Cckar cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cckar
Entrez Gene ID	24889
Full Name	cholecystokinin A receptor
Synonyms	Cck-ar
General protein information	Preferred Names cholecystokinin A receptor Names cholecystokinin receptor type A CCK-A receptor CCK1-R cholecystokinin-1 receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14q11
Summary	G-protein coupled receptor activated by cholecystokinin; may be involved in food intake and insulin regulation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008770188.2	XP_008768410.1	cholecystokinin receptor type A isoform X1
XM_017599078.1	XP_017454567.1	cholecystokinin receptor type A isoform X2
XM_017599077.1	XP_017454566.1	cholecystokinin receptor type A isoform X1
NM_012688.3	NP_036820.1	cholecystokinin receptor type A

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCKAR	NP_000721.1
Mus musculus (house mouse)	Cckar	NP_033957.1
Anopheles gambiae (African malaria mosquito)	GPRCCK1	XP_309215.4
Caenorhabditis elegans (roundworm)	ckr-2	NP_001022844.1
	CCKAR	XP_001084186.1
Caenorhabditis elegans (roundworm)	ckr-1	NP_491918.3
Pan troglodytes (chimpanzee)	CCKAR	XP_526545.1
Canis lupus familiaris (dog)	CCKAR	NP_001012664.1
Danio rerio (zebrafish)	LOC569038	XP_697493.2
Xenopus tropicalis (tropical clawed frog)	cckar	XP_002939147.2
Bos taurus (cattle)	CCKAR	NP_001095335.1
Rattus norvegicus (Norway rat)	Cckar	NP_036820.1
Gallus gallus (chicken)	CCKAR	NP_001074970.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.
Parks GS, Wang L, Wang Z, Civelli O
The Journal of comparative neurology522(17)3817-33(2014 Dec)

Intraperitoneal CCK and fourth-intraventricular Apo AIV require both peripheral and NTS CCK1R to reduce food intake in male rats.
Lo CC, Davidson WS, Hibbard SK, Georgievsky M, Lee A, Tso P, Woods SC
Endocrinology155(5)1700-7(2014 May)

Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats.
Armbruszt S, Abraham H, Figler M, Kozicz T, Hajnal A
Journal of chemical neuroanatomy50-5175-84(2013 May)

Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity.
Petkova-Kirova P, Giovannini MG, Kalfin R, Rakovska A
Brain research bulletin89(5-6)177-84(2012 Dec)

Duodenal PKC-? and cholecystokinin signaling axis regulates glucose production.
Breen DM, Yue JT, Rasmussen BA, Kokorovic A, Cheung GW, Lam TK
Diabetes60(12)3148-53(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonistrated that Cckar and Melanin-concentrating hormone colization in neuron in the lateral hypothalamus (LH) and zona incerta (ZI), but MCHR1 mRNA is widely expressed throughout the brain.
Title: Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.

Data suggest that Apo AIV (apolipoprotein AIV) in NTS (nucleus of the solitary tract) or/and peripheral Cck (cholecystokinin) require vagal Cck1r/Cckar signaling to elicit satiation; high-fat diet reduces satiating capacity of these signals.
Title: Intraperitoneal CCK and fourth-intraventricular Apo AIV require both peripheral and NTS CCK1R to reduce food intake in male rats.

factors secondary to obesity and/or diabetes rather than impaired CCK-1 receptor signaling may contribute to altered CART expression
Title: Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats.

CCK-A receptors are located on the cell bodies of cholinergic interneurons in the corpus striatum.
Title: Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity.

Activation of duodenal PKC-delta leads to the stimulation of CCK release and activation of the CCK-A receptor signaling axis to lower glucose production in normal rats.
Title: Duodenal PKC-? and cholecystokinin signaling axis regulates glucose production.

The following Cckar gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cckar cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00613	NM_012688.3 Latest version!	Rattus norvegicus cholecystokinin A receptor (Cckar), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36115	XM_017599077.1 Latest version!	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36115	XM_008770188.2 Latest version!	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa58225	XM_017599078.1 Latest version!	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cckar ( NM_012688.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036820.1 Rattus norvegicus cholecystokinin A receptor (Cckar), mRNA.

Price & Availability↑

CloneID	ORa00613
Clone ID Related Accession (Same CDS sequence)	NM_012688.3
Accession Version	NM_012688.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	cholecystokinin receptor type A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M88096.1. On Aug 30, 2012 this sequence version replaced NM_012688.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M88096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689604, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCCAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATTGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036820.1
CDS	150..1484
Translation	MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP

Target ORF information:

RefSeq Version	NM_012688.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholecystokinin A receptor (Cckar), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012688.3

ORF Insert Sequence:

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCCAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATTGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cckar ( XM_008770188.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768410.1 Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36115
Clone ID Related Accession (Same CDS sequence)	XM_008770188.2 , XM_017599077.1
Accession Version	XM_008770188.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cholecystokinin receptor type A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008770188.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCTAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATCGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768410.1
CDS	346..1680
Translation	MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRASLSRYSYSHMSTSAPPP

Target ORF information:

RefSeq Version	XM_008770188.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770188.2

ORF Insert Sequence:

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCTAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATCGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cckar ( XM_017599077.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454566.1 Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa36115
Clone ID Related Accession (Same CDS sequence)	XM_008770188.2 , XM_017599077.1
Accession Version	XM_017599077.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cholecystokinin receptor type A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCTAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATCGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454566.1
CDS	235..1569
Translation	MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRASLSRYSYSHMSTSAPPP

Target ORF information:

RefSeq Version	XM_017599077.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599077.1

ORF Insert Sequence:

ATGAGCCATT CACCAGCTCG CCAGCACTTG GTAGAAAGCA GCAGGATGGA CGTGGTCGAC 
AGCCTTCTTA TGAATGGGAG CAACATCACT CCCCCCTGTG AACTCGGACT GGAAAATGAG 
ACGCTTTTCT GCTTGGATCA ACCTCAACCT TCAAAAGAGT GGCAGTCTGC ACTGCAGATT 
CTCCTGTACT CCATCATATT CCTTCTCAGT GTGCTGGGGA ACACGCTGGT TATAACGGTG 
CTGATTCGAA ACAAGAGGAT GCGGACGGTC ACCAACATCT TCCTGCTGTC CCTGGCTGTC 
AGTGACCTCA TGCTCTGCCT CTTCTGCATG CCGTTCAACC TCATCCCCAA CCTGCTCAAG 
GATTTCATCT TCGGAAGTGC CGTGTGCAAG ACTACCACCT ACTTCATGGG CACTTCCGTG 
AGCGTTTCCA CCTTCAACCT GGTAGCCATC TCTCTGGAGA GATATGGCGC CATCTGCAGA 
CCCCTACAGT CCCGCGTCTG GCAAACAAAG TCCCATGCTT TGAAGGTCAT CGCTGCCACC 
TGGTGCCTCT CCTTTACCAT CATGACTCCG TACCCCATTT ACAGCAACTT GGTGCCTTTT 
ACTAAAAATA ATAACCAGAC GGCGAACATG TGCCGCTTCC TGTTGCCAAG TGACGCTATG 
CAGCAGTCCT GGCAAACATT CCTGCTACTC ATCCTCTTTC TTCTCCCTGG GATTGTGATG 
GTGGTGGCCT ACGGGTTGAT CTCTCTGGAA CTCTACCAAG GAATCAAATT TGATGCCAGC 
CAGAAGAAAT CTGCTAAAGA GAAGAAGCCG AGCACTGGCA GCAGCACCCG ATATGAGGAT 
AGTGATGGCT GTTACTTGCA GAAGTCCCGG CCCCCGAGGA AGCTGGAGCT TCAGCAGCTG 
TCTAGCGGCA GCGGTGGCAG CAGACTCAAC CGGATCAGGA GCAGCAGTTC AGCTGCCAAC 
CTGATAGCCA AGAAGCGCGT GATCCGCATG CTCATTGTCA TCGTGGTCCT CTTCTTCCTG 
TGCTGGATGC CCATCTTCAG CGCCAACGCC TGGCGGGCAT ATGACACGGT TTCTGCCGAG 
AAGCACCTCT CAGGGACTCC CATCTCCTTC ATCCTCCTCC TCTCCTACAC CTCCTCCTGT 
GTTAACCCCA TCATCTATTG CTTCATGAAC AAACGCTTTC GCCTGGGCTT CATGGCCACC 
TTCCCTTGTT GCCCGAATCC CGGTCCCCCA GGGGTGAGAG GAGAGGTGGG AGAGGAGGAG 
GATGGGAGGA CCATAAGGGC ATCGCTGTCC AGGTATTCCT ACAGCCACAT GAGCACCTCT 
GCTCCACCCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cckar ( XM_017599078.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454567.1 Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X3, mRNA.

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CloneID	ORa58225
Clone ID Related Accession (Same CDS sequence)	XM_017599078.1
Accession Version	XM_017599078.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cholecystokinin receptor type A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGACGG TCACCAACAT CTTCCTGCTG TCCCTGGCTG TCAGTGACCT CATGCTCTGC 
CTCTTCTGCA TGCCGTTCAA CCTCATCCCC AACCTGCTCA AGGATTTCAT CTTCGGAAGT 
GCCGTGTGCA AGACTACCAC CTACTTCATG GGCACTTCCG TGAGCGTTTC CACCTTCAAC 
CTGGTAGCCA TCTCTCTGGA GAGATATGGC GCCATCTGCA GACCCCTACA GTCCCGCGTC 
TGGCAAACAA AGTCCCATGC TTTGAAGGTC ATCGCTGCCA CCTGGTGCCT CTCCTTTACC 
ATCATGACTC CGTACCCCAT TTACAGCAAC TTGGTGCCTT TTACTAAAAA TAATAACCAG 
ACGGCGAACA TGTGCCGCTT CCTGTTGCCA AGTGACGCTA TGCAGCAGTC CTGGCAAACA 
TTCCTGCTAC TCATCCTCTT TCTTCTCCCT GGGATTGTGA TGGTGGTGGC CTACGGGTTG 
ATCTCTCTGG AACTCTACCA AGGAATCAAA TTTGATGCCA GCCAGAAGAA ATCTGCTAAA 
GAGAAGAAGC CGAGCACTGG CAGCAGCACC CGATATGAGG ATAGTGATGG CTGTTACTTG 
CAGAAGTCCC GGCCCCCGAG GAAGCTGGAG CTTCAGCAGC TGTCTAGCGG CAGCGGTGGC 
AGCAGACTCA ACCGGATCAG GAGCAGCAGT TCAGCTGCCA ACCTGATAGC CAAGAAGCGC 
GTGATCCGCA TGCTCATTGT CATCGTGGTC CTCTTCTTCC TGTGCTGGAT GCCCATCTTC 
AGCGCCAACG CCTGGCGGGC ATATGACACG GTTTCTGCCG AGAAGCACCT CTCAGGGACT 
CCCATCTCCT TCATCCTCCT CCTCTCCTAC ACCTCCTCCT GTGTTAACCC CATCATCTAT 
TGCTTCATGA ACAAACGCTT TCGCCTGGGC TTCATGGCCA CCTTCCCTTG TTGCCCGAAT 
CCCGGTCCCC CAGGGGTGAG AGGAGAGGTG GGAGAGGAGG AGGATGGGAG GACCATAAGG 
GCATCGCTGT CCAGGTATTC CTACAGCCAC ATGAGCACCT CTGCTCCACC CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454567.1
CDS	134..1210
Translation	MRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRASLSRYSYSHMSTSAPPP

Target ORF information:

RefSeq Version	XM_017599078.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholecystokinin A receptor (Cckar), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599078.1

ORF Insert Sequence:

ATGCGGACGG TCACCAACAT CTTCCTGCTG TCCCTGGCTG TCAGTGACCT CATGCTCTGC 
CTCTTCTGCA TGCCGTTCAA CCTCATCCCC AACCTGCTCA AGGATTTCAT CTTCGGAAGT 
GCCGTGTGCA AGACTACCAC CTACTTCATG GGCACTTCCG TGAGCGTTTC CACCTTCAAC 
CTGGTAGCCA TCTCTCTGGA GAGATATGGC GCCATCTGCA GACCCCTACA GTCCCGCGTC 
TGGCAAACAA AGTCCCATGC TTTGAAGGTC ATCGCTGCCA CCTGGTGCCT CTCCTTTACC 
ATCATGACTC CGTACCCCAT TTACAGCAAC TTGGTGCCTT TTACTAAAAA TAATAACCAG 
ACGGCGAACA TGTGCCGCTT CCTGTTGCCA AGTGACGCTA TGCAGCAGTC CTGGCAAACA 
TTCCTGCTAC TCATCCTCTT TCTTCTCCCT GGGATTGTGA TGGTGGTGGC CTACGGGTTG 
ATCTCTCTGG AACTCTACCA AGGAATCAAA TTTGATGCCA GCCAGAAGAA ATCTGCTAAA 
GAGAAGAAGC CGAGCACTGG CAGCAGCACC CGATATGAGG ATAGTGATGG CTGTTACTTG 
CAGAAGTCCC GGCCCCCGAG GAAGCTGGAG CTTCAGCAGC TGTCTAGCGG CAGCGGTGGC 
AGCAGACTCA ACCGGATCAG GAGCAGCAGT TCAGCTGCCA ACCTGATAGC CAAGAAGCGC 
GTGATCCGCA TGCTCATTGT CATCGTGGTC CTCTTCTTCC TGTGCTGGAT GCCCATCTTC 
AGCGCCAACG CCTGGCGGGC ATATGACACG GTTTCTGCCG AGAAGCACCT CTCAGGGACT 
CCCATCTCCT TCATCCTCCT CCTCTCCTAC ACCTCCTCCT GTGTTAACCC CATCATCTAT 
TGCTTCATGA ACAAACGCTT TCGCCTGGGC TTCATGGCCA CCTTCCCTTG TTGCCCGAAT 
CCCGGTCCCC CAGGGGTGAG AGGAGAGGTG GGAGAGGAGG AGGATGGGAG GACCATAAGG 
GCATCGCTGT CCAGGTATTC CTACAGCCAC ATGAGCACCT CTGCTCCACC CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.
The Journal of comparative neurology522(17)3817-33(2014 Dec)
Parks GS,Wang L,Wang Z,Civelli O

Intraperitoneal CCK and fourth-intraventricular Apo AIV require both peripheral and NTS CCK1R to reduce food intake in male rats.
Endocrinology155(5)1700-7(2014 May)
Lo CC,Davidson WS,Hibbard SK,Georgievsky M,Lee A,Tso P,Woods SC

Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats.
Journal of chemical neuroanatomy50-5175-84(2013 May)
Armbruszt S,Abraham H,Figler M,Kozicz T,Hajnal A

Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity.
Brain research bulletin89(5-6)177-84(2012 Dec)
Petkova-Kirova P,Giovannini MG,Kalfin R,Rakovska A

Duodenal PKC-? and cholecystokinin signaling axis regulates glucose production.
Diabetes60(12)3148-53(2011 Dec)
Breen DM,Yue JT,Rasmussen BA,Kokorovic A,Cheung GW,Lam TK

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Cckar cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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