The following Nrdc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nrdc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01580 | |
| Clone ID Related Accession (Same CDS sequence) | NM_012993.2 | |
| Accession Version | NM_012993.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3486bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-19 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | nardilysin precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L27124.1. On Aug 31, 2012 this sequence version replaced NM_012993.1. ##Evidence-Data-START## Transcript exon combination :: FQ218095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCTGAGGA GAGTCGCGGT TGCTGCAGTC TTTGCCACCG GGAGGAAGTT GCGGTGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_037125.1 |
| CDS | 64..3549 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_012993.2 |
1 | ATGCTGAGGA GAGTCGCGGT TGCTGCAGTC TTTGCCACCG GGAGGAAGTT GCGGTGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa28378 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006238499.3 | |
| Accession Version | XM_006238499.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3690bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | nardilysin isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238499.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCTGAGGA GAGTCGCGGT TGCTGCAGTC TTTGCCACCG GGAGGAAGTT GCGGTGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006238561.1 |
| CDS | 201..3890 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006238499.3 |
1 | ATGCTGAGGA GAGTCGCGGT TGCTGCAGTC TTTGCCACCG GGAGGAAGTT GCGGTGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of Nardilysin, a Mitochondrial Co-chaperone for ?-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. |
Critical roles of nardilysin in the maintenance of body temperature homoeostasis. |
Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases. |
Nardilysin facilitates complex formation between mitochondrial malate dehydrogenase and citrate synthase. |
Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family. |
