Fgf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fgf1
Entrez Gene ID	25317
Full Name	fibroblast growth factor 1
Synonyms	FGF-1,HBGF-1,HBGF1
General protein information	Preferred Names fibroblast growth factor 1 Names fibroblast growth factor 1 Fibroblast growth factor 1 (heparin binding) aFGF acidic fibroblast growth factor fibroblast growth factor 1 (acidic) heparin-binding growth factor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18p11
Summary	may play a role in neurite outgrowth; may regulate cell differentiation in the nervous system; may act in synergy with fibronectin to enhance neuronal cell adhesion [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006254652.3	XP_006254714.1	fibroblast growth factor 1 isoform X1
XM_006254651.3	XP_006254713.1	fibroblast growth factor 1 isoform X1
NM_012846.1	NP_036978.1	fibroblast growth factor 1
XM_006254650.3	XP_006254712.1	fibroblast growth factor 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FGF1	NP_001244139.1
	FGF1	XP_001095895.1
Bos taurus (cattle)	FGF1	NP_776480.1
Mus musculus (house mouse)	Fgf1	NP_034327.1
Gallus gallus (chicken)	FGF1	NP_990511.1
Xenopus tropicalis (tropical clawed frog)	fgf1	NP_001136293.1
Pan troglodytes (chimpanzee)	FGF1	XP_001153487.1
Canis lupus familiaris (dog)	FGF1	XP_849274.1
Rattus norvegicus (Norway rat)	Fgf1	NP_036978.1

Gene Ontology
Bibliography

Related articles in PubMed

Fibroblast Growth Factor Type 1 (FGF1)-Overexpressed Adipose-Derived Mesenchaymal Stem Cells (AD-MSC
Ghazavi H, Hoseini SJ, Ebrahimzadeh-Bideskan A, Mashkani B, Mehri S, Ghorbani A, Sadri K, Mahdipour E, Ghasemi F, Forouzanfar F, Hoseini A, Pasdar AR, Sadeghnia HR, Ghayour-Mobarhan M
Stem cell reviews13(5)670-685(2017 Oct)

Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.
Huang Z, Tan Y, Gu J, Liu Y, Song L, Niu J, Zhao L, Srinivasan L, Lin Q, Deng J, Li Y, Conklin DJ, Neubert TA, Cai L, Li X, Mohammadi M
Cell reports20(7)1717-1728(2017 Aug)

Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response.
Chapman JR, Katsara O, Ruoff R, Morgenstern D, Nayak S, Basilico C, Ueberheide B, Kolupaeva V
Molecular & cellular proteomics : MCP16(6)1126-1137(2017 Jun)

Fibroblast growth factor-1 attenuates TGF-?1-induced lung fibrosis.
Shimbori C, Bellaye PS, Xia J, Gauldie J, Ask K, Ramos C, Becerril C, Pardo A, Selman M, Kolb M
The Journal of pathology240(2)197-210(2016 10)

FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities.
Delmas E, Jah N, Pirou C, Bouleau S, Le Floch N, Vayssi?re JL, Mignotte B, Renaud F
Cell death & disease7e2079(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FGF-1 may have preventative and therapeutic effects on TGF-beta1-driven pulmonary fibrosis via inhibiting myofibroblast differentiation, inducing AEC proliferation, regulating TGF-beta1 signalling by controlling TGFbetaR1 expression and degradation, and regulating FGFR1 expression.
Title: Fibroblast growth factor-1 attenuates TGF-?1-induced lung fibrosis.

Results show that phosphorylation does not regulate FGF1 neurotrophic activity but inhibits its anti-apoptotic activity after p53-dependent apoptosis induction, giving new insight into the poorly described FGF1 intracrine/nuclear pathway.
Title: FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities.

FGF1 is secreted during prolonged activation of cultured beta-cells and that endoplasmic reticulum stress acts upstream of FGF1 release.
Title: FGF1 Mediates Overnutrition-Induced Compensatory ?-Cell Differentiation.

Study presents a transcript profiling of remyelinated multiple sclerosis lesions and identified FGF1 as a promoter of remyelination
Title: Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination.

Fibroblast growth factor 1, which induces maturation and cell cycle exit in chondrocytes, triggers rapid accumulation of retinoblastoma-like 1 (p107)-PP2A/B55-alpha complexes coinciding with retinoblastoma-like 1 (p107) dephosphorylation.
Title: Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55? holoenzyme.

The following Fgf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01106	NM_012846.1 Latest version!	Rattus norvegicus fibroblast growth factor 1 (Fgf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa01106	XM_006254652.3 Latest version!	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa01106	XM_006254651.3 Latest version!	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa01106	XM_006254650.3 Latest version!	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fgf1 ( NM_012846.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036978.1 Rattus norvegicus fibroblast growth factor 1 (Fgf1), mRNA.

Price & Availability↑

CloneID	ORa01106
Clone ID Related Accession (Same CDS sequence)	XM_006254652.3 , XM_006254651.3 , NM_012846.1 , XM_006254650.3
Accession Version	NM_012846.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	fibroblast growth factor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X14232.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X14232.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036978.1
CDS	267..734
Translation	MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

Target ORF information:

RefSeq Version	NM_012846.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fibroblast growth factor 1 (Fgf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012846.1

ORF Insert Sequence:

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf1 ( XM_006254652.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254714.1 Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa01106
Clone ID Related Accession (Same CDS sequence)	XM_006254652.3 , XM_006254651.3 , NM_012846.1 , XM_006254650.3
Accession Version	XM_006254652.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	fibroblast growth factor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254652.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254714.1
CDS	542..1009
Translation	MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

Target ORF information:

RefSeq Version	XM_006254652.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254652.3

ORF Insert Sequence:

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf1 ( XM_006254651.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254713.1 Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa01106
Clone ID Related Accession (Same CDS sequence)	XM_006254652.3 , XM_006254651.3 , NM_012846.1 , XM_006254650.3
Accession Version	XM_006254651.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	fibroblast growth factor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254651.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254713.1
CDS	510..977
Translation	MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

Target ORF information:

RefSeq Version	XM_006254651.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254651.3

ORF Insert Sequence:

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgf1 ( XM_006254650.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254712.1 Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01106
Clone ID Related Accession (Same CDS sequence)	XM_006254652.3 , XM_006254651.3 , NM_012846.1 , XM_006254650.3
Accession Version	XM_006254650.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	fibroblast growth factor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254650.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254712.1
CDS	533..1000
Translation	MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

Target ORF information:

RefSeq Version	XM_006254650.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fibroblast growth factor 1 (Fgf1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254650.3

ORF Insert Sequence:

ATGGCCGAAG GGGAGATCAC AACCTTTGCA GCCCTGACCG AGAGGTTCAA TCTGCCTCTA 
GGGAACTACA AAAAACCCAA ACTGCTCTAC TGCAGCAACG GGGGCCACTT CTTGAGGATT 
CTTCCCGATG GCACCGTGGA TGGGACCAGG GACAGGAGCG ACCAGCACAT TCAGCTGCAG 
CTCAGTGCGG AAAGCGCGGG CGAAGTGTAT ATAAAGGGTA CAGAGACTGG CCAGTACTTG 
GCCATGGACA CCGAAGGGCT TTTATACGGC TCGCAGACAC CAAATGAAGA ATGCCTATTC 
CTGGAAAGGC TAGAAGAAAA CCATTATAAC ACTTACACAT CCAAGAAGCA CGCGGAGAAG 
AACTGGTTTG TGGGCCTCAA GAAGAACGGG AGTTGTAAGC GCGGTCCTCG GACTCACTAC 
GGCCAGAAAG CCATCTTGTT TCTCCCCCTC CCGGTATCTT CTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fibroblast Growth Factor Type 1 (FGF1)-Overexpressed Adipose-Derived Mesenchaymal Stem Cells (AD-MSC
Stem cell reviews13(5)670-685(2017 Oct)
Ghazavi H,Hoseini SJ,Ebrahimzadeh-Bideskan A,Mashkani B,Mehri S,Ghorbani A,Sadri K,Mahdipour E,Ghasemi F,Forouzanfar F,Hoseini A,Pasdar AR,Sadeghnia HR,Ghayour-Mobarhan M

Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.
Cell reports20(7)1717-1728(2017 Aug)
Huang Z,Tan Y,Gu J,Liu Y,Song L,Niu J,Zhao L,Srinivasan L,Lin Q,Deng J,Li Y,Conklin DJ,Neubert TA,Cai L,Li X,Mohammadi M

Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response.
Molecular & cellular proteomics : MCP16(6)1126-1137(2017 Jun)
Chapman JR,Katsara O,Ruoff R,Morgenstern D,Nayak S,Basilico C,Ueberheide B,Kolupaeva V

Fibroblast growth factor-1 attenuates TGF-?1-induced lung fibrosis.
The Journal of pathology240(2)197-210(2016 10)
Shimbori C,Bellaye PS,Xia J,Gauldie J,Ask K,Ramos C,Becerril C,Pardo A,Selman M,Kolb M

FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities.
Cell death & disease7e2079(2016 Feb)
Delmas E,Jah N,Pirou C,Bouleau S,Le Floch N,Vayssi?re JL,Mignotte B,Renaud F

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Fgf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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