Cd80 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd80
Entrez Gene ID	25408
Full Name	Cd80 molecule
Synonyms	B7-1
General protein information	Preferred Names Cd80 molecule Names T-lymphocyte activation antigen CD80 CD80 antigen CD80-like Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q21
Summary	cell surface protein that is part of the immune response; may be involved in induction of experimental autoimmune anterior uveitis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006248365.3	XP_006248427.1	T-lymphocyte activation antigen CD80 isoform X1
NM_012926.1	NP_037058.1	T-lymphocyte activation antigen CD80
XM_017597884.1	XP_017453373.1	T-lymphocyte activation antigen CD80 isoform X1
XM_017597885.1	XP_017453374.1	T-lymphocyte activation antigen CD80 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CD80	XP_001163234.1
Mus musculus (house mouse)	Cd80	NP_033985.3
Canis lupus familiaris (dog)	CD80	NP_001003147.1
Rattus norvegicus (Norway rat)	Cd80	NP_037058.1
	CD80	NP_001036107.1
Bos taurus (cattle)	CD80	NP_001193368.1
Homo sapiens (human)	CD80	NP_005182.1

Gene Ontology
Bibliography

Related articles in PubMed

CD80 Regulates Th17 Cell Differentiation in Coxsackie Virus B3-Induced Acute Myocarditis.
Huang Y, Li Y, Wei B, Wu W, Gao X
Inflammation41(1)232-239(2018 Feb)

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines.
Roberts LL, Robinson CM
Immunology141(1)39-51(2014 Jan)

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Liang Y, Cucchetti M, Roncagalli R, Yokosuka T, Malzac A, Bertosio E, Imbert J, Nijman IJ, Suchanek M, Saito T, W?lfing C, Malissen B, Malissen M
Nature immunology14(8)858-66(2013 Aug)

Increased production of circulating soluble co-stimulatory molecules CTLA-4, CD28 and CD80 in patients with rheumatoid arthritis.
Cao J, Zou L, Luo P, Chen P, Zhang L
International immunopharmacology14(4)585-92(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Selective expression of B7-1 (CD80) is important and may serve as a guide for future therapies aimed at transplant tolerance.
Title: HLA-G-treated tolerogenic dendritic cells induce tolerogenic potential by increasing expression of B7-1 (CD80) molecules.

Blocking expression of B7.1 in donor spleens by antisense gene therapy represents a potential alloantigen-specific immunosuppressive strategy to inhibit acute rejection against splenic allografts.
Title: Gene transfer of antisense B7.1 attenuates acute rejection against splenic allografts in rats.

Upregulation of B7.1 with the downregulation of GLEPP1, Wilms' tumor gene (WT1), megalin, and vascular endothelial growth factor started early and persisted through the course of rimary glomerular disease.
Title: Early changes in gene expression that influence the course of primary glomerular disease.

Upregulation of B7-1 in induced Minimal change-like nephropathy.
Title: Overexpression of interleukin-13 induces minimal-change-like nephropathy in rats.

an inducible diabetes model in transgenic mice based on rat insulin promotor (RIP)-driven expression of CD80 (B7-1) on pancreatic beta cells.
Title: Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity.

The following Cd80 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd80 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01334	NM_012926.1 Latest version!	Rattus norvegicus Cd80 molecule (Cd80), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa34289	XM_006248365.3 Latest version!	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34289	XM_017597884.1 Latest version!	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34289	XM_017597885.1 Latest version!	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd80 ( NM_012926.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037058.1 Rattus norvegicus Cd80 molecule (Cd80), mRNA.

Price & Availability↑

CloneID	ORa01334
Clone ID Related Accession (Same CDS sequence)	NM_012926.1
Accession Version	NM_012926.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD80
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF010465.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF010465.1, U05593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMN02642667 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGAATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATT AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGT AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC CGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037058.1
CDS	8..973
Translation	MAYSCQLMQESPLLGFPRLRFIHLFVLLLVGLFQISSGIVGQVSKSVREKALLSCDYKFCSEEQSIHRIYWQKHDKMVLSVISGVPEVWPEYKNRTVYDIANNYSFSLLGLILSDRGTYTCVVQRYEGESYVVKHLTTVELSVRADFPTPNITESGNPSADIKRITCFASGGFPKPRLSWLENGRELNGINTTISQDPESELYTISSQLDFNTTYDHFIDCFIEYGDAHVSQNFTWVKPPEDPPDEKQTIPFAWAGSDAVKAIIIFFIAITVIAVIAAIAIIIFCITVKFRRCFRRRNEASRETNKNLYIGPVEAAAEQTV

Target ORF information:

RefSeq Version	NM_012926.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd80 molecule (Cd80), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012926.1

ORF Insert Sequence:

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGAATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATT AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGT AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC CGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd80 ( XM_006248365.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248427.1 Rattus norvegicus Cd80 molecule (Cd80), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34289
Clone ID Related Accession (Same CDS sequence)	XM_006248365.3 , XM_017597884.1 , XM_017597885.1
Accession Version	XM_006248365.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD80 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248365.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248427.1
CDS	848..1813
Translation	MAYSCQLMQESPLLGFPRLRFIHLFVLLLVGLFQISSGIVGQVSKSVREKALLSCDYKFCSEEQSIHRIYWQKHDKMVLSVISGVPEVWPEYKNRTVYDIANNYSFSLLGLILSDRGTYTCVVQRYEGGSYVVKHLTTVELSVRADFPTPNITESGNPSADIKRITCFASGGFPKPRLSWLENGRELNGINTTISQDPESELYTISSQLDFNTTYDHFIDCFIEYGDAHVSQNFTWEKPPEDPPDEKQTIPFAWAGSDAVKAIIIFFIAITVIAVIAAIAIIIFCITVKFRRCFRRRNEASRETNKNLYIGPVEAAAEQTV

Target ORF information:

RefSeq Version	XM_006248365.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248365.3

ORF Insert Sequence:

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd80 ( XM_017597884.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453373.1 Rattus norvegicus Cd80 molecule (Cd80), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa34289
Clone ID Related Accession (Same CDS sequence)	XM_006248365.3 , XM_017597884.1 , XM_017597885.1
Accession Version	XM_017597884.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD80 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453373.1
CDS	295..1260
Translation	MAYSCQLMQESPLLGFPRLRFIHLFVLLLVGLFQISSGIVGQVSKSVREKALLSCDYKFCSEEQSIHRIYWQKHDKMVLSVISGVPEVWPEYKNRTVYDIANNYSFSLLGLILSDRGTYTCVVQRYEGGSYVVKHLTTVELSVRADFPTPNITESGNPSADIKRITCFASGGFPKPRLSWLENGRELNGINTTISQDPESELYTISSQLDFNTTYDHFIDCFIEYGDAHVSQNFTWEKPPEDPPDEKQTIPFAWAGSDAVKAIIIFFIAITVIAVIAAIAIIIFCITVKFRRCFRRRNEASRETNKNLYIGPVEAAAEQTV

Target ORF information:

RefSeq Version	XM_017597884.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597884.1

ORF Insert Sequence:

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd80 ( XM_017597885.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453374.1 Rattus norvegicus Cd80 molecule (Cd80), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa34289
Clone ID Related Accession (Same CDS sequence)	XM_006248365.3 , XM_017597884.1 , XM_017597885.1
Accession Version	XM_017597885.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD80 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453374.1
CDS	280..1245
Translation	MAYSCQLMQESPLLGFPRLRFIHLFVLLLVGLFQISSGIVGQVSKSVREKALLSCDYKFCSEEQSIHRIYWQKHDKMVLSVISGVPEVWPEYKNRTVYDIANNYSFSLLGLILSDRGTYTCVVQRYEGGSYVVKHLTTVELSVRADFPTPNITESGNPSADIKRITCFASGGFPKPRLSWLENGRELNGINTTISQDPESELYTISSQLDFNTTYDHFIDCFIEYGDAHVSQNFTWEKPPEDPPDEKQTIPFAWAGSDAVKAIIIFFIAITVIAVIAAIAIIIFCITVKFRRCFRRRNEASRETNKNLYIGPVEAAAEQTV

Target ORF information:

RefSeq Version	XM_017597885.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Cd80 molecule (Cd80), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597885.1

ORF Insert Sequence:

ATGGCTTACA GTTGCCAGCT GATGCAGGAA TCACCACTCC TCGGGTTTCC ACGTCTCAGG 
TTCATTCATC TCTTTGTGCT GCTGCTGGTT GGTCTTTTCC AGATATCTTC AGGTATTGTC 
GGCCAAGTGT CCAAGTCGGT GAGAGAAAAG GCATTGCTGT CCTGTGATTA CAAATTTTGT 
TCTGAAGAGC AGTCCATACA CCGAATCTAC TGGCAAAAAC ATGACAAAAT GGTGCTCTCT 
GTCATCTCCG GGGTACCGGA AGTGTGGCCC GAGTACAAGA ACCGGACTGT ATACGACATC 
GCTAACAACT ACTCCTTTAG CCTCCTGGGC CTGATCCTTT CAGACAGGGG CACATACACC 
TGTGTCGTTC AAAGGTACGA AGGAGGATCG TACGTGGTGA AACACCTGAC CACCGTGGAG 
CTGTCTGTCA GAGCTGACTT CCCTACCCCC AACATAACTG AGTCTGGAAA TCCATCTGCT 
GACATAAAGA GGATTACCTG CTTTGCTTCC GGGGGTTTCC CAAAGCCTCG CCTCTCTTGG 
TTGGAAAATG GAAGAGAATT AAATGGCATC AATACAACAA TTTCCCAGGA TCCTGAATCT 
GAGCTGTACA CCATTAGTAG CCAACTAGAC TTCAACACGA CGTACGACCA CTTCATCGAT 
TGTTTCATTG AGTATGGAGA TGCTCACGTG TCACAGAACT TCACCTGGGA AAAACCCCCA 
GAAGACCCTC CTGATGAAAA GCAAACAATT CCGTTTGCCT GGGCAGGATC TGATGCAGTC 
AAAGCCATCA TCATCTTCTT CATCGCCATC ACCGTCATCG CCGTCATCGC CGCCATCGCC 
ATCATCATCT TCTGCATCAC TGTCAAATTC CGACGCTGCT TCAGAAGAAG AAATGAGGCA 
AGCAGAGAAA CAAACAAGAA CCTCTACATA GGGCCTGTGG AAGCAGCAGC TGAACAGACT 
GTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CD80 Regulates Th17 Cell Differentiation in Coxsackie Virus B3-Induced Acute Myocarditis.
Inflammation41(1)232-239(2018 Feb)
Huang Y,Li Y,Wei B,Wu W,Gao X

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines.
Immunology141(1)39-51(2014 Jan)
Roberts LL,Robinson CM

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Nature immunology14(8)858-66(2013 Aug)
Liang Y,Cucchetti M,Roncagalli R,Yokosuka T,Malzac A,Bertosio E,Imbert J,Nijman IJ,Suchanek M,Saito T,W?lfing C,Malissen B,Malissen M

Increased production of circulating soluble co-stimulatory molecules CTLA-4, CD28 and CD80 in patients with rheumatoid arthritis.
International immunopharmacology14(4)585-92(2012 Dec)
Cao J,Zou L,Luo P,Chen P,Zhang L

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Cd80 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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