Cp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cp
Entrez Gene ID	24268
Full Name	ceruloplasmin
Synonyms	CERP
General protein information	Preferred Names ceruloplasmin Names ceruloplasmin bilitranslocase ceruloplasmin (ferroxidase)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q24
Summary	copper-containing ferroxidase that promotes iron incorporation into transferrin; plays a role in iron metabolism and homeostatis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001270961.1	NP_001257890.1	ceruloplasmin isoform 2 precursor
XM_008760859.2	XP_008759081.1	ceruloplasmin isoform X1
NM_012532.2	NP_036664.2	ceruloplasmin isoform 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cp	NP_001257890.1
Gallus gallus (chicken)	CP	XP_001235149.2
	CP	XP_001109373.2
Homo sapiens (human)	CP	NP_000087.1
Bos taurus (cattle)	LOC514194	NP_001243485.1
Mus musculus (house mouse)	Cp	NP_001263177.1
Danio rerio (zebrafish)	cp	NP_571877.1
Xenopus tropicalis (tropical clawed frog)	cp	XP_002937375.1
Canis lupus familiaris (dog)	CP	XP_005634613.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of bilitranslocase and beta-glucuronidase in the vascular protection by hydroxytyrosol and its glucuronide metabolites in oxidative stress conditions.
Peyrol J, Meyer G, Obert P, Dangles O, Pech?re L, Amiot MJ, Riva C
The Journal of nutritional biochemistry518-15(2018 Jan)

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.
Chen TD, Rotival M, Chiu LY, Bagnati M, Ko JH, Srivastava PK, Petretto E, Pusey CD, Lai PC, Aitman TJ, Cook HT, Behmoaras J
Genetics206(2)1139-1151(2017 06)

Ironing out Ferroportin.
Drakesmith H, Nemeth E, Ganz T
Cell metabolism22(5)777-87(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results suggest that genetically determined Cp levels can alter susceptibility to Crescentic glomerulonephritis through macrophage function and propose a new role for Cp in early macrophage activation.
Title: Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.

Ferroportin 1 and CP colocalize in the rat brain.
Title: Ceruloplasmin is Involved in the Nigral Iron Accumulation of 6-OHDA-Lesioned Rats.

Data show there was no significant difference detected in hepatic and hippocampus iron levels in response to increased serum ceruloplasmin between control and copper-intoxicated rats.
Title: Hepatic and hippocampus iron status is not altered in response to increased serum ceruloplasmin and serum "free" copper in Wistar rat model for non-Wilsonian brain copper toxicosis.

FOX activity was present in rat cytosol, and was partly inhibited by anti-Heph antibody.
Title: Immunoreactive hephaestin and ferroxidase activity are present in the cytosolic fraction of rat enterocytes.

Liver copper loading increases metallation of the Cp protein, leading to increased production of the holo enzyme.
Title: Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake.

The following Cp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12362	NM_001270961.1 Latest version!	Rattus norvegicus ceruloplasmin (Cp), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa12370	NM_012532.2 Latest version!	Rattus norvegicus ceruloplasmin (Cp), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa12362	XM_008760859.2 Latest version!	Rattus norvegicus ceruloplasmin (ferroxidase) (Cp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cp ( NM_001270961.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257890.1 Rattus norvegicus ceruloplasmin (Cp), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12362
Clone ID Related Accession (Same CDS sequence)	NM_001270961.1 , XM_008760859.2
Accession Version	NM_001270961.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	ceruloplasmin isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC111684.6. Transcript Variant: This variant (2) lacks an exon and contains two alternate 3' exons compared to variant 1. The resulting protein (isoform 2), which is longer and has a distinct C-terminus compared to isoform 1, is a glycosylphosphatidylinositol-anchored form. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF202115.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGCATCGTC TCAGAGCTAC 
AGGATGACCT GGAACATACT CTATACACTG TTAATCAGCA TGACTACTTT ATTCCAAATA 
TCTACCAAGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257890.1
CDS	34..3288
Translation	MKFLLLSALLFLHSSLAWTREKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPNQASSQSYRMTWNILYTLLISMTTLFQISTKE

Target ORF information:

RefSeq Version	NM_001270961.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceruloplasmin (Cp), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270961.1

ORF Insert Sequence:

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGCATCGTC TCAGAGCTAC 
AGGATGACCT GGAACATACT CTATACACTG TTAATCAGCA TGACTACTTT ATTCCAAATA 
TCTACCAAGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cp ( NM_012532.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036664.2 Rattus norvegicus ceruloplasmin (Cp), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa12370
Clone ID Related Accession (Same CDS sequence)	NM_012532.2
Accession Version	NM_012532.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	ceruloplasmin isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC111684.6. On Aug 16, 2012 this sequence version replaced NM_012532.1. Transcript Variant: This variant (1) represents the longer transcript and encodes a secreted protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L33869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGAGACTAA GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036664.2
CDS	34..3213
Translation	MKFLLLSALLFLHSSLAWTREKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPNQETKSG

Target ORF information:

RefSeq Version	NM_012532.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceruloplasmin (Cp), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012532.2

ORF Insert Sequence:

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGAGACTAA GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cp ( XM_008760859.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759081.1 Rattus norvegicus ceruloplasmin (ferroxidase) (Cp), transcript variant X1, mRNA.

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CloneID	ORa12362
Clone ID Related Accession (Same CDS sequence)	NM_001270961.1 , XM_008760859.2
Accession Version	XM_008760859.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ceruloplasmin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760859.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGCATCGTC TCAGAGCTAC 
AGGATGACCT GGAACATACT CTATACACTG TTAATCAGCA TGACTACTTT ATTCCAAATA 
TCTACCAAGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759081.1
CDS	228..3482
Translation	MKFLLLSALLFLHSSLAWTREKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPNQASSQSYRMTWNILYTLLISMTTLFQISTKE

Target ORF information:

RefSeq Version	XM_008760859.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceruloplasmin (ferroxidase) (Cp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760859.2

ORF Insert Sequence:

ATGAAGTTTT TGCTGCTTAG TGCACTTTTA TTTTTGCATA GTTCCTTAGC TTGGACAAGA 
GAAAAGCATT ATTACATCGG AATTACTGAA GCAGTTTGGG ACTATGCTTC TGGCAGTGAA 
GAAAAGGAAC TTATTTCAGT TGACACGGAA CAGTCCAATT TCTATCTTCG AAATGGTCCA 
GATCGTATTG GAAGAAAGTA TAAGAAGGCC CTTTATTCTG AGTACACAGA TGGCACCTTT 
ACGAAGACTA TAGACAAACC AGCCTGGCTA GGGCTTTTAG GCCCTGTCAT CAAAGCTGAA 
GTTGGAGACA AAGTTTCTGT TCACGTAAAG AACTTTGCCT CTAGGCCCTA CACTTTTCAT 
GCTCATGGGG TAACTTACAC CAAGGCGAAC GAGGGGGCCA TCTACCCTGA CAACACCACT 
GATTTTCAAA GAGCCGATGA CAAACTGTTT CCTGGACAGC AGTATTTGTA CGTGCTGCGT 
GCCAATGAGC CAAGTCCTGG CGAGGGAGAC AGCAATTGTG TGACCAGGAT TTACCACTCT 
CATGTGGATG CTCCAAAAGA TATTGCATCA GGACTCATAG GACCGTTGAT ACTCTGTAAA 
AAAGGTTCTC TGCATAAGGA AAAAGAGGAA AATATTGACC AAGAATTCGT ACTGATGTTC 
TCTGTGGTGG ATGAAAATCT CAGCTGGTAT CTAGAAGATA ACATCAAAAC CTTCTGCTCG 
GAACCAGAGA AAGTCGATAA AGACAATGAA GACTTCCAGG AAAGCAACAG GATGTACTCT 
ATAAATGGAT ATACATTTGG AAGCCTCCCA GGGCTCTCGA TGTGTGCAGA AGACAGAGTG 
AAGTGGTACC TTTTTGGGAT GGGGAATGAA GTTGACGTGC ATTCAGCGCT CTTTCATGGT 
CAAGCCCTGA CCAGCAAGAA CTATCATACT GATATAATCA ACCTGTTCCC TGCCACTCTA 
ATTGATGTTT CTATGGTGGC CCAGAATCCT GGAGTCTGGA TGCTCAGTTG CCAGAACCTG 
AACCATCTGA AAGCTGGTTT GCAGGCCTTT TTCCAGGTTC GTGACTGCAA CAAGCCCTCA 
CCGGACGACG ATATCCAAGA CAGACATGTG AGACATTATT ACATCGCTGC CGAGGAGACC 
ATTTGGGACT ATGCTCCGTC TGGGACAGAC ACCTTCACTG GAGAGAACTT AACCAGTCTG 
GGAAGTGATT CAAGGGTATT TTTTGAGCAA GGTGCTACAA GAATTGGTGG CTCTTATAAA 
AAATTGGTTT ATCGTGAGTA CACAGATGAT TCCTTCACAA ACCGGAAGCA AAGAGGCCCT 
GATGAGGAAC ATCTTGGAAT CCTTGGTCCT GTCATTTGGG CAGAAGTAGG AGACATCATT 
AGAGTCACCT TTCATAACAA AGGACAATTT CCTCTCAGCA TTCAGCCAAT GGGGGTAAGA 
TTCACCAAGG AAAATGAGGG AACATACTAT GGCCCAGATG GCCGTTCCTC AAAGCAAGCC 
TCCCATGTGG CTCCCAAAGA AACCTTTACG TATGAATGGA CTGTCCCCAA AGAAATGGGA 
CCCACTTATG CAGATCCTGT GTGCCTATCT AAGATGTATT ATTCTGGAGT TGACCTCACC 
AAAGATATAT TTACTGGGCT TATTGGGCCA ATGAAAATAT GCAAGAAAGG CAGCTTACTT 
GCAGATGGGA GACAGAAAGA TGTAGACAAG GAGTTCTACT TGTTTGCAAC AGTGTTTGAT 
GAGAATGAGA GTTTACTCTT GGATGATAAT ATCAGAATGT TCACAACTGC ACCTGAGAAT 
GTGGACAAGG AAGATGAAGA CTTTCAGGAG TCCAACAAGA TGCACTCCAT GAATGGATTC 
ATGTATGGCA ATCTGCCTGG CCTCAATATG TGTCTAGGAG AATCCATCGT GTGGTATTTG 
TTCAGCGCTG GAAATGAGGC AGACGTGCAT GGGATATACT TTTCAGGAAA TACCTATCTG 
TCCAAAGGAG AAAGAAGAGA CACTGCAAAT CTATTTCCTC ATAAAAGTCT CACCCTTCTC 
ATGACACCTG ACACAGAAGG GTCTTTTGAT GTTGAGTGTC TTACAACAGA TCACTACACC 
GGTGGCATGA AGCAAAAGTA CACTGTGAAC CAGTGCAAGG GGCAGTTTGA AGATGTCACT 
CTCTACCAGG GAGAAAGGAC CTACTATATT GCAGCAGTGG AGGTGGAATG GGATTATTCA 
CCAAGCAGGG ACTGGGAAAT GGAGCTGCAC CATTTGCAAG AGCAAAATGT TTCAAATGCA 
TTTTTGGATA AGGAAGAGTT TTTCATAGGC TCAAAGTACA AGAAGGTTGT GTATCGAGAG 
TTTACTGACA GCACATTCAG AGAACAGGTG AAGAGAAGAG CTGAAGAGGA GCACTTGGGC 
ATCCTCGGTC CACTGATTCA TGCAGATGTT GGAGACAAAG TTAAAGTTGT CTTTAAAAAT 
ATGGCAAGCA GGCCATATTC AATACATGCC CACGGAGTGA AAACAAAGAG TTCTACAGTT 
GCTCCAACGT TACCAGGTGA AGTTCGCACT TATATATGGC AAATTCCAGA AAGATCAGGT 
GCTGGAACGG AGGATTCACC TTGTATCCCA TGGGCTTATT ACTCAACCGT GGATCGAGTT 
AAGGATCTCT ATAGTGGGCT AATAGGCCCA TTGATTGTTT GTCGGAAATC TTATGTGAAA 
GTATTCAATC CTAAAAAGAA AATGGAGTTT TCCCTTTTGT TTCTAGTATT TGATGAGAAT 
GAATCTTGGT ACTTAGATGA TAACATCAAT ACATACTCTG ATCACCCTGA GAAAGTAAAC 
AAAGACAACG AGGAATTCAT AGAAAGCAAT AAAATGCATG CTATCAATGG GAAAATGTTC 
GGAAACCTAC AAGGTCTCAC GATGCACGTG GGAGACGAGG TCAACTGGTA TGTGATGGCT 
ATGGGCAATG AAATAGACCT GCACACTGTA CACTTCCACG GCCACAGCTT CCAATACAAG 
CACAGGGGAA TTCATAGTTC TGATGTCTTT GACCTTTTTC CTGGAACATA CCAAACCCTA 
GAGATGTTTC CCCAAACGCC TGGAACCTGG TTACTCCACT GCCATGTGAC TGACCATATT 
CATGCGGGGA TGGTAACTAC CTACACTGTT TTACCAAATC AAGCATCGTC TCAGAGCTAC 
AGGATGACCT GGAACATACT CTATACACTG TTAATCAGCA TGACTACTTT ATTCCAAATA 
TCTACCAAGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of bilitranslocase and beta-glucuronidase in the vascular protection by hydroxytyrosol and its glucuronide metabolites in oxidative stress conditions.
The Journal of nutritional biochemistry518-15(2018 Jan)
Peyrol J,Meyer G,Obert P,Dangles O,Pech?re L,Amiot MJ,Riva C

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.
Genetics206(2)1139-1151(2017 06)
Chen TD,Rotival M,Chiu LY,Bagnati M,Ko JH,Srivastava PK,Petretto E,Pusey CD,Lai PC,Aitman TJ,Cook HT,Behmoaras J

Ironing out Ferroportin.
Cell metabolism22(5)777-87(2015 Nov)
Drakesmith H,Nemeth E,Ganz T

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Cp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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