Egr4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Egr4
Entrez Gene ID	25129
Full Name	early growth response 4
Synonyms	Egr4l1,NGFI-C
General protein information	Preferred Names early growth response 4 Names early growth response protein 4 EGR-4 early response protein NGFI-C nerve growth factor-induced protein C zinc-finger transcription factor NGFI-C (early response gene)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34
Summary	acts as a transcriptional activator [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019137.1	NP_062010.1	early growth response protein 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	EGR4	NP_001956.3
Mus musculus (house mouse)	Egr4	NP_065621.1
Rattus norvegicus (Norway rat)	Egr4	NP_062010.1
Bos taurus (cattle)	EGR4	NP_001035587.1
Gallus gallus (chicken)	EGR4	XP_420888.1
Pan troglodytes (chimpanzee)	EGR4	XP_001142546.1
	LOC714407	XP_001104148.2
Canis lupus familiaris (dog)	EGR4	XP_540228.3
Xenopus tropicalis (tropical clawed frog)	egr4	XP_004911346.1

Gene Ontology
Bibliography

Related articles in PubMed

DNA-binding specificities of human transcription factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J
Cell152(1-2)327-39(2013 Jan)

Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke.
Mengozzi M, Cervellini I, Villa P, Erbayraktar Z, G?kmen N, Yilmaz O, Erbayraktar S, Manohasandra M, Van Hummelen P, Vandenabeele P, Chernajovsky Y, Annenkov A, Ghezzi P
Proceedings of the National Academy of Sciences of the United States of America109(24)9617-22(2012 Jun)

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome research14(4)750-7(2004 Apr)

Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Decker EL, Nehmann N, Kampen E, Eibel H, Zipfel PF, Skerka C
Nucleic acids research31(3)911-21(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Egr4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Egr4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03822	NM_019137.1 Latest version!	Rattus norvegicus early growth response 4 (Egr4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Egr4 ( NM_019137.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062010.1 Rattus norvegicus early growth response 4 (Egr4), mRNA.

Price & Availability↑

CloneID	ORa03822
Clone ID Related Accession (Same CDS sequence)	NM_019137.1
Accession Version	NM_019137.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	early growth response protein 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M92433.1. ##Evidence-Data-START## Transcript exon combination :: M65008.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689604 [ECO:0000348] ##Evidence-Data-END##

ATGCTCCACC TGAGCGACTT CTCCGGCCCC GACGCGCTCC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACA CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTCTGAGCA CCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCTTGGCA CCCTTCCCTA GCCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGTCCCGATG CCTTGTTGCC GGACCTTTAC 
TCCCCGGATC TGAGTTCGGC CGCCTTCCCG GAGGCGTTTT GGGAGGCCGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCCGGG 
CTGAGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCGGCCTT CAAAGGGCCC 
TACGCCCCCT GGGAGCTGCT GTCGGCCGGG GCTCCGGGGA ACTGTGGGTC GCAGGGAAGC 
TTCCAGACCA CCCCGGAGGC ACGCTTTTCC GCCGTGGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGT CCGGCTAGCA GACTCTACCC GCCAGGGGCC 
TACGATGCCT TCTCGCTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCGGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GTCCCTCAAG CGCAGCTGTC CCCGCTGGGC CTGCGCGGCG CCGCCACGGC AGACTTCTCC 
AAAGCCCTGG TGGCCGACCT CCCGGGGGGC AGCGGAGTGG CGGCGCCTTC ATCCCCCGCC 
ACCTCCTTCC CCGCGGCCAA AGCCCGGCGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCCGTGGA GAGCTGCGTG 
CGGACGTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACCGGCGA GAAGCCCTTC GCCTGCGACG TGTGCGGCCG CCGCTTCGCG 
CGCAGCGACG AGAAGAAGCG ACACAGCAAG GTGCACCTCA AGCAGAAGGC GCGCGCCGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CTTTCGCCGC GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062010.1
CDS	192..1628
Translation	MLHLSDFSGPDALLSKPTEGCAHTSPELPRLPARDAPSAAAYPGGDFLSWALSTCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPSPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGAPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPASRLYPPGAYDAFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAVPQAQLSPLGLRGAATADFSKALVADLPGGSGVAAPSSPATSFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRTFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL

Target ORF information:

RefSeq Version	NM_019137.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus early growth response 4 (Egr4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019137.1

ORF Insert Sequence:

ATGCTCCACC TGAGCGACTT CTCCGGCCCC GACGCGCTCC TCTCCAAGCC CACCGAAGGC 
TGCGCCCACA CCAGCCCCGA GCTGCCCCGG CTGCCTGCTA GGGACGCTCC CTCGGCCGCC 
GCGTATCCTG GAGGCGACTT CTTGAGCTGG GCTCTGAGCA CCTGCGGCGC CGGGGGGGAC 
TTAACAGACT CCTGCTTCCT GGAGGGCCCT GCACCCACGC CCCCTTCGGG CCTCAGCTAC 
AGCGGCAGCT TCTTCATCCA GGCGGTTCCC GAACACCCGC ACGACCCGGA GGCCCTCTTC 
AACCTCATGT CTGGCATCTT GGGCTTGGCA CCCTTCCCTA GCCCCGAGGC GGCAGCGTCT 
CGGTCCCCCC TGGATGTCCC TTTCCCCGCG GGTCCCGATG CCTTGTTGCC GGACCTTTAC 
TCCCCGGATC TGAGTTCGGC CGCCTTCCCG GAGGCGTTTT GGGAGGCCGC GCCTTCGGCG 
GGCGCTCCCT CGCAGTGCCT GTTCGAGCCC CAGCTCTCCC CGCCCGACGT CAAGCCCGGG 
CTGAGGGCGC CTCCCGCTTC GCCAGCGCTG GACGCTGCTG CTTCGGCCTT CAAAGGGCCC 
TACGCCCCCT GGGAGCTGCT GTCGGCCGGG GCTCCGGGGA ACTGTGGGTC GCAGGGAAGC 
TTCCAGACCA CCCCGGAGGC ACGCTTTTCC GCCGTGGGGA CCAAGGTCGA GGACCTGCTG 
TCCATCAGCT GCCCCGCCGA GCTGCCCGGT CCGGCTAGCA GACTCTACCC GCCAGGGGCC 
TACGATGCCT TCTCGCTGGC CCCAGGTGAC TTAGGGGAGG GGACCGAGGG CCTCCCGGCG 
CTGCTGACCC CTCCGGGCGG GGAGGGAGGG AGCGGCGGCG AAGGCGGAGA GTTCCTGGCC 
GTCCCTCAAG CGCAGCTGTC CCCGCTGGGC CTGCGCGGCG CCGCCACGGC AGACTTCTCC 
AAAGCCCTGG TGGCCGACCT CCCGGGGGGC AGCGGAGTGG CGGCGCCTTC ATCCCCCGCC 
ACCTCCTTCC CCGCGGCCAA AGCCCGGCGC AAGGGACGCC GGGGCGGCAA GTGCAGCGCG 
CGCTGCTTCT GCCCGCGGCC GCACGTCAAG GCCTTCGCCT GCCCCGTGGA GAGCTGCGTG 
CGGACGTTCG CGCGCTCCGA CGAGCTCAAC CGCCACCTGC GCATCCACAC GGGCCACAAG 
CCCTTCCAGT GCCGCATCTG CCTGCGCAAC TTCAGCCGCA GCGACCACCT CACCACGCAC 
GTGCGCACCC ACACCGGCGA GAAGCCCTTC GCCTGCGACG TGTGCGGCCG CCGCTTCGCG 
CGCAGCGACG AGAAGAAGCG ACACAGCAAG GTGCACCTCA AGCAGAAGGC GCGCGCCGAG 
GAGCGCCTCA AGGGCCTGGG CTTCTACTCG CTGGGCCTCT CTTTCGCCGC GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DNA-binding specificities of human transcription factors.
Cell152(1-2)327-39(2013 Jan)
Jolma A,Yan J,Whitington T,Toivonen J,Nitta KR,Rastas P,Morgunova E,Enge M,Taipale M,Wei G,Palin K,Vaquerizas JM,Vincentelli R,Luscombe NM,Hughes TR,Lemaire P,Ukkonen E,Kivioja T,Taipale J

Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke.
Proceedings of the National Academy of Sciences of the United States of America109(24)9617-22(2012 Jun)
Mengozzi M,Cervellini I,Villa P,Erbayraktar Z,G?kmen N,Yilmaz O,Erbayraktar S,Manohasandra M,Van Hummelen P,Vandenabeele P,Chernajovsky Y,Annenkov A,Ghezzi P

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Genome research14(4)750-7(2004 Apr)
Kwitek AE,Gullings-Handley J,Yu J,Carlos DC,Orlebeke K,Nie J,Eckert J,Lemke A,Andrae JW,Bromberg S,Pasko D,Chen D,Scheetz TE,Casavant TL,Soares MB,Sheffield VC,Tonellato PJ,Jacob HJ

Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Nucleic acids research31(3)911-21(2003 Feb)
Decker EL,Nehmann N,Kampen E,Eibel H,Zipfel PF,Skerka C

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Egr4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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