Foxg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Foxg1
Entrez Gene ID	24370
Full Name	forkhead box G1
Synonyms	BF1A,Fkhl1,RATBF1A
General protein information	Preferred Names forkhead box G1 Names forkhead box protein G1 BF-1 BF1 brain factor 1 forkhead-like transcription factor BF-1 forkhead-related protein FKHL1 transcription factor BF-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q22
Summary	coordinates many cell survival mechanisms [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012560.2	NP_036692.1	forkhead box protein G1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FOXG1	NP_005240.3
Bos taurus (cattle)	FOXG1	XP_002707820.2
Rattus norvegicus (Norway rat)	Foxg1	NP_036692.1
Xenopus tropicalis (tropical clawed frog)	foxg1	NP_001116933.1
Mus musculus (house mouse)	Foxg1	NP_032267.1
Danio rerio (zebrafish)	foxg1a	NP_571142.1
Pan troglodytes (chimpanzee)	FOXG1	XP_003952518.1
	LOC716287	XP_001106922.2

Gene Ontology
Bibliography

Related articles in PubMed

DNA-binding specificities of human transcription factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J
Cell152(1-2)327-39(2013 Jan)

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.
Miyoshi G, Fishell G
Neuron74(6)1045-58(2012 Jun)

Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain.
Yip DJ, Corcoran CP, Alvarez-Saavedra M, DeMaria A, Rennick S, Mears AJ, Rudnicki MA, Messier C, Picketts DJ
Developmental cell22(4)871-8(2012 Apr)

Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.
Dastidar SG, Narayanan S, Stifani S, D'Mello SR
The Journal of biological chemistry287(18)14749-59(2012 Apr)

Common increase of GATA-3 level in PC-12 cells by three teratogens causing autism spectrum disorders.
Rout UK, Clausen P
Neuroscience research64(2)162-9(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TLE1 cooperates with FoxG1 to promote neuronal survival in a CK2- and PI3K-Akt-dependent manner.
Title: Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.

The antioxidant Trolox attenuates mechanical ventilation-induced diaphragmatic atrophy independent of alterations in Akt regulation of FoxO transcription factors and expression of MAFbx or MuRF-1.
Title: Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB Akt) signalling.

FoxG1 may interact with AR in vivo, thereby targeting its repressor function specifically to sex hormone signaling.
Title: FoxG1, a member of the forkhead family, is a corepressor of the androgen receptor.

The following Foxg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42842	NM_012560.2 Latest version!	Rattus norvegicus forkhead box G1 (Foxg1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Foxg1 ( NM_012560.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036692.1 Rattus norvegicus forkhead box G1 (Foxg1), mRNA.

Price & Availability↑

CloneID	ORa42842
Clone ID Related Accession (Same CDS sequence)	NM_012560.2
Accession Version	NM_012560.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	forkhead box protein G1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07064224.1. On Nov 10, 2005 this sequence version replaced NM_012560.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: M87634.1 [ECO:0000345] ##Evidence-Data-END##

ATGCTGGACA TGGGAGATAG GAAAGAGGTG AAAATGATTC CCAAGTCCTC GTTCAGCATC 
AACAGCCTGG TCCCTGAGGC CGTCCAGAAC GACAACCACC ACGCGAGCCA CGGTCACCAC 
AACAGCCACC ACCCCCAGCA TCACCATCAT CATCACCACC ACCACCACCC GCCGCCGCCC 
GCGCCTCAGC CGCCGCCACC GCCGCCCCAG CAGCAGCAGC AGCCGCCCCC GGCCCCGCAG 
CCCCCGCAGG CGCGCGGCGC CCCAGCAGCG GACGACGACA AGGGCCCCCA GCCGCTTCTG 
CTCCCGCCGT CCGCCGCCCT GGACGGGGCC AAGGCTGACG CACTTGGAGC CAAAGGCGAG 
CCAGGCGGCG GGCCTGCGGA GCTGGCGCCC GTCGGGCCGG ACGAGAAGGA GAAGGGCGCG 
GGCGCTGGGG GGGAGGAGAA GAAGGGGGCG GGCGAGGGCG GCAAGGACGG GGAGGGGGGC 
AAGGAGGGCG ACAAGAAGAA CGGCAAGTAC GAGAAGCCGC CGTTCAGCTA CAACGCGCTC 
ATCATGATGG CCATCAGGCA GAGTCCCGAG AAGCGCCTGA CGCTCAACGG CATCTACGAG 
TTCATCATGA AGAACTTCCC TTACTACCGC GAGAACAAGC AGGGCTGGCA GAACTCCATC 
CGCCACAACC TGTCCCTCAA CAAGTGCTTC GTGAAGGTAC CGCGCCACTA CGACGACCCG 
GGCAAGGGCA ACTACTGGAT GCTGGACCCG TCGAGCGACG ACGTGTTCAT CGGCGGCACG 
ACCGGCAAGC TGCGGCGCCG CTCCACCACG TCTCGGGCCA AGCTAGCCTT TAAGCGCGGG 
GCACGGCTCA CCTCCACCGG CCTCACCTTC ATGGACCGCG CCGGCTCCCT CTACTGGCCC 
ATGTCGCCCT TCCTGTCCCT GCACCACCCT CGCGCCAGCA GCACTTTGAG TTACAACGGG 
ACCACGTCGG CCTACCCCAG CCACCCCATG CCCTACAGCT CCGTGTTGAC TCAAAACTCG 
CTGGGCAACA ACCACTCCTT CTCCACCGCC AACGGGCTGA GCGTGGACCG GCTGGTCAAC 
GGGGAGATCC CGTACGCCAC GCACCACCTC ACGGCCGCTG CGCTCGCCGC CTCCGTGCCC 
TGCGGCCTGT CGGTGCCCTG CTCCGGGACC TACTCCCTCA ACCCCTGCTC CGTCAACCTG 
CTCGCGGGCC AGACCAGTTA CTTTTTCCCC CACGTCCCGC ACCCGTCAAT GACTTCGCAG 
ACCAGCACGT CCATGAGCGC CCGGGCCGCG TCCTCCTCTA CGTCGCCGCA GGCCCCCTCG 
ACCCTGCCCT GTGAGTCTTT AAGACCCTCT TTGCCAAGTT TTACGACAGG ACTGTCCGGG 
GGACTGTCTG ATTATTTCAC ACATCAAAAT CAGGGGTCTT CTTCCAACCC TTTAATACAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036692.1
CDS	442..1884
Translation	MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPPPPAPQPPPPPPQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLPPSAALDGAKADALGAKGEPGGGPAELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH

Target ORF information:

RefSeq Version	NM_012560.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus forkhead box G1 (Foxg1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012560.2

ORF Insert Sequence:

ATGCTGGACA TGGGAGATAG GAAAGAGGTG AAAATGATTC CCAAGTCCTC GTTCAGCATC 
AACAGCCTGG TCCCTGAGGC CGTCCAGAAC GACAACCACC ACGCGAGCCA CGGTCACCAC 
AACAGCCACC ACCCCCAGCA TCACCATCAT CATCACCACC ACCACCACCC GCCGCCGCCC 
GCGCCTCAGC CGCCGCCACC GCCGCCCCAG CAGCAGCAGC AGCCGCCCCC GGCCCCGCAG 
CCCCCGCAGG CGCGCGGCGC CCCAGCAGCG GACGACGACA AGGGCCCCCA GCCGCTTCTG 
CTCCCGCCGT CCGCCGCCCT GGACGGGGCC AAGGCTGACG CACTTGGAGC CAAAGGCGAG 
CCAGGCGGCG GGCCTGCGGA GCTGGCGCCC GTCGGGCCGG ACGAGAAGGA GAAGGGCGCG 
GGCGCTGGGG GGGAGGAGAA GAAGGGGGCG GGCGAGGGCG GCAAGGACGG GGAGGGGGGC 
AAGGAGGGCG ACAAGAAGAA CGGCAAGTAC GAGAAGCCGC CGTTCAGCTA CAACGCGCTC 
ATCATGATGG CCATCAGGCA GAGTCCCGAG AAGCGCCTGA CGCTCAACGG CATCTACGAG 
TTCATCATGA AGAACTTCCC TTACTACCGC GAGAACAAGC AGGGCTGGCA GAACTCCATC 
CGCCACAACC TGTCCCTCAA CAAGTGCTTC GTGAAGGTAC CGCGCCACTA CGACGACCCG 
GGCAAGGGCA ACTACTGGAT GCTGGACCCG TCGAGCGACG ACGTGTTCAT CGGCGGCACG 
ACCGGCAAGC TGCGGCGCCG CTCCACCACG TCTCGGGCCA AGCTAGCCTT TAAGCGCGGG 
GCACGGCTCA CCTCCACCGG CCTCACCTTC ATGGACCGCG CCGGCTCCCT CTACTGGCCC 
ATGTCGCCCT TCCTGTCCCT GCACCACCCT CGCGCCAGCA GCACTTTGAG TTACAACGGG 
ACCACGTCGG CCTACCCCAG CCACCCCATG CCCTACAGCT CCGTGTTGAC TCAAAACTCG 
CTGGGCAACA ACCACTCCTT CTCCACCGCC AACGGGCTGA GCGTGGACCG GCTGGTCAAC 
GGGGAGATCC CGTACGCCAC GCACCACCTC ACGGCCGCTG CGCTCGCCGC CTCCGTGCCC 
TGCGGCCTGT CGGTGCCCTG CTCCGGGACC TACTCCCTCA ACCCCTGCTC CGTCAACCTG 
CTCGCGGGCC AGACCAGTTA CTTTTTCCCC CACGTCCCGC ACCCGTCAAT GACTTCGCAG 
ACCAGCACGT CCATGAGCGC CCGGGCCGCG TCCTCCTCTA CGTCGCCGCA GGCCCCCTCG 
ACCCTGCCCT GTGAGTCTTT AAGACCCTCT TTGCCAAGTT TTACGACAGG ACTGTCCGGG 
GGACTGTCTG ATTATTTCAC ACATCAAAAT CAGGGGTCTT CTTCCAACCC TTTAATACAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DNA-binding specificities of human transcription factors.
Cell152(1-2)327-39(2013 Jan)
Jolma A,Yan J,Whitington T,Toivonen J,Nitta KR,Rastas P,Morgunova E,Enge M,Taipale M,Wei G,Palin K,Vaquerizas JM,Vincentelli R,Luscombe NM,Hughes TR,Lemaire P,Ukkonen E,Kivioja T,Taipale J

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.
Neuron74(6)1045-58(2012 Jun)
Miyoshi G,Fishell G

Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain.
Developmental cell22(4)871-8(2012 Apr)
Yip DJ,Corcoran CP,Alvarez-Saavedra M,DeMaria A,Rennick S,Mears AJ,Rudnicki MA,Messier C,Picketts DJ

Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.
The Journal of biological chemistry287(18)14749-59(2012 Apr)
Dastidar SG,Narayanan S,Stifani S,D'Mello SR

Common increase of GATA-3 level in PC-12 cells by three teratogens causing autism spectrum disorders.
Neuroscience research64(2)162-9(2009 Jun)
Rout UK,Clausen P