Adcy6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adcy6
Entrez Gene ID	25289
Full Name	adenylate cyclase 6
Synonyms	AC6,ACVI,ADCYB
General protein information	Preferred Names adenylate cyclase 6 Names adenylate cyclase type 6 ATP pyrophosphate-lyase 6 adenylate cyclase type VI adenylyl cyclase 6 ca(2+)-inhibitable adenylyl cyclase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36
Summary	may play a role in intracellular signaling [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594669.1	XP_017450158.1	adenylate cyclase type 6 isoform X1
NM_012821.4	NP_036953.4	adenylate cyclase type 6 isoform 2
XM_017594670.1	XP_017450159.1	adenylate cyclase type 6 isoform X1
NM_001270785.1	NP_001257714.1	adenylate cyclase type 6 isoform 1

Pathways from BioSystems

Homologies

	ADCY6	XP_001102486.1
Rattus norvegicus (Norway rat)	Adcy6	NP_001257714.1
Bos taurus (cattle)	ADCY6	NP_001137349.1
Danio rerio (zebrafish)	adcy6b	XP_002666536.2
Xenopus tropicalis (tropical clawed frog)	adcy6	XP_002935166.2
Homo sapiens (human)	ADCY6	NP_056085.1
Pan troglodytes (chimpanzee)	ADCY6	XP_509033.3
Canis lupus familiaris (dog)	ADCY6	NP_001182076.1
Mus musculus (house mouse)	Adcy6	NP_031431.2

Gene Ontology
Bibliography

Related articles in PubMed

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats.
Sang?esa G, Shaligram S, Akther F, Roglans N, Laguna JC, Rahimian R, Alegret M
American journal of physiology. Heart and circulatory physiology312(2)H289-H304(2017 Feb)

Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform.
Emery AC, Liu XH, Xu W, Eiden MV, Eiden LE
Molecular pharmacology87(6)928-35(2015 Jun)

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(??) subunits in human embryonic kidney 293T cells.
Ehrlich AT, Furuyashiki T, Kitaoka S, Kakizuka A, Narumiya S
Molecular pharmacology84(3)476-86(2013 Sep)

Characterization of adenylyl cyclase isoforms in rat peripheral pulmonary arteries.
Jourdan KB, Mason NA, Long L, Philips PG, Wilkins MR, Morrell NW
American journal of physiology. Lung cellular and molecular physiology280(6)L1359-69(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

AC isoform, and not the others expressed in PC12 cells, may reside in a plasma membrane compartment that is uniquely accessible to the family B Gs-coupled GPCR PAC1.
Title: Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform.

Alteration of hormonal sensitivity of adenylyl cyclase in the brain of rats with prolonged streptozotocin diabetes.
Title: Alteration of hormonal sensitivity of adenylyl cyclase in the brain of rats with prolonged streptozotocin diabetes.

In primary hippocampal neurons and Neuro2A cells, elevated AC6 expression suppressed neurite outgrowth, whereas the downregulation or genetic removal of AC6 promoted neurite extension.
Title: Type VI adenylyl cyclase regulates neurite extension by binding to Snapin and Snap25.

AC6, but not the closely related AC5, plays a principal role in vasodilator signalling and regulation of the membrane potential in Vascular smooth muscle cells (VSMCs).
Title: Principal role of adenylyl cyclase 6 in K? channel regulation and vasodilator signalling in vascular smooth muscle cells.

Isoproterenol activation of ACs promoted filamin phosphorylation, whereas thrombin inhibition of AC6 reduced filamin phosphorylation within the membrane fraction
Title: Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity.

The following Adcy6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adcy6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa61902	XM_017594669.1 Latest version!	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
ORa61902	XM_017594670.1 Latest version!	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
ORa09786	NM_001270785.1 Latest version!	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
ORa43060	NM_012821.4 Latest version!	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adcy6 ( XM_017594669.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450158.1 Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61902
Clone ID Related Accession (Same CDS sequence)	XM_017594669.1 , XM_017594670.1
Accession Version	XM_017594669.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	adenylate cyclase type 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGGAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGCGTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGCCACCT ACGACAGCTC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CCGCACCCAC CTGCAGCTTC CCTGAGTACT TTGTCGGGAG TGTGCTGCTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTG TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450158.1
CDS	1291..4791
Translation	MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAARTRCPWQDEAFIRRAGPGRGVELGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLAQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVALLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCPVFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGSFFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPSDVTACHLRQLNYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMTFVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS

Target ORF information:

RefSeq Version	XM_017594669.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594669.1

ORF Insert Sequence:

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGGAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGCGTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGCCACCT ACGACAGCTC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CCGCACCCAC CTGCAGCTTC CCTGAGTACT TTGTCGGGAG TGTGCTGCTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTG TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcy6 ( XM_017594670.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450159.1 Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa61902
Clone ID Related Accession (Same CDS sequence)	XM_017594669.1 , XM_017594670.1
Accession Version	XM_017594670.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	adenylate cyclase type 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGGAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGCGTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGCCACCT ACGACAGCTC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CCGCACCCAC CTGCAGCTTC CCTGAGTACT TTGTCGGGAG TGTGCTGCTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTG TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450159.1
CDS	26..3526
Translation	MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAARTRCPWQDEAFIRRAGPGRGVELGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLAQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVALLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCPVFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGSFFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPSDVTACHLRQLNYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMTFVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS

Target ORF information:

RefSeq Version	XM_017594670.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594670.1

ORF Insert Sequence:

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGGAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGCGTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGCCACCT ACGACAGCTC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CCGCACCCAC CTGCAGCTTC CCTGAGTACT TTGTCGGGAG TGTGCTGCTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTG TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcy6 ( NM_001270785.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257714.1 Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 1, mRNA.

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CloneID	ORa09786
Clone ID Related Accession (Same CDS sequence)	NM_001270785.1
Accession Version	NM_001270785.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-30
Organism	Rattus norvegicus(Norway rat)
Product	adenylate cyclase type 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129405.5. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M96160.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCCCTGC CCGTGGCCCG ATCCGGTTCT GGGCGCAGCA GCATGTCATG GTTTAGCGGC 
CTCCTGGTTC CCAAAGTGGA TGAACGGAAA ACAGCCTGGG GCGAACGCAA TGGACAGAAG 
CGCCCACGCC AGGCGACCCG AGCCCGTGGC TTCTGCGCGC CCCGCTACAT GAGCTGCCTC 
AAGAATGTGG AGCCACCCAG CCCCACTCCT GCAGCTCGCA CTCGGTGCCC CTGGCAGGAT 
GAAGCCTTCA TCAGGAGGGC TGGCCCGGGA AGGGGTGTGG AGCTGGGGCT GCGGTCAGTG 
GCCTTGGGTT TTGATGACAC TGAGGTGACC ACACCGATGG GGACAGCTGA AGTGGCACCC 
GACACATCGC CTCGAAGCGG TCCGTCCTGC TGGCACCGGC TAGCGCAGGT GTTCCAGTCT 
AAGCAGTTCC GCTCCGCCAA GCTGGAGCGT CTGTACCAGC GGTACTTCTT CCAGATGAAC 
CAGAGCAGCC TCACGCTGCT CATGGCGGTG CTTGTGCTCC TCATGGCTGT ACTGTTGACC 
TTCCACGCCG CGCCTGCCCT GCCTCAGCCT GCTTATGTGG CCCTGCTGAC CTGTGCCTCC 
GTCCTTTTTG TGGTACTCAT GGTAGTGTGT AACCGACATA GCTTCCGCCA GGACTCCATG 
TGGGTAGTGA GCTATGTGGT TCTGGGCATC CTAGCAGCCG TGCAAGTCGG GGGTGCCCTG 
GCAGCCAACC CACGCAGCCC CTCAGCAGGC CTTTGGTGCC CCGTGTTCTT CGTCTACATC 
ACCTACACAC TTCTTCCCAT TCGTATGCGA GCGGCCGTGC TCAGTGGCCT GGGTCTTTCC 
ACCCTGCATT TGATTTTGGC CTGGCATCTC AACAATGGTG ACCCCTTCCT TTGGAAGCAG 
CTCGGTGCTA ACGTGGTGCT CTTCCTGTGC ACCAATGCCA TCGGTGTCTG CACGCACTAC 
CCCGCTGAAG TGTCTCAGCG CCAAGCCTTT CAGGAGACCC GTGGTTACAT CCAGGCCCGG 
CTGCACTTGC AGCATGAGAA TCGACAGCAG GAACGGCTGC TGCTGTCGGT GTTGCCCCAG 
CATGTTGCCA TGGAAATGAA AGAGGATATC AACACAAAAA AGGAAGACAT GATGTTCCAC 
AAGATTTACA TCCAGAAGCA TGACAATGTC AGCATCCTGT TTGCCGACAT CGAGGGCTTC 
ACCAGCCTGG CCTCCCAGTG CACTGCCCAG GAACTGGTCA TGACCTTGAA TGAGCTCTTT 
GCCCGGTTCG ACAAGCTGGC TGCGGAGAAT CACTGTCTGA GGATCAAGAT CTTAGGAGAC 
TGTTACTACT GTGTGTCGGG GCTGCCGGAG GCCCGGGCAG ACCATGCCCA CTGCTGTGTG 
GAGATGGGGG TAGACATGAT CGAGGCCATC TCGCTGGTGC GTGAGGTAAC GGGTGTAAAT 
GTGAACATGC GCGTGGGCAT CCACAGCGGG CGTGTACACT GCGGTGTCCT TGGTCTGCGG 
AAATGGCAGT TTGATGTCTG GTCCAACGAT GTGACCCTGG CCAACCACAT GGAGGCGGGG 
GGCCGGGCCG GCCGCATCCA CATCACTCGG GCCACACTGC AGTACCTGAA CGGGGACTAT 
GAGGTGGAGC CAGGCCGTGG CGGTGAGCGC AACGCGTACC TCAAGGAGCA GTGCATTGAG 
ACCTTCCTCA TACTAGGAGC CAGCCAGAAA CGGAAAGAGG AGAAGGCCAT GCTGGTCAAG 
CTGCAGCGGA CGCGGGCCAA CTCCATGGAA GGACTGATGC CCCGCTGGGT TCCTGACCGT 
GCCTTCTCCC GGACCAAGGA CTCTAAGGCA TTCCGACAGA TGGGCATCGA TGACTCTAGC 
AAAGAGAACC GGGGTGCCCA AGATGCTCTG AACCCTGAGG ATGAGGTGGA CGAGTTTCTG 
GGCCGAGCCA TCGATGCCCG AAGCATCGAC CAGCTGCGTA AGGACCATGT GCGCCGGTTC 
CTGCTCACCT TCCAGAGGGA GGATCTCGAG AAGAAGTATT CACGGAAAGT AGACCCTCGT 
TTCGGAGCCT ACGTCGCCTG TGCCCTCCTG GTTTTCTGCT TCATCTGTTT CATCCAGTTC 
CTCGTATTCC CACACTCCGC CCTGATACTC GGGATTTATG CCGGGATCTT CCTTTTGCTG 
CTGGTCACCG TGCTCATCTG TGCTGTGTGC TCCTGTGGGT CTTTCTTCCC CAACGCCCTG 
CAGCGCCTGT CCCGCAGTAT CGTCCGCTCA CGGGTGCACA GCACGGCTGT TGGAGTCTTC 
TCGGTTCTGC TTGTGTTCAT CTCTGCCATT GCCAACATGT TCACCTGCAG TCACACCCCA 
CTGAGGACCT GTGCGGCCCG GATGCTGAAC TTAACACCGT CCGATGTCAC CGCCTGCCAC 
CTACGACAGC TCAATTACTC TCTGGGACTG GAAGCTCCCC TGTGTGAGGG CACCGCACCC 
ACCTGCAGCT TCCCTGAGTA CTTTGTCGGG AGTGTGCTGC TGAGTCTCTT GGCCAGCTCC 
GTCTTCCTCC ACATCAGCAG CATTGGCAAG CTAGTTATGA CCTTTGTCTT GGGGTTCATC 
TACTTGCTTC TGCTTTTGCT GGGTCCCCCA GCCACCATCT TTGACAACTA TGATCTACTG 
CTTAGCGTCC ATGGCTTGGC TTCCTCCAAT GAGACCTTCG ATGGGCTGGA CTGCCCAGCC 
GTAGGGAGGG TAGCGCTCAA ATACATGACC CCTGTGATTC TCCTCGTGTT CGCCCTGGCA 
CTGTATCTAC ACGCACAACA GGTGGAATCT ACCGCCCGCC TGGACTTCCT GTGGAAACTG 
CAGGCCACAG GGGAGAAGGA GGAGATGGAG GAGTTGCAGG CCTACAACCG GCGGCTGCTG 
CATAACATCC TTCCCAAGGA CGTGGCTGCC CACTTCCTGG CCCGGGAGCG CCGCAACGAC 
GAGCTGTACT ACCAATCCTG CGAGTGCGTG GCTGTCATGT TTGCCTCCAT CGCCAACTTC 
TCTGAGTTCT ATGTGGAACT GGAGGCGAAC AATGAGGGCG TGGAGTGCCT GCGACTGCTC 
AATGAGATCA TCGCGGACTT TGATGAGATC ATCAGTGAGG AGAGGTTCCG GCAGCTGGAG 
AAGATCAAGA CCATCGGTAG CACTTACATG GCCGCCTCCG GGCTAAATGC CAGCACCTAT 
GACCAGGTCG GCCGCTCGCA CATCACCGCC CTGGCAGACT ACGCCATGCG GCTTATGGAG 
CAAATGAAAC ACATCAACGA ACACTCTTTC AACAACTTCC AGATGAAGAT CGGGTTGAAC 
ATGGGTCCGG TTGTAGCAGG TGTCATTGGG GCCCGGAAGC CACAGTATGA CATCTGGGGA 
AACACGGTGA ATGTTTCCAG CCGTATGGAC AGCACAGGAG TTCCTGACCG AATACAGGTG 
ACCACGGATC TGTACCAGGT TCTAGCTGCC AAGGGCTACC AACTGGAGTG TCGAGGGGTG 
GTCAAGGTGA AGGGAAAGGG GGAGATGACC ACCTACTTCC TCAATGGGGG CCCCAGCAGT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257714.1
CDS	14..3556
Translation	MPLPVARSGSGRSSMSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAARTRCPWQDEAFIRRAGPGRGVELGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLAQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVALLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCPVFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGSFFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPSDVTACHLRQLNYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMTFVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS

Target ORF information:

RefSeq Version	NM_001270785.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270785.1

ORF Insert Sequence:

ATGCCCCTGC CCGTGGCCCG ATCCGGTTCT GGGCGCAGCA GCATGTCATG GTTTAGCGGC 
CTCCTGGTTC CCAAAGTGGA TGAACGGAAA ACAGCCTGGG GCGAACGCAA TGGACAGAAG 
CGCCCACGCC AGGCGACCCG AGCCCGTGGC TTCTGCGCGC CCCGCTACAT GAGCTGCCTC 
AAGAATGTGG AGCCACCCAG CCCCACTCCT GCAGCTCGCA CTCGGTGCCC CTGGCAGGAT 
GAAGCCTTCA TCAGGAGGGC TGGCCCGGGA AGGGGTGTGG AGCTGGGGCT GCGGTCAGTG 
GCCTTGGGTT TTGATGACAC TGAGGTGACC ACACCGATGG GGACAGCTGA AGTGGCACCC 
GACACATCGC CTCGAAGCGG TCCGTCCTGC TGGCACCGGC TAGCGCAGGT GTTCCAGTCT 
AAGCAGTTCC GCTCCGCCAA GCTGGAGCGT CTGTACCAGC GGTACTTCTT CCAGATGAAC 
CAGAGCAGCC TCACGCTGCT CATGGCGGTG CTTGTGCTCC TCATGGCTGT ACTGTTGACC 
TTCCACGCCG CGCCTGCCCT GCCTCAGCCT GCTTATGTGG CCCTGCTGAC CTGTGCCTCC 
GTCCTTTTTG TGGTACTCAT GGTAGTGTGT AACCGACATA GCTTCCGCCA GGACTCCATG 
TGGGTAGTGA GCTATGTGGT TCTGGGCATC CTAGCAGCCG TGCAAGTCGG GGGTGCCCTG 
GCAGCCAACC CACGCAGCCC CTCAGCAGGC CTTTGGTGCC CCGTGTTCTT CGTCTACATC 
ACCTACACAC TTCTTCCCAT TCGTATGCGA GCGGCCGTGC TCAGTGGCCT GGGTCTTTCC 
ACCCTGCATT TGATTTTGGC CTGGCATCTC AACAATGGTG ACCCCTTCCT TTGGAAGCAG 
CTCGGTGCTA ACGTGGTGCT CTTCCTGTGC ACCAATGCCA TCGGTGTCTG CACGCACTAC 
CCCGCTGAAG TGTCTCAGCG CCAAGCCTTT CAGGAGACCC GTGGTTACAT CCAGGCCCGG 
CTGCACTTGC AGCATGAGAA TCGACAGCAG GAACGGCTGC TGCTGTCGGT GTTGCCCCAG 
CATGTTGCCA TGGAAATGAA AGAGGATATC AACACAAAAA AGGAAGACAT GATGTTCCAC 
AAGATTTACA TCCAGAAGCA TGACAATGTC AGCATCCTGT TTGCCGACAT CGAGGGCTTC 
ACCAGCCTGG CCTCCCAGTG CACTGCCCAG GAACTGGTCA TGACCTTGAA TGAGCTCTTT 
GCCCGGTTCG ACAAGCTGGC TGCGGAGAAT CACTGTCTGA GGATCAAGAT CTTAGGAGAC 
TGTTACTACT GTGTGTCGGG GCTGCCGGAG GCCCGGGCAG ACCATGCCCA CTGCTGTGTG 
GAGATGGGGG TAGACATGAT CGAGGCCATC TCGCTGGTGC GTGAGGTAAC GGGTGTAAAT 
GTGAACATGC GCGTGGGCAT CCACAGCGGG CGTGTACACT GCGGTGTCCT TGGTCTGCGG 
AAATGGCAGT TTGATGTCTG GTCCAACGAT GTGACCCTGG CCAACCACAT GGAGGCGGGG 
GGCCGGGCCG GCCGCATCCA CATCACTCGG GCCACACTGC AGTACCTGAA CGGGGACTAT 
GAGGTGGAGC CAGGCCGTGG CGGTGAGCGC AACGCGTACC TCAAGGAGCA GTGCATTGAG 
ACCTTCCTCA TACTAGGAGC CAGCCAGAAA CGGAAAGAGG AGAAGGCCAT GCTGGTCAAG 
CTGCAGCGGA CGCGGGCCAA CTCCATGGAA GGACTGATGC CCCGCTGGGT TCCTGACCGT 
GCCTTCTCCC GGACCAAGGA CTCTAAGGCA TTCCGACAGA TGGGCATCGA TGACTCTAGC 
AAAGAGAACC GGGGTGCCCA AGATGCTCTG AACCCTGAGG ATGAGGTGGA CGAGTTTCTG 
GGCCGAGCCA TCGATGCCCG AAGCATCGAC CAGCTGCGTA AGGACCATGT GCGCCGGTTC 
CTGCTCACCT TCCAGAGGGA GGATCTCGAG AAGAAGTATT CACGGAAAGT AGACCCTCGT 
TTCGGAGCCT ACGTCGCCTG TGCCCTCCTG GTTTTCTGCT TCATCTGTTT CATCCAGTTC 
CTCGTATTCC CACACTCCGC CCTGATACTC GGGATTTATG CCGGGATCTT CCTTTTGCTG 
CTGGTCACCG TGCTCATCTG TGCTGTGTGC TCCTGTGGGT CTTTCTTCCC CAACGCCCTG 
CAGCGCCTGT CCCGCAGTAT CGTCCGCTCA CGGGTGCACA GCACGGCTGT TGGAGTCTTC 
TCGGTTCTGC TTGTGTTCAT CTCTGCCATT GCCAACATGT TCACCTGCAG TCACACCCCA 
CTGAGGACCT GTGCGGCCCG GATGCTGAAC TTAACACCGT CCGATGTCAC CGCCTGCCAC 
CTACGACAGC TCAATTACTC TCTGGGACTG GAAGCTCCCC TGTGTGAGGG CACCGCACCC 
ACCTGCAGCT TCCCTGAGTA CTTTGTCGGG AGTGTGCTGC TGAGTCTCTT GGCCAGCTCC 
GTCTTCCTCC ACATCAGCAG CATTGGCAAG CTAGTTATGA CCTTTGTCTT GGGGTTCATC 
TACTTGCTTC TGCTTTTGCT GGGTCCCCCA GCCACCATCT TTGACAACTA TGATCTACTG 
CTTAGCGTCC ATGGCTTGGC TTCCTCCAAT GAGACCTTCG ATGGGCTGGA CTGCCCAGCC 
GTAGGGAGGG TAGCGCTCAA ATACATGACC CCTGTGATTC TCCTCGTGTT CGCCCTGGCA 
CTGTATCTAC ACGCACAACA GGTGGAATCT ACCGCCCGCC TGGACTTCCT GTGGAAACTG 
CAGGCCACAG GGGAGAAGGA GGAGATGGAG GAGTTGCAGG CCTACAACCG GCGGCTGCTG 
CATAACATCC TTCCCAAGGA CGTGGCTGCC CACTTCCTGG CCCGGGAGCG CCGCAACGAC 
GAGCTGTACT ACCAATCCTG CGAGTGCGTG GCTGTCATGT TTGCCTCCAT CGCCAACTTC 
TCTGAGTTCT ATGTGGAACT GGAGGCGAAC AATGAGGGCG TGGAGTGCCT GCGACTGCTC 
AATGAGATCA TCGCGGACTT TGATGAGATC ATCAGTGAGG AGAGGTTCCG GCAGCTGGAG 
AAGATCAAGA CCATCGGTAG CACTTACATG GCCGCCTCCG GGCTAAATGC CAGCACCTAT 
GACCAGGTCG GCCGCTCGCA CATCACCGCC CTGGCAGACT ACGCCATGCG GCTTATGGAG 
CAAATGAAAC ACATCAACGA ACACTCTTTC AACAACTTCC AGATGAAGAT CGGGTTGAAC 
ATGGGTCCGG TTGTAGCAGG TGTCATTGGG GCCCGGAAGC CACAGTATGA CATCTGGGGA 
AACACGGTGA ATGTTTCCAG CCGTATGGAC AGCACAGGAG TTCCTGACCG AATACAGGTG 
ACCACGGATC TGTACCAGGT TCTAGCTGCC AAGGGCTACC AACTGGAGTG TCGAGGGGTG 
GTCAAGGTGA AGGGAAAGGG GGAGATGACC ACCTACTTCC TCAATGGGGG CCCCAGCAGT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcy6 ( NM_012821.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036953.4 Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 2, mRNA.

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CloneID	ORa43060
Clone ID Related Accession (Same CDS sequence)	NM_012821.4
Accession Version	NM_012821.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-30
Organism	Rattus norvegicus(Norway rat)
Product	adenylate cyclase type 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from L01115.1. On Oct 7, 2014 this sequence version replaced NM_012821.3. Transcript Variant: This variant (2) uses an alternate first exon in place of that of exon 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L01115.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGAAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGGCTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGTCACCT ACGACAGATC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CAGCACCCAC CTGCAGTTTC CCTGAGTACT TTGTCGGGAG TGTGCTGTTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTC TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036953.4
CDS	91..3591
Translation	MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAARTRCPWQDEAFIRRAGPGRGVKLGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLAQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVALLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCPVFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNGYLKEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGSFFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPSDVTACHLRQINYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMTFVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS

Target ORF information:

RefSeq Version	NM_012821.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase 6 (Adcy6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012821.4

ORF Insert Sequence:

ATGTCATGGT TTAGCGGCCT CCTGGTTCCC AAAGTGGATG AACGGAAAAC AGCCTGGGGC 
GAACGCAATG GACAGAAGCG CCCACGCCAG GCGACCCGAG CCCGTGGCTT CTGCGCGCCC 
CGCTACATGA GCTGCCTCAA GAATGTGGAG CCACCCAGCC CCACTCCTGC AGCTCGCACT 
CGGTGCCCCT GGCAGGATGA AGCCTTCATC AGGAGGGCTG GCCCGGGAAG GGGTGTGAAG 
CTGGGGCTGC GGTCAGTGGC CTTGGGTTTT GATGACACTG AGGTGACCAC ACCGATGGGG 
ACAGCTGAAG TGGCACCCGA CACATCGCCT CGAAGCGGTC CGTCCTGCTG GCACCGGCTA 
GCGCAGGTGT TCCAGTCTAA GCAGTTCCGC TCCGCCAAGC TGGAGCGTCT GTACCAGCGG 
TACTTCTTCC AGATGAACCA GAGCAGCCTC ACGCTGCTCA TGGCGGTGCT TGTGCTCCTC 
ATGGCTGTAC TGTTGACCTT CCACGCCGCG CCTGCCCTGC CTCAGCCTGC TTATGTGGCC 
CTGCTGACCT GTGCCTCCGT CCTTTTTGTG GTACTCATGG TAGTGTGTAA CCGACATAGC 
TTCCGCCAGG ACTCCATGTG GGTAGTGAGC TATGTGGTTC TGGGCATCCT AGCAGCCGTG 
CAAGTCGGGG GTGCCCTGGC AGCCAACCCA CGCAGCCCCT CAGCAGGCCT TTGGTGCCCC 
GTGTTCTTCG TCTACATCAC CTACACACTT CTTCCCATTC GTATGCGAGC GGCCGTGCTC 
AGTGGCCTGG GTCTTTCCAC CCTGCATTTG ATTTTGGCCT GGCATCTCAA CAATGGTGAC 
CCCTTCCTTT GGAAGCAGCT CGGTGCTAAC GTGGTGCTCT TCCTGTGCAC CAATGCCATC 
GGTGTCTGCA CGCACTACCC CGCTGAAGTG TCTCAGCGCC AAGCCTTTCA GGAGACCCGT 
GGTTACATCC AGGCCCGGCT GCACTTGCAG CATGAGAATC GACAGCAGGA ACGGCTGCTG 
CTGTCGGTGT TGCCCCAGCA TGTTGCCATG GAAATGAAAG AGGATATCAA CACAAAAAAG 
GAAGACATGA TGTTCCACAA GATTTACATC CAGAAGCATG ACAATGTCAG CATCCTGTTT 
GCCGACATCG AGGGCTTCAC CAGCCTGGCC TCCCAGTGCA CTGCCCAGGA ACTGGTCATG 
ACCTTGAATG AGCTCTTTGC CCGGTTCGAC AAGCTGGCTG CGGAGAATCA CTGTCTGAGG 
ATCAAGATCT TAGGAGACTG TTACTACTGT GTGTCGGGGC TGCCGGAGGC CCGGGCAGAC 
CATGCCCACT GCTGTGTGGA GATGGGGGTA GACATGATCG AGGCCATCTC GCTGGTGCGT 
GAGGTAACGG GTGTAAATGT GAACATGCGC GTGGGCATCC ACAGCGGGCG TGTACACTGC 
GGTGTCCTTG GTCTGCGGAA ATGGCAGTTT GATGTCTGGT CCAACGATGT GACCCTGGCC 
AACCACATGG AGGCGGGGGG CCGGGCCGGC CGCATCCACA TCACTCGGGC CACACTGCAG 
TACCTGAACG GGGACTATGA GGTGGAGCCA GGCCGTGGCG GTGAGCGCAA CGGCTACCTC 
AAGGAGCAGT GCATTGAGAC CTTCCTCATA CTAGGAGCCA GCCAGAAACG GAAAGAGGAG 
AAGGCCATGC TGGTCAAGCT GCAGCGGACG CGGGCCAACT CCATGGAAGG ACTGATGCCC 
CGCTGGGTTC CTGACCGTGC CTTCTCCCGG ACCAAGGACT CTAAGGCATT CCGACAGATG 
GGCATCGATG ACTCTAGCAA AGAGAACCGG GGTGCCCAAG ATGCTCTGAA CCCTGAGGAT 
GAGGTGGACG AGTTTCTGGG CCGAGCCATC GATGCCCGAA GCATCGACCA GCTGCGTAAG 
GACCATGTGC GCCGGTTCCT GCTCACCTTC CAGAGGGAGG ATCTCGAGAA GAAGTATTCA 
CGGAAAGTAG ACCCTCGTTT CGGAGCCTAC GTCGCCTGTG CCCTCCTGGT TTTCTGCTTC 
ATCTGTTTCA TCCAGTTCCT CGTATTCCCA CACTCCGCCC TGATACTCGG GATTTATGCC 
GGGATCTTCC TTTTGCTGCT GGTCACCGTG CTCATCTGTG CTGTGTGCTC CTGTGGGTCT 
TTCTTCCCCA ACGCCCTGCA GCGCCTGTCC CGCAGTATCG TCCGCTCACG GGTGCACAGC 
ACGGCTGTTG GAGTCTTCTC GGTTCTGCTT GTGTTCATCT CTGCCATTGC CAACATGTTC 
ACCTGCAGTC ACACCCCACT GAGGACCTGT GCGGCCCGGA TGCTGAACTT AACACCGTCC 
GATGTCACCG CCTGTCACCT ACGACAGATC AATTACTCTC TGGGACTGGA AGCTCCCCTG 
TGTGAGGGCA CAGCACCCAC CTGCAGTTTC CCTGAGTACT TTGTCGGGAG TGTGCTGTTG 
AGTCTCTTGG CCAGCTCCGT CTTCCTCCAC ATCAGCAGCA TTGGCAAGCT AGTTATGACC 
TTTGTCTTGG GGTTCATCTA CTTGCTTCTG CTTTTGCTGG GTCCCCCAGC CACCATCTTT 
GACAACTATG ATCTACTGCT TAGCGTCCAT GGCTTGGCTT CCTCCAATGA GACCTTCGAT 
GGGCTGGACT GCCCAGCCGT AGGGAGGGTA GCGCTCAAAT ACATGACCCC TGTGATTCTC 
CTCGTGTTCG CCCTGGCACT GTATCTACAC GCACAACAGG TGGAATCTAC CGCCCGCCTG 
GACTTCCTGT GGAAACTGCA GGCCACAGGG GAGAAGGAGG AGATGGAGGA GTTGCAGGCC 
TACAACCGGC GGCTGCTGCA TAACATCCTT CCCAAGGACG TGGCTGCCCA CTTCCTGGCC 
CGGGAGCGCC GCAACGACGA GCTGTACTAC CAATCCTGCG AGTGCGTGGC TGTCATGTTT 
GCCTCCATCG CCAACTTCTC TGAGTTCTAT GTGGAACTGG AGGCGAACAA TGAGGGCGTG 
GAGTGCCTGC GACTGCTCAA TGAGATCATC GCGGACTTTG ATGAGATCAT CAGTGAGGAG 
AGGTTCCGGC AGCTGGAGAA GATCAAGACC ATCGGTAGCA CTTACATGGC CGCCTCCGGG 
CTAAATGCCA GCACCTATGA CCAGGTCGGC CGCTCGCACA TCACCGCCCT GGCAGACTAC 
GCCATGCGGC TTATGGAGCA AATGAAACAC ATCAACGAAC ACTCTTTCAA CAACTTCCAG 
ATGAAGATCG GGTTGAACAT GGGTCCGGTT GTAGCAGGTG TCATTGGGGC CCGGAAGCCA 
CAGTATGACA TCTGGGGAAA CACGGTGAAT GTTTCCAGCC GTATGGACAG CACAGGAGTT 
CCTGACCGAA TACAGGTGAC CACGGATCTC TACCAGGTTC TAGCTGCCAA GGGCTACCAA 
CTGGAGTGTC GAGGGGTGGT CAAGGTGAAG GGAAAGGGGG AGATGACCAC CTACTTCCTC 
AATGGGGGCC CCAGCAGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats.
American journal of physiology. Heart and circulatory physiology312(2)H289-H304(2017 Feb)
Sang?esa G,Shaligram S,Akther F,Roglans N,Laguna JC,Rahimian R,Alegret M

Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform.
Molecular pharmacology87(6)928-35(2015 Jun)
Emery AC,Liu XH,Xu W,Eiden MV,Eiden LE

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(??) subunits in human embryonic kidney 293T cells.
Molecular pharmacology84(3)476-86(2013 Sep)
Ehrlich AT,Furuyashiki T,Kitaoka S,Kakizuka A,Narumiya S

Characterization of adenylyl cyclase isoforms in rat peripheral pulmonary arteries.
American journal of physiology. Lung cellular and molecular physiology280(6)L1359-69(2001 Jun)
Jourdan KB,Mason NA,Long L,Philips PG,Wilkins MR,Morrell NW

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Adcy6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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