gRNAs
The following Tg gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tg cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12635 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001270784.1 | |
| Accession Version | NM_001270784.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-22 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | thyroglobulin isoform 3 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058267.1. Transcript Variant: This variant (3) consists of only the first five exons plus an alternate 3' exon compared to variant 1. The resulting isoform (3) has a much shorter and distinct C-terminus compared to isoform 1. This variant has been described in PMID:2325666. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M35965.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001257713.1 |
| CDS | 41..772 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001270784.1 |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa12620 | |
| Clone ID Related Accession (Same CDS sequence) | NM_030988.2 | |
| Accession Version | NM_030988.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 8307bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-22 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | thyroglobulin isoform 1 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058267.1, AABR07058268.1, AABR07073320.1 and AC120745.5. On Jul 31, 2012 this sequence version replaced NM_030988.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB035201.1, AB679745.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_112250.2 |
| CDS | 41..8347 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_030988.2 |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa12621 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001270783.1 | |
| Accession Version | NM_001270783.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 8163bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-22 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | thyroglobulin isoform 2 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058267.1, AABR07058268.1, AABR07073320.1 and AC120745.5. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB682739.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001257712.1 |
| CDS | 41..8203 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001270783.1 |
1 | ATGATGACCT TGGTCTTGTG GGTCTCGACT TTGTTGAGCT CAGTCTGCCT GGTAGCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Follicular thyroglobulin induces cathepsin H expression and activity in thyrocytes. |
Sterol regulatory element-binding proteins are transcriptional regulators of the thyroglobulin gene in thyroid cells. |
Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line. |
A novel mutation in the thyroglobulin gene that causes goiter and dwarfism in Wistar Hannover GALAS rats. |
Thyroglobulin increases thyroid cell proliferation via the suppression of specific microRNAs. |
