Tmbim6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmbim6
Entrez Gene ID	24822
Full Name	transmembrane BAX inhibitor motif containing 6
Synonyms	Ab1-011,Ac1-149,Cc1-27,Tegt
General protein information	Preferred Names transmembrane BAX inhibitor motif containing 6 Names bax inhibitor 1 BI-1 Bax inhibitor-1 testis enhanced gene transcript testis-enhanced gene transcript protein transmembrane BAX inhibitor motif-containing protein 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36
Summary	Suppressor of apoptosis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594666.1	XP_017450155.1	bax inhibitor 1 isoform X1
NM_019381.2	NP_062254.2	bax inhibitor 1
XM_006257323.3	XP_006257385.1	bax inhibitor 1 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tmbim6	NP_001164506.1
Xenopus tropicalis (tropical clawed frog)	tmbim6	NP_001017100.1
Bos taurus (cattle)	TMBIM6	NP_001069882.1
Danio rerio (zebrafish)	tegt	XP_005169303.1
Arabidopsis thaliana (thale cress)	BI1	NP_199523.1
Homo sapiens (human)	TMBIM6	NP_001092046.1
Pan troglodytes (chimpanzee)	TMBIM6	NP_001233339.1
	TMBIM6	XP_002798609.1
Rattus norvegicus (Norway rat)	Tmbim6	NP_062254.2
Drosophila melanogaster (fruit fly)	BI-1	NP_648205.1
Canis lupus familiaris (dog)	TMBIM6	NP_001239328.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005775	XP_315790.3
Oryza sativa (rice)	Os02g0125300	NP_001045745.1

Gene Ontology
Bibliography

Related articles in PubMed

[Over-expressed Bax inhibitor 1 (BI-1) inhibits apoptosis of hippocampal neurons via endoplasmic reticulum IRE1-JNK pathway in rats with subarachnoid hemorrhage].
Liu J, Zhou S, Qian X, Zhang Y, Zhao J
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology33(10)1316-1322(2017 Oct)

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
Urresti J, Ruiz-Meana M, Coccia E, Ar?valo JC, Castellano J, Fern?ndez-Sanz C, Galenkamp KM, Planells-Ferrer L, Moubarak RS, Llecha-Cano N, Reix S, Garc?a-Dorado D, Barneda-Zahonero B, Comella JX
The Journal of biological chemistry291(3)1221-34(2016 Jan)

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis.
Rojas-Rivera D, Armis?n R, Colombo A, Mart?nez G, Eguiguren AL, D?az A, Kiviluoto S, Rodr?guez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C
Cell death and differentiation19(6)1013-26(2012 Jun)

Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury.
Krajewska M, Xu L, Xu W, Krajewski S, Kress CL, Cui J, Yang L, Irie F, Yamaguchi Y, Lipton SA, Reed JC
Brain research1370227-37(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that Bax inhibitor-1 overexpression in the endoplasmic reticulum is protective in neurons.
Title: Bax inhibitor-1 protects neurons from oxygen-glucose deprivation.

The following Tmbim6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmbim6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04618	NM_019381.2 Latest version!	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa04618	XM_006257323.3 Latest version!	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa61901	XM_017594666.1 Latest version!	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmbim6 ( NM_019381.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062254.2 Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), mRNA.

Price & Availability↑

CloneID	ORa04618
Clone ID Related Accession (Same CDS sequence)	NM_019381.2 , XM_006257323.3
Accession Version	NM_019381.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	bax inhibitor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC058478.1. On or before Jan 28, 2007 this sequence version replaced XM_576343.2, XM_001063712.1, NM_019381.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058478.1, FQ218441.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG GACAAAAAGA AAGAGAAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062254.2
CDS	83..796
Translation	MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGALALMICLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAINPSILPTAFMGTAMIFTCFSLSALYARRRSYLFLGGILMSAMSLMFVSSLGNLFFGSIWLFQANLYMGLLVMCGFVLFDTQLIIEKAEHGDKDYIWHCIDLFLDFVTLFRKLMLILAFNEKDKKKEKK

Target ORF information:

RefSeq Version	NM_019381.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019381.2

ORF Insert Sequence:

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG GACAAAAAGA AAGAGAAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmbim6 ( XM_006257323.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006257385.1 Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa04618
Clone ID Related Accession (Same CDS sequence)	NM_019381.2 , XM_006257323.3
Accession Version	XM_006257323.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bax inhibitor 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006257323.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG GACAAAAAGA AAGAGAAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006257385.1
CDS	650..1363
Translation	MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGALALMICLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAINPSILPTAFMGTAMIFTCFSLSALYARRRSYLFLGGILMSAMSLMFVSSLGNLFFGSIWLFQANLYMGLLVMCGFVLFDTQLIIEKAEHGDKDYIWHCIDLFLDFVTLFRKLMLILAFNEKDKKKEKK

Target ORF information:

RefSeq Version	XM_006257323.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006257323.3

ORF Insert Sequence:

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG GACAAAAAGA AAGAGAAGAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmbim6 ( XM_017594666.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450155.1 Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61901
Clone ID Related Accession (Same CDS sequence)	XM_017594666.1
Accession Version	XM_017594666.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bax inhibitor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG AAGCCCATTG ACCAGACTGT GGGCCATCTT 
AGTCTGCATG GAGAGGTGGC AACCGGAGTG GTTGTGGCCC TGGCTACCAA GCCCCTGACA 
GCCCGTTACC AGGAGGATGG TGGTTTTGAC TTTCTTCACT CAAAACCAGT GCAGTTGACA 
CAGTGGCTGC TGGTTCACTG TCCCATGAAA CTGCTTCTGG TGTGGTGCGC CCAGAGCGAC 
ATCTTGCCAC CCTGTTTGCC TGGTGCCTCC CCTGGCTCGA GCTTACAACC TGAGGGACGG 
CAGCAGCTCT CCAGAAAAAT GATGCCACGA GGCCTCAGGA CCCGACTGAG TTCCACCTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450155.1
CDS	146..1168
Translation	MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGALALMICLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAINPSILPTAFMGTAMIFTCFSLSALYARRRSYLFLGGILMSAMSLMFVSSLGNLFFGSIWLFQANLYMGLLVMCGFVLFDTQLIIEKAEHGDKDYIWHCIDLFLDFVTLFRKLMLILAFNEKKPIDQTVGHLSLHGEVATGVVVALATKPLTARYQEDGGFDFLHSKPVQLTQWLLVHCPMKLLLVWCAQSDILPPCLPGASPGSSLQPEGRQQLSRKMMPRGLRTRLSSTS

Target ORF information:

RefSeq Version	XM_017594666.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594666.1

ORF Insert Sequence:

ATGAATATAT TTGATCGGAA GATCAACTTT GATGCCCTCT TAAAATTTTC CCACATAACT 
CCCTCCACAC AGCAGCACCT AAAGAAGGTC TATGCCAGTT TTGCACTGTG CATGTTTGTG 
GCAGCAGCAG GGGCCTATGT CCATGTGGTC ACACGTTTCA TCCAGGCTGG CCTGCTCTCT 
GCCCTGGGCG CCCTGGCCTT GATGATTTGC CTGATGGCCA CACCTCACAG CCATGAGACG 
GAGCAGAAGA GGCTGGGACT GCTCGCTGGC TTCGCCTTCC TTACAGGAGT TGGCCTGGGA 
CCTGCCCTGG AGCTGTGCAT TGCCATCAAC CCCAGCATCC TCCCCACGGC CTTCATGGGC 
ACGGCCATGA TCTTCACCTG CTTCAGCCTG AGTGCCCTCT ACGCCAGGCG CCGGAGTTAC 
CTCTTTTTGG GAGGTATCTT GATGTCAGCC ATGAGCCTCA TGTTCGTGTC CTCTCTGGGG 
AACCTTTTCT TTGGATCCAT TTGGCTGTTC CAGGCAAACC TGTACATGGG GCTGCTGGTC 
ATGTGCGGCT TTGTCCTCTT CGACACTCAG CTCATTATTG AAAAGGCTGA ACACGGAGAC 
AAGGATTACA TCTGGCACTG CATTGACCTC TTCTTGGACT TCGTTACACT CTTCAGGAAG 
CTCATGCTGA TCTTGGCCTT CAATGAGAAG AAGCCCATTG ACCAGACTGT GGGCCATCTT 
AGTCTGCATG GAGAGGTGGC AACCGGAGTG GTTGTGGCCC TGGCTACCAA GCCCCTGACA 
GCCCGTTACC AGGAGGATGG TGGTTTTGAC TTTCTTCACT CAAAACCAGT GCAGTTGACA 
CAGTGGCTGC TGGTTCACTG TCCCATGAAA CTGCTTCTGG TGTGGTGCGC CCAGAGCGAC 
ATCTTGCCAC CCTGTTTGCC TGGTGCCTCC CCTGGCTCGA GCTTACAACC TGAGGGACGG 
CAGCAGCTCT CCAGAAAAAT GATGCCACGA GGCCTCAGGA CCCGACTGAG TTCCACCTCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Over-expressed Bax inhibitor 1 (BI-1) inhibits apoptosis of hippocampal neurons via endoplasmic reticulum IRE1-JNK pathway in rats with subarachnoid hemorrhage].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology33(10)1316-1322(2017 Oct)
Liu J,Zhou S,Qian X,Zhang Y,Zhao J

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
The Journal of biological chemistry291(3)1221-34(2016 Jan)
Urresti J,Ruiz-Meana M,Coccia E,Ar?valo JC,Castellano J,Fern?ndez-Sanz C,Galenkamp KM,Planells-Ferrer L,Moubarak RS,Llecha-Cano N,Reix S,Garc?a-Dorado D,Barneda-Zahonero B,Comella JX

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis.
Cell death and differentiation19(6)1013-26(2012 Jun)
Rojas-Rivera D,Armis?n R,Colombo A,Mart?nez G,Eguiguren AL,D?az A,Kiviluoto S,Rodr?guez D,Patron M,Rizzuto R,Bultynck G,Concha ML,Sierralta J,Stutzin A,Hetz C

Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury.
Brain research1370227-37(2011 Jan)
Krajewska M,Xu L,Xu W,Krajewski S,Kress CL,Cui J,Yang L,Irie F,Yamaguchi Y,Lipton SA,Reed JC

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Tmbim6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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