gRNAs
The following Hnf1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hnf1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa43183 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013103.2 | |
| Accession Version | NM_013103.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | hepatocyte nuclear factor 1-beta isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030147.1 and AC105531.5. On Apr 28, 2015 this sequence version replaced NM_013103.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is one aa shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081826.1, X56546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_037235.1 |
| CDS | 152..1825 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_013103.2 |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa43182 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001308149.1 | |
| Accession Version | NM_001308149.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | hepatocyte nuclear factor 1-beta isoform 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030147.1 and AC105531.5. Transcript Variant: This variant (3) uses an alternate in-frame splice junction in the 5' end compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF121974.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001295078.1 |
| CDS | 152..1750 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001308149.1 |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa43184 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001308148.1 | |
| Accession Version | NM_001308148.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | hepatocyte nuclear factor 1-beta isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030147.1 and AC105531.5. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF121973.1, EF122006.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001295077.1 |
| CDS | 152..1828 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001308148.1 |
1 | ATGGTGTCCA AGCTCACGTC TCTCCAGCAA GAACTCCTGA GTGCCCTGCT GAGCTCCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. |
HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. |
Upregulation of HNF-1? during experimental acute kidney injury plays a crucial role in renal tubule regeneration. |
The nephrogenic potential of the transcription factors osr1, osr2, hnf1b, lhx1 and pax8 assessed in Xenopus animal caps. |
vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis. |
