of T cells and the role of IL-7 on the signaling pathways in intestinal epithelial cells.

The following Il7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02011	NM_013110.2 Latest version!	Rattus norvegicus interleukin 7 (Il7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa24532	XM_006232139.3 Latest version!	Rattus norvegicus interleukin 7 (Il7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il7 ( NM_013110.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037242.2 Rattus norvegicus interleukin 7 (Il7), mRNA.

Price & Availability↑

CloneID	ORa02011
Clone ID Related Accession (Same CDS sequence)	NM_013110.2
Accession Version	NM_013110.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-7 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF367210.1. On or before Jun 21, 2005 this sequence version replaced XM_579371.1, NM_013110.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF367210.1, FQ226549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCATG TTTCTTTTAG ATATATCTTT GGAATTCCTC CCCTGATCCT TGTGCTGCTG 
CCGGTCACAT CGTCTGACTG TCACATTAAA GACAAGGACG GTAAAGCCTT TGGGAGTGTG 
CTGATGATCA GCATCAATCA ACTGGACAAA ATGACAGGAA CTGATAGTGA TTGCCCAAAT 
AATGAACCAA ACTTTTTTAA AAAACATCTA TGTGATGATA CAAAGGAAGC TGCTTTTCTA 
AATCGTGCTG CTCGCAAGTT GAGGCAATTT CTTAAAATGA ATATCAGTGA GGAATTCAAT 
GACCATTTAC TAAGAGTTTC AGACGGCACA CAAACACTGG TGAACTGCAC AAGCAAGGAA 
GAAAAAACCA TAAAGGAACA GAAAAAGAAT GATCCATGTT TCCTAAAGAG ACTACTGAGA 
GAGATAAAAA CTTGTTGGAA TAAAATCTTG AACAGCAGTA TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037242.2
CDS	12..476
Translation	MFHVSFRYIFGIPPLILVLLPVTSSDCHIKDKDGKAFGSVLMISINQLDKMTGTDSDCPNNEPNFFKKHLCDDTKEAAFLNRAARKLRQFLKMNISEEFNDHLLRVSDGTQTLVNCTSKEEKTIKEQKKNDPCFLKRLLREIKTCWNKILNSSI

Target ORF information:

RefSeq Version	NM_013110.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 7 (Il7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013110.2

ORF Insert Sequence:

ATGTTCCATG TTTCTTTTAG ATATATCTTT GGAATTCCTC CCCTGATCCT TGTGCTGCTG 
CCGGTCACAT CGTCTGACTG TCACATTAAA GACAAGGACG GTAAAGCCTT TGGGAGTGTG 
CTGATGATCA GCATCAATCA ACTGGACAAA ATGACAGGAA CTGATAGTGA TTGCCCAAAT 
AATGAACCAA ACTTTTTTAA AAAACATCTA TGTGATGATA CAAAGGAAGC TGCTTTTCTA 
AATCGTGCTG CTCGCAAGTT GAGGCAATTT CTTAAAATGA ATATCAGTGA GGAATTCAAT 
GACCATTTAC TAAGAGTTTC AGACGGCACA CAAACACTGG TGAACTGCAC AAGCAAGGAA 
GAAAAAACCA TAAAGGAACA GAAAAAGAAT GATCCATGTT TCCTAAAGAG ACTACTGAGA 
GAGATAAAAA CTTGTTGGAA TAAAATCTTG AACAGCAGTA TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il7 ( XM_006232139.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232201.1 Rattus norvegicus interleukin 7 (Il7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24532
Clone ID Related Accession (Same CDS sequence)	XM_006232139.3
Accession Version	XM_006232139.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232139.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCCATG TTTCTTTTAG ATATATCTTT GGAATTCCTC CCCTGATCCT TGTGCTGCTG 
CCGGTCACAT CGTCTGACTG TCACATTAAA GACAAGGACG GTAAAGCCTT TGGGAGTGTG 
CTGATGATCA GCATCAATCA ACTGGACAAA ATGACAGGAA CTGATAGTGA TTGCCCAAAT 
AATGAACCAA ACTTTTTTAA AAAACATCTA TGTGATGATA CAAAGGAAGC TGCTTTTCTA 
AATCGTGCTG CTCGCAAGTT GAGGCAATTT CTTAAAATGA ATATCAGTGA GGAATTCAAT 
GACCATTTAC TAAGAGTTTC AGACGGCACA CAAACACTGG TGAACTGCAC AAGCAAGGTA 
TTCCCCTACT CTAGAACAAA GCCTCGGCCT TCGGGAAGCT ACTCAAGCCT TGGCTGCAAA 
GTCACAAAGC CCATTTGGAT CTGCTTTCAA AGATTAACCA CTCAGGGACA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232201.1
CDS	2896..3369
Translation	MFHVSFRYIFGIPPLILVLLPVTSSDCHIKDKDGKAFGSVLMISINQLDKMTGTDSDCPNNEPNFFKKHLCDDTKEAAFLNRAARKLRQFLKMNISEEFNDHLLRVSDGTQTLVNCTSKVFPYSRTKPRPSGSYSSLGCKVTKPIWICFQRLTTQGH

Target ORF information:

RefSeq Version	XM_006232139.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 7 (Il7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232139.3

ORF Insert Sequence:

ATGTTCCATG TTTCTTTTAG ATATATCTTT GGAATTCCTC CCCTGATCCT TGTGCTGCTG 
CCGGTCACAT CGTCTGACTG TCACATTAAA GACAAGGACG GTAAAGCCTT TGGGAGTGTG 
CTGATGATCA GCATCAATCA ACTGGACAAA ATGACAGGAA CTGATAGTGA TTGCCCAAAT 
AATGAACCAA ACTTTTTTAA AAAACATCTA TGTGATGATA CAAAGGAAGC TGCTTTTCTA 
AATCGTGCTG CTCGCAAGTT GAGGCAATTT CTTAAAATGA ATATCAGTGA GGAATTCAAT 
GACCATTTAC TAAGAGTTTC AGACGGCACA CAAACACTGG TGAACTGCAC AAGCAAGGTA 
TTCCCCTACT CTAGAACAAA GCCTCGGCCT TCGGGAAGCT ACTCAAGCCT TGGCTGCAAA 
GTCACAAAGC CCATTTGGAT CTGCTTTCAA AGATTAACCA CTCAGGGACA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5).
PloS one11(3)e0151837(2016)
Chen XL,Serrano D,Ghobadi F,Mayhue M,Hoebe K,Ilangumaran S,Ramanathan S

Hypoxic stress and IL-7 gene overexpression enhance the fusion potential of rat bone marrow mesenchymal stem cells with bovine renal epithelial cells.
Molecular and cellular biochemistry403(1-2)125-37(2015 May)
Habib R,Haneef K,Naeem N,Khan I,Jamall S,Atta-Ur-Rahman,Salim A

A Special Ingredient (VtR) Containing Oligostilbenes Isolated from Vitis thunbergii Prevents Bone Loss in Ovariectomized Mice: In Vitro and In Vivo Study.
Evidence-based complementary and alternative medicine : eCAM2013409421(2013)
Huang YL,Liu YW,Huang YJ,Chiou WF

Biomarkers of basic activities of daily living in Alzheimer's disease.
Journal of Alzheimer's disease : JAD31(2)429-37(2012)
Hall JR,Johnson LA,Barber RC,Vo HT,Winter AS,O'Bryant SE,

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Il7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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