Thy1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Thy1
Entrez Gene ID	24832
Full Name	Thy-1 cell surface antigen
Synonyms	CD7
General protein information	Preferred Names Thy-1 cell surface antigen Names thy-1 membrane glycoprotein CD90 Thy-1 protein Thymus cell surface antigen thy-1 antigen thy-1 glycoprotein thymus cell antigen 1, theta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q22
Summary	cell surface glycoprotein antigen [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017595476.1	XP_017450965.1	thy-1 membrane glycoprotein isoform X1
NM_012673.2	NP_036805.1	thy-1 membrane glycoprotein preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	THY1	NP_006279.2
Xenopus tropicalis (tropical clawed frog)	thy1	XP_004916102.1
Canis lupus familiaris (dog)	THY1	XP_849699.1
Mus musculus (house mouse)	Thy1	NP_033408.1
Gallus gallus (chicken)	THY1	NP_989712.1
Pan troglodytes (chimpanzee)	THY1	XP_003313415.1
Bos taurus (cattle)	THY1	NP_001029937.1
	THY1	NP_001036103.1
Rattus norvegicus (Norway rat)	Thy1	NP_036805.1

Gene Ontology
Bibliography

Related articles in PubMed

Therapeutic benefits of CD90-negative cardiac stromal cells in rats with a 30-day chronic infarct.
Shen D, Shen M, Liang H, Tang J, Wang B, Liu C, Wang P, Dong J, Li L, Zhang J, Caranasos TG
Journal of cellular and molecular medicine(2018 Jan)

Identification of THY1 as a novel thyrotrope marker and THY1 antibody-mediated thyrotrope isolation in the rat anterior pituitary gland.
Horiguchi K, Nakakura T, Yoshida S, Tsukada T, Kanno N, Hasegawa R, Takigami S, Ohsako S, Kato T, Kato Y
Biochemical and biophysical research communications480(2)273-279(2016 11)

Immunoexpressions of embryonic and nonembryonic stem cell markers (Nanog, Thy-1, c-kit) and cellular connections (connexin 43 and occludin) on testicular tissue in thyrotoxicosis rat model.
Oltulu F, Aktug H, Uysal A, Turgan N, Oktem G, Erbas O, Yavasoglu NK, Yavasoglu A
Human & experimental toxicology34(6)601-11(2015 Jun)

Disruption of THY-1 signaling in alveolar lipofibroblasts in experimentally induced congenital diaphragmatic hernia.
Friedmacher F, Hofmann AD, Takahashi H, Takahashi T, Gosemann JH, Puri P
Pediatric surgery international30(2)129-35(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

THY1 is expressed in the anterior lobe of the rat pituitary gland.THY1 is a novel specific marker of thyrotropes, which produce TSH.
Title: Identification of THY1 as a novel thyrotrope marker and THY1 antibody-mediated thyrotrope isolation in the rat anterior pituitary gland.

Immunoexpressions of embryonic and nonembryonic stem cell markers (Nanog, Thy-1, c-kit) and cellular connections (connexin 43 and occludin) on testicular tissue in thyrotoxicosis rat model
Title: Immunoexpressions of embryonic and nonembryonic stem cell markers (Nanog, Thy-1, c-kit) and cellular connections (connexin 43 and occludin) on testicular tissue in thyrotoxicosis rat model.

Thymocyte antigen 1 (Thy-1) is a highly expressed cell-surface protein in lung fibroblasts, which plays a key role in fetal alveolarization by coordinating the differentiation and lipid homeostasis of alveolar lipid containing fibroblasts.
Title: Disruption of THY-1 signaling in alveolar lipofibroblasts in experimentally induced congenital diaphragmatic hernia.

first report that Thy1 colocalizes and coimmunoprecipitates with a membrane-spanning protein in retina, that Thy1 complexes with an ion channel protein in any tissue, and that a GPI-anchored protein associates with an HCN channel subunit protein.
Title: Thy1 associates with the cation channel subunit HCN4 in adult rat retina.

Study is the first to demonstrate a functional link between alphavbeta3 integrin and P2X7 receptors, and to reveal an important, hitherto unanticipated, role for P2X7 in calcium-dependent signaling required for Thy-1-stimulated astrocyte adhesion.
Title: ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation.

The following Thy1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thy1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00586	NM_012673.2 Latest version!	Rattus norvegicus Thy-1 cell surface antigen (Thy1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa62321	XM_017595476.1 Latest version!	Rattus norvegicus Thy-1 cell surface antigen (Thy1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Thy1 ( NM_012673.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036805.1 Rattus norvegicus Thy-1 cell surface antigen (Thy1), mRNA.

Price & Availability↑

CloneID	ORa00586
Clone ID Related Accession (Same CDS sequence)	NM_012673.2
Accession Version	NM_012673.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Rattus norvegicus(Norway rat)
Product	thy-1 membrane glycoprotein preproprotein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB797376.1, X03150.1, CO561977.1 and CB741211.1. On Jun 13, 2010 this sequence version replaced NM_012673.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CF975746.1, FQ098963.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAACCCAG TCATCAGCAT CACTCTCCTG CTTTCAGTCT TGCAGATGTC CCGAGGACAG 
AGGGTGATCA GCCTGACAGC CTGCCTGGTG AACCAGAACC TTCGACTGGA CTGCCGTCAT 
GAGAATAACA CCAACTTGCC CATCCAGCAT GAGTTCAGCC TGACCCGAGA GAAGAAGAAG 
CACGTGCTGT CAGGCACCCT GGGGGTTCCC GAGCACACTT ACCGCTCCCG CGTCAACCTT 
TTCAGTGACC GCTTTATCAA GGTCCTTACT CTAGCCAACT TCACCACCAA GGATGAGGGC 
GACTACATGT GTGAACTTCG AGTCTCGGGC CAGAATCCCA CAAGCTCCAA TAAAACTATC 
AATGTGATCA GAGACAAGCT GGTCAAGTGT GGTGGCATAA GCCTGCTGGT TCAAAACACT 
TCCTGGCTGC TGCTGCTCCT GCTTTCCCTC TCCTTCCTCC AAGCCACGGA CTTCATTTCT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036805.1
CDS	95..580
Translation	MNPVISITLLLSVLQMSRGQRVISLTACLVNQNLRLDCRHENNTNLPIQHEFSLTREKKKHVLSGTLGVPEHTYRSRVNLFSDRFIKVLTLANFTTKDEGDYMCELRVSGQNPTSSNKTINVIRDKLVKCGGISLLVQNTSWLLLLLLSLSFLQATDFISL

Target ORF information:

RefSeq Version	NM_012673.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Thy-1 cell surface antigen (Thy1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012673.2

ORF Insert Sequence:

ATGAACCCAG TCATCAGCAT CACTCTCCTG CTTTCAGTCT TGCAGATGTC CCGAGGACAG 
AGGGTGATCA GCCTGACAGC CTGCCTGGTG AACCAGAACC TTCGACTGGA CTGCCGTCAT 
GAGAATAACA CCAACTTGCC CATCCAGCAT GAGTTCAGCC TGACCCGAGA GAAGAAGAAG 
CACGTGCTGT CAGGCACCCT GGGGGTTCCC GAGCACACTT ACCGCTCCCG CGTCAACCTT 
TTCAGTGACC GCTTTATCAA GGTCCTTACT CTAGCCAACT TCACCACCAA GGATGAGGGC 
GACTACATGT GTGAACTTCG AGTCTCGGGC CAGAATCCCA CAAGCTCCAA TAAAACTATC 
AATGTGATCA GAGACAAGCT GGTCAAGTGT GGTGGCATAA GCCTGCTGGT TCAAAACACT 
TCCTGGCTGC TGCTGCTCCT GCTTTCCCTC TCCTTCCTCC AAGCCACGGA CTTCATTTCT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thy1 ( XM_017595476.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450965.1 Rattus norvegicus Thy-1 cell surface antigen (Thy1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62321
Clone ID Related Accession (Same CDS sequence)	XM_017595476.1
Accession Version	XM_017595476.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	thy-1 membrane glycoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGACA TCGAGGACAG CCTTTGGTTC TGCTTTCCAC CCAGAGGTCC CCAAGCTCAG 
ATCGCCTTAG TGGTGAGAAT AGAGGGAGGA GGTGGGTGGC AGGCTGGAGG GAGTCTCCGC 
CGGGTGACCT CGTGGCTGGC TGGGTGCGGG GCACCGCAGA CCCAGGACGG AGCTATTGGC 
ACCATGAACC CAGTCATCAG CATCACTCTC CTGCTTTCAG TCTTGCAGAT GTCCCGAGGA 
CAGAGGGTGA TCAGCCTGAC AGCCTGCCTG GTGAACCAGA ACCTTCGACT GGACTGCCGT 
CATGAGAATA ACACCAACTT GCCCATCCAG CATGAGTTCA GCCTGACCCG AGAGAAGAAG 
AAGCACGTGC TGTCAGGCAC CCTGGGGGTT CCCGAGCACA CTTACCGCTC CCGCGTCAAC 
CTTTTCAGTG ACCGCTTTAT CAAGGTCCTT ACTCTAGCCA ACTTCACCAC CAAGGATGAG 
GGCGACTACA TGTGTGAACT TCGAGTCTCG GGCCAGAATC CCACAAGCTC CAATAAAACT 
ATCAATGTGA TCAGAGACAA GCTGGTCAAG TGTGGTGGCA TAAGCCTGCT GGTTCAAAAC 
ACTTCCTGGC TGCTGCTGCT CCTGCTTTCC CTCTCCTTCC TCCAAGCCAC GGACTTCATT 
TCTCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450965.1
CDS	227..895
Translation	MKDIEDSLWFCFPPRGPQAQIALVVRIEGGGGWQAGGSLRRVTSWLAGCGAPQTQDGAIGTMNPVISITLLLSVLQMSRGQRVISLTACLVNQNLRLDCRHENNTNLPIQHEFSLTREKKKHVLSGTLGVPEHTYRSRVNLFSDRFIKVLTLANFTTKDEGDYMCELRVSGQNPTSSNKTINVIRDKLVKCGGISLLVQNTSWLLLLLLSLSFLQATDFISL

Target ORF information:

RefSeq Version	XM_017595476.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Thy-1 cell surface antigen (Thy1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595476.1

ORF Insert Sequence:

ATGAAGGACA TCGAGGACAG CCTTTGGTTC TGCTTTCCAC CCAGAGGTCC CCAAGCTCAG 
ATCGCCTTAG TGGTGAGAAT AGAGGGAGGA GGTGGGTGGC AGGCTGGAGG GAGTCTCCGC 
CGGGTGACCT CGTGGCTGGC TGGGTGCGGG GCACCGCAGA CCCAGGACGG AGCTATTGGC 
ACCATGAACC CAGTCATCAG CATCACTCTC CTGCTTTCAG TCTTGCAGAT GTCCCGAGGA 
CAGAGGGTGA TCAGCCTGAC AGCCTGCCTG GTGAACCAGA ACCTTCGACT GGACTGCCGT 
CATGAGAATA ACACCAACTT GCCCATCCAG CATGAGTTCA GCCTGACCCG AGAGAAGAAG 
AAGCACGTGC TGTCAGGCAC CCTGGGGGTT CCCGAGCACA CTTACCGCTC CCGCGTCAAC 
CTTTTCAGTG ACCGCTTTAT CAAGGTCCTT ACTCTAGCCA ACTTCACCAC CAAGGATGAG 
GGCGACTACA TGTGTGAACT TCGAGTCTCG GGCCAGAATC CCACAAGCTC CAATAAAACT 
ATCAATGTGA TCAGAGACAA GCTGGTCAAG TGTGGTGGCA TAAGCCTGCT GGTTCAAAAC 
ACTTCCTGGC TGCTGCTGCT CCTGCTTTCC CTCTCCTTCC TCCAAGCCAC GGACTTCATT 
TCTCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Therapeutic benefits of CD90-negative cardiac stromal cells in rats with a 30-day chronic infarct.
Journal of cellular and molecular medicine(2018 Jan)
Shen D,Shen M,Liang H,Tang J,Wang B,Liu C,Wang P,Dong J,Li L,Zhang J,Caranasos TG

Identification of THY1 as a novel thyrotrope marker and THY1 antibody-mediated thyrotrope isolation in the rat anterior pituitary gland.
Biochemical and biophysical research communications480(2)273-279(2016 11)
Horiguchi K,Nakakura T,Yoshida S,Tsukada T,Kanno N,Hasegawa R,Takigami S,Ohsako S,Kato T,Kato Y

Immunoexpressions of embryonic and nonembryonic stem cell markers (Nanog, Thy-1, c-kit) and cellular connections (connexin 43 and occludin) on testicular tissue in thyrotoxicosis rat model.
Human & experimental toxicology34(6)601-11(2015 Jun)
Oltulu F,Aktug H,Uysal A,Turgan N,Oktem G,Erbas O,Yavasoglu NK,Yavasoglu A

Disruption of THY-1 signaling in alveolar lipofibroblasts in experimentally induced congenital diaphragmatic hernia.
Pediatric surgery international30(2)129-35(2014 Feb)
Friedmacher F,Hofmann AD,Takahashi H,Takahashi T,Gosemann JH,Puri P

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Thy1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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