Abcc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcc1
Entrez Gene ID	24565
Full Name	ATP binding cassette subfamily C member 1
Synonyms	Abcc1a,Avcc1a,Mrp,Mrp1
General protein information	Preferred Names ATP binding cassette subfamily C member 1 Names multidrug resistance-associated protein 1 ATP-binding cassette sub-family C ( CFTR/MRP) member 1a ATP-binding cassette sub-family C member 1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 ATP-binding cassette, sub-family C, member 1-like ATP-binding cassette, subfamily C (CFTR/MRP), member 1 LTC4 transporter leukotriene C(4) transporter multidrug resistance protein 1 multidrug resistance-associated protein 1-like multiple drug resistance-associated protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q11
Summary	ATP-binding cassette (ABC) multiple drug resistance protein involved in the release of glutathione synthase during oxidative stress [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022281.2	NP_071617.2	multidrug resistance-associated protein 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	abcc1	XP_001341895.3
Caenorhabditis elegans (roundworm)	mrp-1	NP_001033553.1
Arabidopsis thaliana (thale cress)	MRP5	NP_171908.1
Oryza sativa (rice)	Os03g0142800	NP_001048934.1
Canis lupus familiaris (dog)	ABCC1	NP_001002971.1
Bos taurus (cattle)	ABCC1	NP_776648.1
Homo sapiens (human)	ABCC1	NP_004987.2
Pan troglodytes (chimpanzee)	ABCC1	XP_001145351.1
Rattus norvegicus (Norway rat)	Abcc1	NP_071617.2
Gallus gallus (chicken)	ABCC1	NP_001012540.1
Mus musculus (house mouse)	Abcc1	NP_032602.1
Caenorhabditis elegans (roundworm)	mrp-2	NP_508121.1

Gene Ontology
Bibliography

Related articles in PubMed

MRP-1 and BCRP Promote the Externalization of Phosphatidylserine in Oxalate-treated Renal Epithelial Cells: Implications for Calcium Oxalate Urolithiasis.
Li Y, Yu S, Gan X, Zhang Z, Wang Y, Wang Y, An R
Urology107271.e9-271.e17(2017 Sep)

Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.
Ibbotson K, Yell J, Ronaldson PT
Fluids and barriers of the CNS14(1)6(2017 Mar)

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.
Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G
Pharmaceutical research32(9)2973-82(2015 Sep)

Accumulation of murine amyloid-? mimics early Alzheimer's disease.
Krohn M, Bracke A, Avchalumov Y, Schumacher T, Hofrichter J, Paarmann K, Fr?hlich C, Lange C, Br?ning T, von Bohlen Und Halbach O, Pahnke J
Brain : a journal of neurology138(Pt 8)2370-82(2015 Aug)

Down-Regulation of MRP1 Expression in C6/VP16 Cells by Chitosan-MRP1-siRNA Nanoparticles.
Xu H, Nie X, Wu L, Zhu X, Yi W, Huang S
Cell biochemistry and biophysics72(1)227-33(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data of this study show increased Abcc1, Abcc2, and Abcc4 mRNA expression at the BBB in response to H/R stress and that Abcc gene expression is regulated by Nrf2 signaling.
Title: Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.

MRP1 is downregulated in glioma cells by chitosan-MRP1 siRNA nanoparticles
Title: Down-Regulation of MRP1 Expression in C6/VP16 Cells by Chitosan-MRP1-siRNA Nanoparticles.

The number of MRP1-positive cells in the cortex and hippocampus was also significantly increased in amygdale kindling rats.
Title: Multidrug resistance-associated protein 1 decreases the concentrations of antiepileptic drugs in cortical extracellular fluid in amygdale kindling rats.

Sonication enhanced sensitivity of glioma tumor cells to doxorubicin by down-regulating the expressions of p-glycoprotein and multidrug resistance protein 1.
Title: Low intensity ultrasound promotes the sensitivity of rat brain glioma to Doxorubicin by down-regulating the expressions of p-glucoprotein and multidrug resistance protein 1 in vitro and in vivo.

Xifeng Capsule used alone or combined with carbamazepine can effectively inhibit MRP1 expression in hippocampus and cortex of epileptic rats.
Title: [Effects of Chinese herbal medicine Xifeng Capsule on multidrug resistance-associated protein 1 expression in hippocampus and cortex of rats with lithium-pilocarpine-induced epilepsy].

The following Abcc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12316	NM_022281.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 1 (Abcc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcc1 ( NM_022281.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071617.2 Rattus norvegicus ATP binding cassette subfamily C member 1 (Abcc1), mRNA.

Price & Availability↑

CloneID	ORa12316
Clone ID Related Accession (Same CDS sequence)	NM_022281.2
Accession Version	NM_022281.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF487549.1. On or before Dec 17, 2003 this sequence version replaced XM_222527.2, NM_022281.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF487549.1, AY170916.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCTGA GCAGCTTCTG CAGCTCTGAT GGCTCCGATC CGCTCTGGGA TTGGAATGTC 
ACATGGCACA CCAGCAACCC TGACTTTACC AAGTGCTTTC AGAATACGGT CCTCACATGG 
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCCTCTATCT CTCTCGACAT 
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAGCCA AAACTGCCTT AGGATTCTTT 
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAATG 
CTCCTAGCCC CGGTGCTACT GGTCAGCCCG ACACTGCTAG GCATCACCAT GCTGCTCGCC 
ACCTTTTTAA TTCAGTTTGA GCGAAGGAAA GGAGTCCAGT CCTCAGGGAT AATGCTTACT 
TTCTGGCTTG TAGCCCTACT CTGCGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC 
TTAAAAAAGG ATGCTCAAGT GGACATGTTT CGAGATTCTG CATTCTATCT CTACTTCACC 
CTCGTGTTCA TTCAGCTTGT GCTGTCCTGC TTCTCAGACA GCTCACCCTT GTTCTCTGAA 
ACTGTCCGTG ACCCGAATCC ATGTCCAGAA TCGAGTGCCT CTTTTCTTTC CAGGATCACT 
TTTTGGTGGA TTACAGGGAT GATGGTGCAG GGCTACCGCC AGCCCCTGAA GAGCAGTGAC 
CTCTGGTCAT TGAATAAAGA GGACACGTCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC 
TGGAAGAAGG AATGTGTTAA GTCGAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC 
AAAGATCCCA CCAAGCCTAA GGGAAGTTCT CAGTTGGATG TGAATGAGGA AGTGGAGGCA 
CTGATTGTCA AGTCATCCCA CAAGGACCGG GACCCCTCTC TGTTCAAGGT GTTGTACAAG 
ACCTTTGGGC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG 
TTTGCTGGCC CTGAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCCCCT 
GACTGGCAGG GCTACTTGTA CACAGCACTG CTGTTTGTCA GTGCCTGTCT GCAGACACTG 
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCACCGGCA TGCGCATCAA GACTGCTGTG 
GTGGGTGCTG TTTACCGCAA GGCTCTTGTG ATCACCAATT CAGCTAGAAA ATCGTCCACA 
GTTGGAGAGA TTGTCAACCT CATGTCCGTG GATGCCCAGC GCTTCATGGA CTTGGCCACG 
TATATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCACCC TAGCCCTCTA CTTCCTGTGG 
CTGAACCTGG GCCCTTCTGT GCTGGCTGGG GTGGCTGTTA TGATCCTCAT GGTGCCCTTC 
AATGCTGTGA TGGCCATGAA GACCAAGACT TACCAGGTGG CACACATGAA GAGCAAAGAC 
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTACTCAA ATTGTACGCC 
TGGGAGCTGG CTTTCCAGGA CAAAGTTATG AACATCAGGC AGGAGGAGCT GAAGGTGCTG 
AAGAAATCCG CCTACCTGGC GGCTGTGGGC ACATTCACAT GGGTTTGCAC ACCTTTCCTG 
GTGGCTCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGACG AGAAGAACAT CCTAGATGCA 
AAGAAAGCCT TTGTATCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTA 
CCCATGGTCA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATCTTT 
CTGTCTCACG AGGAGCTGGA GCCAGACAGC ATCGAGCGAT GGTCGATCAA GGATGGTGGA 
GGGATGAATA GCATCACTGT GAAGAATGCA ACCTTCACTT GGGCCAGGGA TGAACCTCCC 
ACACTGAATG GCATCACCTT CGCCATCCCT GATGGAGCCC TTGTGGCCGT GGTGGGCCAG 
GTAGGCTGTG GGAAGTCATC TCTGCTGTCA GCCCTGCTGG CTGAGATGGA CAAAGTGGAG 
GGACATGTGA CTCTCAAGGG CTCCGTGGCC TATGTGCCCC AGCAGGCCTG GATTCAGAAT 
GACTCTCTCC GAGAGAACAT ACTGTTTGGG CGCCCCCTGC AGGAACATTG CTACAAGGCG 
GTGATGGAAG CCTGTGCCCT CCTTCCGGAT TTGGAAATCC TTCCCAGTGG GGACCTCACA 
GAGATTGGTG AGAAGGGTGT GAACCTGTCG GGGGGCCAGA AGCAGCGTGT GAGCCTGGCT 
CGGGCTGTGT ATTGTAACTC TGACATCTAC CTCTTGGACG ACCCCCTCTC GGCTGTGGAT 
GCACATGTTG GGAAGCACAT CTTTGAGAAG GTGGTGGGTC CCATGGGCCT ACTGAAGAAC 
AAGACACGGA TCCTGGTCAC CCATGGTATC AGCTACCTGC CCCAAGTGGA TGTCATCATT 
GTCATGAGTG GCGGCAAGAT CTCAGAGATG GGATCTTATC AGGAGCTGCT AGACCGGGAT 
GGGGCCTTTG CTGAGTTCGT GCGCACCTAT GCCAACACTG AGCAGGACCT GGCTTCAGAG 
GATGACAGTA AGAATGGTGT CAGTGGTTTA GGGAAGGAGT CAAAGCCGGT GGAAAATGGG 
ATACTGGTGA CAGACGCAGT AGGGAAGCCC CTGCAGAGGC ATCTCAGCAA CTCTTCTTCC 
CACAGTGTGG TTACTAACCA GCAGCACAGC AGCACAGCCG AGCTGCAGAA GTCTGGAGTT 
AAGGAGGAGA CTTGGAAGCT GATGGAAGCA GACAAGGCCC AGACAGGGCA GGTGAAGCTT 
TCCGTGTACT GGAACTACAT GAAGGCCATT GGCCTCTGCA TCTCCTTCTT GAGTATCTTC 
CTTTTCCTGT GCAATCATGT ATCTGCACTG GCTTCTAACT ATTGGCTGAG TCTCTGGACA 
GATGACCGCC CTGCTGTCAA TGGGACTCAG GAGAACAGGA ATTTTCGACT AAGTGTCTAT 
GGGGCCTTGG GCATCTTGCA AGGTGTGGCA GTATTTGGCT ATTCCATGGC TGTGTCCATT 
GGGGGCATCT TTGCCTCCCG TCGCCTGCAC CTAGACCTGC TACAGAATGT CCTGCGATCA 
CCCATGAGTT TCTTTGAGCG TACACCCAGT GGGAACCTAG TGAACCGATT CTCCAAGGAG 
TTGGACACAG TGGACTCCAT GATCCCGCAG GTCATCAAGA TGTTCATGGG TTCACTCTTC 
AGTGTCATTG GAGCTGTCAT CATCATCCTA CTGGCTACGC CCATTGCCGC AGTCATCATC 
CCACCCTTGG GTCTGGTTTA CTTCTTTGTG CAGAGGTTCT ATGTGGCCTC CTCTCGACAG 
CTGAAGCGCC TGGAGTCTGT CAGTCGTTCC CCTGTGTACT CACACTTCAA TGAGACCTTG 
CTGGGGGTCA GTGTCATCCG TGCCTTTGAG GAACAGGAGC GCTTCATTCG CCAAAGTGAC 
CTGAAAGTAG ATGAGAACCA GAAGGCCTAC TACCCCAGCA TTGTGGCCAA CAGGTGGCTT 
GCTGTGCGCC TGGAGTGTGT GGGCAACTGC ATTGTGCTGT TTGCTGCCCT TTTCGCAGTC 
ATCTCCCGGC ATAGCCTCAG TGCTGGCTTG GTGGGTCTCT CTGTGTCTTA CTCACTGCAG 
ATAACTGCAT ACTTGAACTG GCTAGTTCGA ATGTCCTCTG AGATGGAGAC CAACATTGTG 
GCAGTGGAGA GACTGAAGGA ATATTCTGAA ACGGAGAAGG AGGCTTCTTG GCAAATCCAA 
GAGACAGCTC CACCCAGCAC CTGGCCCCAT TCAGGCCGTG TAGAGTTCCG GGATTACTGC 
TTGAGGTATC GAGAAGACTT GGACTTGGTT CTCAAGCACA TAAATGTCAC CATTGAGGGT 
GGAGAAAAGG TTGGTATTGT GGGTCGTACA GGAGCTGGGA AATCATCTCT CACCCTGGGT 
TTGTTCCGGA TCAATGAGTC TGCAGAAGGG GAGATCATCA TTGATGGGAT AAACATTGCT 
AAGATTGGCC TGCACAACCT GCGCTTCAAG ATCACCATCA TTCCACAGGA TCCTGTTTTG 
TTCTCGGGTT CCCTCCGCAT GAACCTGGAC CCTTTCAGTC AGTATTCTGA TGAAGAAGTC 
TGGATGGCTC TGGAGCTTGC TCACCTGAAG GGCTTTGTGT CAGCCTTGCC TGACAAGCTG 
AACCATGAGT GTGCAGAAGG TGGAGAGAAT CTGAGTGTGG GGCAGCGACA GCTTGTGTGC 
CTGGCCCGGG CTTTGCTGAG GAAGACAAAG ATTCTAGTGT TGGACGAGGC TACAGCAGCT 
GTGGATCTGG AGACAGATGA CCTTATTCAG TCCACCATCC GGACGCAGTT TGAAGACAGT 
ACTGTGCTCA CTATTGCTCA TCGGCTGAAT ACCATAATGG ACTATACAAG GGTGATTGTC 
CTGGACAAAG GAGAAATTCG GGAGTGTGGT GCACCCTCTG AGCTCCTGCA GCAAAGAGGC 
GTCTTCTATA GCATGGCCAA GGATGCTGGC TTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071617.2
CDS	40..4638
Translation	MALSSFCSSDGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFLYLSRHDRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGMLLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDMFRDSAFYLYFTLVFIQLVLSCFSDSSPLFSETVRDPNPCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENGILVTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAELQKSGVKEETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQRGVFYSMAKDAGLV

Target ORF information:

RefSeq Version	NM_022281.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 1 (Abcc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022281.2

ORF Insert Sequence:

ATGGCGCTGA GCAGCTTCTG CAGCTCTGAT GGCTCCGATC CGCTCTGGGA TTGGAATGTC 
ACATGGCACA CCAGCAACCC TGACTTTACC AAGTGCTTTC AGAATACGGT CCTCACATGG 
GTGCCTTGTT TCTACCTCTG GTCCTGTTTC CCCCTCTACT TCCTCTATCT CTCTCGACAT 
GACCGGGGCT ACATCCAGAT GACACACCTC AACAAAGCCA AAACTGCCTT AGGATTCTTT 
CTGTGGATCA TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TCAGGGAATG 
CTCCTAGCCC CGGTGCTACT GGTCAGCCCG ACACTGCTAG GCATCACCAT GCTGCTCGCC 
ACCTTTTTAA TTCAGTTTGA GCGAAGGAAA GGAGTCCAGT CCTCAGGGAT AATGCTTACT 
TTCTGGCTTG TAGCCCTACT CTGCGCCCTT GCCATCTTGA GATCTAAGAT CATCTCTGCC 
TTAAAAAAGG ATGCTCAAGT GGACATGTTT CGAGATTCTG CATTCTATCT CTACTTCACC 
CTCGTGTTCA TTCAGCTTGT GCTGTCCTGC TTCTCAGACA GCTCACCCTT GTTCTCTGAA 
ACTGTCCGTG ACCCGAATCC ATGTCCAGAA TCGAGTGCCT CTTTTCTTTC CAGGATCACT 
TTTTGGTGGA TTACAGGGAT GATGGTGCAG GGCTACCGCC AGCCCCTGAA GAGCAGTGAC 
CTCTGGTCAT TGAATAAAGA GGACACGTCA GAAGAAGTGG TACCTGTGCT GGTGAATAAC 
TGGAAGAAGG AATGTGTTAA GTCGAGGAAG CAGCCTGTAC GGATTGTGTA TGCCCCTCCC 
AAAGATCCCA CCAAGCCTAA GGGAAGTTCT CAGTTGGATG TGAATGAGGA AGTGGAGGCA 
CTGATTGTCA AGTCATCCCA CAAGGACCGG GACCCCTCTC TGTTCAAGGT GTTGTACAAG 
ACCTTTGGGC CCTACTTCCT CATGAGCTTC CTGTACAAGG CCCTTCATGA CCTGATGATG 
TTTGCTGGCC CTGAGATCTT GGAATTGATT ATCAACTTCG TGAATGACAG GGAGGCCCCT 
GACTGGCAGG GCTACTTGTA CACAGCACTG CTGTTTGTCA GTGCCTGTCT GCAGACACTG 
GCACTCCACC AGTACTTTCA TATCTGCTTC GTCACCGGCA TGCGCATCAA GACTGCTGTG 
GTGGGTGCTG TTTACCGCAA GGCTCTTGTG ATCACCAATT CAGCTAGAAA ATCGTCCACA 
GTTGGAGAGA TTGTCAACCT CATGTCCGTG GATGCCCAGC GCTTCATGGA CTTGGCCACG 
TATATTAACA TGATCTGGTC AGCCCCTCTG CAAGTCACCC TAGCCCTCTA CTTCCTGTGG 
CTGAACCTGG GCCCTTCTGT GCTGGCTGGG GTGGCTGTTA TGATCCTCAT GGTGCCCTTC 
AATGCTGTGA TGGCCATGAA GACCAAGACT TACCAGGTGG CACACATGAA GAGCAAAGAC 
AACCGAATCA AGCTGATGAA CGAGATCCTC AATGGGATCA AAGTACTCAA ATTGTACGCC 
TGGGAGCTGG CTTTCCAGGA CAAAGTTATG AACATCAGGC AGGAGGAGCT GAAGGTGCTG 
AAGAAATCCG CCTACCTGGC GGCTGTGGGC ACATTCACAT GGGTTTGCAC ACCTTTCCTG 
GTGGCTCTGT CAACCTTTGC TGTCTTTGTG ACTGTGGACG AGAAGAACAT CCTAGATGCA 
AAGAAAGCCT TTGTATCCCT AGCCCTGTTC AATATCTTGC GCTTCCCACT CAACATCCTA 
CCCATGGTCA TCAGCAGCAT TGTGCAGGCC AGCGTGTCCC TCAAGCGTCT CAGGATCTTT 
CTGTCTCACG AGGAGCTGGA GCCAGACAGC ATCGAGCGAT GGTCGATCAA GGATGGTGGA 
GGGATGAATA GCATCACTGT GAAGAATGCA ACCTTCACTT GGGCCAGGGA TGAACCTCCC 
ACACTGAATG GCATCACCTT CGCCATCCCT GATGGAGCCC TTGTGGCCGT GGTGGGCCAG 
GTAGGCTGTG GGAAGTCATC TCTGCTGTCA GCCCTGCTGG CTGAGATGGA CAAAGTGGAG 
GGACATGTGA CTCTCAAGGG CTCCGTGGCC TATGTGCCCC AGCAGGCCTG GATTCAGAAT 
GACTCTCTCC GAGAGAACAT ACTGTTTGGG CGCCCCCTGC AGGAACATTG CTACAAGGCG 
GTGATGGAAG CCTGTGCCCT CCTTCCGGAT TTGGAAATCC TTCCCAGTGG GGACCTCACA 
GAGATTGGTG AGAAGGGTGT GAACCTGTCG GGGGGCCAGA AGCAGCGTGT GAGCCTGGCT 
CGGGCTGTGT ATTGTAACTC TGACATCTAC CTCTTGGACG ACCCCCTCTC GGCTGTGGAT 
GCACATGTTG GGAAGCACAT CTTTGAGAAG GTGGTGGGTC CCATGGGCCT ACTGAAGAAC 
AAGACACGGA TCCTGGTCAC CCATGGTATC AGCTACCTGC CCCAAGTGGA TGTCATCATT 
GTCATGAGTG GCGGCAAGAT CTCAGAGATG GGATCTTATC AGGAGCTGCT AGACCGGGAT 
GGGGCCTTTG CTGAGTTCGT GCGCACCTAT GCCAACACTG AGCAGGACCT GGCTTCAGAG 
GATGACAGTA AGAATGGTGT CAGTGGTTTA GGGAAGGAGT CAAAGCCGGT GGAAAATGGG 
ATACTGGTGA CAGACGCAGT AGGGAAGCCC CTGCAGAGGC ATCTCAGCAA CTCTTCTTCC 
CACAGTGTGG TTACTAACCA GCAGCACAGC AGCACAGCCG AGCTGCAGAA GTCTGGAGTT 
AAGGAGGAGA CTTGGAAGCT GATGGAAGCA GACAAGGCCC AGACAGGGCA GGTGAAGCTT 
TCCGTGTACT GGAACTACAT GAAGGCCATT GGCCTCTGCA TCTCCTTCTT GAGTATCTTC 
CTTTTCCTGT GCAATCATGT ATCTGCACTG GCTTCTAACT ATTGGCTGAG TCTCTGGACA 
GATGACCGCC CTGCTGTCAA TGGGACTCAG GAGAACAGGA ATTTTCGACT AAGTGTCTAT 
GGGGCCTTGG GCATCTTGCA AGGTGTGGCA GTATTTGGCT ATTCCATGGC TGTGTCCATT 
GGGGGCATCT TTGCCTCCCG TCGCCTGCAC CTAGACCTGC TACAGAATGT CCTGCGATCA 
CCCATGAGTT TCTTTGAGCG TACACCCAGT GGGAACCTAG TGAACCGATT CTCCAAGGAG 
TTGGACACAG TGGACTCCAT GATCCCGCAG GTCATCAAGA TGTTCATGGG TTCACTCTTC 
AGTGTCATTG GAGCTGTCAT CATCATCCTA CTGGCTACGC CCATTGCCGC AGTCATCATC 
CCACCCTTGG GTCTGGTTTA CTTCTTTGTG CAGAGGTTCT ATGTGGCCTC CTCTCGACAG 
CTGAAGCGCC TGGAGTCTGT CAGTCGTTCC CCTGTGTACT CACACTTCAA TGAGACCTTG 
CTGGGGGTCA GTGTCATCCG TGCCTTTGAG GAACAGGAGC GCTTCATTCG CCAAAGTGAC 
CTGAAAGTAG ATGAGAACCA GAAGGCCTAC TACCCCAGCA TTGTGGCCAA CAGGTGGCTT 
GCTGTGCGCC TGGAGTGTGT GGGCAACTGC ATTGTGCTGT TTGCTGCCCT TTTCGCAGTC 
ATCTCCCGGC ATAGCCTCAG TGCTGGCTTG GTGGGTCTCT CTGTGTCTTA CTCACTGCAG 
ATAACTGCAT ACTTGAACTG GCTAGTTCGA ATGTCCTCTG AGATGGAGAC CAACATTGTG 
GCAGTGGAGA GACTGAAGGA ATATTCTGAA ACGGAGAAGG AGGCTTCTTG GCAAATCCAA 
GAGACAGCTC CACCCAGCAC CTGGCCCCAT TCAGGCCGTG TAGAGTTCCG GGATTACTGC 
TTGAGGTATC GAGAAGACTT GGACTTGGTT CTCAAGCACA TAAATGTCAC CATTGAGGGT 
GGAGAAAAGG TTGGTATTGT GGGTCGTACA GGAGCTGGGA AATCATCTCT CACCCTGGGT 
TTGTTCCGGA TCAATGAGTC TGCAGAAGGG GAGATCATCA TTGATGGGAT AAACATTGCT 
AAGATTGGCC TGCACAACCT GCGCTTCAAG ATCACCATCA TTCCACAGGA TCCTGTTTTG 
TTCTCGGGTT CCCTCCGCAT GAACCTGGAC CCTTTCAGTC AGTATTCTGA TGAAGAAGTC 
TGGATGGCTC TGGAGCTTGC TCACCTGAAG GGCTTTGTGT CAGCCTTGCC TGACAAGCTG 
AACCATGAGT GTGCAGAAGG TGGAGAGAAT CTGAGTGTGG GGCAGCGACA GCTTGTGTGC 
CTGGCCCGGG CTTTGCTGAG GAAGACAAAG ATTCTAGTGT TGGACGAGGC TACAGCAGCT 
GTGGATCTGG AGACAGATGA CCTTATTCAG TCCACCATCC GGACGCAGTT TGAAGACAGT 
ACTGTGCTCA CTATTGCTCA TCGGCTGAAT ACCATAATGG ACTATACAAG GGTGATTGTC 
CTGGACAAAG GAGAAATTCG GGAGTGTGGT GCACCCTCTG AGCTCCTGCA GCAAAGAGGC 
GTCTTCTATA GCATGGCCAA GGATGCTGGC TTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MRP-1 and BCRP Promote the Externalization of Phosphatidylserine in Oxalate-treated Renal Epithelial Cells: Implications for Calcium Oxalate Urolithiasis.
Urology107271.e9-271.e17(2017 Sep)
Li Y,Yu S,Gan X,Zhang Z,Wang Y,Wang Y,An R

Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.
Fluids and barriers of the CNS14(1)6(2017 Mar)
Ibbotson K,Yell J,Ronaldson PT

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.
Pharmaceutical research32(9)2973-82(2015 Sep)
Bernd A,Ott M,Ishikawa H,Schroten H,Schwerk C,Fricker G

Accumulation of murine amyloid-? mimics early Alzheimer's disease.
Brain : a journal of neurology138(Pt 8)2370-82(2015 Aug)
Krohn M,Bracke A,Avchalumov Y,Schumacher T,Hofrichter J,Paarmann K,Fr?hlich C,Lange C,Br?ning T,von Bohlen Und Halbach O,Pahnke J

Down-Regulation of MRP1 Expression in C6/VP16 Cells by Chitosan-MRP1-siRNA Nanoparticles.
Cell biochemistry and biophysics72(1)227-33(2015 May)
Xu H,Nie X,Wu L,Zhu X,Yi W,Huang S

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Abcc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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