Sfpq cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sfpq
Entrez Gene ID	252855
Full Name	splicing factor proline and glutamine rich
General protein information	Preferred Names splicing factor proline and glutamine rich Names splicing factor, proline- and glutamine-rich NonO/p54nrb homolog splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) splicing factor proline/glutamine-rich
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	FGF-induced protein related to a family of RNA- and DNA-binding proteins [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025271.1	NP_001020442.1	splicing factor, proline- and glutamine-rich

Pathways from BioSystems

Homologies

Homo sapiens (human)	SFPQ	NP_005057.1
Pan troglodytes (chimpanzee)	SFPQ	NP_001238776.1
Mus musculus (house mouse)	Sfpq	NP_076092.1
Bos taurus (cattle)	SFPQ	NP_001193220.1
Gallus gallus (chicken)	SFPQ	XP_417784.3
Danio rerio (zebrafish)	sfpq	NP_998443.1
Rattus norvegicus (Norway rat)	Sfpq	NP_001020442.1
Canis lupus familiaris (dog)	SFPQ	XP_005629463.1

Gene Ontology
Bibliography

Related articles in PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Morchikh M, Cribier A, Raffel R, Amraoui S, Cau J, Severac D, Dubois E, Schwartz O, Bennasser Y, Benkirane M
Molecular cell67(3)387-399.e5(2017 Aug)

The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Lee M, Sadowska A, Bekere I, Ho D, Gully BS, Lu Y, Iyer KS, Trewhella J, Fox AH, Bond CS
Nucleic acids research43(7)3826-40(2015 Apr)

Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Sury MD, McShane E, Hernandez-Miranda LR, Birchmeier C, Selbach M
Molecular & cellular proteomics : MCP14(1)50-65(2015 Jan)

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Zanivan S, Maione F, Hein MY, Hern?ndez-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)

Distinct roles of DBHS family members in the circadian transcriptional feedback loop.
Kowalska E, Ripperger JA, Muheim C, Maier B, Kurihara Y, Fox AH, Kramer A, Brown SA
Molecular and cellular biology32(22)4585-94(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Quantitative proteomics reveals dynamic interaction of JNK with RNA transport granule proteins Sfpq and Nono during neuronal differentiation
Title: Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.

Decreased PSF at term may result in a de-repression of progesterone receptor transcriptional control of contraction associated protein genes and thereby contributes to a functional withdrawal of progesterone at term labor.
Title: Expression and function of myometrial PSF suggest a role in progesterone withdrawal and the initiation of labor.

NONO and SFPQ were functionally involved in circadian Prl transcription since overexpression of both proteins greatly reduced Prl promoter activity (P<0.001) and disrupted its circadian pattern.
Title: Chromatin remodeling as a mechanism for circadian prolactin transcription: rhythmic NONO and SFPQ recruitment to HLTF.

The following Sfpq gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sfpq cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42155	NM_001025271.1 Latest version!	Rattus norvegicus splicing factor proline and glutamine rich (Sfpq), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sfpq ( NM_001025271.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020442.1 Rattus norvegicus splicing factor proline and glutamine rich (Sfpq), mRNA.

Price & Availability↑

CloneID	ORa42155
Clone ID Related Accession (Same CDS sequence)	NM_001025271.1
Accession Version	NM_001025271.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	splicing factor, proline- and glutamine-rich
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098731.1. On Jul 14, 2005 this sequence version replaced XM_342920.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC098731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCGGG ATCGGTTCCG GAGCCGCGGT GGTGGTGGTG GAGGCTTTCA TCGGCGTGGA 
GGAGGCGGTG GCCGCGGCGG CCTCCACGAC TTCCGCTCTC CGCCGCCTGG CATGGGCCTC 
AACCAGAATC GCGGCCCCAT GGGCCCCGGC CCTGGCGGCC CGAAGCCACC GCTCCCGCCT 
CCACCTCCGC ACCAGCAGCA GCAGCAACCT CCGCCGCAGC AGCCCCCGCC GCAGCAGCCT 
CCACCGCACC AGCAGCCGCC GCCACACCAG CCGCCCCATC AACAGCCCCC GCCTCCGCCG 
CAGGAATCCA AGCCCGTCGT CCCGCAAGGC CCCGGCTCGG CGCCCGGAGT GAGCACTGCG 
CCGCCTCCGG CGGTCTCGGC CCCGCCCGCC AACCCCCCTA CCACCGGCGC CCCGCCGGGC 
CCGGGTCCTA CCCCGACTCC GCCGCCCGCA GTCCCCTCTA CTGCCCCCGG ACCGCCTCCC 
CCTTCCACGC CGAGCAGCGG AGTCTCAACA ACGCCTCCAC AGACCGGTGG CCCTCCGCCA 
CCGCCCGCCG GGGGCGCCGG TCCAGGGCCT AAGCAAGGCC CAGGCCCTGG CGGTCCCAAA 
GGCGGCAAGA TGCCGGGTGG GCCTAAGCCT GGCGGTGGTC CGGGCATGGG CGCTCCTGGT 
GGCCACCCGA AGCCACCTCA CCGAGGTGGC GGGGAGCCCC GTGGGGGCCG GCAGCACCAC 
GCGCCCTACC ACCAGCAGCA CCATCAGGGC CCCCCTCCCG GCGGCCCGGG ACCTCGCACA 
GAGGAAAAGA TATCCGACTC GGAGGGATTT AAAGCCAACT TGTCTCTCTT GCGGAGGCCT 
GGAGAAAAAA CTTACACACA GCGCTGTCGG TTGTTTGTGG GGAACCTACC TGCTGATATC 
ACAGAGGATG AATTCAAAAG ACTGTTTGCT AAATACGGAG AACCGGGAGA AGTTTTTATC 
AACAAGGGCA AAGGGTTCGG GTTCATTAAA CTTGAGTCAA GAGCCTTGGC TGAAATTGCC 
AAAGCTGAAC TTGATGATAC CCCCATGAGA GGTAGACAGC TACGGGTTCG GTTTGCCACA 
CATGCTGCAG CCCTGTCTGT TCGGAATCTT TCTCCTTATG TATCCAATGA ACTTTTGGAA 
GAGGCCTTTA GCCAGTTTGG TCCTATTGAA AGGGCTGTTG TAATTGTGGA TGATCGTGGA 
AGATCCACGG GGAAAGGCAT TGTTGAATTT GCTTCGAAGC CAGCAGCAAG AAAAGCATTT 
GAAAGATGCA GTGAAGGTGT TTTCCTACTG ACAACGACTC CTCGCCCAGT CATTGTGGAA 
CCACTTGAGC AGTTAGATGA TGAAGATGGT CTTCCTGAAA AACTGGCCCA GAAGAATCCA 
ATGTATCAAA AGGAGAGAGA AACGCCTCCT CGTTTTGCTC AGCATGGCAC ATTTGAGTAT 
GAATATTCTC AACGATGGAA GTCTTTGGAT GAAATGGAAA AACAGCAAAG GGAACAAGTT 
GAAAAAAACA TGAAGGATGC AAAAGACAAG TTGGAAAGTG AAATGGAAGA TGCCTACCAT 
GAACACCAAG CAAATCTTTT GCGCCAAGAT CTGATGAGAC GCCAGGAAGA ATTAAGGCGC 
ATGGAGGAAC TTCACAGTCA AGAAATGCAG AAACGTAAAG AAATGCAGTT GAGGCAAGAG 
GAGGAACGGC GTAGAAGAGA GGAAGAGATG ATGATTCGCC AACGTGAGAT GGAAGAACAA 
ATGAGACGCC AACGAGAAGA AAGCTACAGC AGGATGGGCT ACATGGATCC AAGAGAAAGA 
GACATGAGAA TGGGTGGTGG TGGAACAATG AACATGGGAG ATCCCTATGG TTCAGGAGGC 
CAGAAATTTC CACCGCTAGG TGGTGGTGGT GGCATAGGTT ATGAAGCTAA TCCTGGAGTT 
CCACCAGCAA CCATGAGTGG TTCCATGATG GGAAGCGACA TGCGTACTGA GCGCTTTGGG 
CAGGGAGGTG CGGGTCCTGT GGGTGGACAG GGTCCTAGAG GAATGGGGCC TGGAACGCCA 
GCAGGATATG GTAGAGGGAG AGAAGAGTAT GAAGGGCCAA ATAAAAAACC CCGATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020442.1
CDS	74..2173
Translation	MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGGPKPPLPPPPPHQQQQQPPPQQPPPQQPPPHQQPPPHQPPHQQPPPPPQESKPVVPQGPGSAPGVSTAPPPAVSAPPANPPTTGAPPGPGPTPTPPPAVPSTAPGPPPPSTPSSGVSTTPPQTGGPPPPPAGGAGPGPKQGPGPGGPKGGKMPGGPKPGGGPGMGAPGGHPKPPHRGGGEPRGGRQHHAPYHQQHHQGPPPGGPGPRTEEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHSQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGTMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF

Target ORF information:

RefSeq Version	NM_001025271.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus splicing factor proline and glutamine rich (Sfpq), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025271.1

ORF Insert Sequence:

ATGTCTCGGG ATCGGTTCCG GAGCCGCGGT GGTGGTGGTG GAGGCTTTCA TCGGCGTGGA 
GGAGGCGGTG GCCGCGGCGG CCTCCACGAC TTCCGCTCTC CGCCGCCTGG CATGGGCCTC 
AACCAGAATC GCGGCCCCAT GGGCCCCGGC CCTGGCGGCC CGAAGCCACC GCTCCCGCCT 
CCACCTCCGC ACCAGCAGCA GCAGCAACCT CCGCCGCAGC AGCCCCCGCC GCAGCAGCCT 
CCACCGCACC AGCAGCCGCC GCCACACCAG CCGCCCCATC AACAGCCCCC GCCTCCGCCG 
CAGGAATCCA AGCCCGTCGT CCCGCAAGGC CCCGGCTCGG CGCCCGGAGT GAGCACTGCG 
CCGCCTCCGG CGGTCTCGGC CCCGCCCGCC AACCCCCCTA CCACCGGCGC CCCGCCGGGC 
CCGGGTCCTA CCCCGACTCC GCCGCCCGCA GTCCCCTCTA CTGCCCCCGG ACCGCCTCCC 
CCTTCCACGC CGAGCAGCGG AGTCTCAACA ACGCCTCCAC AGACCGGTGG CCCTCCGCCA 
CCGCCCGCCG GGGGCGCCGG TCCAGGGCCT AAGCAAGGCC CAGGCCCTGG CGGTCCCAAA 
GGCGGCAAGA TGCCGGGTGG GCCTAAGCCT GGCGGTGGTC CGGGCATGGG CGCTCCTGGT 
GGCCACCCGA AGCCACCTCA CCGAGGTGGC GGGGAGCCCC GTGGGGGCCG GCAGCACCAC 
GCGCCCTACC ACCAGCAGCA CCATCAGGGC CCCCCTCCCG GCGGCCCGGG ACCTCGCACA 
GAGGAAAAGA TATCCGACTC GGAGGGATTT AAAGCCAACT TGTCTCTCTT GCGGAGGCCT 
GGAGAAAAAA CTTACACACA GCGCTGTCGG TTGTTTGTGG GGAACCTACC TGCTGATATC 
ACAGAGGATG AATTCAAAAG ACTGTTTGCT AAATACGGAG AACCGGGAGA AGTTTTTATC 
AACAAGGGCA AAGGGTTCGG GTTCATTAAA CTTGAGTCAA GAGCCTTGGC TGAAATTGCC 
AAAGCTGAAC TTGATGATAC CCCCATGAGA GGTAGACAGC TACGGGTTCG GTTTGCCACA 
CATGCTGCAG CCCTGTCTGT TCGGAATCTT TCTCCTTATG TATCCAATGA ACTTTTGGAA 
GAGGCCTTTA GCCAGTTTGG TCCTATTGAA AGGGCTGTTG TAATTGTGGA TGATCGTGGA 
AGATCCACGG GGAAAGGCAT TGTTGAATTT GCTTCGAAGC CAGCAGCAAG AAAAGCATTT 
GAAAGATGCA GTGAAGGTGT TTTCCTACTG ACAACGACTC CTCGCCCAGT CATTGTGGAA 
CCACTTGAGC AGTTAGATGA TGAAGATGGT CTTCCTGAAA AACTGGCCCA GAAGAATCCA 
ATGTATCAAA AGGAGAGAGA AACGCCTCCT CGTTTTGCTC AGCATGGCAC ATTTGAGTAT 
GAATATTCTC AACGATGGAA GTCTTTGGAT GAAATGGAAA AACAGCAAAG GGAACAAGTT 
GAAAAAAACA TGAAGGATGC AAAAGACAAG TTGGAAAGTG AAATGGAAGA TGCCTACCAT 
GAACACCAAG CAAATCTTTT GCGCCAAGAT CTGATGAGAC GCCAGGAAGA ATTAAGGCGC 
ATGGAGGAAC TTCACAGTCA AGAAATGCAG AAACGTAAAG AAATGCAGTT GAGGCAAGAG 
GAGGAACGGC GTAGAAGAGA GGAAGAGATG ATGATTCGCC AACGTGAGAT GGAAGAACAA 
ATGAGACGCC AACGAGAAGA AAGCTACAGC AGGATGGGCT ACATGGATCC AAGAGAAAGA 
GACATGAGAA TGGGTGGTGG TGGAACAATG AACATGGGAG ATCCCTATGG TTCAGGAGGC 
CAGAAATTTC CACCGCTAGG TGGTGGTGGT GGCATAGGTT ATGAAGCTAA TCCTGGAGTT 
CCACCAGCAA CCATGAGTGG TTCCATGATG GGAAGCGACA TGCGTACTGA GCGCTTTGGG 
CAGGGAGGTG CGGGTCCTGT GGGTGGACAG GGTCCTAGAG GAATGGGGCC TGGAACGCCA 
GCAGGATATG GTAGAGGGAG AGAAGAGTAT GAAGGGCCAA ATAAAAAACC CCGATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Molecular cell67(3)387-399.e5(2017 Aug)
Morchikh M,Cribier A,Raffel R,Amraoui S,Cau J,Severac D,Dubois E,Schwartz O,Bennasser Y,Benkirane M

The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic acids research43(7)3826-40(2015 Apr)
Lee M,Sadowska A,Bekere I,Ho D,Gully BS,Lu Y,Iyer KS,Trewhella J,Fox AH,Bond CS

Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Molecular & cellular proteomics : MCP14(1)50-65(2015 Jan)
Sury MD,McShane E,Hernandez-Miranda LR,Birchmeier C,Selbach M

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)
Zanivan S,Maione F,Hein MY,Hern?ndez-Fernaud JR,Ostasiewicz P,Giraudo E,Mann M

Distinct roles of DBHS family members in the circadian transcriptional feedback loop.
Molecular and cellular biology32(22)4585-94(2012 Nov)
Kowalska E,Ripperger JA,Muheim C,Maier B,Kurihara Y,Fox AH,Kramer A,Brown SA

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Sfpq cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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