Nup58 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nup58
Entrez Gene ID	245922
Full Name	nucleoporin 58
Synonyms	Nup45,Nupl1,p58/p45
General protein information	Preferred Names nucleoporin 58 Names nucleoporin p58/p45 58 kDa nucleoporin nucleoporin p45 nucleoporin p58 nucleoporin-like 1 nucleoporin-like protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12
Summary	alternative splice products p58 and p45 are O-linked glycoprotein components of the nuclear pore p62 complex; may play a role in nuclear protein import [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_139091.2	NP_620791.1	nucleoporin p58/p45
XM_006252093.3	XP_006252155.1	nucleoporin p58/p45 isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	nupl1	NP_001025650.1
Mus musculus (house mouse)	Nupl1	NP_733479.1
Canis lupus familiaris (dog)	NUPL1	XP_003433347.1
Rattus norvegicus (Norway rat)	Nupl1	NP_620791.1
Danio rerio (zebrafish)	nupl1	NP_998394.1
Homo sapiens (human)	NUPL1	NP_054808.1
Pan troglodytes (chimpanzee)	NUPL1	XP_001155775.1
Bos taurus (cattle)	NUPL1	NP_001091598.1
Gallus gallus (chicken)	NUPL1	NP_001026000.1

Gene Ontology
Bibliography

Related articles in PubMed

Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution.
Sharma A, Solmaz SR, Blobel G, Mel??k I
The Journal of biological chemistry290(30)18370-8(2015 Jul)

Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex.
Koh J, Blobel G
Cell161(6)1361-73(2015 Jun)

Regulation of mRNA trafficking by nuclear pore complexes.
Bonnet A, Palancade B
Genes5(3)767-91(2014 Sep)

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.
Ulrich A, Partridge JR, Schwartz TU
Molecular biology of the cell25(9)1484-92(2014 May)

Molecular architecture of the transport channel of the nuclear pore complex.
Solmaz SR, Chauhan R, Blobel G, Mel??k I
Cell147(3)590-602(2011 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we carried out solution analysis utilizing the entire ordered regions of Nup62, Nup54, and Nup58, and demonstrate that they form a dynamic "triple complex"
Title: Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution.

A 1:1:1 stoichiometry of the Nup62 complex, where Nup54 is central with direct binding to Nup62 and Nup58.
Title: The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.

Study reports the crystal structures of the Nup54-Nup58 and Nup62-Nup54 interacting domains and reconstruct the molecular architecture of the NPC transport channel.
Title: Molecular architecture of the transport channel of the nuclear pore complex.

crystal structure of alpha-helical region of Nup58/45; we identified distinct tetramers, each consisting of two antiparallel hairpin dimers [Nup58, Nup45]
Title: Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding.

The following Nup58 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nup58 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02141	NM_139091.2 Latest version!	Rattus norvegicus nucleoporin 58 (Nup58), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa36749	XM_006252093.3 Latest version!	Rattus norvegicus nucleoporin 58 (Nup58), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nup58 ( NM_139091.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620791.1 Rattus norvegicus nucleoporin 58 (Nup58), mRNA.

Price & Availability↑

CloneID	ORa02141
Clone ID Related Accession (Same CDS sequence)	NM_139091.2
Accession Version	NM_139091.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	nucleoporin p58/p45
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085690.1. On or before Jul 25, 2007 this sequence version replaced NM_139092.1, NM_139091.1. ##Evidence-Data-START## Transcript exon combination :: BC085690.1, U63839.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCACGG GGTTCTCCTT TGGGTCCGGG ACCCTCGGCT CCACCACTGT GGCCCCCGGC 
GGCACCGGCA CAGGCAGCGG ATTCTCCTTC GGCGCGTCCA GCACACCTTC TGTGGGGCTC 
AACTTCGGAA CTCTCGGAAG CTCTGCGACA CCAGCATCTA CATCTACTTC TGCCAGTGGT 
TTTGGAACAG GACTCTTTGG ATCTAAGCCT GGCACTGGAT TCACTCTAGG AGGAACAAGT 
GCAGGAACAA CAGCTACTAC ATCTGCATCT ACAACAGGCT TTAGTTTAGG ATTCAGTAAA 
CCTGCAGCAT CTGCCACACC ATTTGCCCTG CCCGTCACTT CTACCACAGC TAGTGGTCTT 
ACTCTCTCGT CTGCTCTGAC ATCAGCTCCA GCAGCATCCA CAGGATTTAC GTTGAATAAC 
TTGGGAGCAA CACCAGCCAC AACTACAGCA GCATCAACAG GACTTTCCTT AGGGGGGGCC 
TTAGCTGGTT TGGGAGGTTC ACTTTTCCAG AGTGGAAACA CAGCAACATC AGGTCTCGGA 
CAGAATGCTT TAAGCTTGTC TCTGGGGACT GCAACACCTA CTTCAGCAGC CAGCAGTGAA 
GGCCTTGGTG GTATAGATTT TAGTACCTCA TCAGATAAAA AGAGTGATAA AACGGGAACA 
AGGCCAGAGG ATAGCAAAGC CCTGAAAGAT GAAAACCTTC CTCCTGTCAT CTGTCAGGAT 
GTTGAGAATC TCCAGAAATT TGTCAAGGAA CAAAAACAAG TCCAAGAAGA AATTAGTCGA 
ATGTCTTCCA AAGCAATGCT TAAAGTCCAG GAGGACATCA AGGCCCTGAA GCAGCTCCTG 
TCATTGGCTG CTAGTGGGTT GCAGAGGAAC ACACTCAATA TTGACAAACT GAAGTTAGAA 
ACTGCTCAGG AGTTAAAGAA TGCGGAAATA GCTTTAAGAA CCCAGAAAAC ACCACCTGGA 
CTCCAACATG AAAATACAGC TCCTGCTGAC TACTTCAGAG TCTTGGTTCA GCAATTTGAG 
GTACAGCTTC AGCAGTACAG GCAGCAGATT GAAGAACTAG AAAACCATCT TGCCACTCAA 
GCAAACAATT CACATATAAC TCCGCAAGAC TTATCAATGG CTATGCAGAA AATTTATCAA 
ACATTTGTAG CTTTAGCTGC ACAACTTCAG TCCATTCATG AAAATGTCAA GGTGCTTAAA 
GAACAGTATC TCAGCTACAG AAAAATGTTT TTGGGTGATG CTGGGGATGT GTTTGAAGCC 
AGGAGAACAG AAGCCAAGAA GTGGCAGAAT GCACCCAGAG TTACTACTGG ACCCACGCCT 
TTCAGCACCA TGCCAAACGC AGCAGCCGTT GCCATGGCTG CAACACTTAC ACAGCAGCAA 
CAGCCTGCTA CAGGGCCACA GCCGTCTCTG GGAGTTAGTT TTGGAACGCC ATTCGGCTCA 
GGTATTGGCA CTGGCTTGCA ATCAAGTGGC TTAGGTTCTT CAAACCTTGG AGGATTTGGA 
ACTAGCTCTG GTTTCGGATG CGGTACCACA GGGGCCTCCA CATTTGGATT TGGAACAACA 
GATAAACCCT CAGGAAGTCT TAGTGCAGGC TTTGGCAGCT CAAGTACGTC TGGGTTTAAC 
TTCAGCAATC CTGGCATCAC GGCATCAGCT GGTTTGACAT TTGGGGTGTC CAATCCTGCG 
TCTGCGGGGT TTGGAACAGG AGGACAACTC CTTCAGTTGA AGAGACCTCC CGCTGGAAAC 
AAAAGAGGAA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620791.1
CDS	86..1843
Translation	MATGFSFGSGTLGSTTVAPGGTGTGSGFSFGASSTPSVGLNFGTLGSSATPASTSTSASGFGTGLFGSKPGTGFTLGGTSAGTTATTSASTTGFSLGFSKPAASATPFALPVTSTTASGLTLSSALTSAPAASTGFTLNNLGATPATTTAASTGLSLGGALAGLGGSLFQSGNTATSGLGQNALSLSLGTATPTSAASSEGLGGIDFSTSSDKKSDKTGTRPEDSKALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAASGLQRNTLNIDKLKLETAQELKNAEIALRTQKTPPGLQHENTAPADYFRVLVQQFEVQLQQYRQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLSYRKMFLGDAGDVFEARRTEAKKWQNAPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCGTTGASTFGFGTTDKPSGSLSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGGQLLQLKRPPAGNKRGKR

Target ORF information:

RefSeq Version	NM_139091.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nucleoporin 58 (Nup58), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139091.2

ORF Insert Sequence:

ATGGCCACGG GGTTCTCCTT TGGGTCCGGG ACCCTCGGCT CCACCACTGT GGCCCCCGGC 
GGCACCGGCA CAGGCAGCGG ATTCTCCTTC GGCGCGTCCA GCACACCTTC TGTGGGGCTC 
AACTTCGGAA CTCTCGGAAG CTCTGCGACA CCAGCATCTA CATCTACTTC TGCCAGTGGT 
TTTGGAACAG GACTCTTTGG ATCTAAGCCT GGCACTGGAT TCACTCTAGG AGGAACAAGT 
GCAGGAACAA CAGCTACTAC ATCTGCATCT ACAACAGGCT TTAGTTTAGG ATTCAGTAAA 
CCTGCAGCAT CTGCCACACC ATTTGCCCTG CCCGTCACTT CTACCACAGC TAGTGGTCTT 
ACTCTCTCGT CTGCTCTGAC ATCAGCTCCA GCAGCATCCA CAGGATTTAC GTTGAATAAC 
TTGGGAGCAA CACCAGCCAC AACTACAGCA GCATCAACAG GACTTTCCTT AGGGGGGGCC 
TTAGCTGGTT TGGGAGGTTC ACTTTTCCAG AGTGGAAACA CAGCAACATC AGGTCTCGGA 
CAGAATGCTT TAAGCTTGTC TCTGGGGACT GCAACACCTA CTTCAGCAGC CAGCAGTGAA 
GGCCTTGGTG GTATAGATTT TAGTACCTCA TCAGATAAAA AGAGTGATAA AACGGGAACA 
AGGCCAGAGG ATAGCAAAGC CCTGAAAGAT GAAAACCTTC CTCCTGTCAT CTGTCAGGAT 
GTTGAGAATC TCCAGAAATT TGTCAAGGAA CAAAAACAAG TCCAAGAAGA AATTAGTCGA 
ATGTCTTCCA AAGCAATGCT TAAAGTCCAG GAGGACATCA AGGCCCTGAA GCAGCTCCTG 
TCATTGGCTG CTAGTGGGTT GCAGAGGAAC ACACTCAATA TTGACAAACT GAAGTTAGAA 
ACTGCTCAGG AGTTAAAGAA TGCGGAAATA GCTTTAAGAA CCCAGAAAAC ACCACCTGGA 
CTCCAACATG AAAATACAGC TCCTGCTGAC TACTTCAGAG TCTTGGTTCA GCAATTTGAG 
GTACAGCTTC AGCAGTACAG GCAGCAGATT GAAGAACTAG AAAACCATCT TGCCACTCAA 
GCAAACAATT CACATATAAC TCCGCAAGAC TTATCAATGG CTATGCAGAA AATTTATCAA 
ACATTTGTAG CTTTAGCTGC ACAACTTCAG TCCATTCATG AAAATGTCAA GGTGCTTAAA 
GAACAGTATC TCAGCTACAG AAAAATGTTT TTGGGTGATG CTGGGGATGT GTTTGAAGCC 
AGGAGAACAG AAGCCAAGAA GTGGCAGAAT GCACCCAGAG TTACTACTGG ACCCACGCCT 
TTCAGCACCA TGCCAAACGC AGCAGCCGTT GCCATGGCTG CAACACTTAC ACAGCAGCAA 
CAGCCTGCTA CAGGGCCACA GCCGTCTCTG GGAGTTAGTT TTGGAACGCC ATTCGGCTCA 
GGTATTGGCA CTGGCTTGCA ATCAAGTGGC TTAGGTTCTT CAAACCTTGG AGGATTTGGA 
ACTAGCTCTG GTTTCGGATG CGGTACCACA GGGGCCTCCA CATTTGGATT TGGAACAACA 
GATAAACCCT CAGGAAGTCT TAGTGCAGGC TTTGGCAGCT CAAGTACGTC TGGGTTTAAC 
TTCAGCAATC CTGGCATCAC GGCATCAGCT GGTTTGACAT TTGGGGTGTC CAATCCTGCG 
TCTGCGGGGT TTGGAACAGG AGGACAACTC CTTCAGTTGA AGAGACCTCC CGCTGGAAAC 
AAAAGAGGAA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nup58 ( XM_006252093.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252155.1 Rattus norvegicus nucleoporin 58 (Nup58), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36749
Clone ID Related Accession (Same CDS sequence)	XM_006252093.3
Accession Version	XM_006252093.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	nucleoporin p58/p45 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252093.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACGG GGTTCTCCTT TGGGTCCGGG ACCCTCGGCT CCACCACTGT GGCCCCCGGC 
GGCACCGGCA CAGGCAGCGG ATTCTCCTTC GGCGCGTCCA GCACACCTTC TGTGGGGCTC 
AACTTCGGAA CTCTCGGAAG CTCTGCGACA CCAGCATCTA CATCTACTTC TGCCAGTGGT 
TTTGGAACAG GACTCTTTGG ATCTAAGCCT GGCACTGGAT TCACTCTAGG AGGAACAAGT 
GCAGGAACAA CAGCTACTAC ATCTGCATCT ACAACAGGCT TTAGTTTAGG ATTCAGTAAA 
CCTGCAGCAT CTGCCACACC ATTTGCCCTG CCCGTCACTT CTACCACAGC TAGTGGTCTT 
ACTCTCTCGT CTGCTCTGAC ATCAGCTCCA GCAGCATCCA CAGGATTTAC GTTGAATAAC 
TTGGGAGCAA CACCAGCCAC AACTACAGCA GCATCAACAG GACTTTCCTT AGGGGGGGCC 
TTAGCTGGTT TGGGAGGTTC ACTTTTCCAG AGTGGAAACA CAGCAACATC AGGTCTCGGA 
CAGAATGCTT TAAGCTTGTC TCTGGGGACT GCAACACCTA CTTCAGCAGC CAGCAGTGAA 
GGCCTTGGTG GTATAGATTT TAGTACCTCA TCAGATAAAA AGAGTGATAA AACGGGAACA 
AGGCCAGAGG ATAGCAAAGC CCTGAAAGAT GAAAACCTTC CTCCTGTCAT CTGTCAGGAT 
GTTGAGAATC TCCAGAAATT TGTCAAGGAA CAAAAACAAG TCCAAGAAGA AATTAGTCGA 
ATGTCTTCCA AAGCAATGCT TAAAGTCCAG GAGGACATCA AGGCCCTGAA GCAGCTCCTG 
TCATTGGCTG CTAGTGGGTT GCAGAGGAAC ACACTCAATA TTGACAAACT GAAGTTAGAA 
ACTGCTCAGG AGTTAAAGAA TGCGGAAATA GCTTTAAGAA CCCAGAAAAC ACCACCTGGA 
CTCCAACATG AAAATACAGC TCCTGCTGAC TACTTCAGAG TCTTGGTTCA GCAATTTGAG 
GTACAGCTTC AGCAGTACAG GCAGCAGATT GAAGAACTAG AAAACCATCT TGCCACTCAA 
GCAAACAATT CACATATAAC TCCGCAAGAC TTATCAATGG CTATGCAGAA AATTTATCAA 
ACATTTGTAG CTTTAGCTGC ACAACTTCAG TCCATTCATG AAAATGTCAA GGTGCTTAAA 
GAACAGTATC TCAGCTACAG AAAAATGTTT TTGGGTGATG CTGGGGATGT GTTTGAAGCC 
AGGAGAACAG AAGCCAAGAA GTGGCAGAAT GCACCCAGAG TTACTACTGG ACCCACGCCT 
TTCAGCACCA TGCCAAACGC AGCAGCCGTT GCCATGGCTG CAACACTTAC ACAGCAGCAA 
CAGCCTGCTA CAGGGCCACA GCCGTCTCTG GGAGTTAGTT TTGGAACGCC ATTCGGCTCA 
GGTATTGGCA CTGGCTTGCA ATCAAGTGGC TTAGGTTCTT CAAACCTTGG AGGATTTGGA 
ACTAGCTCTG GTTTCGGATG CGGTACCACA GGGGCCTCCA CATTTGGATT TGGAACAACA 
GATAAACCCT CAGGAAGTCT TAGTGCAGGC CAAAAATCGC ATGTTTTAAC TGGATTTCGC 
AAACCTAGTG TTACGGAAAC TAATGAACTA GGAAGAAAAA TCCAATTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252155.1
CDS	195..1865
Translation	MATGFSFGSGTLGSTTVAPGGTGTGSGFSFGASSTPSVGLNFGTLGSSATPASTSTSASGFGTGLFGSKPGTGFTLGGTSAGTTATTSASTTGFSLGFSKPAASATPFALPVTSTTASGLTLSSALTSAPAASTGFTLNNLGATPATTTAASTGLSLGGALAGLGGSLFQSGNTATSGLGQNALSLSLGTATPTSAASSEGLGGIDFSTSSDKKSDKTGTRPEDSKALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAASGLQRNTLNIDKLKLETAQELKNAEIALRTQKTPPGLQHENTAPADYFRVLVQQFEVQLQQYRQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLSYRKMFLGDAGDVFEARRTEAKKWQNAPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCGTTGASTFGFGTTDKPSGSLSAGQKSHVLTGFRKPSVTETNELGRKIQF

Target ORF information:

RefSeq Version	XM_006252093.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nucleoporin 58 (Nup58), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252093.3

ORF Insert Sequence:

ATGGCCACGG GGTTCTCCTT TGGGTCCGGG ACCCTCGGCT CCACCACTGT GGCCCCCGGC 
GGCACCGGCA CAGGCAGCGG ATTCTCCTTC GGCGCGTCCA GCACACCTTC TGTGGGGCTC 
AACTTCGGAA CTCTCGGAAG CTCTGCGACA CCAGCATCTA CATCTACTTC TGCCAGTGGT 
TTTGGAACAG GACTCTTTGG ATCTAAGCCT GGCACTGGAT TCACTCTAGG AGGAACAAGT 
GCAGGAACAA CAGCTACTAC ATCTGCATCT ACAACAGGCT TTAGTTTAGG ATTCAGTAAA 
CCTGCAGCAT CTGCCACACC ATTTGCCCTG CCCGTCACTT CTACCACAGC TAGTGGTCTT 
ACTCTCTCGT CTGCTCTGAC ATCAGCTCCA GCAGCATCCA CAGGATTTAC GTTGAATAAC 
TTGGGAGCAA CACCAGCCAC AACTACAGCA GCATCAACAG GACTTTCCTT AGGGGGGGCC 
TTAGCTGGTT TGGGAGGTTC ACTTTTCCAG AGTGGAAACA CAGCAACATC AGGTCTCGGA 
CAGAATGCTT TAAGCTTGTC TCTGGGGACT GCAACACCTA CTTCAGCAGC CAGCAGTGAA 
GGCCTTGGTG GTATAGATTT TAGTACCTCA TCAGATAAAA AGAGTGATAA AACGGGAACA 
AGGCCAGAGG ATAGCAAAGC CCTGAAAGAT GAAAACCTTC CTCCTGTCAT CTGTCAGGAT 
GTTGAGAATC TCCAGAAATT TGTCAAGGAA CAAAAACAAG TCCAAGAAGA AATTAGTCGA 
ATGTCTTCCA AAGCAATGCT TAAAGTCCAG GAGGACATCA AGGCCCTGAA GCAGCTCCTG 
TCATTGGCTG CTAGTGGGTT GCAGAGGAAC ACACTCAATA TTGACAAACT GAAGTTAGAA 
ACTGCTCAGG AGTTAAAGAA TGCGGAAATA GCTTTAAGAA CCCAGAAAAC ACCACCTGGA 
CTCCAACATG AAAATACAGC TCCTGCTGAC TACTTCAGAG TCTTGGTTCA GCAATTTGAG 
GTACAGCTTC AGCAGTACAG GCAGCAGATT GAAGAACTAG AAAACCATCT TGCCACTCAA 
GCAAACAATT CACATATAAC TCCGCAAGAC TTATCAATGG CTATGCAGAA AATTTATCAA 
ACATTTGTAG CTTTAGCTGC ACAACTTCAG TCCATTCATG AAAATGTCAA GGTGCTTAAA 
GAACAGTATC TCAGCTACAG AAAAATGTTT TTGGGTGATG CTGGGGATGT GTTTGAAGCC 
AGGAGAACAG AAGCCAAGAA GTGGCAGAAT GCACCCAGAG TTACTACTGG ACCCACGCCT 
TTCAGCACCA TGCCAAACGC AGCAGCCGTT GCCATGGCTG CAACACTTAC ACAGCAGCAA 
CAGCCTGCTA CAGGGCCACA GCCGTCTCTG GGAGTTAGTT TTGGAACGCC ATTCGGCTCA 
GGTATTGGCA CTGGCTTGCA ATCAAGTGGC TTAGGTTCTT CAAACCTTGG AGGATTTGGA 
ACTAGCTCTG GTTTCGGATG CGGTACCACA GGGGCCTCCA CATTTGGATT TGGAACAACA 
GATAAACCCT CAGGAAGTCT TAGTGCAGGC CAAAAATCGC ATGTTTTAAC TGGATTTCGC 
AAACCTAGTG TTACGGAAAC TAATGAACTA GGAAGAAAAA TCCAATTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution.
The Journal of biological chemistry290(30)18370-8(2015 Jul)
Sharma A,Solmaz SR,Blobel G,Mel??k I

Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex.
Cell161(6)1361-73(2015 Jun)
Koh J,Blobel G

Regulation of mRNA trafficking by nuclear pore complexes.
Genes5(3)767-91(2014 Sep)
Bonnet A,Palancade B

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.
Molecular biology of the cell25(9)1484-92(2014 May)
Ulrich A,Partridge JR,Schwartz TU

Molecular architecture of the transport channel of the nuclear pore complex.
Cell147(3)590-602(2011 Oct)
Solmaz SR,Chauhan R,Blobel G,Mel??k I

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Nup58 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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