Pcyox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pcyox1
Entrez Gene ID	246302
Full Name	prenylcysteine oxidase 1
Synonyms	Clp55
General protein information	Preferred Names prenylcysteine oxidase 1 Names prenylcysteine oxidase chloride ion pump-associated 55 kDa protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34
Summary	a Cl(-) pump subunit; involved in outwardly directed Cl(-) transport [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_145085.2	NP_659553.1	prenylcysteine oxidase precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PCYOX1	NP_001098944.1
Arabidopsis thaliana (thale cress)	FCLY	NP_201196.1
Xenopus tropicalis (tropical clawed frog)	pcyox1	NP_001016302.1
Mus musculus (house mouse)	Pcyox1	NP_080099.1
Rattus norvegicus (Norway rat)	Pcyox1	NP_659553.1
Gallus gallus (chicken)	PCYOX1	XP_423959.2
Danio rerio (zebrafish)	pcyox1	NP_001017626.1
Oryza sativa (rice)	Os04g0692800	NP_001054372.2
Homo sapiens (human)	PCYOX1	NP_057381.3
Pan troglodytes (chimpanzee)	PCYOX1	XP_003309143.1
	LOC710068	XP_001098650.2
Canis lupus familiaris (dog)	LOC481418	XP_538538.2

Gene Ontology
Bibliography

Related articles in PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF.
Mancone C, Amicone L, Fimia GM, Bravo E, Piacentini M, Tripodi M, Alonzi T
Proteomics7(1)143-54(2007 Jan)

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver.
Beigneux A, Withycombe SK, Digits JA, Tschantz WR, Weinbaum CA, Griffey SM, Bergo M, Casey PJ, Young SG
The Journal of biological chemistry277(41)38358-63(2002 Oct)

Molecular cloning and characterization of the Cl(-) pump-associated 55-kDa protein in rat brain.
Kitagawa K, Yagyu K, Yamamoto A, Hattori N, Omori K, Zeng XT, Inagaki C
Biochemical and biophysical research communications289(2)363-71(2001 Nov)

Cloning, expression, and cellular localization of a human prenylcysteine lyase.
Tschantz WR, Zhang L, Casey PJ
The Journal of biological chemistry274(50)35802-8(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pcyox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pcyox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02540	NM_145085.2 Latest version!	Rattus norvegicus prenylcysteine oxidase 1 (Pcyox1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pcyox1 ( NM_145085.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_659553.1 Rattus norvegicus prenylcysteine oxidase 1 (Pcyox1), mRNA.

Price & Availability↑

CloneID	ORa02540
Clone ID Related Accession (Same CDS sequence)	NM_145085.2
Accession Version	NM_145085.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	prenylcysteine oxidase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078719.1. On Jun 10, 2007 this sequence version replaced NM_145085.1. ##Evidence-Data-START## Transcript exon combination :: BC078719.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCGCT TCGCCGCTAC GCTGGTGGGC TCGCTGTTCG GTCTGGGGCT GCTGCTGTGT 
GGTCTAGGCA GGCTGGCGAG CGCCGAGCCC CGGGCCCCTC CGGAAAAGAT CGCAATAGTT 
GGTGCTGGAA TCGGTGGTAC TTCCTCGGCC TATTATCTTC GGAAGAAATT TGGGAAGGAC 
GTGAAGATTG ATGTGTTTGA AAGAGAAGAA ATCGGGGGCC GTTTGGCTAC TTTGAAGGTG 
CAAGGTCATG ACTACGAAGC AGGGGGTTCA GTCATTCACC CTCTAAATTT GCACATGAAG 
CGATTTGTCA AAGAGCTGGG TCTCTCCAGT GTGCCCGCTT CAGGTGGCCT GGTGGGAGTG 
TACAATGGGA AGTCTCTGGT GTTTGAGGAG AGCAGCTGGT TTATAATCAA CGTGATTAAG 
CTGGTGTGGC GCTATGGATT TCAGTCCCTG AGAATGCACA TGTGGGTAGA AGACCTGCTC 
GACAAGTTCA TGAGGATCTA TCGTTACCAG TCCCATGACT ATGCCTTCAG TAGCGTAGAA 
AAGTTGATGT ACGCCATTGG AGGGGATGAC TATGTCAGAC TGCTCAACCA AACTCTCCGT 
GAAAACCTGA AGAAAGCAGG CTTCTCTGAG ACGTTCCTCA ATGAGATGAT CGCTCCTGTC 
ATGAAGGTCA ATTTTGGCCA AAGCACTGAC CTCAATGCTT TTGTGGGTGC AGTATCAATG 
ACTGCTGCTG ATTCCAACCT TTGGGCAGTG GAAGGTGGTA ATAAAGTTGT TTGCTCAGGG 
CTCCTTCAGG CCTCTAACAG CAATCTTATA TCTGGCTCTG TAATGTCAAT AGAGAAGACA 
AGGACCAAGC AGACAGGAAC CCCCCCGAAG ATGTATGAAG TGGTTTATAA AACAGGATCT 
GAGATCCATT CTGACTTCTA TGACATTGTC CTTGTGGCTG CCCCATTGAA TCGGAAGATG 
TCCAACATAA CCTTCCGAAA TTTTGATCCC CCCATCGAGG AATTCAATGA CCCATATCAA 
CAGCTCGTGA CAACTCTCAT CAAAGGAGAG CTCAATTCTA CCCTCTTCAG CTCCAGGCAC 
AAGGATCAGT TCGGCCTGTC TGCGATTCTT GTCACTGATG ACTCAGATAT GTTTATCAAC 
AGCCTGTCCA TTGTGGCCTC TGTAAGTCAT AAGGAGGGTC CCCCACCGGC AGTGGATGGC 
ATGCATGTGT GGAAGACCTT CTCCAAGGAC ATTCTCACCA AAGAACAAAT CTCAAAGCTC 
TTCCTGTCCT ACGATTATGC TGTGCGGAAG CCGTGGCTGT CCTACCCTTA CTACAATCCT 
CCTCAGAAGT GTCCCTCCAT TATCCTCCAT GACCGGCTCT ATTACCTCAA TGGCATCGAG 
TTTGCTGCCA GCTGCATGGA GATGAGTGCC ATCGCTGGCT ACAACGCAGC GCTCCTTGCC 
TACCACCGTT GGAACGGCAA TGAGGACATG ATCGATCAGG ACGACCTGTA TGAAAAGCTT 
AAGACAGAAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659553.1
CDS	41..1555
Translation	MGRFAATLVGSLFGLGLLLCGLGRLASAEPRAPPEKIAIVGAGIGGTSSAYYLRKKFGKDVKIDVFEREEIGGRLATLKVQGHDYEAGGSVIHPLNLHMKRFVKELGLSSVPASGGLVGVYNGKSLVFEESSWFIINVIKLVWRYGFQSLRMHMWVEDLLDKFMRIYRYQSHDYAFSSVEKLMYAIGGDDYVRLLNQTLRENLKKAGFSETFLNEMIAPVMKVNFGQSTDLNAFVGAVSMTAADSNLWAVEGGNKVVCSGLLQASNSNLISGSVMSIEKTRTKQTGTPPKMYEVVYKTGSEIHSDFYDIVLVAAPLNRKMSNITFRNFDPPIEEFNDPYQQLVTTLIKGELNSTLFSSRHKDQFGLSAILVTDDSDMFINSLSIVASVSHKEGPPPAVDGMHVWKTFSKDILTKEQISKLFLSYDYAVRKPWLSYPYYNPPQKCPSIILHDRLYYLNGIEFAASCMEMSAIAGYNAALLAYHRWNGNEDMIDQDDLYEKLKTEL

Target ORF information:

RefSeq Version	NM_145085.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus prenylcysteine oxidase 1 (Pcyox1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145085.2

ORF Insert Sequence:

ATGGGGCGCT TCGCCGCTAC GCTGGTGGGC TCGCTGTTCG GTCTGGGGCT GCTGCTGTGT 
GGTCTAGGCA GGCTGGCGAG CGCCGAGCCC CGGGCCCCTC CGGAAAAGAT CGCAATAGTT 
GGTGCTGGAA TCGGTGGTAC TTCCTCGGCC TATTATCTTC GGAAGAAATT TGGGAAGGAC 
GTGAAGATTG ATGTGTTTGA AAGAGAAGAA ATCGGGGGCC GTTTGGCTAC TTTGAAGGTG 
CAAGGTCATG ACTACGAAGC AGGGGGTTCA GTCATTCACC CTCTAAATTT GCACATGAAG 
CGATTTGTCA AAGAGCTGGG TCTCTCCAGT GTGCCCGCTT CAGGTGGCCT GGTGGGAGTG 
TACAATGGGA AGTCTCTGGT GTTTGAGGAG AGCAGCTGGT TTATAATCAA CGTGATTAAG 
CTGGTGTGGC GCTATGGATT TCAGTCCCTG AGAATGCACA TGTGGGTAGA AGACCTGCTC 
GACAAGTTCA TGAGGATCTA TCGTTACCAG TCCCATGACT ATGCCTTCAG TAGCGTAGAA 
AAGTTGATGT ACGCCATTGG AGGGGATGAC TATGTCAGAC TGCTCAACCA AACTCTCCGT 
GAAAACCTGA AGAAAGCAGG CTTCTCTGAG ACGTTCCTCA ATGAGATGAT CGCTCCTGTC 
ATGAAGGTCA ATTTTGGCCA AAGCACTGAC CTCAATGCTT TTGTGGGTGC AGTATCAATG 
ACTGCTGCTG ATTCCAACCT TTGGGCAGTG GAAGGTGGTA ATAAAGTTGT TTGCTCAGGG 
CTCCTTCAGG CCTCTAACAG CAATCTTATA TCTGGCTCTG TAATGTCAAT AGAGAAGACA 
AGGACCAAGC AGACAGGAAC CCCCCCGAAG ATGTATGAAG TGGTTTATAA AACAGGATCT 
GAGATCCATT CTGACTTCTA TGACATTGTC CTTGTGGCTG CCCCATTGAA TCGGAAGATG 
TCCAACATAA CCTTCCGAAA TTTTGATCCC CCCATCGAGG AATTCAATGA CCCATATCAA 
CAGCTCGTGA CAACTCTCAT CAAAGGAGAG CTCAATTCTA CCCTCTTCAG CTCCAGGCAC 
AAGGATCAGT TCGGCCTGTC TGCGATTCTT GTCACTGATG ACTCAGATAT GTTTATCAAC 
AGCCTGTCCA TTGTGGCCTC TGTAAGTCAT AAGGAGGGTC CCCCACCGGC AGTGGATGGC 
ATGCATGTGT GGAAGACCTT CTCCAAGGAC ATTCTCACCA AAGAACAAAT CTCAAAGCTC 
TTCCTGTCCT ACGATTATGC TGTGCGGAAG CCGTGGCTGT CCTACCCTTA CTACAATCCT 
CCTCAGAAGT GTCCCTCCAT TATCCTCCAT GACCGGCTCT ATTACCTCAA TGGCATCGAG 
TTTGCTGCCA GCTGCATGGA GATGAGTGCC ATCGCTGGCT ACAACGCAGC GCTCCTTGCC 
TACCACCGTT GGAACGGCAA TGAGGACATG ATCGATCAGG ACGACCTGTA TGAAAAGCTT 
AAGACAGAAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF.
Proteomics7(1)143-54(2007 Jan)
Mancone C,Amicone L,Fimia GM,Bravo E,Piacentini M,Tripodi M,Alonzi T

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver.
The Journal of biological chemistry277(41)38358-63(2002 Oct)
Beigneux A,Withycombe SK,Digits JA,Tschantz WR,Weinbaum CA,Griffey SM,Bergo M,Casey PJ,Young SG

Molecular cloning and characterization of the Cl(-) pump-associated 55-kDa protein in rat brain.
Biochemical and biophysical research communications289(2)363-71(2001 Nov)
Kitagawa K,Yagyu K,Yamamoto A,Hattori N,Omori K,Zeng XT,Inagaki C

Cloning, expression, and cellular localization of a human prenylcysteine lyase.
The Journal of biological chemistry274(50)35802-8(1999 Dec)
Tschantz WR,Zhang L,Casey PJ