Ghr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ghr
Entrez Gene ID	25235
Full Name	growth hormone receptor
Synonyms	GHR/BP
General protein information	Preferred Names growth hormone receptor Names growth hormone receptor GH receptor growth hormone receptor precursor splice variant D56 growth hormone receptor variant d5-6 growth hormone receptor/binding protein somatotropin receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q16
Summary	may play a role in chondrocyte differentiation and positive regulation of longitudinal bond growth and [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008760754.1	XP_008758976.1	growth hormone receptor isoform X3
XM_008760752.2	XP_008758974.1	growth hormone receptor isoform X1
XM_008760753.2	XP_008758975.1	growth hormone receptor isoform X2
NM_017094.1	NP_058790.1	growth hormone receptor precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	GHR	NP_788781.1
Mus musculus (house mouse)	Ghr	NP_001273299.1
Gallus gallus (chicken)	GHR	NP_001001293.1
Danio rerio (zebrafish)	ghra	NP_001077047.1
Homo sapiens (human)	GHR	NP_001229328.1
	GHR	NP_001036132.1
Rattus norvegicus (Norway rat)	Ghr	NP_058790.1
Pan troglodytes (chimpanzee)	GHR	XP_003950612.1
Canis lupus familiaris (dog)	GHR	NP_001003123.1
Xenopus tropicalis (tropical clawed frog)	ghr	XP_002933093.2

Gene Ontology
Bibliography

Related articles in PubMed

Clinical and biochemical consequences of an intragenic growth hormone receptor (GHR) deletion in a large Chinese pedigree.
Klammt J, Shen S, Kiess W, Kratzsch J, Stobbe H, Vogel M, Luo F, Pf?ffle R
Clinical endocrinology82(3)453-61(2015 Mar)

Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women.
Claessen KM, Kloppenburg M, Kroon HM, Bijsterbosch J, Pereira AM, Romijn JA, van der Straaten T, Nelissen RG, Hofman A, Uitterlinden AG, Duijnisveld BJ, Lakenberg N, Beekman M, van Meurs JB, Slagboom PE, Biermasz NR, Meulenbelt I
Annals of the rheumatic diseases73(2)433-6(2014 Feb)

Post-receptor crosstalk between growth hormone and insulin signal in rats born small for gestational age with catch-up growth.
Deng HZ, Deng H, Cen CQ, Chen KY, Du ML
PloS one9(6)e100459(2014)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

The expression of growth hormone receptor gene transcript in the prefrontal cortex is affected in male mice with diabetes-induced learning impairments.
Enhamre E, Carlsson A, Gr?nbladh A, Watanabe H, Hallberg M, Nyberg F
Neuroscience letters523(1)82-6(2012 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

receptor crosstalk between growth hormone and insulin signal in rats born small for gestational age with catch-up growth
Title: Post-receptor crosstalk between growth hormone and insulin signal in rats born small for gestational age with catch-up growth.

Compared to the rats in the control group, the rats in the HF group had the expression levels of 12 genes with significant changes, Agrp, Ghrl, and Nr3c1, Apoa4, Cntf, Ghr, IL-1beta, Ins1, Lepr,Sort, Adcyap1r1 and Adrb1.
Title: Green tea polyphenols reduce body weight in rats by modulating obesity-related genes.

Data show that TrCP acts in an early stage of cargo selection: both TrCP silencing and mutation of the ubiquitin-dependent endocytosis motif force the GHR to recycle between endosomes and the plasma membrane.
Title: SCF(TrCP) acts in endosomal sorting of the GH receptor.

The growth hormone receptor expression in the brain was lower during fetal period than in adults, while in the pituitary gland, the expression is markedly higher in fetuses, suggesting a yet unknown role of growth hormone in the development of this organ.
Title: Regional distribution and ontogeny of the first exon variants of the rat growth hormone receptor mRNA in the brain and the pituitary gland.

Growth hormone receptor mRNA levels decrease in hypothalamus during normal pregnancy while growth hormone expression rises in the pituitary.
Title: Importance of ghrelin in hypothalamus-pituitary axis on growth hormone release during normal pregnancy in the rat.

The following Ghr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ghr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa42681	NM_017094.1 Latest version!	Rattus norvegicus growth hormone receptor (Ghr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa42681	XM_008760754.1 Latest version!	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43033	XM_008760752.2 Latest version!	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43034	XM_008760753.2 Latest version!	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ghr ( NM_017094.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058790.1 Rattus norvegicus growth hormone receptor (Ghr), mRNA.

Price & Availability↑

CloneID	ORa42681
Clone ID Related Accession (Same CDS sequence)	XM_008760754.1 , NM_017094.1
Accession Version	NM_017094.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	growth hormone receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J04811.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J04811.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGATCTTT GGCGGGTGTT CTTAACCCTG GCACTGGCAG TCTCCAGCGA CATGTTTCCT 
GGAAGTGGGG CTACACCAGC TACTCTTGGC AAAGCTTCCC CGGTTCTGCA AAGAATTAAT 
CCAAGCCTGA GGGAAAGTTC CTCTGGAAAG CCTCGATTCA CCAAGTGTCG TTCCCCTGAA 
CTGGAGACCT TTTCATGCTA CTGGACAGAA GGGGATGATC ATAATTTAAA GGTCCCGGGA 
TCTATTCAGC TATACTATGC TAGAAGAATT GCTCATGAAT GGACCCCGGA ATGGAAAGAA 
TGCCCTGATT ATGTCTCTGC TGGAGCAAAC AGCTGTTACT TCAACTCATC GTATACCTCC 
ATTTGGATAC CCTACTGCAT TAAGCTTACT ACAAATGGTG ATTTGTTGGA CGAAAAGTGT 
TTCACTGTTG ATGAAATAGT GCAACCTGAT CCGCCCATTG GCCTCAACTG GACTTTACTA 
AACATCAGTT TGCCTGGGAT CCGTGGAGAT ATCCAAGTGA GTTGGCAGCC ACCGCCCAGT 
GCCGATGTTC TGAAGGGATG GATAATTCTG GAGTATGAAA TTCAGTACAA AGAAGTAAAT 
GAAACAAAAT GGAAAACGAT GAGCCCGATA TGGTCAACAT CAGTCCCACT GTACTCACTG 
AGACTGGATA AAGAGCACGA AGTGCGTGTG AGATCCAGAC AACGGAGCTT CGAAAAGTAC 
AGCGAGTTCA GTGAAGTACT CCGTGTAACG TTTCCTCAGA TGGACACACT GGCAGCATGT 
GAAGAAGATT TCCGGTTTCC ATGGTTCTTA ATTATTATCT TTGGAATATT TGGAGTAGCA 
GTGATGCTAT TTGTAGTTAT ATTTTCAAAG CAGCAAAGGA TTAAGATGCT GATTTTACCC 
CCAGTACCAG TTCCAAAGAT TAAAGGGATT GATCCAGATC TTCTCAAGGA AGGAAAATTG 
GAGGAGGTGA ACACCATCTT GGGCATTCAT GATAACTACA AACCCGACTT CTACAATGAT 
GACTCCTGGG TTGAGTTCAT TGAGCTGGAT ATTGATGATG CGGATGAGAA GACTGAAGAG 
TCAGACACCG ACAGACTTCT AAGCGATGAC CAGGAGAAAT CAGCTGGTAT CCTTGGAGCA 
AAGGATGACG ATTCTGGACG TACCAGCTGT TATGACCCTG ACATTTTGGA TACCGATTTC 
CACACCAGTG ACATGTGCGA TGGTACCTCG GAGTTTGCTC AGCCGCAGAA GTTAAAAGCA 
GAAGCTGATC TCTTGTGCCT TGACCAGAAG AATCTGAAGA ACTCGCCTTA TGATGCTTCC 
CTTGGCTCTC TGCACCCCTC CATTACCCTG ACAATGGAAG ACAAACCACA GCCACTTCTG 
GGCAGTGAAA CTGAGTCAAC CCACCAACTC CCCTCTACAC CAATGAGCAG TCCCGTGTCA 
CTGGCAAACA TTGACTTTTA TGCCCAAGTA AGCGACATTA CACCAGCAGG TGGTGTAGTC 
CTTTCTCCAG GCCAAAAGAT TAAGGCAGGG TTAGCCCAGG GCAACACCCA GCTGGAGGTG 
GCCGCGCCCT GCCAAGAAAA TTACAGCATG AACAGTGCCT ACTTCTGTGA GTCAGATGCC 
AAAAAGTGCA TCGCTGCGGC CCCTCACATG GAGGCCACGA CATGTGTAAA ACCAAGCTTT 
AACCAAGAGG ACATTTACAT CACCACAGAA AGCCTTACCA CTACTGCCCG AATGTCCGAG 
ACAGCAGATA CCGCTCCAGA TGCTGAGCCT GTCCCAGACT ACACCACGGT TCACACCGTG 
AAGTCCCCAA GGGGCCTTAT ACTCAACGCG ACTGCTTTGC CTTTGCCTGA CAAAAAGAAG 
TTTCTCTCCT CATGTGGCTA TGTGAGCACA GACCAACTGA ACAAAATCAT GCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058790.1
CDS	191..2107
Translation	MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ

Target ORF information:

RefSeq Version	NM_017094.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus growth hormone receptor (Ghr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017094.1

ORF Insert Sequence:

ATGGATCTTT GGCGGGTGTT CTTAACCCTG GCACTGGCAG TCTCCAGCGA CATGTTTCCT 
GGAAGTGGGG CTACACCAGC TACTCTTGGC AAAGCTTCCC CGGTTCTGCA AAGAATTAAT 
CCAAGCCTGA GGGAAAGTTC CTCTGGAAAG CCTCGATTCA CCAAGTGTCG TTCCCCTGAA 
CTGGAGACCT TTTCATGCTA CTGGACAGAA GGGGATGATC ATAATTTAAA GGTCCCGGGA 
TCTATTCAGC TATACTATGC TAGAAGAATT GCTCATGAAT GGACCCCGGA ATGGAAAGAA 
TGCCCTGATT ATGTCTCTGC TGGAGCAAAC AGCTGTTACT TCAACTCATC GTATACCTCC 
ATTTGGATAC CCTACTGCAT TAAGCTTACT ACAAATGGTG ATTTGTTGGA CGAAAAGTGT 
TTCACTGTTG ATGAAATAGT GCAACCTGAT CCGCCCATTG GCCTCAACTG GACTTTACTA 
AACATCAGTT TGCCTGGGAT CCGTGGAGAT ATCCAAGTGA GTTGGCAGCC ACCGCCCAGT 
GCCGATGTTC TGAAGGGATG GATAATTCTG GAGTATGAAA TTCAGTACAA AGAAGTAAAT 
GAAACAAAAT GGAAAACGAT GAGCCCGATA TGGTCAACAT CAGTCCCACT GTACTCACTG 
AGACTGGATA AAGAGCACGA AGTGCGTGTG AGATCCAGAC AACGGAGCTT CGAAAAGTAC 
AGCGAGTTCA GTGAAGTACT CCGTGTAACG TTTCCTCAGA TGGACACACT GGCAGCATGT 
GAAGAAGATT TCCGGTTTCC ATGGTTCTTA ATTATTATCT TTGGAATATT TGGAGTAGCA 
GTGATGCTAT TTGTAGTTAT ATTTTCAAAG CAGCAAAGGA TTAAGATGCT GATTTTACCC 
CCAGTACCAG TTCCAAAGAT TAAAGGGATT GATCCAGATC TTCTCAAGGA AGGAAAATTG 
GAGGAGGTGA ACACCATCTT GGGCATTCAT GATAACTACA AACCCGACTT CTACAATGAT 
GACTCCTGGG TTGAGTTCAT TGAGCTGGAT ATTGATGATG CGGATGAGAA GACTGAAGAG 
TCAGACACCG ACAGACTTCT AAGCGATGAC CAGGAGAAAT CAGCTGGTAT CCTTGGAGCA 
AAGGATGACG ATTCTGGACG TACCAGCTGT TATGACCCTG ACATTTTGGA TACCGATTTC 
CACACCAGTG ACATGTGCGA TGGTACCTCG GAGTTTGCTC AGCCGCAGAA GTTAAAAGCA 
GAAGCTGATC TCTTGTGCCT TGACCAGAAG AATCTGAAGA ACTCGCCTTA TGATGCTTCC 
CTTGGCTCTC TGCACCCCTC CATTACCCTG ACAATGGAAG ACAAACCACA GCCACTTCTG 
GGCAGTGAAA CTGAGTCAAC CCACCAACTC CCCTCTACAC CAATGAGCAG TCCCGTGTCA 
CTGGCAAACA TTGACTTTTA TGCCCAAGTA AGCGACATTA CACCAGCAGG TGGTGTAGTC 
CTTTCTCCAG GCCAAAAGAT TAAGGCAGGG TTAGCCCAGG GCAACACCCA GCTGGAGGTG 
GCCGCGCCCT GCCAAGAAAA TTACAGCATG AACAGTGCCT ACTTCTGTGA GTCAGATGCC 
AAAAAGTGCA TCGCTGCGGC CCCTCACATG GAGGCCACGA CATGTGTAAA ACCAAGCTTT 
AACCAAGAGG ACATTTACAT CACCACAGAA AGCCTTACCA CTACTGCCCG AATGTCCGAG 
ACAGCAGATA CCGCTCCAGA TGCTGAGCCT GTCCCAGACT ACACCACGGT TCACACCGTG 
AAGTCCCCAA GGGGCCTTAT ACTCAACGCG ACTGCTTTGC CTTTGCCTGA CAAAAAGAAG 
TTTCTCTCCT CATGTGGCTA TGTGAGCACA GACCAACTGA ACAAAATCAT GCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ghr ( XM_008760754.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758976.1 Rattus norvegicus growth hormone receptor (Ghr), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa42681
Clone ID Related Accession (Same CDS sequence)	XM_008760754.1 , NM_017094.1
Accession Version	XM_008760754.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	growth hormone receptor isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTTT GGCGGGTGTT CTTAACCCTG GCACTGGCAG TCTCCAGCGA CATGTTTCCT 
GGAAGTGGGG CTACACCAGC TACTCTTGGC AAAGCTTCCC CGGTTCTGCA AAGAATTAAT 
CCAAGCCTGA GGGAAAGTTC CTCTGGAAAG CCTCGATTCA CCAAGTGTCG TTCCCCTGAA 
CTGGAGACCT TTTCATGCTA CTGGACAGAA GGGGATGATC ATAATTTAAA GGTCCCGGGA 
TCTATTCAGC TATACTATGC TAGAAGAATT GCTCATGAAT GGACCCCGGA ATGGAAAGAA 
TGCCCTGATT ATGTCTCTGC TGGAGCAAAC AGCTGTTACT TCAACTCATC GTATACCTCC 
ATTTGGATAC CCTACTGCAT TAAGCTTACT ACAAATGGTG ATTTGTTGGA CGAAAAGTGT 
TTCACTGTTG ATGAAATAGT GCAACCTGAT CCGCCCATTG GCCTCAACTG GACTTTACTA 
AACATCAGTT TGCCTGGGAT CCGTGGAGAT ATCCAAGTGA GTTGGCAGCC ACCGCCCAGT 
GCCGATGTTC TGAAGGGATG GATAATTCTG GAGTATGAAA TTCAGTACAA AGAAGTAAAT 
GAAACAAAAT GGAAAACGAT GAGCCCGATA TGGTCAACAT CAGTCCCACT GTACTCACTG 
AGACTGGATA AAGAGCACGA AGTGCGTGTG AGATCCAGAC AACGGAGCTT CGAAAAGTAC 
AGCGAGTTCA GTGAAGTACT CCGTGTAACG TTTCCTCAGA TGGACACACT GGCAGCATGT 
GAAGAAGATT TCCGGTTTCC ATGGTTCTTA ATTATTATCT TTGGAATATT TGGAGTAGCA 
GTGATGCTAT TTGTAGTTAT ATTTTCAAAG CAGCAAAGGA TTAAGATGCT GATTTTACCC 
CCAGTACCAG TTCCAAAGAT TAAAGGGATT GATCCAGATC TTCTCAAGGA AGGAAAATTG 
GAGGAGGTGA ACACCATCTT GGGCATTCAT GATAACTACA AACCCGACTT CTACAATGAT 
GACTCCTGGG TTGAGTTCAT TGAGCTGGAT ATTGATGATG CGGATGAGAA GACTGAAGAG 
TCAGACACCG ACAGACTTCT AAGCGATGAC CAGGAGAAAT CAGCTGGTAT CCTTGGAGCA 
AAGGATGACG ATTCTGGACG TACCAGCTGT TATGACCCTG ACATTTTGGA TACCGATTTC 
CACACCAGTG ACATGTGCGA TGGTACCTCG GAGTTTGCTC AGCCGCAGAA GTTAAAAGCA 
GAAGCTGATC TCTTGTGCCT TGACCAGAAG AATCTGAAGA ACTCGCCTTA TGATGCTTCC 
CTTGGCTCTC TGCACCCCTC CATTACCCTG ACAATGGAAG ACAAACCACA GCCACTTCTG 
GGCAGTGAAA CTGAGTCAAC CCACCAACTC CCCTCTACAC CAATGAGCAG TCCCGTGTCA 
CTGGCAAACA TTGACTTTTA TGCCCAAGTA AGCGACATTA CACCAGCAGG TGGTGTAGTC 
CTTTCTCCAG GCCAAAAGAT TAAGGCAGGG TTAGCCCAGG GCAACACCCA GCTGGAGGTG 
GCCGCGCCCT GCCAAGAAAA TTACAGCATG AACAGTGCCT ACTTCTGTGA GTCAGATGCC 
AAAAAGTGCA TCGCTGCGGC CCCTCACATG GAGGCCACGA CATGTGTAAA ACCAAGCTTT 
AACCAAGAGG ACATTTACAT CACCACAGAA AGCCTTACCA CTACTGCCCG AATGTCCGAG 
ACAGCAGATA CCGCTCCAGA TGCTGAGCCT GTCCCAGACT ACACCACGGT TCACACCGTG 
AAGTCCCCAA GGGGCCTTAT ACTCAACGCG ACTGCTTTGC CTTTGCCTGA CAAAAAGAAG 
TTTCTCTCCT CATGTGGCTA TGTGAGCACA GACCAACTGA ACAAAATCAT GCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758976.1
CDS	469..2385
Translation	MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ

Target ORF information:

RefSeq Version	XM_008760754.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760754.1

ORF Insert Sequence:

ATGGATCTTT GGCGGGTGTT CTTAACCCTG GCACTGGCAG TCTCCAGCGA CATGTTTCCT 
GGAAGTGGGG CTACACCAGC TACTCTTGGC AAAGCTTCCC CGGTTCTGCA AAGAATTAAT 
CCAAGCCTGA GGGAAAGTTC CTCTGGAAAG CCTCGATTCA CCAAGTGTCG TTCCCCTGAA 
CTGGAGACCT TTTCATGCTA CTGGACAGAA GGGGATGATC ATAATTTAAA GGTCCCGGGA 
TCTATTCAGC TATACTATGC TAGAAGAATT GCTCATGAAT GGACCCCGGA ATGGAAAGAA 
TGCCCTGATT ATGTCTCTGC TGGAGCAAAC AGCTGTTACT TCAACTCATC GTATACCTCC 
ATTTGGATAC CCTACTGCAT TAAGCTTACT ACAAATGGTG ATTTGTTGGA CGAAAAGTGT 
TTCACTGTTG ATGAAATAGT GCAACCTGAT CCGCCCATTG GCCTCAACTG GACTTTACTA 
AACATCAGTT TGCCTGGGAT CCGTGGAGAT ATCCAAGTGA GTTGGCAGCC ACCGCCCAGT 
GCCGATGTTC TGAAGGGATG GATAATTCTG GAGTATGAAA TTCAGTACAA AGAAGTAAAT 
GAAACAAAAT GGAAAACGAT GAGCCCGATA TGGTCAACAT CAGTCCCACT GTACTCACTG 
AGACTGGATA AAGAGCACGA AGTGCGTGTG AGATCCAGAC AACGGAGCTT CGAAAAGTAC 
AGCGAGTTCA GTGAAGTACT CCGTGTAACG TTTCCTCAGA TGGACACACT GGCAGCATGT 
GAAGAAGATT TCCGGTTTCC ATGGTTCTTA ATTATTATCT TTGGAATATT TGGAGTAGCA 
GTGATGCTAT TTGTAGTTAT ATTTTCAAAG CAGCAAAGGA TTAAGATGCT GATTTTACCC 
CCAGTACCAG TTCCAAAGAT TAAAGGGATT GATCCAGATC TTCTCAAGGA AGGAAAATTG 
GAGGAGGTGA ACACCATCTT GGGCATTCAT GATAACTACA AACCCGACTT CTACAATGAT 
GACTCCTGGG TTGAGTTCAT TGAGCTGGAT ATTGATGATG CGGATGAGAA GACTGAAGAG 
TCAGACACCG ACAGACTTCT AAGCGATGAC CAGGAGAAAT CAGCTGGTAT CCTTGGAGCA 
AAGGATGACG ATTCTGGACG TACCAGCTGT TATGACCCTG ACATTTTGGA TACCGATTTC 
CACACCAGTG ACATGTGCGA TGGTACCTCG GAGTTTGCTC AGCCGCAGAA GTTAAAAGCA 
GAAGCTGATC TCTTGTGCCT TGACCAGAAG AATCTGAAGA ACTCGCCTTA TGATGCTTCC 
CTTGGCTCTC TGCACCCCTC CATTACCCTG ACAATGGAAG ACAAACCACA GCCACTTCTG 
GGCAGTGAAA CTGAGTCAAC CCACCAACTC CCCTCTACAC CAATGAGCAG TCCCGTGTCA 
CTGGCAAACA TTGACTTTTA TGCCCAAGTA AGCGACATTA CACCAGCAGG TGGTGTAGTC 
CTTTCTCCAG GCCAAAAGAT TAAGGCAGGG TTAGCCCAGG GCAACACCCA GCTGGAGGTG 
GCCGCGCCCT GCCAAGAAAA TTACAGCATG AACAGTGCCT ACTTCTGTGA GTCAGATGCC 
AAAAAGTGCA TCGCTGCGGC CCCTCACATG GAGGCCACGA CATGTGTAAA ACCAAGCTTT 
AACCAAGAGG ACATTTACAT CACCACAGAA AGCCTTACCA CTACTGCCCG AATGTCCGAG 
ACAGCAGATA CCGCTCCAGA TGCTGAGCCT GTCCCAGACT ACACCACGGT TCACACCGTG 
AAGTCCCCAA GGGGCCTTAT ACTCAACGCG ACTGCTTTGC CTTTGCCTGA CAAAAAGAAG 
TTTCTCTCCT CATGTGGCTA TGTGAGCACA GACCAACTGA ACAAAATCAT GCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ghr ( XM_008760752.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758974.1 Rattus norvegicus growth hormone receptor (Ghr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43033
Clone ID Related Accession (Same CDS sequence)	XM_008760752.2
Accession Version	XM_008760752.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1971bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	growth hormone receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760752.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCAAT CATCTGGGAC AATTGATACA CTCTTCTGGA ACCAGGTCTC AGGTATGGAT 
CTTTGGCGGG TGTTCTTAAC CCTGGCACTG GCAGTCTCCA GCGACATGTT TCCTGGAAGT 
GGGGCTACAC CAGCTACTCT TGGCAAAGCT TCCCCGGTTC TGCAAAGAAT TAATCCAAGC 
CTGAGGGAAA GTTCCTCTGG AAAGCCTCGA TTCACCAAGT GTCGTTCCCC TGAACTGGAG 
ACCTTTTCAT GCTACTGGAC AGAAGGGGAT GATCATAATT TAAAGGTCCC GGGATCTATT 
CAGCTATACT ATGCTAGAAG AATTGCTCAT GAATGGACCC CGGAATGGAA AGAATGCCCT 
GATTATGTCT CTGCTGGAGC AAACAGCTGT TACTTCAACT CATCGTATAC CTCCATTTGG 
ATACCCTACT GCATTAAGCT TACTACAAAT GGTGATTTGT TGGACGAAAA GTGTTTCACT 
GTTGATGAAA TAGTGCAACC TGATCCGCCC ATTGGCCTCA ACTGGACTTT ACTAAACATC 
AGTTTGCCTG GGATCCGTGG AGATATCCAA GTGAGTTGGC AGCCACCGCC CAGTGCCGAT 
GTTCTGAAGG GATGGATAAT TCTGGAGTAT GAAATTCAGT ACAAAGAAGT AAATGAAACA 
AAATGGAAAA CGATGAGCCC GATATGGTCA ACATCAGTCC CACTGTACTC ACTGAGACTG 
GATAAAGAGC ACGAAGTGCG TGTGAGATCC AGACAACGGA GCTTCGAAAA GTACAGCGAG 
TTCAGTGAAG TACTCCGTGT AACGTTTCCT CAGATGGACA CACTGGCAGC ATGTGAAGAA 
GATTTCCGGT TTCCATGGTT CTTAATTATT ATCTTTGGAA TATTTGGAGT AGCAGTGATG 
CTATTTGTAG TTATATTTTC AAAGCAGCAA AGGATTAAGA TGCTGATTTT ACCCCCAGTA 
CCAGTTCCAA AGATTAAAGG GATTGATCCA GATCTTCTCA AGGAAGGAAA ATTGGAGGAG 
GTGAACACCA TCTTGGGCAT TCATGATAAC TACAAACCCG ACTTCTACAA TGATGACTCC 
TGGGTTGAGT TCATTGAGCT GGATATTGAT GATGCGGATG AGAAGACTGA AGAGTCAGAC 
ACCGACAGAC TTCTAAGCGA TGACCAGGAG AAATCAGCTG GTATCCTTGG AGCAAAGGAT 
GACGATTCTG GACGTACCAG CTGTTATGAC CCTGACATTT TGGATACCGA TTTCCACACC 
AGTGACATGT GCGATGGTAC CTCGGAGTTT GCTCAGCCGC AGAAGTTAAA AGCAGAAGCT 
GATCTCTTGT GCCTTGACCA GAAGAATCTG AAGAACTCGC CTTATGATGC TTCCCTTGGC 
TCTCTGCACC CCTCCATTAC CCTGACAATG GAAGACAAAC CACAGCCACT TCTGGGCAGT 
GAAACTGAGT CAACCCACCA ACTCCCCTCT ACACCAATGA GCAGTCCCGT GTCACTGGCA 
AACATTGACT TTTATGCCCA AGTAAGCGAC ATTACACCAG CAGGTGGTGT AGTCCTTTCT 
CCAGGCCAAA AGATTAAGGC AGGGTTAGCC CAGGGCAACA CCCAGCTGGA GGTGGCCGCG 
CCCTGCCAAG AAAATTACAG CATGAACAGT GCCTACTTCT GTGAGTCAGA TGCCAAAAAG 
TGCATCGCTG CGGCCCCTCA CATGGAGGCC ACGACATGTG TAAAACCAAG CTTTAACCAA 
GAGGACATTT ACATCACCAC AGAAAGCCTT ACCACTACTG CCCGAATGTC CGAGACAGCA 
GATACCGCTC CAGATGCTGA GCCTGTCCCA GACTACACCA CGGTTCACAC CGTGAAGTCC 
CCAAGGGGCC TTATACTCAA CGCGACTGCT TTGCCTTTGC CTGACAAAAA GAAGTTTCTC 
TCCTCATGTG GCTATGTGAG CACAGACCAA CTGAACAAAA TCATGCAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758974.1
CDS	190..2160
Translation	MKQSSGTIDTLFWNQVSGMDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ

Target ORF information:

RefSeq Version	XM_008760752.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760752.2

ORF Insert Sequence:

ATGAAGCAAT CATCTGGGAC AATTGATACA CTCTTCTGGA ACCAGGTCTC AGGTATGGAT 
CTTTGGCGGG TGTTCTTAAC CCTGGCACTG GCAGTCTCCA GCGACATGTT TCCTGGAAGT 
GGGGCTACAC CAGCTACTCT TGGCAAAGCT TCCCCGGTTC TGCAAAGAAT TAATCCAAGC 
CTGAGGGAAA GTTCCTCTGG AAAGCCTCGA TTCACCAAGT GTCGTTCCCC TGAACTGGAG 
ACCTTTTCAT GCTACTGGAC AGAAGGGGAT GATCATAATT TAAAGGTCCC GGGATCTATT 
CAGCTATACT ATGCTAGAAG AATTGCTCAT GAATGGACCC CGGAATGGAA AGAATGCCCT 
GATTATGTCT CTGCTGGAGC AAACAGCTGT TACTTCAACT CATCGTATAC CTCCATTTGG 
ATACCCTACT GCATTAAGCT TACTACAAAT GGTGATTTGT TGGACGAAAA GTGTTTCACT 
GTTGATGAAA TAGTGCAACC TGATCCGCCC ATTGGCCTCA ACTGGACTTT ACTAAACATC 
AGTTTGCCTG GGATCCGTGG AGATATCCAA GTGAGTTGGC AGCCACCGCC CAGTGCCGAT 
GTTCTGAAGG GATGGATAAT TCTGGAGTAT GAAATTCAGT ACAAAGAAGT AAATGAAACA 
AAATGGAAAA CGATGAGCCC GATATGGTCA ACATCAGTCC CACTGTACTC ACTGAGACTG 
GATAAAGAGC ACGAAGTGCG TGTGAGATCC AGACAACGGA GCTTCGAAAA GTACAGCGAG 
TTCAGTGAAG TACTCCGTGT AACGTTTCCT CAGATGGACA CACTGGCAGC ATGTGAAGAA 
GATTTCCGGT TTCCATGGTT CTTAATTATT ATCTTTGGAA TATTTGGAGT AGCAGTGATG 
CTATTTGTAG TTATATTTTC AAAGCAGCAA AGGATTAAGA TGCTGATTTT ACCCCCAGTA 
CCAGTTCCAA AGATTAAAGG GATTGATCCA GATCTTCTCA AGGAAGGAAA ATTGGAGGAG 
GTGAACACCA TCTTGGGCAT TCATGATAAC TACAAACCCG ACTTCTACAA TGATGACTCC 
TGGGTTGAGT TCATTGAGCT GGATATTGAT GATGCGGATG AGAAGACTGA AGAGTCAGAC 
ACCGACAGAC TTCTAAGCGA TGACCAGGAG AAATCAGCTG GTATCCTTGG AGCAAAGGAT 
GACGATTCTG GACGTACCAG CTGTTATGAC CCTGACATTT TGGATACCGA TTTCCACACC 
AGTGACATGT GCGATGGTAC CTCGGAGTTT GCTCAGCCGC AGAAGTTAAA AGCAGAAGCT 
GATCTCTTGT GCCTTGACCA GAAGAATCTG AAGAACTCGC CTTATGATGC TTCCCTTGGC 
TCTCTGCACC CCTCCATTAC CCTGACAATG GAAGACAAAC CACAGCCACT TCTGGGCAGT 
GAAACTGAGT CAACCCACCA ACTCCCCTCT ACACCAATGA GCAGTCCCGT GTCACTGGCA 
AACATTGACT TTTATGCCCA AGTAAGCGAC ATTACACCAG CAGGTGGTGT AGTCCTTTCT 
CCAGGCCAAA AGATTAAGGC AGGGTTAGCC CAGGGCAACA CCCAGCTGGA GGTGGCCGCG 
CCCTGCCAAG AAAATTACAG CATGAACAGT GCCTACTTCT GTGAGTCAGA TGCCAAAAAG 
TGCATCGCTG CGGCCCCTCA CATGGAGGCC ACGACATGTG TAAAACCAAG CTTTAACCAA 
GAGGACATTT ACATCACCAC AGAAAGCCTT ACCACTACTG CCCGAATGTC CGAGACAGCA 
GATACCGCTC CAGATGCTGA GCCTGTCCCA GACTACACCA CGGTTCACAC CGTGAAGTCC 
CCAAGGGGCC TTATACTCAA CGCGACTGCT TTGCCTTTGC CTGACAAAAA GAAGTTTCTC 
TCCTCATGTG GCTATGTGAG CACAGACCAA CTGAACAAAA TCATGCAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ghr ( XM_008760753.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758975.1 Rattus norvegicus growth hormone receptor (Ghr), transcript variant X2, mRNA.

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CloneID	ORa43034
Clone ID Related Accession (Same CDS sequence)	XM_008760753.2
Accession Version	XM_008760753.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	growth hormone receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760753.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATAGCGA GGAGATGGAA CCAACTTAGA TGCCTCTCGA AGGTCTCAGG TATGGATCTT 
TGGCGGGTGT TCTTAACCCT GGCACTGGCA GTCTCCAGCG ACATGTTTCC TGGAAGTGGG 
GCTACACCAG CTACTCTTGG CAAAGCTTCC CCGGTTCTGC AAAGAATTAA TCCAAGCCTG 
AGGGAAAGTT CCTCTGGAAA GCCTCGATTC ACCAAGTGTC GTTCCCCTGA ACTGGAGACC 
TTTTCATGCT ACTGGACAGA AGGGGATGAT CATAATTTAA AGGTCCCGGG ATCTATTCAG 
CTATACTATG CTAGAAGAAT TGCTCATGAA TGGACCCCGG AATGGAAAGA ATGCCCTGAT 
TATGTCTCTG CTGGAGCAAA CAGCTGTTAC TTCAACTCAT CGTATACCTC CATTTGGATA 
CCCTACTGCA TTAAGCTTAC TACAAATGGT GATTTGTTGG ACGAAAAGTG TTTCACTGTT 
GATGAAATAG TGCAACCTGA TCCGCCCATT GGCCTCAACT GGACTTTACT AAACATCAGT 
TTGCCTGGGA TCCGTGGAGA TATCCAAGTG AGTTGGCAGC CACCGCCCAG TGCCGATGTT 
CTGAAGGGAT GGATAATTCT GGAGTATGAA ATTCAGTACA AAGAAGTAAA TGAAACAAAA 
TGGAAAACGA TGAGCCCGAT ATGGTCAACA TCAGTCCCAC TGTACTCACT GAGACTGGAT 
AAAGAGCACG AAGTGCGTGT GAGATCCAGA CAACGGAGCT TCGAAAAGTA CAGCGAGTTC 
AGTGAAGTAC TCCGTGTAAC GTTTCCTCAG ATGGACACAC TGGCAGCATG TGAAGAAGAT 
TTCCGGTTTC CATGGTTCTT AATTATTATC TTTGGAATAT TTGGAGTAGC AGTGATGCTA 
TTTGTAGTTA TATTTTCAAA GCAGCAAAGG ATTAAGATGC TGATTTTACC CCCAGTACCA 
GTTCCAAAGA TTAAAGGGAT TGATCCAGAT CTTCTCAAGG AAGGAAAATT GGAGGAGGTG 
AACACCATCT TGGGCATTCA TGATAACTAC AAACCCGACT TCTACAATGA TGACTCCTGG 
GTTGAGTTCA TTGAGCTGGA TATTGATGAT GCGGATGAGA AGACTGAAGA GTCAGACACC 
GACAGACTTC TAAGCGATGA CCAGGAGAAA TCAGCTGGTA TCCTTGGAGC AAAGGATGAC 
GATTCTGGAC GTACCAGCTG TTATGACCCT GACATTTTGG ATACCGATTT CCACACCAGT 
GACATGTGCG ATGGTACCTC GGAGTTTGCT CAGCCGCAGA AGTTAAAAGC AGAAGCTGAT 
CTCTTGTGCC TTGACCAGAA GAATCTGAAG AACTCGCCTT ATGATGCTTC CCTTGGCTCT 
CTGCACCCCT CCATTACCCT GACAATGGAA GACAAACCAC AGCCACTTCT GGGCAGTGAA 
ACTGAGTCAA CCCACCAACT CCCCTCTACA CCAATGAGCA GTCCCGTGTC ACTGGCAAAC 
ATTGACTTTT ATGCCCAAGT AAGCGACATT ACACCAGCAG GTGGTGTAGT CCTTTCTCCA 
GGCCAAAAGA TTAAGGCAGG GTTAGCCCAG GGCAACACCC AGCTGGAGGT GGCCGCGCCC 
TGCCAAGAAA ATTACAGCAT GAACAGTGCC TACTTCTGTG AGTCAGATGC CAAAAAGTGC 
ATCGCTGCGG CCCCTCACAT GGAGGCCACG ACATGTGTAA AACCAAGCTT TAACCAAGAG 
GACATTTACA TCACCACAGA AAGCCTTACC ACTACTGCCC GAATGTCCGA GACAGCAGAT 
ACCGCTCCAG ATGCTGAGCC TGTCCCAGAC TACACCACGG TTCACACCGT GAAGTCCCCA 
AGGGGCCTTA TACTCAACGC GACTGCTTTG CCTTTGCCTG ACAAAAAGAA GTTTCTCTCC 
TCATGTGGCT ATGTGAGCAC AGACCAACTG AACAAAATCA TGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758975.1
CDS	74..2041
Translation	MIARRWNQLRCLSKVSGMDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ

Target ORF information:

RefSeq Version	XM_008760753.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus growth hormone receptor (Ghr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760753.2

ORF Insert Sequence:

ATGATAGCGA GGAGATGGAA CCAACTTAGA TGCCTCTCGA AGGTCTCAGG TATGGATCTT 
TGGCGGGTGT TCTTAACCCT GGCACTGGCA GTCTCCAGCG ACATGTTTCC TGGAAGTGGG 
GCTACACCAG CTACTCTTGG CAAAGCTTCC CCGGTTCTGC AAAGAATTAA TCCAAGCCTG 
AGGGAAAGTT CCTCTGGAAA GCCTCGATTC ACCAAGTGTC GTTCCCCTGA ACTGGAGACC 
TTTTCATGCT ACTGGACAGA AGGGGATGAT CATAATTTAA AGGTCCCGGG ATCTATTCAG 
CTATACTATG CTAGAAGAAT TGCTCATGAA TGGACCCCGG AATGGAAAGA ATGCCCTGAT 
TATGTCTCTG CTGGAGCAAA CAGCTGTTAC TTCAACTCAT CGTATACCTC CATTTGGATA 
CCCTACTGCA TTAAGCTTAC TACAAATGGT GATTTGTTGG ACGAAAAGTG TTTCACTGTT 
GATGAAATAG TGCAACCTGA TCCGCCCATT GGCCTCAACT GGACTTTACT AAACATCAGT 
TTGCCTGGGA TCCGTGGAGA TATCCAAGTG AGTTGGCAGC CACCGCCCAG TGCCGATGTT 
CTGAAGGGAT GGATAATTCT GGAGTATGAA ATTCAGTACA AAGAAGTAAA TGAAACAAAA 
TGGAAAACGA TGAGCCCGAT ATGGTCAACA TCAGTCCCAC TGTACTCACT GAGACTGGAT 
AAAGAGCACG AAGTGCGTGT GAGATCCAGA CAACGGAGCT TCGAAAAGTA CAGCGAGTTC 
AGTGAAGTAC TCCGTGTAAC GTTTCCTCAG ATGGACACAC TGGCAGCATG TGAAGAAGAT 
TTCCGGTTTC CATGGTTCTT AATTATTATC TTTGGAATAT TTGGAGTAGC AGTGATGCTA 
TTTGTAGTTA TATTTTCAAA GCAGCAAAGG ATTAAGATGC TGATTTTACC CCCAGTACCA 
GTTCCAAAGA TTAAAGGGAT TGATCCAGAT CTTCTCAAGG AAGGAAAATT GGAGGAGGTG 
AACACCATCT TGGGCATTCA TGATAACTAC AAACCCGACT TCTACAATGA TGACTCCTGG 
GTTGAGTTCA TTGAGCTGGA TATTGATGAT GCGGATGAGA AGACTGAAGA GTCAGACACC 
GACAGACTTC TAAGCGATGA CCAGGAGAAA TCAGCTGGTA TCCTTGGAGC AAAGGATGAC 
GATTCTGGAC GTACCAGCTG TTATGACCCT GACATTTTGG ATACCGATTT CCACACCAGT 
GACATGTGCG ATGGTACCTC GGAGTTTGCT CAGCCGCAGA AGTTAAAAGC AGAAGCTGAT 
CTCTTGTGCC TTGACCAGAA GAATCTGAAG AACTCGCCTT ATGATGCTTC CCTTGGCTCT 
CTGCACCCCT CCATTACCCT GACAATGGAA GACAAACCAC AGCCACTTCT GGGCAGTGAA 
ACTGAGTCAA CCCACCAACT CCCCTCTACA CCAATGAGCA GTCCCGTGTC ACTGGCAAAC 
ATTGACTTTT ATGCCCAAGT AAGCGACATT ACACCAGCAG GTGGTGTAGT CCTTTCTCCA 
GGCCAAAAGA TTAAGGCAGG GTTAGCCCAG GGCAACACCC AGCTGGAGGT GGCCGCGCCC 
TGCCAAGAAA ATTACAGCAT GAACAGTGCC TACTTCTGTG AGTCAGATGC CAAAAAGTGC 
ATCGCTGCGG CCCCTCACAT GGAGGCCACG ACATGTGTAA AACCAAGCTT TAACCAAGAG 
GACATTTACA TCACCACAGA AAGCCTTACC ACTACTGCCC GAATGTCCGA GACAGCAGAT 
ACCGCTCCAG ATGCTGAGCC TGTCCCAGAC TACACCACGG TTCACACCGT GAAGTCCCCA 
AGGGGCCTTA TACTCAACGC GACTGCTTTG CCTTTGCCTG ACAAAAAGAA GTTTCTCTCC 
TCATGTGGCT ATGTGAGCAC AGACCAACTG AACAAAATCA TGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical and biochemical consequences of an intragenic growth hormone receptor (GHR) deletion in a large Chinese pedigree.
Clinical endocrinology82(3)453-61(2015 Mar)
Klammt J,Shen S,Kiess W,Kratzsch J,Stobbe H,Vogel M,Luo F,Pf?ffle R

Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women.
Annals of the rheumatic diseases73(2)433-6(2014 Feb)
Claessen KM,Kloppenburg M,Kroon HM,Bijsterbosch J,Pereira AM,Romijn JA,van der Straaten T,Nelissen RG,Hofman A,Uitterlinden AG,Duijnisveld BJ,Lakenberg N,Beekman M,van Meurs JB,Slagboom PE,Biermasz NR,Meulenbelt I

Post-receptor crosstalk between growth hormone and insulin signal in rats born small for gestational age with catch-up growth.
PloS one9(6)e100459(2014)
Deng HZ,Deng H,Cen CQ,Chen KY,Du ML

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

The expression of growth hormone receptor gene transcript in the prefrontal cortex is affected in male mice with diabetes-induced learning impairments.
Neuroscience letters523(1)82-6(2012 Aug)
Enhamre E,Carlsson A,Gr?nbladh A,Watanabe H,Hallberg M,Nyberg F

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Ghr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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