Dyrk1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dyrk1a
Entrez Gene ID	25255
Full Name	dual specificity tyrosine phosphorylation regulated kinase 1A
Synonyms	Dyrk,PSK47
General protein information	Preferred Names dual specificity tyrosine phosphorylation regulated kinase 1A Names dual specificity tyrosine-phosphorylation-regulated kinase 1A Dual Specificity Yak1-related kinase MNBH RP86 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A protein kinase minibrain homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q11
Summary	catalyzes the phosphorylation of dynamin 1 and regulates dynamin 1 interaction with amphiphysin 1; may regulate assembly of the endocytic apparatus [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008768563.2	XP_008766785.1	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1
XM_008768565.2	XP_008766787.1	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2
XM_008768564.1	XP_008766786.1	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1
NM_012791.3	NP_036923.1	dual specificity tyrosine-phosphorylation-regulated kinase 1A
XM_006248031.3	XP_006248093.1	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DYRK1A	NP_001387.2
	DYRK1A	XP_001083622.1
Gallus gallus (chicken)	DYRK1A	NP_989881.1
Rattus norvegicus (Norway rat)	Dyrk1a	NP_036923.1
Bos taurus (cattle)	DYRK1A	NP_001192943.1
Canis lupus familiaris (dog)	DYRK1A	XP_849580.2
Mus musculus (house mouse)	Dyrk1a	NP_001106860.1
Pan troglodytes (chimpanzee)	DYRK1A	XP_514894.2
Danio rerio (zebrafish)	dyrk1aa	NP_001074158.1
Xenopus tropicalis (tropical clawed frog)	dyrk1a	NP_001072280.1

Gene Ontology
Bibliography

Related articles in PubMed

Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Garc?a-Cerro S, Rueda N, Vidal V, Lantigua S, Mart?nez-Cu? C
Neurobiology of disease10676-88(2017 Oct)

Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice.
Yin X, Jin N, Shi J, Zhang Y, Wu Y, Gong CX, Iqbal K, Liu F
Scientific reports7(1)619(2017 Apr)

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.
Birling MC, Schaeffer L, Andr? P, Lindner L, Mar?chal D, Ayadi A, Sorg T, Pavlovic G, H?rault Y
Scientific reports743331(2017 Mar)

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.
Hille S, Dierck F, K?hl C, Sosna J, Adam-Klages S, Adam D, L?llmann-Rauch R, Frey N, Kuhn C
Cardiovascular research110(3)381-94(2016 06)

Involvement of the dual-specificity tyrosine phosphorylation-regulated kinase 1A-alternative splicing factor-calcium/calmodulin-dependent protein kinase II? signaling pathway in myocardial infarction-induced heart failure of rats.
He J, Yao J, Sheng H, Zhu J
Journal of cardiac failure21(9)751-60(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Identify Dyrk1a as a novel negative regulator of D-cyclin-mediated Rb1/E2f-signalling. As dysregulation of this pathway with impaired cardiomyocyte proliferation leads to cardiomyopathy.
Title: Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.

Enhanced activation of Dyrk1A-ASF-CaMKIIdelta signaling pathway may underlie the mechanisms of HF after MI, and Dyrk1A inhibition may contribute to inactivation of this pathway and thereby retard the progression of MI-induced HF.
Title: Involvement of the dual-specificity tyrosine phosphorylation-regulated kinase 1A-alternative splicing factor-calcium/calmodulin-dependent protein kinase II? signaling pathway in myocardial infarction-induced heart failure of rats.

A model of DYRK autoactivation has been proposed in which tyrosine autophosphorylation in the activation loop stabilizes a conformation of the catalytic domain with enhanced serine/threonine kinase activity without disabling tyrosine phosphorylation.
Title: Mechanism of dual specificity kinase activity of DYRK1A.

calcineurin/NFAT pathway mediates the upregulation of PAI-1 by NGF
Title: NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect.

Phosphorylation of SRp55 by Dyrk1A suppressed its ability to promote Tau exon 10 inclusion.
Title: Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion.

The following Dyrk1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00944	NM_012791.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa00944	XM_008768563.2 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa00944	XM_008768564.1 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa00944	XM_006248031.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa34131	XM_008768565.2 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dyrk1a ( NM_012791.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036923.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), mRNA.

Price & Availability↑

CloneID	ORa00944
Clone ID Related Accession (Same CDS sequence)	XM_008768563.2 , XM_008768564.1 , NM_012791.3 , XM_006248031.3
Accession Version	NM_012791.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106913.5 and AC131528.4. On Dec 13, 2016 this sequence version replaced NM_012791.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X79769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036923.1
CDS	128..2419
Translation	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS

Target ORF information:

RefSeq Version	NM_012791.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012791.3

ORF Insert Sequence:

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1a ( XM_008768563.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766785.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa00944
Clone ID Related Accession (Same CDS sequence)	XM_008768563.2 , XM_008768564.1 , NM_012791.3 , XM_006248031.3
Accession Version	XM_008768563.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768563.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766785.1
CDS	3210..5501
Translation	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS

Target ORF information:

RefSeq Version	XM_008768563.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768563.2

ORF Insert Sequence:

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1a ( XM_008768564.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766786.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa00944
Clone ID Related Accession (Same CDS sequence)	XM_008768563.2 , XM_008768564.1 , NM_012791.3 , XM_006248031.3
Accession Version	XM_008768564.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766786.1
CDS	175..2466
Translation	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS

Target ORF information:

RefSeq Version	XM_008768564.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768564.1

ORF Insert Sequence:

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1a ( XM_006248031.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248093.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa00944
Clone ID Related Accession (Same CDS sequence)	XM_008768563.2 , XM_008768564.1 , NM_012791.3 , XM_006248031.3
Accession Version	XM_006248031.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248031.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248093.1
CDS	3074..5365
Translation	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS

Target ORF information:

RefSeq Version	XM_006248031.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248031.3

ORF Insert Sequence:

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGGTG ATGCCTGACA TTGTCATGTT ACAGAGGCGG 
ATGCCCCAAA CCTTCCGTGA TCCAGCAACT GCTCCTCTGA GAAAACTCTC TGTGGACTTG 
ATCAAAACAT ACAAGCATAT TAATGAGGTT TACTATGCAA AAAAGAAGCG AAGACACCAA 
CAGGGCCAGG GGGACGATTC TAGTCATAAG AAGGAGCGGA AGGTTTACAA CGATGGTTAC 
GATGACGATA ACTATGATTA CATTGTAAAA AACGGAGAAA AGTGGATGGA CCGTTATGAA 
ATCGACTCCT TAATAGGCAA AGGTTCATTT GGACAGGTTG TGAAAGCATA TGACAGAGTG 
GAACAAGAAT GGGTCGCCAT TAAAATCATC AAGAACAAGA AGGCGTTTCT GAATCAAGCG 
CAGATAGAAG TGCGGCTGCT TGAGCTCATG AACAAACATG ACACTGAGAT GAAGTACTAC 
ATAGTGCATT TGAAACGCCA CTTTATGTTT CGGAACCATC TCTGTCTAGT GTTTGAAATG 
CTGTCCTATA ATCTCTATGA TTTGTTGAGG AACACCAACT TCCGAGGGGT CTCTTTGAAC 
CTGACACGAA AGTTTGCACA ACAGATGTGC ACAGCATTGC TTTTCCTTGC GACTCCAGAA 
CTTAGTATCA TTCACTGTGA CTTAAAGCCG GAGAACATCC TTCTGTGTAA CCCCAAACGA 
AGTGCAATCA AGATTGTTGA CTTTGGCAGC TCTTGTCAGT TGGGGCAGAG GATATACCAG 
TATATTCAGA GTCGCTTCTA TCGGTCTCCA GAGGTGCTAC TGGGAATGCC TTATGACCTT 
GCTATCGACA TGTGGTCCCT TGGATGTATC TTGGTTGAAA TGCACACTGG AGAGCCTCTG 
TTCAGTGGTG CCAATGAGGT GGATCAGATG AATAAAATAG TGGAAGTCTT GGGCATCCCA 
CCTGCTCATA TTCTTGACCA AGCACCGAAA GCAAGAAAGT TCTTTGAGAA GTTGCCTGAT 
GGCACTTGGA GCTTAAAGAA GACCAAAGAT GGAAAACGGG AGTACAAACC ACCAGGAACC 
CGTAAACTTC ATAATATTCT TGGAGTGGAA ACAGGAGGAC CTGGCGGGCG GCGTGCTGGG 
GAGTCAGGTC ACACTGTAGC TGACTACTTG AAGTTCAAAG ACCTCATTTT AAGGATGCTT 
GATTATGACC CCAAAACTCG GATTCAACCT TATTATGCCC TGCAGCACAG TTTTTTCAAG 
AAAACAGCTG ATGAAGGTAC AAACACAAGC AACAGTGTGT CCACCAGCCC TGCCATGGAG 
CAGTCCCAGT CTTCAGGCAC CACCTCCAGC ACCTCCTCCA GCTCAGGTGG ATCCTCGGGA 
ACGAGCAACA GTGGGAGAGC CAGGTCGGAT CCGACGCACC AGCATCGGCA CAGTGGCGGG 
CACTTCGCTG CTGCTGTCCA GGCCATGGAC TGTGAGACAC ATAGTCCCCA GGTGCGCCAG 
CAGTTTCCGG CTCCTCTGGG CTGGTCAGGC ACTGAAGCTC CTACACAAGT CACTGTTGAA 
ACTCATCCTG TTCAAGAAAC AACCTTTCAT GTAGCCCCTC AGCAGAATGC ATTGCATCAT 
CACCATGGAA ACAGTTCCCA TCATCACCAC CACCACCATC ACCACCACCA CCACCATGGA 
CAGCAAGCCT TGGGTAACCG GACCAGGCCA AGGGTCTACA ATTCTCCAAC AAATAGCTCC 
TCTACCCAGG ATTCTATGGA GGTTGGCCAC AGTCACCACT CCATGACATC CCTGTCTTCC 
TCAACAACTT CTTCCTCGAC ATCTTCCTCC TCTACTGGTA ATCAAGGCAA TCAGGCCTAT 
CAGAACCGCC CAGTGGCTGC TAACACCTTG GACTTTGGAC AGAATGGAGC TATGGACGTT 
AATTTGACCG TCTACTCCAA TCCCCGCCAA GAGACTGGCA TAGCTGGACA TCCAACATAC 
CAATTTTCTG CTAATACAGG TCCTGCACAT TACATGACTG AAGGACATCT GACGATGAGG 
CAAGGGGCTG ATAGAGAAGA GTCTCCCATG ACAGGAGTTT GTGTGCAACA GAGTCCTGTA 
GCTAGCTCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1a ( XM_008768565.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766787.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa34131
Clone ID Related Accession (Same CDS sequence)	XM_008768565.2
Accession Version	XM_008768565.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768565.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGAGG CGGATGCCCC AAACCTTCCG TGATCCAGCA 
ACTGCTCCTC TGAGAAAACT CTCTGTGGAC TTGATCAAAA CATACAAGCA TATTAATGAG 
GTTTACTATG CAAAAAAGAA GCGAAGACAC CAACAGGGCC AGGGGGACGA TTCTAGTCAT 
AAGAAGGAGC GGAAGGTTTA CAACGATGGT TACGATGACG ATAACTATGA TTACATTGTA 
AAAAACGGAG AAAAGTGGAT GGACCGTTAT GAAATCGACT CCTTAATAGG CAAAGGTTCA 
TTTGGACAGG TTGTGAAAGC ATATGACAGA GTGGAACAAG AATGGGTCGC CATTAAAATC 
ATCAAGAACA AGAAGGCGTT TCTGAATCAA GCGCAGATAG AAGTGCGGCT GCTTGAGCTC 
ATGAACAAAC ATGACACTGA GATGAAGTAC TACATAGTGC ATTTGAAACG CCACTTTATG 
TTTCGGAACC ATCTCTGTCT AGTGTTTGAA ATGCTGTCCT ATAATCTCTA TGATTTGTTG 
AGGAACACCA ACTTCCGAGG GGTCTCTTTG AACCTGACAC GAAAGTTTGC ACAACAGATG 
TGCACAGCAT TGCTTTTCCT TGCGACTCCA GAACTTAGTA TCATTCACTG TGACTTAAAG 
CCGGAGAACA TCCTTCTGTG TAACCCCAAA CGAAGTGCAA TCAAGATTGT TGACTTTGGC 
AGCTCTTGTC AGTTGGGGCA GAGGATATAC CAGTATATTC AGAGTCGCTT CTATCGGTCT 
CCAGAGGTGC TACTGGGAAT GCCTTATGAC CTTGCTATCG ACATGTGGTC CCTTGGATGT 
ATCTTGGTTG AAATGCACAC TGGAGAGCCT CTGTTCAGTG GTGCCAATGA GGTGGATCAG 
ATGAATAAAA TAGTGGAAGT CTTGGGCATC CCACCTGCTC ATATTCTTGA CCAAGCACCG 
AAAGCAAGAA AGTTCTTTGA GAAGTTGCCT GATGGCACTT GGAGCTTAAA GAAGACCAAA 
GATGGAAAAC GGGAGTACAA ACCACCAGGA ACCCGTAAAC TTCATAATAT TCTTGGAGTG 
GAAACAGGAG GACCTGGCGG GCGGCGTGCT GGGGAGTCAG GTCACACTGT AGCTGACTAC 
TTGAAGTTCA AAGACCTCAT TTTAAGGATG CTTGATTATG ACCCCAAAAC TCGGATTCAA 
CCTTATTATG CCCTGCAGCA CAGTTTTTTC AAGAAAACAG CTGATGAAGG TACAAACACA 
AGCAACAGTG TGTCCACCAG CCCTGCCATG GAGCAGTCCC AGTCTTCAGG CACCACCTCC 
AGCACCTCCT CCAGCTCAGG TGGATCCTCG GGAACGAGCA ACAGTGGGAG AGCCAGGTCG 
GATCCGACGC ACCAGCATCG GCACAGTGGC GGGCACTTCG CTGCTGCTGT CCAGGCCATG 
GACTGTGAGA CACATAGTCC CCAGGTGCGC CAGCAGTTTC CGGCTCCTCT GGGCTGGTCA 
GGCACTGAAG CTCCTACACA AGTCACTGTT GAAACTCATC CTGTTCAAGA AACAACCTTT 
CATGTAGCCC CTCAGCAGAA TGCATTGCAT CATCACCATG GAAACAGTTC CCATCATCAC 
CACCACCACC ATCACCACCA CCACCACCAT GGACAGCAAG CCTTGGGTAA CCGGACCAGG 
CCAAGGGTCT ACAATTCTCC AACAAATAGC TCCTCTACCC AGGATTCTAT GGAGGTTGGC 
CACAGTCACC ACTCCATGAC ATCCCTGTCT TCCTCAACAA CTTCTTCCTC GACATCTTCC 
TCCTCTACTG GTAATCAAGG CAATCAGGCC TATCAGAACC GCCCAGTGGC TGCTAACACC 
TTGGACTTTG GACAGAATGG AGCTATGGAC GTTAATTTGA CCGTCTACTC CAATCCCCGC 
CAAGAGACTG GCATAGCTGG ACATCCAACA TACCAATTTT CTGCTAATAC AGGTCCTGCA 
CATTACATGA CTGAAGGACA TCTGACGATG AGGCAAGGGG CTGATAGAGA AGAGTCTCCC 
ATGACAGGAG TTTGTGTGCA ACAGAGTCCT GTAGCTAGCT CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766787.1
CDS	278..2542
Translation	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS

Target ORF information:

RefSeq Version	XM_008768565.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768565.2

ORF Insert Sequence:

ATGCATACAG GAGGAGAGAC TTCAGCATGC AAACCTTCAT CTGTCCGGCT CGCACCGTCA 
TTCTCATTCC ATGCTGCTGG CCTTCAGATG GCTGCACAGA TGCCCCATTC ACATCAGTAC 
AGTGACCGTC GCCAGCCAAA CATAAGTGAC CAGCAGGTTT CTGCCTTATC ATATTCTGAC 
CAGATTCAGC AACCTCTAAC TAACCAGAGG CGGATGCCCC AAACCTTCCG TGATCCAGCA 
ACTGCTCCTC TGAGAAAACT CTCTGTGGAC TTGATCAAAA CATACAAGCA TATTAATGAG 
GTTTACTATG CAAAAAAGAA GCGAAGACAC CAACAGGGCC AGGGGGACGA TTCTAGTCAT 
AAGAAGGAGC GGAAGGTTTA CAACGATGGT TACGATGACG ATAACTATGA TTACATTGTA 
AAAAACGGAG AAAAGTGGAT GGACCGTTAT GAAATCGACT CCTTAATAGG CAAAGGTTCA 
TTTGGACAGG TTGTGAAAGC ATATGACAGA GTGGAACAAG AATGGGTCGC CATTAAAATC 
ATCAAGAACA AGAAGGCGTT TCTGAATCAA GCGCAGATAG AAGTGCGGCT GCTTGAGCTC 
ATGAACAAAC ATGACACTGA GATGAAGTAC TACATAGTGC ATTTGAAACG CCACTTTATG 
TTTCGGAACC ATCTCTGTCT AGTGTTTGAA ATGCTGTCCT ATAATCTCTA TGATTTGTTG 
AGGAACACCA ACTTCCGAGG GGTCTCTTTG AACCTGACAC GAAAGTTTGC ACAACAGATG 
TGCACAGCAT TGCTTTTCCT TGCGACTCCA GAACTTAGTA TCATTCACTG TGACTTAAAG 
CCGGAGAACA TCCTTCTGTG TAACCCCAAA CGAAGTGCAA TCAAGATTGT TGACTTTGGC 
AGCTCTTGTC AGTTGGGGCA GAGGATATAC CAGTATATTC AGAGTCGCTT CTATCGGTCT 
CCAGAGGTGC TACTGGGAAT GCCTTATGAC CTTGCTATCG ACATGTGGTC CCTTGGATGT 
ATCTTGGTTG AAATGCACAC TGGAGAGCCT CTGTTCAGTG GTGCCAATGA GGTGGATCAG 
ATGAATAAAA TAGTGGAAGT CTTGGGCATC CCACCTGCTC ATATTCTTGA CCAAGCACCG 
AAAGCAAGAA AGTTCTTTGA GAAGTTGCCT GATGGCACTT GGAGCTTAAA GAAGACCAAA 
GATGGAAAAC GGGAGTACAA ACCACCAGGA ACCCGTAAAC TTCATAATAT TCTTGGAGTG 
GAAACAGGAG GACCTGGCGG GCGGCGTGCT GGGGAGTCAG GTCACACTGT AGCTGACTAC 
TTGAAGTTCA AAGACCTCAT TTTAAGGATG CTTGATTATG ACCCCAAAAC TCGGATTCAA 
CCTTATTATG CCCTGCAGCA CAGTTTTTTC AAGAAAACAG CTGATGAAGG TACAAACACA 
AGCAACAGTG TGTCCACCAG CCCTGCCATG GAGCAGTCCC AGTCTTCAGG CACCACCTCC 
AGCACCTCCT CCAGCTCAGG TGGATCCTCG GGAACGAGCA ACAGTGGGAG AGCCAGGTCG 
GATCCGACGC ACCAGCATCG GCACAGTGGC GGGCACTTCG CTGCTGCTGT CCAGGCCATG 
GACTGTGAGA CACATAGTCC CCAGGTGCGC CAGCAGTTTC CGGCTCCTCT GGGCTGGTCA 
GGCACTGAAG CTCCTACACA AGTCACTGTT GAAACTCATC CTGTTCAAGA AACAACCTTT 
CATGTAGCCC CTCAGCAGAA TGCATTGCAT CATCACCATG GAAACAGTTC CCATCATCAC 
CACCACCACC ATCACCACCA CCACCACCAT GGACAGCAAG CCTTGGGTAA CCGGACCAGG 
CCAAGGGTCT ACAATTCTCC AACAAATAGC TCCTCTACCC AGGATTCTAT GGAGGTTGGC 
CACAGTCACC ACTCCATGAC ATCCCTGTCT TCCTCAACAA CTTCTTCCTC GACATCTTCC 
TCCTCTACTG GTAATCAAGG CAATCAGGCC TATCAGAACC GCCCAGTGGC TGCTAACACC 
TTGGACTTTG GACAGAATGG AGCTATGGAC GTTAATTTGA CCGTCTACTC CAATCCCCGC 
CAAGAGACTG GCATAGCTGG ACATCCAACA TACCAATTTT CTGCTAATAC AGGTCCTGCA 
CATTACATGA CTGAAGGACA TCTGACGATG AGGCAAGGGG CTGATAGAGA AGAGTCTCCC 
ATGACAGGAG TTTGTGTGCA ACAGAGTCCT GTAGCTAGCT CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Neurobiology of disease10676-88(2017 Oct)
Garc?a-Cerro S,Rueda N,Vidal V,Lantigua S,Mart?nez-Cu? C

Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice.
Scientific reports7(1)619(2017 Apr)
Yin X,Jin N,Shi J,Zhang Y,Wu Y,Gong CX,Iqbal K,Liu F

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.
Scientific reports743331(2017 Mar)
Birling MC,Schaeffer L,Andr? P,Lindner L,Mar?chal D,Ayadi A,Sorg T,Pavlovic G,H?rault Y

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.
Cardiovascular research110(3)381-94(2016 06)
Hille S,Dierck F,K?hl C,Sosna J,Adam-Klages S,Adam D,L?llmann-Rauch R,Frey N,Kuhn C

Involvement of the dual-specificity tyrosine phosphorylation-regulated kinase 1A-alternative splicing factor-calcium/calmodulin-dependent protein kinase II? signaling pathway in myocardial infarction-induced heart failure of rats.
Journal of cardiac failure21(9)751-60(2015 Sep)
He J,Yao J,Sheng H,Zhu J

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Dyrk1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報