G6pc cDNA ORF clone, Rattus norvegicus(Norway rat)

1,2-Dichloroethane impairs glucose and lipid homeostasis in the livers of NIH Swiss mice.
Wang T, Xu D, Fan Q, Rong W, Zheng J, Gao C, Li G, Zeng N, Guo T, Zeng L, Wang F, Xiao C, Cai L, Tang S, Deng X, Yin X, Huang M, Lu F, Hu Q, Chen W, Huang Z, Wang Q
Toxicology38038-49(2017 04)

Glycogen storage disease type Ia mice with less than 2% of normal hepatic glucose-6-phosphatase-? activity restored are at risk of developing hepatic tumors.
Kim GY, Lee YM, Kwon JH, Cho JH, Pan CJ, Starost MF, Mansfield BC, Chou JY
Molecular genetics and metabolism120(3)229-234(2017 Mar)

Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db?mice.
Kong Q, Zhang H, Zhao T, Zhang W, Yan M, Dong X, Li P
International journal of molecular medicine38(6)1715-1726(2016 Dec)

we demonstrate an essential role for fructose 2,6-bisphosphate in the induction of glucose-6-phosphatase and other ChREBP target genes
Title: Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes.

An increase in G6Pase activity was observed in liver microsomes from rats starved overnight, which presented a ~15% decrease in hepatic Mg(2+) content.
Title: Enhanced glucose 6-phosphatase activity in liver of rats exposed to Mg(2+)-deficient diet.

The lower sensitivity of the liver nuclear envelope G-6-Pase to N-ethylmaleimide suggests that the catalytic subunit of this system has some differences from the microsomal isoform.
Title: [Glucose-6-phosphatase from nuclear envelope in rat liver].

Calorie restriction can inhibit the expressions of FoxO1, PEPCK and G-6-P, strengthen insulin signal conduction, suppress gluconeogenesis and thus regulate glycometabolism.
Title: [The effect of calorie restriction on the expression of liver's gluconeogenesis genes of rats fed a high fat diet].

The effect, which is lost when G6P has readily access to the ER lumen, requires physiological endoplasmic reticulum Mg(2+) content.
Title: Biphasic effect of extra-reticular Mg2+ on hepatic G6P transport and hydrolysis.