Sele cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sele
Entrez Gene ID	25544
Full Name	selectin E
General protein information	Preferred Names selectin E Names E-selectin CD62 antigen-like family member E ELAM-1 LECAM2 endothelial leukocyte adhesion molecule 1 leukocyte-endothelial cell adhesion molecule 2 selectin, endothelial cell
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q23
Summary	facilitates recruitment of leukocytes into sites of inflammation; plays a role in cell adhesion [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017598678.1	XP_017454167.1	E-selectin isoform X1
XM_008769608.2	XP_008767830.1	E-selectin isoform X2
NM_138879.1	NP_620234.1	E-selectin precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sele	NP_035475.1
Homo sapiens (human)	SELE	NP_000441.2
	SELE	XP_001094967.1
Canis lupus familiaris (dog)	SELE	NP_001003310.1
Rattus norvegicus (Norway rat)	Sele	NP_620234.1
Pan troglodytes (chimpanzee)	SELE	XP_001137309.1
Gallus gallus (chicken)	SELE	XP_422246.4

Gene Ontology
Bibliography

Related articles in PubMed

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.
Mehta-D'souza P, Klopocki AG, Oganesyan V, Terzyan S, Mather T, Li Z, Panicker SR, Zhu C, McEver RP
The Journal of biological chemistry292(6)2510-2518(2017 02)

Hypoxia inhibits pulmonary artery endothelial cell apoptosis via the e-selectin/biliverdin reductase pathway.
Song S, Yi Z, Zhang M, Mao M, Fu L, Zhao X, Liu Z, Gao J, Cao W, Liu Y, Shi H, Zhu D
Microvascular research10644-56(2016 07)

Testosterone decreases the expression of endometrial pinopode and L-selectin ligand (MECA-79) in adult female rats during uterine receptivity period.
Mokhtar HM, Giribabu N, Muniandy S, Salleh N
International journal of clinical and experimental pathology7(5)1967-76(2014)

Age-dependent modifications in vascular adhesion molecules and apoptosis after 48-h reperfusion in a rat global cerebral ischemia model.
Anuncibay-Soto B, P?rez-Rodr?guez D, Llorente IL, Regueiro-Purri?os M, Gonzalo-Orden JM, Fern?ndez-L?pez A
Age (Dordrecht, Netherlands)36(5)9703(2014)

Atypical antipsychotics such as risperidone, but not paliperidone, worsen vascular endothelial function via upregulation of adhesion molecules VCAM-1, ICAM-1, and E-selectin in diabetic rats.
Aboul-Fotouh S, Elgayar N
Canadian journal of physiology and pharmacology91(12)1119-26(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The e-selectin/biliverdin reductase pathway participates in the inhibitory process of hypoxia in pulmonary artery endothelial cell apoptosis which is mediated by the mitochondrial-dependent apoptosis pathway.
Title: Hypoxia inhibits pulmonary artery endothelial cell apoptosis via the e-selectin/biliverdin reductase pathway.

Decrease in uterine pinopodes and L-selectin ligand MECA-79 expression during uterine receptivity period by testosterone may cause failure of blastocyst implantation.
Title: Testosterone decreases the expression of endometrial pinopode and L-selectin ligand (MECA-79) in adult female rats during uterine receptivity period.

Expression of E-selectin and CAMs was also modified in an age- and ischemia/reperfusion-dependent manner.
Title: Age-dependent modifications in vascular adhesion molecules and apoptosis after 48-h reperfusion in a rat global cerebral ischemia model.

Upregulation of the adhesion molecules VCAM-1, ICAM-1, and E-selectin.
Title: Atypical antipsychotics such as risperidone, but not paliperidone, worsen vascular endothelial function via upregulation of adhesion molecules VCAM-1, ICAM-1, and E-selectin in diabetic rats.

E-selectin blockade similarly inhibits the migration of activated CCR4(negative) and CCR4(positive) CD4 T cells to dermal inflammation.
Title: Differing requirements for CCR4, E-selectin, and ?4?1 for the migration of memory CD4 and activated T cells to dermal inflammation.

The following Sele gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sele cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01853	NM_138879.1 Latest version!	Rattus norvegicus selectin E (Sele), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43141	XM_008769608.2 Latest version!	Rattus norvegicus selectin E (Sele), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa58004	XM_017598678.1 Latest version!	Rattus norvegicus selectin E (Sele), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sele ( NM_138879.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620234.1 Rattus norvegicus selectin E (Sele), mRNA.

Price & Availability↑

CloneID	ORa01853
Clone ID Related Accession (Same CDS sequence)	NM_138879.1
Accession Version	NM_138879.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	E-selectin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L25527.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L25527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGAATGCCT CGTGCTTTCT CTCTGCTCTC ACCTTTGTTC TCCTCATTGG AAAGAGCATA 
GCTTGGTACT ACAATGCCTC CAGTGAGCTC ATGACATATG ATGAAGCAAG TGCGTATTGT 
CAACGGGACT ACACACATCT GGTGGCGATT CAGAACAAGG AAGAGATCAA TTACCTAAAC 
TCCACTCTGA GGTATTCACC AAGTTATTAC TGGATTGGAA TCAGAAAAGT CAATAATGTA 
TGGATCTGGG TGGGGACCCA GAAGCCTCTG ACGGAGGAAG CTAAGAACTG GGCGCCAGGT 
GAACCAAACA ACAAACAAAG AAACGAGGAC TGTGTAGAGA TCTACATCCA AAGACCCAAA 
GACTCCGGCA TGTGGAATGA CGAGAGATGT GACAAAAAGA AACTGGCTCT GTGTTACACA 
GCTTCCTGTA CCAACACATC CTGCAGTGGT CACGGTGAAT GCGTTGAGAC CATCAATAGT 
TATACCTGCA AATGTCACCC CGGCTTCCTG GGACCCAAGT GTGACCAAGT TGTGACCTGC 
CAAGAACAGG AATACCCTGA CCATGGAAGC CTGAACTGCA CCCACCCATT CGGCCTCTTC 
AGCTATAATT CATCCTGCTC CTTCAGCTGT GAAAGGGGCT ATGTGCCCAG CAGCATGGAG 
ACCACAGTGC GGTGTACGTC CTCTGGAGAG TGGAGTGCAC CTGCTCCTGC CTGCCATGTG 
GTTGAATGTA AAGCTTTGAC CCAACCTGCC CACGGAGTCA GGAAATGTTC CTCAAATCCT 
GGGAGCTACC CATGGAATAC AACGTGCACG TTTGATTGTG AGGAAGGGTA CAGGAGAGTT 
GGAGCTCAGA ATCTACAGTG TACCTCATCC GGTGTCTGGG ACAACGAGAA GCCATCGTGC 
AAAGCTGTGA CCTGTGATGC CATCCCTCGG CCTCAGAATG GCTCTGTGAG CTGCAGCAAC 
TCAACGGCTG GAGCGCTTGC CTTTAAGTCT TCCTGTAATT TTACCTGTGA GCACAGTTTC 
ACATTGCAGG GCCCAGCCCA GGTTGAATGC AGTGCACAAG GGCAGTGGAC ACCACAAATC 
CCAGTGTGCA AAGCTTCCCA GTGTGAAGCC TTATCTGCAC CACAGCGAGG CCACATGAAA 
TGTCTTCCCA GTGCCTCTGC ACCCTTCCAA AGTGGGTCCA GTTGTAAGTT CTCCTGTGAC 
GAAGGATTTG AATTGAAGGG ATCAAGAAGG CTTCAGTGTG GTCCAAGAGG GGAGTGGGAC 
AGCGAAAAGC CCACATGTGC AGGGGTACAG TGTTCAAGCC TTGACCTTCC AGGAAAGATG 
AACATGAGTT GCAGTGGGCC AGCAGTTTTT GGCACGGTAT GTGAATTTAC ATGTCCTGAG 
GGTTGGACAC TCAACGGATC TTCAATCCTG ACATGTGGTG CCACAGGACG CTGGTCTGCG 
ATGCTGCCTA CTTGTGAAGC CCCAGCCAAC CCTCCCCGTC CCTTGGTAGT GGCACTCTCT 
GTGGCAGCAA CCTCACTTCT GACATTGTCC TCATTGATCT ACGTGTTGAA GAGATTCTTT 
TGGAAGAAAG CAAAGAAATT CGTTCCTGCT AGTAGCTGCC AAAGTCTTCA ATCGTTTGAA 
AACTATCAAG GGCCTTCTTA CATCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620234.1
CDS	1..1650
Translation	MNASCFLSALTFVLLIGKSIAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLRYSPSYYWIGIRKVNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETINSYTCKCHPGFLGPKCDQVVTCQEQEYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAGVQCSSLDLPGKMNMSCSGPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRPLVVALSVAATSLLTLSSLIYVLKRFFWKKAKKFVPASSCQSLQSFENYQGPSYII

Target ORF information:

RefSeq Version	NM_138879.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin E (Sele), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138879.1

ORF Insert Sequence:

ATGAATGCCT CGTGCTTTCT CTCTGCTCTC ACCTTTGTTC TCCTCATTGG AAAGAGCATA 
GCTTGGTACT ACAATGCCTC CAGTGAGCTC ATGACATATG ATGAAGCAAG TGCGTATTGT 
CAACGGGACT ACACACATCT GGTGGCGATT CAGAACAAGG AAGAGATCAA TTACCTAAAC 
TCCACTCTGA GGTATTCACC AAGTTATTAC TGGATTGGAA TCAGAAAAGT CAATAATGTA 
TGGATCTGGG TGGGGACCCA GAAGCCTCTG ACGGAGGAAG CTAAGAACTG GGCGCCAGGT 
GAACCAAACA ACAAACAAAG AAACGAGGAC TGTGTAGAGA TCTACATCCA AAGACCCAAA 
GACTCCGGCA TGTGGAATGA CGAGAGATGT GACAAAAAGA AACTGGCTCT GTGTTACACA 
GCTTCCTGTA CCAACACATC CTGCAGTGGT CACGGTGAAT GCGTTGAGAC CATCAATAGT 
TATACCTGCA AATGTCACCC CGGCTTCCTG GGACCCAAGT GTGACCAAGT TGTGACCTGC 
CAAGAACAGG AATACCCTGA CCATGGAAGC CTGAACTGCA CCCACCCATT CGGCCTCTTC 
AGCTATAATT CATCCTGCTC CTTCAGCTGT GAAAGGGGCT ATGTGCCCAG CAGCATGGAG 
ACCACAGTGC GGTGTACGTC CTCTGGAGAG TGGAGTGCAC CTGCTCCTGC CTGCCATGTG 
GTTGAATGTA AAGCTTTGAC CCAACCTGCC CACGGAGTCA GGAAATGTTC CTCAAATCCT 
GGGAGCTACC CATGGAATAC AACGTGCACG TTTGATTGTG AGGAAGGGTA CAGGAGAGTT 
GGAGCTCAGA ATCTACAGTG TACCTCATCC GGTGTCTGGG ACAACGAGAA GCCATCGTGC 
AAAGCTGTGA CCTGTGATGC CATCCCTCGG CCTCAGAATG GCTCTGTGAG CTGCAGCAAC 
TCAACGGCTG GAGCGCTTGC CTTTAAGTCT TCCTGTAATT TTACCTGTGA GCACAGTTTC 
ACATTGCAGG GCCCAGCCCA GGTTGAATGC AGTGCACAAG GGCAGTGGAC ACCACAAATC 
CCAGTGTGCA AAGCTTCCCA GTGTGAAGCC TTATCTGCAC CACAGCGAGG CCACATGAAA 
TGTCTTCCCA GTGCCTCTGC ACCCTTCCAA AGTGGGTCCA GTTGTAAGTT CTCCTGTGAC 
GAAGGATTTG AATTGAAGGG ATCAAGAAGG CTTCAGTGTG GTCCAAGAGG GGAGTGGGAC 
AGCGAAAAGC CCACATGTGC AGGGGTACAG TGTTCAAGCC TTGACCTTCC AGGAAAGATG 
AACATGAGTT GCAGTGGGCC AGCAGTTTTT GGCACGGTAT GTGAATTTAC ATGTCCTGAG 
GGTTGGACAC TCAACGGATC TTCAATCCTG ACATGTGGTG CCACAGGACG CTGGTCTGCG 
ATGCTGCCTA CTTGTGAAGC CCCAGCCAAC CCTCCCCGTC CCTTGGTAGT GGCACTCTCT 
GTGGCAGCAA CCTCACTTCT GACATTGTCC TCATTGATCT ACGTGTTGAA GAGATTCTTT 
TGGAAGAAAG CAAAGAAATT CGTTCCTGCT AGTAGCTGCC AAAGTCTTCA ATCGTTTGAA 
AACTATCAAG GGCCTTCTTA CATCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sele ( XM_008769608.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008767830.1 Rattus norvegicus selectin E (Sele), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa43141
Clone ID Related Accession (Same CDS sequence)	XM_008769608.2
Accession Version	XM_008769608.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E-selectin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769608.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGGAA GTGCTGGGGT CATGAATGCC TCGTGCTTTC TCTCTGCTCT CACCTTTGTT 
CTCCTCATTG GAAAGAGCAT AGCTTGGTAC TACAATGCCT CCAGTGAGCT CATGACATAT 
GATGAAGCAA GTGCGTATTG TCAACGGGAC TACACACATC TGGTGGCGAT TCAGAACAAG 
GAAGAGATCA ATTACCTAAA CTCCACTCTG AGGTATTCAC CAAGTTATTA CTGGATTGGA 
ATCAGAAAAG TCAATAATGT ATGGATCTGG GTGGGGACCC AGAAGCCTCT GACGGAGGAA 
GCTAAGAACT GGGCGCCAGG TGAACCAAAC AACAAACAAA GAAACGAGGA CTGTGTAGAG 
ATCTACATCC AAAGACCCAA AGACTCCGGC ATGTGGAATG ACGAGAGATG TGACAAAAAG 
AAACTGGCTC TGTGTTACAC AGCTTCCTGT ACCAACACAT CCTGCAGTGG TCACGGTGAA 
TGCGTTGAGA CCATCAATAG TTATACCTGC AAATGTCACC CCGGCTTCCT GGGACCCAAG 
TGTGACCAAG TTGTGACCTG CCAAGAACAG GAATACCCTG ACCATGGAAG CCTGAACTGC 
ACCCACCCAT TCGGCCTCTT CAGCTATAAT TCATCCTGCT CCTTCAGCTG TGAAAGGGGC 
TATGTGCCCA GCAGCATGGA GACCACAGTG CGGTGTACGT CCTCTGGAGA GTGGAGTGCA 
CCTGCTCCTG CCTGCCATGT GGTTGAATGT AAAGCTTTGA CCCAACCTGC CCACGGAGTC 
AGGAAATGTT CCTCAAATCC TGGGAGCTAC CCATGGAATA CAACGTGCAC GTTTGATTGT 
GAGGAAGGGT ACAGGAGAGT TGGAGCTCAG AATCTACAGT GTACCTCATC CGGTGTCTGG 
GACAACGAGA AGCCATCGTG CAAAGCTGTG ACCTGTGATG CCATCCCTCG GCCTCAGAAT 
GGCTCTGTGA GCTGCAGCAA CTCAACGGCT GGAGCGCTTG CCTTTAAGTC TTCCTGTAAT 
TTTACCTGTG AGCACAGTTT CACATTGCAG GGCCCAGCCC AGGTTGAATG CAGTGCACAA 
GGGCAGTGGA CACCACAAAT CCCAGTGTGC AAAGCTTCCC AGTGTGAAGC CTTATCTGCA 
CCACAGCGAG GCCACATGAA ATGTCTTCCC AGTGCCTCTG CACCCTTCCA AAGTGGGTCC 
AGTTGTAAGT TCTCCTGTGA CGAAGGATTT GAATTGAAGG GATCAAGAAG GCTTCAGTGT 
GGTCCAAGAG GGGAGTGGGA CAGCGAAAAG CCCACATGTG CAGCTGTGAG ATGTGATGCT 
GTCCCTTGGC CCCAGAATGG TTTCGCGGCG TGTGCTCATG CTAATACTGG AGCATTCACT 
TACAAGTCCT CATGCGCCTT TCAATGCAAC GAGGGCTTTA AATTGCATGG ATCAGCTCAA 
CTTGAGTGCA CATCCCAGGG GACGTGGACC CAGGAAGTTC CCTCCTGCCA AAGGGTACAG 
TGTTCAAGCC TTGACCTTCC AGGAAAGATG AACATGAGTT GCAGTGGGCC AGCAGTTTTT 
GGCACAGTAT GTGAATTTAC ATGTCCTGAG GGTTGGACAC TCAACGGATC TTCAATCCTG 
ACATGTGGTG CCACAGGACG CTGGTCTGCG ATGCTGCCTA CTTGTGAAGC CCCAGCCAAC 
CCTCCCCGTC CCTTGGTAGT GGCACTTTCT GTGGCAGCAA CCTCACTTCT GACATTGTCC 
TCATTGATCT ACGTGTTGAA GAGATTCTTT TGGAAGAAAG CAAAGAAATT CGTTCCTGCT 
AGTAGCTGCC AAAGTCTTCA ATCGTTTGAA AACTATCAAG GGCCTTCTTA CATCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008767830.1
CDS	357..2216
Translation	MKGSAGVMNASCFLSALTFVLLIGKSIAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLRYSPSYYWIGIRKVNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETINSYTCKCHPGFLGPKCDQVVTCQEQEYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAAVRCDAVPWPQNGFAACAHANTGAFTYKSSCAFQCNEGFKLHGSAQLECTSQGTWTQEVPSCQRVQCSSLDLPGKMNMSCSGPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRPLVVALSVAATSLLTLSSLIYVLKRFFWKKAKKFVPASSCQSLQSFENYQGPSYII

Target ORF information:

RefSeq Version	XM_008769608.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin E (Sele), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769608.2

ORF Insert Sequence:

ATGAAAGGAA GTGCTGGGGT CATGAATGCC TCGTGCTTTC TCTCTGCTCT CACCTTTGTT 
CTCCTCATTG GAAAGAGCAT AGCTTGGTAC TACAATGCCT CCAGTGAGCT CATGACATAT 
GATGAAGCAA GTGCGTATTG TCAACGGGAC TACACACATC TGGTGGCGAT TCAGAACAAG 
GAAGAGATCA ATTACCTAAA CTCCACTCTG AGGTATTCAC CAAGTTATTA CTGGATTGGA 
ATCAGAAAAG TCAATAATGT ATGGATCTGG GTGGGGACCC AGAAGCCTCT GACGGAGGAA 
GCTAAGAACT GGGCGCCAGG TGAACCAAAC AACAAACAAA GAAACGAGGA CTGTGTAGAG 
ATCTACATCC AAAGACCCAA AGACTCCGGC ATGTGGAATG ACGAGAGATG TGACAAAAAG 
AAACTGGCTC TGTGTTACAC AGCTTCCTGT ACCAACACAT CCTGCAGTGG TCACGGTGAA 
TGCGTTGAGA CCATCAATAG TTATACCTGC AAATGTCACC CCGGCTTCCT GGGACCCAAG 
TGTGACCAAG TTGTGACCTG CCAAGAACAG GAATACCCTG ACCATGGAAG CCTGAACTGC 
ACCCACCCAT TCGGCCTCTT CAGCTATAAT TCATCCTGCT CCTTCAGCTG TGAAAGGGGC 
TATGTGCCCA GCAGCATGGA GACCACAGTG CGGTGTACGT CCTCTGGAGA GTGGAGTGCA 
CCTGCTCCTG CCTGCCATGT GGTTGAATGT AAAGCTTTGA CCCAACCTGC CCACGGAGTC 
AGGAAATGTT CCTCAAATCC TGGGAGCTAC CCATGGAATA CAACGTGCAC GTTTGATTGT 
GAGGAAGGGT ACAGGAGAGT TGGAGCTCAG AATCTACAGT GTACCTCATC CGGTGTCTGG 
GACAACGAGA AGCCATCGTG CAAAGCTGTG ACCTGTGATG CCATCCCTCG GCCTCAGAAT 
GGCTCTGTGA GCTGCAGCAA CTCAACGGCT GGAGCGCTTG CCTTTAAGTC TTCCTGTAAT 
TTTACCTGTG AGCACAGTTT CACATTGCAG GGCCCAGCCC AGGTTGAATG CAGTGCACAA 
GGGCAGTGGA CACCACAAAT CCCAGTGTGC AAAGCTTCCC AGTGTGAAGC CTTATCTGCA 
CCACAGCGAG GCCACATGAA ATGTCTTCCC AGTGCCTCTG CACCCTTCCA AAGTGGGTCC 
AGTTGTAAGT TCTCCTGTGA CGAAGGATTT GAATTGAAGG GATCAAGAAG GCTTCAGTGT 
GGTCCAAGAG GGGAGTGGGA CAGCGAAAAG CCCACATGTG CAGCTGTGAG ATGTGATGCT 
GTCCCTTGGC CCCAGAATGG TTTCGCGGCG TGTGCTCATG CTAATACTGG AGCATTCACT 
TACAAGTCCT CATGCGCCTT TCAATGCAAC GAGGGCTTTA AATTGCATGG ATCAGCTCAA 
CTTGAGTGCA CATCCCAGGG GACGTGGACC CAGGAAGTTC CCTCCTGCCA AAGGGTACAG 
TGTTCAAGCC TTGACCTTCC AGGAAAGATG AACATGAGTT GCAGTGGGCC AGCAGTTTTT 
GGCACAGTAT GTGAATTTAC ATGTCCTGAG GGTTGGACAC TCAACGGATC TTCAATCCTG 
ACATGTGGTG CCACAGGACG CTGGTCTGCG ATGCTGCCTA CTTGTGAAGC CCCAGCCAAC 
CCTCCCCGTC CCTTGGTAGT GGCACTTTCT GTGGCAGCAA CCTCACTTCT GACATTGTCC 
TCATTGATCT ACGTGTTGAA GAGATTCTTT TGGAAGAAAG CAAAGAAATT CGTTCCTGCT 
AGTAGCTGCC AAAGTCTTCA ATCGTTTGAA AACTATCAAG GGCCTTCTTA CATCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sele ( XM_017598678.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454167.1 Rattus norvegicus selectin E (Sele), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58004
Clone ID Related Accession (Same CDS sequence)	XM_017598678.1
Accession Version	XM_017598678.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E-selectin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGGAA GTGCTGGGGT CATGAATGCC TCGTGCTTTC TCTCTGCTCT CACCTTTGTT 
CTCCTCATTG GAAAGAGCAT AGCTTGGTAC TACAATGCCT CCAGTGAGCT CATGACATAT 
GATGAAGCAA GTGCGTATTG TCAACGGGAC TACACACATC TGGTGGCGAT TCAGAACAAG 
GAAGAGATCA ATTACCTAAA CTCCACTCTG AGGTATTCAC CAAGTTATTA CTGGATTGGA 
ATCAGAAAAG TCAATAATGT ATGGATCTGG GTGGGGACCC AGAAGCCTCT GACGGAGGAA 
GCTAAGAACT GGGCGCCAGG TGAACCAAAC AACAAACAAA GAAACGAGGA CTGTGTAGAG 
ATCTACATCC AAAGACCCAA AGACTCCGGC ATGTGGAATG ACGAGAGATG TGACAAAAAG 
AAACTGGCTC TGTGTTACAC AGCTTCCTGT ACCAACACAT CCTGCAGTGG TCACGGTGAA 
TGCGTTGAGA CCATCAATAG TTATACCTGC AAATGTCACC CCGGCTTCCT GGGACCCAAG 
TGTGACCAAG TTGTGACCTG CCAAGAACAG GAATACCCTG ACCATGGAAG CCTGAACTGC 
ACCCACCCAT TCGGCCTCTT CAGCTATAAT TCATCCTGCT CCTTCAGCTG TGAAAGGGGC 
TATGTGCCCA GCAGCATGGA GACCACAGTG CGGTGTACGT CCTCTGGAGA GTGGAGTGCA 
CCTGCTCCTG CCTGCCATGT GGTTGAATGT AAAGCTTTGA CCCAACCTGC CCACGGAGTC 
AGGAAATGTT CCTCAAATCC TGGGAGCTAC CCATGGAATA CAACGTGCAC GTTTGATTGT 
GAGGAAGGGT ACAGGAGAGT TGGAGCTCAG AATCTACAGT GTACCTCATC CGGTGTCTGG 
GACAACGAGA AGCCATCGTG CAAAGCTGTG ACCTGTGATG CCATCCCTCG GCCTCAGAAT 
GGCTCTGTGA GCTGCAGCAA CTCAACGGCT GGAGCGCTTG CCTTTAAGTC TTCCTGTAAT 
TTTACCTGTG AGCACAGTTT CACATTGCAG GGCCCAGCCC AGGTTGAATG CAGTGCACAA 
GGGCAGTGGA CACCACAAAT CCCAGTGTGC AAAGCTTCCC AGTGTGAAGC CTTATCTGCA 
CCACAGCGAG GCCACATGAA ATGTCTTCCC AGTGCCTCTG CACCCTTCCA AAGTGGGTCC 
AGTTGTAAGT TCTCCTGTGA CGAAGGATTT GAATTGAAGG GATCAAGAAG GCTTCAGTGT 
GGTCCAAGAG GGGAGTGGGA CAGCGAAAAG CCCACATGTG CAGGGGTACA GTGTTCAAGC 
CTTGACCTTC CAGGAAAGAT GAACATGAGT TGCAGTGGGC CAGCAGTTTT TGGCACAGTA 
TGTGAATTTA CATGTCCTGA GGGTTGGACA CTCAACGGAT CTTCAATCCT GACATGTGGT 
GCCACAGGAC GCTGGTCTGC GATGCTGCCT ACTTGTGAAG CCCCAGCCAA CCCTCCCCGT 
CCCTTGGTAG TGGCACTTTC TGTGGCAGCA ACCTCACTTC TGACATTGTC CTCATTGATC 
TACGTGTTGA AGAGATTCTT TTGGAAGAAA GCAAAGAAAT TCGTTCCTGC TAGTAGCTGC 
CAAAGTCTTC AATCGTTTGA AAACTATCAA GGGCCTTCTT ACATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454167.1
CDS	355..2025
Translation	MKGSAGVMNASCFLSALTFVLLIGKSIAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLRYSPSYYWIGIRKVNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETINSYTCKCHPGFLGPKCDQVVTCQEQEYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAGVQCSSLDLPGKMNMSCSGPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRPLVVALSVAATSLLTLSSLIYVLKRFFWKKAKKFVPASSCQSLQSFENYQGPSYII

Target ORF information:

RefSeq Version	XM_017598678.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin E (Sele), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598678.1

ORF Insert Sequence:

ATGAAAGGAA GTGCTGGGGT CATGAATGCC TCGTGCTTTC TCTCTGCTCT CACCTTTGTT 
CTCCTCATTG GAAAGAGCAT AGCTTGGTAC TACAATGCCT CCAGTGAGCT CATGACATAT 
GATGAAGCAA GTGCGTATTG TCAACGGGAC TACACACATC TGGTGGCGAT TCAGAACAAG 
GAAGAGATCA ATTACCTAAA CTCCACTCTG AGGTATTCAC CAAGTTATTA CTGGATTGGA 
ATCAGAAAAG TCAATAATGT ATGGATCTGG GTGGGGACCC AGAAGCCTCT GACGGAGGAA 
GCTAAGAACT GGGCGCCAGG TGAACCAAAC AACAAACAAA GAAACGAGGA CTGTGTAGAG 
ATCTACATCC AAAGACCCAA AGACTCCGGC ATGTGGAATG ACGAGAGATG TGACAAAAAG 
AAACTGGCTC TGTGTTACAC AGCTTCCTGT ACCAACACAT CCTGCAGTGG TCACGGTGAA 
TGCGTTGAGA CCATCAATAG TTATACCTGC AAATGTCACC CCGGCTTCCT GGGACCCAAG 
TGTGACCAAG TTGTGACCTG CCAAGAACAG GAATACCCTG ACCATGGAAG CCTGAACTGC 
ACCCACCCAT TCGGCCTCTT CAGCTATAAT TCATCCTGCT CCTTCAGCTG TGAAAGGGGC 
TATGTGCCCA GCAGCATGGA GACCACAGTG CGGTGTACGT CCTCTGGAGA GTGGAGTGCA 
CCTGCTCCTG CCTGCCATGT GGTTGAATGT AAAGCTTTGA CCCAACCTGC CCACGGAGTC 
AGGAAATGTT CCTCAAATCC TGGGAGCTAC CCATGGAATA CAACGTGCAC GTTTGATTGT 
GAGGAAGGGT ACAGGAGAGT TGGAGCTCAG AATCTACAGT GTACCTCATC CGGTGTCTGG 
GACAACGAGA AGCCATCGTG CAAAGCTGTG ACCTGTGATG CCATCCCTCG GCCTCAGAAT 
GGCTCTGTGA GCTGCAGCAA CTCAACGGCT GGAGCGCTTG CCTTTAAGTC TTCCTGTAAT 
TTTACCTGTG AGCACAGTTT CACATTGCAG GGCCCAGCCC AGGTTGAATG CAGTGCACAA 
GGGCAGTGGA CACCACAAAT CCCAGTGTGC AAAGCTTCCC AGTGTGAAGC CTTATCTGCA 
CCACAGCGAG GCCACATGAA ATGTCTTCCC AGTGCCTCTG CACCCTTCCA AAGTGGGTCC 
AGTTGTAAGT TCTCCTGTGA CGAAGGATTT GAATTGAAGG GATCAAGAAG GCTTCAGTGT 
GGTCCAAGAG GGGAGTGGGA CAGCGAAAAG CCCACATGTG CAGGGGTACA GTGTTCAAGC 
CTTGACCTTC CAGGAAAGAT GAACATGAGT TGCAGTGGGC CAGCAGTTTT TGGCACAGTA 
TGTGAATTTA CATGTCCTGA GGGTTGGACA CTCAACGGAT CTTCAATCCT GACATGTGGT 
GCCACAGGAC GCTGGTCTGC GATGCTGCCT ACTTGTGAAG CCCCAGCCAA CCCTCCCCGT 
CCCTTGGTAG TGGCACTTTC TGTGGCAGCA ACCTCACTTC TGACATTGTC CTCATTGATC 
TACGTGTTGA AGAGATTCTT TTGGAAGAAA GCAAAGAAAT TCGTTCCTGC TAGTAGCTGC 
CAAAGTCTTC AATCGTTTGA AAACTATCAA GGGCCTTCTT ACATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.
The Journal of biological chemistry292(6)2510-2518(2017 02)
Mehta-D'souza P,Klopocki AG,Oganesyan V,Terzyan S,Mather T,Li Z,Panicker SR,Zhu C,McEver RP

Hypoxia inhibits pulmonary artery endothelial cell apoptosis via the e-selectin/biliverdin reductase pathway.
Microvascular research10644-56(2016 07)
Song S,Yi Z,Zhang M,Mao M,Fu L,Zhao X,Liu Z,Gao J,Cao W,Liu Y,Shi H,Zhu D

Testosterone decreases the expression of endometrial pinopode and L-selectin ligand (MECA-79) in adult female rats during uterine receptivity period.
International journal of clinical and experimental pathology7(5)1967-76(2014)
Mokhtar HM,Giribabu N,Muniandy S,Salleh N

Age-dependent modifications in vascular adhesion molecules and apoptosis after 48-h reperfusion in a rat global cerebral ischemia model.
Age (Dordrecht, Netherlands)36(5)9703(2014)
Anuncibay-Soto B,P?rez-Rodr?guez D,Llorente IL,Regueiro-Purri?os M,Gonzalo-Orden JM,Fern?ndez-L?pez A

Atypical antipsychotics such as risperidone, but not paliperidone, worsen vascular endothelial function via upregulation of adhesion molecules VCAM-1, ICAM-1, and E-selectin in diabetic rats.
Canadian journal of physiology and pharmacology91(12)1119-26(2013 Dec)
Aboul-Fotouh S,Elgayar N

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Sele cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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