Optn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Optn
Entrez Gene ID	246294
Full Name	optineurin
Synonyms	Fip2
General protein information	Preferred Names optineurin Names optineurin 14.7K-interacting protein 2 FIP-2-like protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.3
Summary	an injury induced protein; human homolog may be linked to glaucoma [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017600454.1	XP_017455943.1	optineurin isoform X1
XM_006254264.3	XP_006254326.1	optineurin isoform X5
XM_017600455.1	XP_017455944.1	optineurin isoform X2
NM_145081.3	NP_659549.2	optineurin
XM_006254262.3	XP_006254324.1	optineurin isoform X3
XM_006254263.3	XP_006254325.1	optineurin isoform X4

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OPTN	XP_535187.4
Rattus norvegicus (Norway rat)	Optn	NP_659549.2
Danio rerio (zebrafish)	optn	NP_001093536.2
Xenopus tropicalis (tropical clawed frog)	optn	XP_004913094.1
	OPTN	NP_001028069.1
Bos taurus (cattle)	OPTN	NP_001029774.1
Mus musculus (house mouse)	Optn	NP_862896.1
Pan troglodytes (chimpanzee)	OPTN	XP_001139979.1
Homo sapiens (human)	OPTN	NP_068815.2
Gallus gallus (chicken)	OPTN	NP_989567.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of optineurin isolated from rat-injured dental pulp and the effects on inflammatory signals in normal rat kidney cells.
Senoo K, Yamashiro K, Yamamoto T, Myokai F, Kawamura M, Takashiba S
Odontology(2017 Aug)

A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.
Fifita JA, Williams KL, Sundaramoorthy V, Mccann EP, Nicholson GA, Atkin JD, Blair IP
Amyotrophic lateral sclerosis & frontotemporal degeneration18(1-2)126-133(2017 Feb)

Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity.
Hu X, Dai Y, Sun X
Molecular vision23447-456(2017)

From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models.
Wise JP Jr, Cannon J
Toxicological sciences : an official journal of the Society of Toxicology153(2)372-81(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

optineurin appears to play an important role in the maintenance of the podocyte Golgi complex.
Title: Optineurin associates with the podocyte Golgi complex to maintain its structure.

in a normal homeostatic situation, the turnover of endogenous optineurin involves mainly ubiquitin-proteasome pathway (UPP). When optineurin is up-regulated or mutated, the UPP function is compromised, and autophagy comes into play.
Title: Processing of optineurin in neuronal cells.

These results demonstrated that the two glaucoma genes, myocilin and optineurin, exhibited differential effects on neurite outgrowth.
Title: Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth.

mGLuR1a signaling is attenuated by the huntingtin-binding protein optineurin
Title: Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin.

The following Optn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Optn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02531	NM_145081.3 Latest version!	Rattus norvegicus optineurin (Optn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa38062	XM_006254263.3 Latest version!	Rattus norvegicus optineurin (Optn), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa38063	XM_006254264.3 Latest version!	Rattus norvegicus optineurin (Optn), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa38061	XM_006254262.3 Latest version!	Rattus norvegicus optineurin (Optn), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
ORa58994	XM_017600454.1 Latest version!	Rattus norvegicus optineurin (Optn), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
ORa58995	XM_017600455.1 Latest version!	Rattus norvegicus optineurin (Optn), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Optn ( NM_145081.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_659549.2 Rattus norvegicus optineurin (Optn), mRNA.

Price & Availability↑

CloneID	ORa02531
Clone ID Related Accession (Same CDS sequence)	NM_145081.3
Accession Version	NM_145081.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	optineurin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB069907.3. On Sep 30, 2003 this sequence version replaced NM_145081.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB069907.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAGGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GGAGCAACTG AAGAGGCAGG TGGAGCAGGA AGTGGAGCAT CTGAAGATCC AGGTGAGGCG 
CCTTCAGGCT TGAGAAAGCG GACCTTGCTG GGGCATTCGT CTCAGACTGC AGCTCAAGCT 
CAACTCCGGC GGCTCCTCAG AAGACTCCTT CGTGGAGACA GGATGACTGA AGGAGAGGCG 
GAAGGGGCAA TGAAGGAGAT GAGGAACAGC GCTGGACCCA CAAGGACAGA CTCCATCATC 
ATGGGCAAAT GTACAGAGGA CGCCAGGACT TGTGTGGAGT TTGAGGAACT GACTGTGAGC 
CAACTCCTGC TTTGCCTCAG GGAAGGAAAC CAAAAGGTGG AGAGACTCGA GATCGCGCTC 
AGAGAAGCCA AAGAAAGAAT TTCAGATTTT GAAAAGAAAG CAAACGGCCA TTCTGCGATT 
GAAACCCAGA CAGAGGGGAG CACACAAAAA GAAGAGGAGG ACAAAGACCC AGAGAGTGTG 
GGAATCGAAG TGGAAACTCT GAACGTTCAA GTGGCCTCTC TGTTTAAGGG GCTTCAAGAG 
GCGCACACAA AGCTCAGTGA GGCCGAGCTG ATGAAGAAGA GACTTCAAGA AAAGTGTCAG 
GCTCTGGAAA GGAAGAACTC TGCAACCCCA TCGGAGCTGA ATGAAAAGCA AGAGCTCGTT 
TACAGTAACT GGAAGTTAGA GCTGCAGGTG GAGAGCATGC GCTCGGAAAT CAAGATGGAG 
CAGGCCAAGA CAGAGGAGGA GAAATCCAGG TTAGCCACTC TTCAGGCAAC ACACGACAAG 
CTCCTTCAGG AACACAATAA AGCTCTGAGA ACAATTGAAG AACTAACCAA ACAACAGGCA 
GAAAAAGTGG ACAAGGTGCA GCTGCAGGAG CTCAGCGAGA AGCTGGAGCT GGCGGAGCAG 
GCTCTGGCGT CCAAGCAGCT CCAGATGGAT GAGATGAAGC AGACCATCGC CAAGCAGGAG 
GAGGACCTGG AGACCATGGC CGTCCTCAGG GCTCAGATGG AGGTGTACTG TTCAGATTTC 
CATGCTGAGA GGGCAGCAAG GGAGAAGATC CATGAGGAAA AGGAGCAGCT GGCCTTGCAG 
CTCGCCATTT TGCTGAAAGA GAACAATGAC TTTGAAGATG GAGGCAGTAG GCAGTCCTTG 
ATGGAAATGC AGTGCCGGCA CGGGGCGAGA ACCAGCGACT CTGACCAGCA GGCTTACCTG 
TTTCAAAGAG GAGCCAAGGA CATGAGCTGG CAGCATGGGC AGCAGCCCCG GAGTATTCCC 
ATTCACTCGT GCCCCAAGTG TGGGGAGGTC CTGCCGGACA TTGACACGCT TCAGATACAT 
GTGATGGACT GTATCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659549.2
CDS	27..1787
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTERQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVGATEEAGGAGSGASEDPGEAPSGLRKRTLLGHSSQTAAQAQLRRLLRRLLRGDRMTEGEAEGAMKEMRNSAGPTRTDSIIMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKGLQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNWKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGSRQSLMEMQCRHGARTSDSDQQAYLFQRGAKDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	NM_145081.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145081.3

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAGGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GGAGCAACTG AAGAGGCAGG TGGAGCAGGA AGTGGAGCAT CTGAAGATCC AGGTGAGGCG 
CCTTCAGGCT TGAGAAAGCG GACCTTGCTG GGGCATTCGT CTCAGACTGC AGCTCAAGCT 
CAACTCCGGC GGCTCCTCAG AAGACTCCTT CGTGGAGACA GGATGACTGA AGGAGAGGCG 
GAAGGGGCAA TGAAGGAGAT GAGGAACAGC GCTGGACCCA CAAGGACAGA CTCCATCATC 
ATGGGCAAAT GTACAGAGGA CGCCAGGACT TGTGTGGAGT TTGAGGAACT GACTGTGAGC 
CAACTCCTGC TTTGCCTCAG GGAAGGAAAC CAAAAGGTGG AGAGACTCGA GATCGCGCTC 
AGAGAAGCCA AAGAAAGAAT TTCAGATTTT GAAAAGAAAG CAAACGGCCA TTCTGCGATT 
GAAACCCAGA CAGAGGGGAG CACACAAAAA GAAGAGGAGG ACAAAGACCC AGAGAGTGTG 
GGAATCGAAG TGGAAACTCT GAACGTTCAA GTGGCCTCTC TGTTTAAGGG GCTTCAAGAG 
GCGCACACAA AGCTCAGTGA GGCCGAGCTG ATGAAGAAGA GACTTCAAGA AAAGTGTCAG 
GCTCTGGAAA GGAAGAACTC TGCAACCCCA TCGGAGCTGA ATGAAAAGCA AGAGCTCGTT 
TACAGTAACT GGAAGTTAGA GCTGCAGGTG GAGAGCATGC GCTCGGAAAT CAAGATGGAG 
CAGGCCAAGA CAGAGGAGGA GAAATCCAGG TTAGCCACTC TTCAGGCAAC ACACGACAAG 
CTCCTTCAGG AACACAATAA AGCTCTGAGA ACAATTGAAG AACTAACCAA ACAACAGGCA 
GAAAAAGTGG ACAAGGTGCA GCTGCAGGAG CTCAGCGAGA AGCTGGAGCT GGCGGAGCAG 
GCTCTGGCGT CCAAGCAGCT CCAGATGGAT GAGATGAAGC AGACCATCGC CAAGCAGGAG 
GAGGACCTGG AGACCATGGC CGTCCTCAGG GCTCAGATGG AGGTGTACTG TTCAGATTTC 
CATGCTGAGA GGGCAGCAAG GGAGAAGATC CATGAGGAAA AGGAGCAGCT GGCCTTGCAG 
CTCGCCATTT TGCTGAAAGA GAACAATGAC TTTGAAGATG GAGGCAGTAG GCAGTCCTTG 
ATGGAAATGC AGTGCCGGCA CGGGGCGAGA ACCAGCGACT CTGACCAGCA GGCTTACCTG 
TTTCAAAGAG GAGCCAAGGA CATGAGCTGG CAGCATGGGC AGCAGCCCCG GAGTATTCCC 
ATTCACTCGT GCCCCAAGTG TGGGGAGGTC CTGCCGGACA TTGACACGCT TCAGATACAT 
GTGATGGACT GTATCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Optn ( XM_006254263.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254325.1 Rattus norvegicus optineurin (Optn), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa38062
Clone ID Related Accession (Same CDS sequence)	XM_006254263.3
Accession Version	XM_006254263.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	optineurin isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254263.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGTAGGCA GTCCTTGATG 
GAAATGCAGT GCCGGCATGG GGCGAGAACC AGCGACTCTG ACCAGCAGGC TTACCTGTTT 
CAAAGAGGAG CCGAGGACAT GAGCTGGCAG CATGGGCAGC AGCCCCGGAG TATTCCCATT 
CACTCGTGCC CCAAGTGTGG GGAGGTCCTG CCGGACATTG ACACGCTTCA GATACATGTG 
ATGGACTGTA TCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254325.1
CDS	185..1942
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKNQVRRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGSRQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	XM_006254263.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254263.3

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGTAGGCA GTCCTTGATG 
GAAATGCAGT GCCGGCATGG GGCGAGAACC AGCGACTCTG ACCAGCAGGC TTACCTGTTT 
CAAAGAGGAG CCGAGGACAT GAGCTGGCAG CATGGGCAGC AGCCCCGGAG TATTCCCATT 
CACTCGTGCC CCAAGTGTGG GGAGGTCCTG CCGGACATTG ACACGCTTCA GATACATGTG 
ATGGACTGTA TCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Optn ( XM_006254264.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254326.1 Rattus norvegicus optineurin (Optn), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa38063
Clone ID Related Accession (Same CDS sequence)	XM_006254264.3
Accession Version	XM_006254264.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	optineurin isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254264.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGCAGTC CTTGATGGAA 
ATGCAGTGCC GGCATGGGGC GAGAACCAGC GACTCTGACC AGCAGGCTTA CCTGTTTCAA 
AGAGGAGCCG AGGACATGAG CTGGCAGCAT GGGCAGCAGC CCCGGAGTAT TCCCATTCAC 
TCGTGCCCCA AGTGTGGGGA GGTCCTGCCG GACATTGACA CGCTTCAGAT ACATGTGATG 
GACTGTATCA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254326.1
CDS	185..1939
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKNQVRRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGRQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	XM_006254264.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254264.3

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGCAGTC CTTGATGGAA 
ATGCAGTGCC GGCATGGGGC GAGAACCAGC GACTCTGACC AGCAGGCTTA CCTGTTTCAA 
AGAGGAGCCG AGGACATGAG CTGGCAGCAT GGGCAGCAGC CCCGGAGTAT TCCCATTCAC 
TCGTGCCCCA AGTGTGGGGA GGTCCTGCCG GACATTGACA CGCTTCAGAT ACATGTGATG 
GACTGTATCA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Optn ( XM_006254262.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254324.1 Rattus norvegicus optineurin (Optn), transcript variant X3, mRNA.

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CloneID	ORa38061
Clone ID Related Accession (Same CDS sequence)	XM_006254262.3
Accession Version	XM_006254262.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1938bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	optineurin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254262.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTATGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CACTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGTAGGCA GTCCTTGATG 
GAAATGCAGT GCCGGCATGG GGCGAGAACC AGCGACTCTG ACCAGCAGGC TTACCTGTTT 
CAAAGAGGAG CCGAGGACAT GAGCTGGCAG CATGGGCAGC AGCCCCGGAG TATTCCCATT 
CACTCGTGCC CCAAGTGTGG GGAGGTCCTG CCGGACATTG ACACGCTTCA GATACATGTG 
ATGGACTGTA TCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254324.1
CDS	186..2123
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKNQVRRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGRCGRLPQSVYGDHRTGVSSLPQSVYGDHRTGVSSLPHSVYGDHRTGVSSLPHSVYGDHRTGRQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	XM_006254262.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254262.3

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTATGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CACTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGTAGGCA GTCCTTGATG 
GAAATGCAGT GCCGGCATGG GGCGAGAACC AGCGACTCTG ACCAGCAGGC TTACCTGTTT 
CAAAGAGGAG CCGAGGACAT GAGCTGGCAG CATGGGCAGC AGCCCCGGAG TATTCCCATT 
CACTCGTGCC CCAAGTGTGG GGAGGTCCTG CCGGACATTG ACACGCTTCA GATACATGTG 
ATGGACTGTA TCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Optn ( XM_017600454.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455943.1 Rattus norvegicus optineurin (Optn), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58994
Clone ID Related Accession (Same CDS sequence)	XM_017600454.1
Accession Version	XM_017600454.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	optineurin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTACGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CAGTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGAGTCAG TTCCCTGCCA 
CACTCTGTGT ATGGAGATCA CAGGACAGGT AGGCAGTCCT TGATGGAAAT GCAGTGCCGG 
CATGGGGCGA GAACCAGCGA CTCTGACCAG CAGGCTTACC TGTTTCAAAG AGGAGCCGAG 
GACATGAGCT GGCAGCATGG GCAGCAGCCC CGGAGTATTC CCATTCACTC GTGCCCCAAG 
TGTGGGGAGG TCCTGCCGGA CATTGACACG CTTCAGATAC ATGTGATGGA CTGTATCATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455943.1
CDS	186..2168
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKNQVRRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGRCGRLPQSVYGDHRTGVSSLPQSVYGDHRTGVSSLPQSVYGDHRTGVSSLPHSVYGDHRTGVSSLPHSVYGDHRTGRQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	XM_017600454.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600454.1

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTACGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CAGTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGAGTCAG TTCCCTGCCA 
CACTCTGTGT ATGGAGATCA CAGGACAGGT AGGCAGTCCT TGATGGAAAT GCAGTGCCGG 
CATGGGGCGA GAACCAGCGA CTCTGACCAG CAGGCTTACC TGTTTCAAAG AGGAGCCGAG 
GACATGAGCT GGCAGCATGG GCAGCAGCCC CGGAGTATTC CCATTCACTC GTGCCCCAAG 
TGTGGGGAGG TCCTGCCGGA CATTGACACG CTTCAGATAC ATGTGATGGA CTGTATCATC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Optn ( XM_017600455.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455944.1 Rattus norvegicus optineurin (Optn), transcript variant X2, mRNA.

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CloneID	ORa58995
Clone ID Related Accession (Same CDS sequence)	XM_017600455.1
Accession Version	XM_017600455.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1980bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	optineurin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTACGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CAGTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGAGTCAG TTCCCTGCCA 
CACTCTGTGT ATGGAGATCA CAGGACAGGG CAGTCCTTGA TGGAAATGCA GTGCCGGCAT 
GGGGCGAGAA CCAGCGACTC TGACCAGCAG GCTTACCTGT TTCAAAGAGG AGCCGAGGAC 
ATGAGCTGGC AGCATGGGCA GCAGCCCCGG AGTATTCCCA TTCACTCGTG CCCCAAGTGT 
GGGGAGGTCC TGCCGGACAT TGACACGCTT CAGATACATG TGATGGACTG TATCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455944.1
CDS	186..2165
Translation	MSHQPLSCLTEKGDSSCETPGNGPSNMVHPNLDTFTPEELLQQMKELLVENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQLFEIQSKEAKERLKALSHENERLKEELGKLKEKSERPFEDITGRCGFPRTDLEQEVEQLKRQVEQEVEHLKNQVRRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMTEGEAEGAMKEMRNSAGPTRTDSISMGKCTEDARTCVEFEELTVSQLLLCLREGNQKVERLEIALREAKERISDFEKKANGHSAIETQTEGSTQKEEEDKDPESVGIEVETLNVQVASLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELVYSNRKLELQVESMRSEIKMEQAKTEEEKSRLATLQATHDKLLQEHNKALRTIEELTKQQAEKVDKVQLQELSEKLELAEQALASKQLQMDEMKQTIAKQEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNDFEDGGRCGRLPQSVYGDHRTGVSSLPQSVYGDHRTGVSSLPQSVYGDHRTGVSSLPHSVYGDHRTGVSSLPHSVYGDHRTGQSLMEMQCRHGARTSDSDQQAYLFQRGAEDMSWQHGQQPRSIPIHSCPKCGEVLPDIDTLQIHVMDCII

Target ORF information:

RefSeq Version	XM_017600455.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus optineurin (Optn), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600455.1

ORF Insert Sequence:

ATGTCCCATC AACCTCTGAG CTGCCTGACT GAGAAGGGGG ACAGCTCCTG TGAGACCCCA 
GGAAATGGAC CCTCCAATAT GGTTCACCCC AACCTGGACA CATTCACTCC TGAGGAGCTG 
CTGCAGCAAA TGAAAGAACT CCTGGTCGAG AACCACCAGC TGAAAGAAGC CATGAAGCTA 
AATAATCAAG CTATGAAAGG GCGATTTGAG GAGCTTTCTG CCTGGACAGA GAAGCAGAAG 
GAAGAACGCC AGTTGTTTGA GATACAAAGC AAAGAGGCTA AGGAGCGCCT CAAGGCCCTG 
AGTCATGAAA ATGAGAGGCT GAAGGAAGAG CTTGGAAAAC TAAAAGAGAA ATCAGAAAGG 
CCATTTGAAG ACATCACAGG TAGATGCGGG TTTCCCAGAA CCGACTTGGA GCAGGAAGTG 
GAGCAACTGA AGAGGCAGGT GGAGCAGGAA GTGGAGCATC TGAAGAACCA GGTGAGGCGC 
CTTCAGGCTG AGAAAGCGGA CCTGCTGGGC ATCGTCTCAG AACTGCAGCT CAAGCTCAAC 
TCCAGCGGCT CCTCAGAAGA CTCCTTCGTG GAGATCAGGA TGACTGAAGG AGAGGCGGAA 
GGGGCAATGA AGGAGATGAG GAACAGCGCT GGACCCACAA GGACAGACTC CATCAGCATG 
GGCAAATGTA CAGAGGACGC CAGGACTTGT GTGGAGTTTG AGGAACTGAC TGTGAGCCAA 
CTCCTGCTTT GCCTCAGGGA AGGAAACCAA AAGGTGGAGA GACTCGAGAT CGCGCTCAGA 
GAAGCCAAAG AAAGAATTTC AGATTTTGAA AAGAAAGCAA ACGGCCATTC TGCGATTGAG 
ACCCAGACAG AGGGGAGCAC ACAAAAAGAA GAGGAGGACA AAGACCCAGA GAGTGTGGGA 
ATCGAAGTGG AAACTCTGAA TGTTCAAGTG GCCTCTCTGT TTAAGGAGCT TCAAGAGGCG 
CACACAAAGC TCAGTGAGGC CGAGCTGATG AAGAAGAGAC TTCAAGAAAA GTGTCAGGCT 
CTGGAAAGGA AGAACTCTGC AACCCCATCG GAGCTGAATG AAAAGCAAGA GCTCGTTTAC 
AGTAACAGGA AGTTAGAGCT GCAGGTGGAG AGCATGCGCT CGGAAATCAA GATGGAGCAG 
GCCAAGACAG AGGAGGAGAA ATCCAGGTTA GCCACTCTTC AGGCAACACA CGACAAGCTT 
CTTCAGGAAC ACAATAAAGC TCTGAGAACA ATTGAAGAAC TAACCAAACA ACAGGCAGAA 
AAAGTGGACA AGGTGCAGCT GCAGGAGCTC AGCGAGAAGC TGGAGCTGGC GGAGCAGGCT 
CTGGCGTCCA AGCAGCTCCA GATGGATGAG ATGAAGCAGA CCATCGCCAA GCAGGAGGAG 
GACCTGGAGA CCATGGCCGT CCTCAGGGCT CAGATGGAGG TGTACTGTTC AGATTTCCAT 
GCTGAGAGGG CAGCAAGGGA GAAGATCCAT GAGGAAAAGG AGCAGCTGGC CTTGCAGCTC 
GCCATTTTGC TGAAAGAGAA CAATGACTTT GAAGATGGAG GCAGGTGTGG ACGCTTGCCA 
CAATCTGTGT ACGGAGATCA CAGGACAGGA GTCAGTTCCC TGCCACAGTC TGTGTACGGA 
GATCACAGGA CAGGAGTCAG TTCCCTGCCA CAGTCTGTGT ATGGAGATCA CAGGACAGGA 
GTCAGTTCCC TGCCACACTC TGTGTATGGA GATCACAGGA CAGGAGTCAG TTCCCTGCCA 
CACTCTGTGT ATGGAGATCA CAGGACAGGG CAGTCCTTGA TGGAAATGCA GTGCCGGCAT 
GGGGCGAGAA CCAGCGACTC TGACCAGCAG GCTTACCTGT TTCAAAGAGG AGCCGAGGAC 
ATGAGCTGGC AGCATGGGCA GCAGCCCCGG AGTATTCCCA TTCACTCGTG CCCCAAGTGT 
GGGGAGGTCC TGCCGGACAT TGACACGCTT CAGATACATG TGATGGACTG TATCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of optineurin isolated from rat-injured dental pulp and the effects on inflammatory signals in normal rat kidney cells.
Odontology(2017 Aug)
Senoo K,Yamashiro K,Yamamoto T,Myokai F,Kawamura M,Takashiba S

A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.
Amyotrophic lateral sclerosis & frontotemporal degeneration18(1-2)126-133(2017 Feb)
Fifita JA,Williams KL,Sundaramoorthy V,Mccann EP,Nicholson GA,Atkin JD,Blair IP

Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity.
Molecular vision23447-456(2017)
Hu X,Dai Y,Sun X

From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models.
Toxicological sciences : an official journal of the Society of Toxicology153(2)372-81(2016 Oct)
Wise JP Jr,Cannon J

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Optn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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