Prpf19 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prpf19
Entrez Gene ID	246216
Full Name	pre-mRNA processing factor 19
Synonyms	Prp19
General protein information	Preferred Names pre-mRNA processing factor 19 Names pre-mRNA-processing factor 19 PRP19/PSO4 homolog PRP19/PSO4 pre-mRNA processing factor 19 homolog RING-type E3 ubiquitin transferase PRP19 neuronal differentiation-related gene protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43
Summary	human homolog is involved in DNA double strand break repair [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006231014.3	XP_006231076.1	pre-mRNA-processing factor 19 isoform X2
XM_006231015.3	XP_006231077.1	pre-mRNA-processing factor 19 isoform X3
XM_006231013.3	XP_006231075.1	pre-mRNA-processing factor 19 isoform X1
NM_139333.3	NP_647549.2	pre-mRNA-processing factor 19

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PRPF19	NP_001034420.1
	PRPF19	XP_001084826.2
Bos taurus (cattle)	PRPF19	NP_001069108.1
Xenopus tropicalis (tropical clawed frog)	prpf19	NP_001005435.1
Homo sapiens (human)	PRPF19	NP_055317.1
Drosophila melanogaster (fruit fly)	Prp19	NP_523783.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007217	XP_308568.4
Rattus norvegicus (Norway rat)	Prpf19	NP_647549.2
Danio rerio (zebrafish)	prp19	NP_958875.1
Arabidopsis thaliana (thale cress)	MAC3B	NP_850207.4
Pan troglodytes (chimpanzee)	PRPF19	XP_001142421.1
Canis lupus familiaris (dog)	PRPF19	XP_853782.1
Mus musculus (house mouse)	Prpf19	NP_598890.1
Arabidopsis thaliana (thale cress)	MAC3A	NP_563708.1
Oryza sativa (rice)	Os10g0466300	NP_001064804.1

Gene Ontology
Bibliography

Related articles in PubMed

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, L?hrmann R
Nature542(7641)318-323(2017 02)

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
Mar?chal A, Li JM, Ji XY, Wu CS, Yazinski SA, Nguyen HD, Liu S, Jim?nez AE, Jin J, Zou L
Molecular cell53(2)235-246(2014 Jan)

Splicing and beyond: the many faces of the Prp19 complex.
Chanarat S, Str??er K
Biochimica et biophysica acta1833(10)2126-34(2013 Oct)

The U-box-type ubiquitin ligase PRP19? regulates astrocyte differentiation via ubiquitination of PTP1B.
Yamada T, Urano-Tashiro Y, Hashi Y, Sakumoto M, Akiyama H, Tashiro F
Brain research152412-25(2013 Aug)

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M
Genes & development24(13)1434-47(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results indicate that PRP19beta activates the gp130/Janus kinase (JAK)/STAT signaling pathway during astrocyte differentiation via PTP1B ubiquitination
Title: The U-box-type ubiquitin ligase PRP19? regulates astrocyte differentiation via ubiquitination of PTP1B.

The following Prpf19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prpf19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12492	NM_139333.3 Latest version!	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$293.30 $419.00
ORa23884	XM_006231013.3 Latest version!	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa23885	XM_006231014.3 Latest version!	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa23886	XM_006231015.3 Latest version!	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prpf19 ( NM_139333.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_647549.2 Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), mRNA.

Price & Availability↑

CloneID	ORa12492
Clone ID Related Accession (Same CDS sequence)	NM_139333.3
Accession Version	NM_139333.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	pre-mRNA-processing factor 19
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC107669.1. On Oct 31, 2005 this sequence version replaced NM_139333.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC107669.1, AB020022.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGATG CAGTCATGCT GCACAGCTTC ACTCTTCGCC AGCAGCTGCA GACAACCCGC 
CAGGAACTGT CCCACGCTCT GTACCAGCAC GATGCTGCCT GCCGAGTCAT TGCCCGGCTC 
ACCAAGGAGG TCACTGCTGC TCGAGAAGCT CTGGCTACTC TGAAACCACA GGCTGGTCTT 
ATTGTACCTC AGGCTGTGCC AAGCTCACAG CCCAGTGTTG TGGGTGCAGG AGAGCCCATG 
GATTTGGGTG AGCTTGTGGG AATGACCCCT GAGATTATCC AGAAGCTTCA AGACAAGGCC 
ACTGTACTAA CCACGGAGCG TAAGAAGAGA GGAAAAACTG TCCCTGAGGA GCTGGTGAAG 
CCTGAAGAGC TCAGCAAGTA CCGGCAGGTG GCATCCCATG TGGGGCTACA CAGTGCTAGC 
ATTCCTGGGA TTCTTGCTCT GGACCTGTGT CCCTCAGACA CCAACAAGAT TCTTACTGGT 
GGGGCAGATA AAAACGTTGT TGTCTTTGAT AAGAGTACTG AGCAAATCCT GGCCACTCTC 
AAAGGCCATA CCAAGAAGGT CACCAGTGTG GTGTTTCATC CTTCTCAGGA ATTGGTGTTT 
TCTGCGTCCC CTGATGCTAC TATCAGGATT TGGTCCGTCC CGAACACTTC TTGTGTACAG 
GTTGTTCGGG CCCATGAGAG TGCGGTGACA GGACTCAGCC TCCATGCCAC TGGAGACTAT 
CTACTGAGCT CCTCTGATGA TCAGTACTGG GCGTTCTCTG ACATTCAGAC AGGGCGTGTG 
CTCACCAAGG TGACAGATGA GACTTCCGGC TGCTCTCTTA CCTGTGCACA GTTCCACCCT 
GATGGCCTCA TCTTTGGAAC AGGAACCATG GACTCCCAGA TCAAGATCTG GGACTTGAAG 
GAACGCACCA ATGTGGCGAA CTTCCCTGGC CACTCCGGCC CCATTACCAG CATTGCCTTC 
TCTGAGAATG GGTACTACCT GGCCACGGCA GCTGATGACT CCTCAGTCAA GCTCTGGGAC 
TTACGCAAGT TGAAGAACTT CAAGACATTG CAGCTGGACA ACAACTTTGA GGTGAAGTCA 
CTAATCTTTG ACCAGAGTGG CACCTACCTG GCGCTTGGGG GTACAGATGT CCAGATCTAC 
ATCTGCAAAC AGTGGACAGA GATTCTTCAC TTTACAGAGC ATAGTGGCCT GACCACTGGA 
GTGGCCTTTG GGCACCACGC CAAGTTCATC GCTTCAACCG GCATGGACAG GAGCCTCAAA 
TTCTACAGTC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_647549.2
CDS	188..1702
Translation	MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL

Target ORF information:

RefSeq Version	NM_139333.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139333.3

ORF Insert Sequence:

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGATG CAGTCATGCT GCACAGCTTC ACTCTTCGCC AGCAGCTGCA GACAACCCGC 
CAGGAACTGT CCCACGCTCT GTACCAGCAC GATGCTGCCT GCCGAGTCAT TGCCCGGCTC 
ACCAAGGAGG TCACTGCTGC TCGAGAAGCT CTGGCTACTC TGAAACCACA GGCTGGTCTT 
ATTGTACCTC AGGCTGTGCC AAGCTCACAG CCCAGTGTTG TGGGTGCAGG AGAGCCCATG 
GATTTGGGTG AGCTTGTGGG AATGACCCCT GAGATTATCC AGAAGCTTCA AGACAAGGCC 
ACTGTACTAA CCACGGAGCG TAAGAAGAGA GGAAAAACTG TCCCTGAGGA GCTGGTGAAG 
CCTGAAGAGC TCAGCAAGTA CCGGCAGGTG GCATCCCATG TGGGGCTACA CAGTGCTAGC 
ATTCCTGGGA TTCTTGCTCT GGACCTGTGT CCCTCAGACA CCAACAAGAT TCTTACTGGT 
GGGGCAGATA AAAACGTTGT TGTCTTTGAT AAGAGTACTG AGCAAATCCT GGCCACTCTC 
AAAGGCCATA CCAAGAAGGT CACCAGTGTG GTGTTTCATC CTTCTCAGGA ATTGGTGTTT 
TCTGCGTCCC CTGATGCTAC TATCAGGATT TGGTCCGTCC CGAACACTTC TTGTGTACAG 
GTTGTTCGGG CCCATGAGAG TGCGGTGACA GGACTCAGCC TCCATGCCAC TGGAGACTAT 
CTACTGAGCT CCTCTGATGA TCAGTACTGG GCGTTCTCTG ACATTCAGAC AGGGCGTGTG 
CTCACCAAGG TGACAGATGA GACTTCCGGC TGCTCTCTTA CCTGTGCACA GTTCCACCCT 
GATGGCCTCA TCTTTGGAAC AGGAACCATG GACTCCCAGA TCAAGATCTG GGACTTGAAG 
GAACGCACCA ATGTGGCGAA CTTCCCTGGC CACTCCGGCC CCATTACCAG CATTGCCTTC 
TCTGAGAATG GGTACTACCT GGCCACGGCA GCTGATGACT CCTCAGTCAA GCTCTGGGAC 
TTACGCAAGT TGAAGAACTT CAAGACATTG CAGCTGGACA ACAACTTTGA GGTGAAGTCA 
CTAATCTTTG ACCAGAGTGG CACCTACCTG GCGCTTGGGG GTACAGATGT CCAGATCTAC 
ATCTGCAAAC AGTGGACAGA GATTCTTCAC TTTACAGAGC ATAGTGGCCT GACCACTGGA 
GTGGCCTTTG GGCACCACGC CAAGTTCATC GCTTCAACCG GCATGGACAG GAGCCTCAAA 
TTCTACAGTC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prpf19 ( XM_006231013.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231075.1 Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23884
Clone ID Related Accession (Same CDS sequence)	XM_006231013.3
Accession Version	XM_006231013.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pre-mRNA-processing factor 19 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231013.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGGTT GGCCGAATTC TCCGGCTCTC CCCCAGTCCT CACAGTGGCC TACCCTCTCC 
CAGGATGCAG TCATGCTGCA CAGCTTCACT CTTCGCCAGC AGCTGCAGAC AACCCGCCAG 
GAACTGTCCC ACGCTCTGTA CCAGCACGAT GCTGCCTGCC GAGTCATTGC CCGGCTCACC 
AAGGAGGTCA CTGCTGCTCG AGAAGCTCTG GCTACTCTGA AACCACAGGC TGGTCTTATT 
GTACCTCAGG CTGTGCCAAG CTCACAGCCC AGTGTTGTGG GTGCAGGAGA GCCCATGGAT 
TTGGGTGAGC TTGTGGGAAT GACCCCTGAG ATTATCCAGA AGCTTCAAGA CAAGGCCACT 
GTACTAACCA CGGAGCGTAA GAAGAGAGGA AAAACTGTCC CTGAGGAGCT GGTGAAGCCT 
GAAGAGCTCA GCAAGTACCG GCAGGTGGCA TCCCATGTGG GGCTACACAG TGCTAGCATT 
CCTGGGATTC TTGCTCTGGA CCTGTGTCCC TCAGACACCA ACAAGATTCT TACTGGTGGG 
GCAGATAAAA ACGTTGTTGT CTTTGATAAG AGTACTGAGC AAATCCTGGC CACTCTCAAA 
GGCCATACCA AGAAGGTCAC CAGTGTGGTG TTTCATCCTT CTCAGGAATT GGTGTTTTCT 
GCGTCCCCTG ATGCTACTAT CAGGATTTGG TCCGTCCCGA ACACTTCTTG TGTACAGGTT 
GTTCGGGCCC ATGAGAGTGC GGTGACAGGA CTCAGCCTCC ATGCCACTGG AGACTATCTA 
CTGAGCTCCT CTGATGATCA GTACTGGGCG TTCTCTGACA TTCAGACAGG GCGTGTGCTC 
ACCAAGGTGA CAGATGAGAC TTCCGGCTGC TCTCTTACCT GTGCACAGTT CCACCCTGAT 
GGCCTCATCT TTGGAACAGG AACCATGGAC TCCCAGATCA AGATCTGGGA CTTGAAGGAA 
CGCACCAATG TGGCGAACTT CCCTGGCCAC TCCGGCCCCA TTACCAGCAT TGCCTTCTCT 
GAGAATGGGT ACTACCTGGC CACGGCAGCT GATGACTCCT CAGTCAAGCT CTGGGACTTA 
CGCAAGTTGA AGAACTTCAA GACATTGCAG CTGGACAACA ACTTTGAGGT GAAGTCACTA 
ATCTTTGACC AGAGTGGCAC CTACCTGGCG CTTGGGGGTA CAGATGTCCA GATCTACATC 
TGCAAACAGT GGACAGAGAT TCTTCACTTT ACAGAGCATT GTGGCCCAGG AAAAGTACTT 
GTGAGTCTGT CCCAGAGTAC TGCTACTAGC TGGCCTCTCC CAAGCTGTGT GTTGAGGAGC 
AAACTGATCT CCCTGGTGTT CCAGGAAAAT TGGAATACAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231075.1
CDS	228..1829
Translation	MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWGWPNSPALPQSSQWPTLSQDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHCGPGKVLVSLSQSTATSWPLPSCVLRSKLISLVFQENWNT

Target ORF information:

RefSeq Version	XM_006231013.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231013.3

ORF Insert Sequence:

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGGTT GGCCGAATTC TCCGGCTCTC CCCCAGTCCT CACAGTGGCC TACCCTCTCC 
CAGGATGCAG TCATGCTGCA CAGCTTCACT CTTCGCCAGC AGCTGCAGAC AACCCGCCAG 
GAACTGTCCC ACGCTCTGTA CCAGCACGAT GCTGCCTGCC GAGTCATTGC CCGGCTCACC 
AAGGAGGTCA CTGCTGCTCG AGAAGCTCTG GCTACTCTGA AACCACAGGC TGGTCTTATT 
GTACCTCAGG CTGTGCCAAG CTCACAGCCC AGTGTTGTGG GTGCAGGAGA GCCCATGGAT 
TTGGGTGAGC TTGTGGGAAT GACCCCTGAG ATTATCCAGA AGCTTCAAGA CAAGGCCACT 
GTACTAACCA CGGAGCGTAA GAAGAGAGGA AAAACTGTCC CTGAGGAGCT GGTGAAGCCT 
GAAGAGCTCA GCAAGTACCG GCAGGTGGCA TCCCATGTGG GGCTACACAG TGCTAGCATT 
CCTGGGATTC TTGCTCTGGA CCTGTGTCCC TCAGACACCA ACAAGATTCT TACTGGTGGG 
GCAGATAAAA ACGTTGTTGT CTTTGATAAG AGTACTGAGC AAATCCTGGC CACTCTCAAA 
GGCCATACCA AGAAGGTCAC CAGTGTGGTG TTTCATCCTT CTCAGGAATT GGTGTTTTCT 
GCGTCCCCTG ATGCTACTAT CAGGATTTGG TCCGTCCCGA ACACTTCTTG TGTACAGGTT 
GTTCGGGCCC ATGAGAGTGC GGTGACAGGA CTCAGCCTCC ATGCCACTGG AGACTATCTA 
CTGAGCTCCT CTGATGATCA GTACTGGGCG TTCTCTGACA TTCAGACAGG GCGTGTGCTC 
ACCAAGGTGA CAGATGAGAC TTCCGGCTGC TCTCTTACCT GTGCACAGTT CCACCCTGAT 
GGCCTCATCT TTGGAACAGG AACCATGGAC TCCCAGATCA AGATCTGGGA CTTGAAGGAA 
CGCACCAATG TGGCGAACTT CCCTGGCCAC TCCGGCCCCA TTACCAGCAT TGCCTTCTCT 
GAGAATGGGT ACTACCTGGC CACGGCAGCT GATGACTCCT CAGTCAAGCT CTGGGACTTA 
CGCAAGTTGA AGAACTTCAA GACATTGCAG CTGGACAACA ACTTTGAGGT GAAGTCACTA 
ATCTTTGACC AGAGTGGCAC CTACCTGGCG CTTGGGGGTA CAGATGTCCA GATCTACATC 
TGCAAACAGT GGACAGAGAT TCTTCACTTT ACAGAGCATT GTGGCCCAGG AAAAGTACTT 
GTGAGTCTGT CCCAGAGTAC TGCTACTAGC TGGCCTCTCC CAAGCTGTGT GTTGAGGAGC 
AAACTGATCT CCCTGGTGTT CCAGGAAAAT TGGAATACAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prpf19 ( XM_006231014.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231076.1 Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa23885
Clone ID Related Accession (Same CDS sequence)	XM_006231014.3
Accession Version	XM_006231014.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pre-mRNA-processing factor 19 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231014.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGGTT GGCCGAATTC TCCGGCTCTC CCCCAGTCCT CACAGTGGCC TACCCTCTCC 
CAGGATGCAG TCATGCTGCA CAGCTTCACT CTTCGCCAGC AGCTGCAGAC AACCCGCCAG 
GAACTGTCCC ACGCTCTGTA CCAGCACGAT GCTGCCTGCC GAGTCATTGC CCGGCTCACC 
AAGGAGGTCA CTGCTGCTCG AGAAGCTCTG GCTACTCTGA AACCACAGGC TGGTCTTATT 
GTACCTCAGG CTGTGCCAAG CTCACAGCCC AGTGTTGTGG GTGCAGGAGA GCCCATGGAT 
TTGGGTGAGC TTGTGGGAAT GACCCCTGAG ATTATCCAGA AGCTTCAAGA CAAGGCCACT 
GTACTAACCA CGGAGCGTAA GAAGAGAGGA AAAACTGTCC CTGAGGAGCT GGTGAAGCCT 
GAAGAGCTCA GCAAGTACCG GCAGGTGGCA TCCCATGTGG GGCTACACAG TGCTAGCATT 
CCTGGGATTC TTGCTCTGGA CCTGTGTCCC TCAGACACCA ACAAGATTCT TACTGGTGGG 
GCAGATAAAA ACGTTGTTGT CTTTGATAAG AGTACTGAGC AAATCCTGGC CACTCTCAAA 
GGCCATACCA AGAAGGTCAC CAGTGTGGTG TTTCATCCTT CTCAGGAATT GGTGTTTTCT 
GCGTCCCCTG ATGCTACTAT CAGGATTTGG TCCGTCCCGA ACACTTCTTG TGTACAGGTT 
GTTCGGGCCC ATGAGAGTGC GGTGACAGGA CTCAGCCTCC ATGCCACTGG AGACTATCTA 
CTGAGCTCCT CTGATGATCA GTACTGGGCG TTCTCTGACA TTCAGACAGG GCGTGTGCTC 
ACCAAGGTGA CAGATGAGAC TTCCGGCTGC TCTCTTACCT GTGCACAGTT CCACCCTGAT 
GGCCTCATCT TTGGAACAGG AACCATGGAC TCCCAGATCA AGATCTGGGA CTTGAAGGAA 
CGCACCAATG TGGCGAACTT CCCTGGCCAC TCCGGCCCCA TTACCAGCAT TGCCTTCTCT 
GAGAATGGGT ACTACCTGGC CACGGCAGCT GATGACTCCT CAGTCAAGCT CTGGGACTTA 
CGCAAGTTGA AGAACTTCAA GACATTGCAG CTGGACAACA ACTTTGAGGT GAAGTCACTA 
ATCTTTGACC AGAGTGGCAC CTACCTGGCG CTTGGGGGTA CAGATGTCCA GATCTACATC 
TGCAAACAGT GGACAGAGAT TCTTCACTTT ACAGAGCATA GTGGCCTGAC CACTGGAGTG 
GCCTTTGGGC ACCACGCCAA GTTCATCGCT TCAACCGGCA TGGACAGGAG CCTCAAATTC 
TACAGTCTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231076.1
CDS	226..1797
Translation	MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWGWPNSPALPQSSQWPTLSQDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL

Target ORF information:

RefSeq Version	XM_006231014.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231014.3

ORF Insert Sequence:

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGGTT GGCCGAATTC TCCGGCTCTC CCCCAGTCCT CACAGTGGCC TACCCTCTCC 
CAGGATGCAG TCATGCTGCA CAGCTTCACT CTTCGCCAGC AGCTGCAGAC AACCCGCCAG 
GAACTGTCCC ACGCTCTGTA CCAGCACGAT GCTGCCTGCC GAGTCATTGC CCGGCTCACC 
AAGGAGGTCA CTGCTGCTCG AGAAGCTCTG GCTACTCTGA AACCACAGGC TGGTCTTATT 
GTACCTCAGG CTGTGCCAAG CTCACAGCCC AGTGTTGTGG GTGCAGGAGA GCCCATGGAT 
TTGGGTGAGC TTGTGGGAAT GACCCCTGAG ATTATCCAGA AGCTTCAAGA CAAGGCCACT 
GTACTAACCA CGGAGCGTAA GAAGAGAGGA AAAACTGTCC CTGAGGAGCT GGTGAAGCCT 
GAAGAGCTCA GCAAGTACCG GCAGGTGGCA TCCCATGTGG GGCTACACAG TGCTAGCATT 
CCTGGGATTC TTGCTCTGGA CCTGTGTCCC TCAGACACCA ACAAGATTCT TACTGGTGGG 
GCAGATAAAA ACGTTGTTGT CTTTGATAAG AGTACTGAGC AAATCCTGGC CACTCTCAAA 
GGCCATACCA AGAAGGTCAC CAGTGTGGTG TTTCATCCTT CTCAGGAATT GGTGTTTTCT 
GCGTCCCCTG ATGCTACTAT CAGGATTTGG TCCGTCCCGA ACACTTCTTG TGTACAGGTT 
GTTCGGGCCC ATGAGAGTGC GGTGACAGGA CTCAGCCTCC ATGCCACTGG AGACTATCTA 
CTGAGCTCCT CTGATGATCA GTACTGGGCG TTCTCTGACA TTCAGACAGG GCGTGTGCTC 
ACCAAGGTGA CAGATGAGAC TTCCGGCTGC TCTCTTACCT GTGCACAGTT CCACCCTGAT 
GGCCTCATCT TTGGAACAGG AACCATGGAC TCCCAGATCA AGATCTGGGA CTTGAAGGAA 
CGCACCAATG TGGCGAACTT CCCTGGCCAC TCCGGCCCCA TTACCAGCAT TGCCTTCTCT 
GAGAATGGGT ACTACCTGGC CACGGCAGCT GATGACTCCT CAGTCAAGCT CTGGGACTTA 
CGCAAGTTGA AGAACTTCAA GACATTGCAG CTGGACAACA ACTTTGAGGT GAAGTCACTA 
ATCTTTGACC AGAGTGGCAC CTACCTGGCG CTTGGGGGTA CAGATGTCCA GATCTACATC 
TGCAAACAGT GGACAGAGAT TCTTCACTTT ACAGAGCATA GTGGCCTGAC CACTGGAGTG 
GCCTTTGGGC ACCACGCCAA GTTCATCGCT TCAACCGGCA TGGACAGGAG CCTCAAATTC 
TACAGTCTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prpf19 ( XM_006231015.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231077.1 Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X3, mRNA.

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CloneID	ORa23886
Clone ID Related Accession (Same CDS sequence)	XM_006231015.3
Accession Version	XM_006231015.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pre-mRNA-processing factor 19 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231015.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGATG CAGTCATGCT GCACAGCTTC ACTCTTCGCC AGCAGCTGCA GACAACCCGC 
CAGGAACTGT CCCACGCTCT GTACCAGCAC GATGCTGCCT GCCGAGTCAT TGCCCGGCTC 
ACCAAGGAGG TCACTGCTGC TCGAGAAGCT CTGGCTACTC TGAAACCACA GGCTGGTCTT 
ATTGTACCTC AGGCTGTGCC AAGCTCACAG CCCAGTGTTG TGGGTGCAGG AGAGCCCATG 
GATTTGGGTG AGCTTGTGGG AATGACCCCT GAGATTATCC AGAAGCTTCA AGACAAGGCC 
ACTGTACTAA CCACGGAGCG TAAGAAGAGA GGAAAAACTG TCCCTGAGGA GCTGGTGAAG 
CCTGAAGAGC TCAGCAAGTA CCGGCAGGTG GCATCCCATG TGGGGCTACA CAGTGCTAGC 
ATTCCTGGGA TTCTTGCTCT GGACCTGTGT CCCTCAGACA CCAACAAGAT TCTTACTGGT 
GGGGCAGATA AAAACGTTGT TGTCTTTGAT AAGAGTACTG AGCAAATCCT GGCCACTCTC 
AAAGGCCATA CCAAGAAGGT CACCAGTGTG GTGTTTCATC CTTCTCAGGA ATTGGTGTTT 
TCTGCGTCCC CTGATGCTAC TATCAGGATT TGGTCCGTCC CGAACACTTC TTGTGTACAG 
GTTGTTCGGG CCCATGAGAG TGCGGTGACA GGACTCAGCC TCCATGCCAC TGGAGACTAT 
CTACTGAGCT CCTCTGATGA TCAGTACTGG GCGTTCTCTG ACATTCAGAC AGGGCGTGTG 
CTCACCAAGG TGACAGATGA GACTTCCGGC TGCTCTCTTA CCTGTGCACA GTTCCACCCT 
GATGGCCTCA TCTTTGGAAC AGGAACCATG GACTCCCAGA TCAAGATCTG GGACTTGAAG 
GAACGCACCA ATGTGGCGAA CTTCCCTGGC CACTCCGGCC CCATTACCAG CATTGCCTTC 
TCTGAGAATG GGTACTACCT GGCCACGGCA GCTGATGACT CCTCAGTCAA GCTCTGGGAC 
TTACGCAAGT TGAAGAACTT CAAGACATTG CAGCTGGACA ACAACTTTGA GGTGAAGTCA 
CTAATCTTTG ACCAGAGTGG CACCTACCTG GCGCTTGGGG GTACAGATGT CCAGATCTAC 
ATCTGCAAAC AGTGGACAGA GATTCTTCAC TTTACAGAGC ATTGTGGCCC AGGAAAAGTA 
CTTGTGAGTC TGTCCCAGAG TACTGCTACT AGCTGGCCTC TCCCAAGCTG TGTGTTGAGG 
AGCAAACTGA TCTCCCTGGT GTTCCAGGAA AATTGGAATA CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231077.1
CDS	227..1771
Translation	MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHCGPGKVLVSLSQSTATSWPLPSCVLRSKLISLVFQENWNT

Target ORF information:

RefSeq Version	XM_006231015.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pre-mRNA processing factor 19 (Prpf19), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231015.3

ORF Insert Sequence:

ATGTCCCTGA TCTGCTCGAT CTCCAACGAA GTGCCAGAGC ACCCATGCGT GTCCCCTGTC 
TCTAATCATG TGTATGAGCG GCGACTCATT GAGAAGTACA TTGCAGAGAA TGGCACAGAT 
CCTATCAACA ACCAGCCTCT CTCAGAGGAG CAGCTCATCG ACATCAAAGT TGCTCATCCA 
ATCCGGCCCA AGCCTCCCTC TGCCACCAGC ATCCCAGCCA TTCTGAAAGC CTTGCAGGAT 
GAGTGGGATG CAGTCATGCT GCACAGCTTC ACTCTTCGCC AGCAGCTGCA GACAACCCGC 
CAGGAACTGT CCCACGCTCT GTACCAGCAC GATGCTGCCT GCCGAGTCAT TGCCCGGCTC 
ACCAAGGAGG TCACTGCTGC TCGAGAAGCT CTGGCTACTC TGAAACCACA GGCTGGTCTT 
ATTGTACCTC AGGCTGTGCC AAGCTCACAG CCCAGTGTTG TGGGTGCAGG AGAGCCCATG 
GATTTGGGTG AGCTTGTGGG AATGACCCCT GAGATTATCC AGAAGCTTCA AGACAAGGCC 
ACTGTACTAA CCACGGAGCG TAAGAAGAGA GGAAAAACTG TCCCTGAGGA GCTGGTGAAG 
CCTGAAGAGC TCAGCAAGTA CCGGCAGGTG GCATCCCATG TGGGGCTACA CAGTGCTAGC 
ATTCCTGGGA TTCTTGCTCT GGACCTGTGT CCCTCAGACA CCAACAAGAT TCTTACTGGT 
GGGGCAGATA AAAACGTTGT TGTCTTTGAT AAGAGTACTG AGCAAATCCT GGCCACTCTC 
AAAGGCCATA CCAAGAAGGT CACCAGTGTG GTGTTTCATC CTTCTCAGGA ATTGGTGTTT 
TCTGCGTCCC CTGATGCTAC TATCAGGATT TGGTCCGTCC CGAACACTTC TTGTGTACAG 
GTTGTTCGGG CCCATGAGAG TGCGGTGACA GGACTCAGCC TCCATGCCAC TGGAGACTAT 
CTACTGAGCT CCTCTGATGA TCAGTACTGG GCGTTCTCTG ACATTCAGAC AGGGCGTGTG 
CTCACCAAGG TGACAGATGA GACTTCCGGC TGCTCTCTTA CCTGTGCACA GTTCCACCCT 
GATGGCCTCA TCTTTGGAAC AGGAACCATG GACTCCCAGA TCAAGATCTG GGACTTGAAG 
GAACGCACCA ATGTGGCGAA CTTCCCTGGC CACTCCGGCC CCATTACCAG CATTGCCTTC 
TCTGAGAATG GGTACTACCT GGCCACGGCA GCTGATGACT CCTCAGTCAA GCTCTGGGAC 
TTACGCAAGT TGAAGAACTT CAAGACATTG CAGCTGGACA ACAACTTTGA GGTGAAGTCA 
CTAATCTTTG ACCAGAGTGG CACCTACCTG GCGCTTGGGG GTACAGATGT CCAGATCTAC 
ATCTGCAAAC AGTGGACAGA GATTCTTCAC TTTACAGAGC ATTGTGGCCC AGGAAAAGTA 
CTTGTGAGTC TGTCCCAGAG TACTGCTACT AGCTGGCCTC TCCCAAGCTG TGTGTTGAGG 
AGCAAACTGA TCTCCCTGGT GTTCCAGGAA AATTGGAATA CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature542(7641)318-323(2017 02)
Bertram K,Agafonov DE,Liu WT,Dybkov O,Will CL,Hartmuth K,Urlaub H,Kastner B,Stark H,L?hrmann R

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
Molecular cell53(2)235-246(2014 Jan)
Mar?chal A,Li JM,Ji XY,Wu CS,Yazinski SA,Nguyen HD,Liu S,Jim?nez AE,Jin J,Zou L

Splicing and beyond: the many faces of the Prp19 complex.
Biochimica et biophysica acta1833(10)2126-34(2013 Oct)
Chanarat S,Str??er K

The U-box-type ubiquitin ligase PRP19? regulates astrocyte differentiation via ubiquitination of PTP1B.
Brain research152412-25(2013 Aug)
Yamada T,Urano-Tashiro Y,Hashi Y,Sakumoto M,Akiyama H,Tashiro F

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
Genes & development24(13)1434-47(2010 Jul)
Song EJ,Werner SL,Neubauer J,Stegmeier F,Aspden J,Rio D,Harper JW,Elledge SJ,Kirschner MW,Rape M

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Prpf19 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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