Cebpb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cebpb
Entrez Gene ID	24253
Full Name	CCAAT/enhancer binding protein beta
Synonyms	Il6dbp,NF-IL6,TCF5
General protein information	Preferred Names CCAAT/enhancer binding protein beta Names CCAAT/enhancer-binding protein beta C/EBP beta CCAAT/enhancer binding protein (C/EBP), beta IL-6DBP SF-B interleukin-6-dependent-binding protein nuclear factor-IL6 silencer factor B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42
Summary	This intronless gene encodes a member of the transcription factor family whose members contain a basic leucine-zipper domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. The encoded protein plays important roles in several cellular processes and in various diseases, including regulating cell proliferation, differentiation, apoptosis and neuroinflammation, and being involved in brain injury and inflammatory progression. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with different cellular localizations and distinct biological functions. [provided by RefSeq, Sep 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001301720.1	NP_001288649.1	CCAAT/enhancer-binding protein beta isoform LIP
NM_024125.5	NP_077039.3	CCAAT/enhancer-binding protein beta isoform LAP1
NM_001301715.1	NP_001288644.1	CCAAT/enhancer-binding protein beta isoform LAP2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cebpb	NP_077039.3
Canis lupus familiaris (dog)	CEBPB	XP_005635227.1
Pan troglodytes (chimpanzee)	CEBPB	XP_003953819.1
Mus musculus (house mouse)	Cebpb	NP_034013.1
Gallus gallus (chicken)	CEBPB	NP_990584.1
	LOC713191	XP_001102454.2
Homo sapiens (human)	CEBPB	NP_005185.2
Xenopus tropicalis (tropical clawed frog)	cebpb	NP_001030293.1

Gene Ontology
Bibliography

Related articles in PubMed

Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells.
Masuda M, Miyazaki-Anzai S, Keenan AL, Shiozaki Y, Okamura K, Chick WS, Williams K, Zhao X, Rahman SM, Tintut Y, Adams CM, Miyazaki M
JCI insight1(18)e88646(2016 Nov)

The transcription factor CCAAT enhancer-binding protein ? protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms.
Pe?a-Altamira E, Polazzi E, Moretto E, Lauriola M, Monti B
The European journal of neuroscience39(2)176-85(2014 Jan)

Expression, hormonal regulation, and subcellular localization of CCAAT/enhancer-binding protein-beta in rat and human thyrocytes.
Pom?rance M, Mockey M, Young J, Quillard J, Blondeau JP
Thyroid : official journal of the American Thyroid Association15(3)197-204(2005 Mar)

Translational control of C/EBPalpha and C/EBPbeta isoform expression.
Calkhoven CF, M?ller C, Leutz A
Genes & development14(15)1920-32(2000 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The present study indicates a requirement for C/EBPbeta in the insulin-mediated induction of SREBP-1c mRNA expression in rodent liver. Coupled with previous data showing that this induction requires LXRalpha, our data reported herein indicate a requirement for both transcription factors.
Title: Insulin induction of SREBP-1c in rodent liver requires LXR?-C/EBP? complex.

C/EBP beta acts as a potent pro-inflammatory mediator by inducing the TNF-alpha gene at the transcription and protein levels via the ERK1/2 and p38 pathways in nucleus pulposus.
Title: CCAAT/enhancer binding protein ? regulates the expression of tumor necrosis factor-? in the nucleus pulposus cells.

Catalase promoter region (-185 to +52) that contains binding sites for C/EBP-beta showed an augmentation in the methylation level along with a change in methylation pattern of CpG islands in response to PTU treatment
Title: Neonatal Persistent Exposure to 6-Propyl-2-thiouracil, a Thyroid-Disrupting Chemical, Differentially Modulates Expression of Hepatic Catalase and C/EBP-? in Adult Rats.

Lipopolysaccharide elicits depressive-like behaviour in both sexes, inflammation may shape phenotype via hypothalamus in a sex-dependant manner, C/EBPbeta variants and glucocorticoid receptor signaling may be inflammatory mediators of these processes
Title: The contribution of hypothalamic neuroendocrine, neuroplastic and neuroinflammatory processes to lipopolysaccharide-induced depressive-like behaviour in female and male rats: Involvement of glucocorticoid receptor and C/EBP-?.

results revealed a robust anti-hypertrophic and anti-remodeling effect of ALA, which is mediated by inhibition of C/EBPbeta activation.
Title: Alpha-lipoic acid attenuates cardiac hypertrophy via inhibition of C/EBP? activation.

The following Cebpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cebpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13319	NM_024125.5 Latest version!	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
ORa42873	NM_001301715.1 Latest version!	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
ORa42874	NM_001301720.1 Latest version!	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cebpb ( NM_024125.5 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077039.3 Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa13319
Clone ID Related Accession (Same CDS sequence)	NM_024125.5
Accession Version	NM_024125.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	CCAAT/enhancer-binding protein beta isoform LAP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117059.9 and BC129071.1. On Sep 11, 2014 this sequence version replaced NM_024125.4. Transcript Variant: This variant (1) encodes multiple isoforms through the use of alternative translation initiation codons. The isoform (LAP1, also known as LAP* or p38) represented in this RefSeq results from translation initiation at the 5' most AUG start codon and is the longest isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC129071.1 [ECO:0000345] ##Evidence-Data-END##

ATGCACCGCC TGCTGGCCTG GGACGCAGCA TGCCTCCCGC CGCCGCCCGC CGCCTTTAGA 
CCCATGGAAG TGGCCAACTT CTACTACGAG CCCGACTGCC TGGCCTACGG GGCCAAGGCG 
GCCCGCGCCG CGCCGCGCGC CCCCGCCGCC GAGCCGGCCA TCGGCGAGCA CGAGCGCGCC 
ATCGACTTCA GCCCCTACCT GGAGCCGCTC GCGCCCGCCG CCGCGGACTT CGCCGCGCCC 
GCGCCCGCGC ACCACGACTT CCTTTCCGAC CTCTTCGCCG ACGACTACGG CGCCAAGCCG 
AGCAAGAAGC CGTCCGACTA CGGTTACGTG AGCCTCGGCC GCGCGGGCGC CAAGGCCGCA 
CCGCCCGCCT GCTTCCCGCC GCCGCCTCCC GCCGCACTCA AGGCCGAGCC GGGCTTCGAA 
CCCGCGGACT GCAAGCGCGC GGACGACGCG CCCGCCATGG CGGCCGGCTT CCCGTTCGCC 
CTGCGCGCCT ACCTGGGCTA CCAGGCGACG CCGAGCGGCA GCAGCGGCAG CCTGTCCACG 
TCGTCGTCGT CCAGCCCGCC CGGGACGCCG AGCCCCGCCG ACGCCAAGGC CGCGCCCGCC 
GCCTGCTTCG CGGGGCCGCC GGCCGCGCCC GCCAAGGCCA AGGCCAAGAA GGCGGTGGAC 
AAGCTGAGCG ACGAGTACAA GATGCGGCGC GAGCGCAACA ACATCGCGGT GCGCAAGAGC 
CGCGACAAGG CCAAGATGCG CAACCTGGAG ACGCAGCACA AGGTGCTGGA GCTGACGGCG 
GAGAACGAGC GGCTGCAGAA GAAGGTGGAG CAGCTGTCGC GAGAGCTCAG CACGCTGCGG 
AACTTGTTCA AGCAGCTGCC CGAGCCGCTG CTGGCCTCGG CGGGTCACTG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077039.3
CDS	54..947
Translation	MHRLLAWDAACLPPPPAAFRPMEVANFYYEPDCLAYGAKAARAAPRAPAAEPAIGEHERAIDFSPYLEPLAPAAADFAAPAPAHHDFLSDLFADDYGAKPSKKPSDYGYVSLGRAGAKAAPPACFPPPPPAALKAEPGFEPADCKRADDAPAMAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKAAPAACFAGPPAAPAKAKAKKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASAGHC

Target ORF information:

RefSeq Version	NM_024125.5
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024125.5

ORF Insert Sequence:

ATGCACCGCC TGCTGGCCTG GGACGCAGCA TGCCTCCCGC CGCCGCCCGC CGCCTTTAGA 
CCCATGGAAG TGGCCAACTT CTACTACGAG CCCGACTGCC TGGCCTACGG GGCCAAGGCG 
GCCCGCGCCG CGCCGCGCGC CCCCGCCGCC GAGCCGGCCA TCGGCGAGCA CGAGCGCGCC 
ATCGACTTCA GCCCCTACCT GGAGCCGCTC GCGCCCGCCG CCGCGGACTT CGCCGCGCCC 
GCGCCCGCGC ACCACGACTT CCTTTCCGAC CTCTTCGCCG ACGACTACGG CGCCAAGCCG 
AGCAAGAAGC CGTCCGACTA CGGTTACGTG AGCCTCGGCC GCGCGGGCGC CAAGGCCGCA 
CCGCCCGCCT GCTTCCCGCC GCCGCCTCCC GCCGCACTCA AGGCCGAGCC GGGCTTCGAA 
CCCGCGGACT GCAAGCGCGC GGACGACGCG CCCGCCATGG CGGCCGGCTT CCCGTTCGCC 
CTGCGCGCCT ACCTGGGCTA CCAGGCGACG CCGAGCGGCA GCAGCGGCAG CCTGTCCACG 
TCGTCGTCGT CCAGCCCGCC CGGGACGCCG AGCCCCGCCG ACGCCAAGGC CGCGCCCGCC 
GCCTGCTTCG CGGGGCCGCC GGCCGCGCCC GCCAAGGCCA AGGCCAAGAA GGCGGTGGAC 
AAGCTGAGCG ACGAGTACAA GATGCGGCGC GAGCGCAACA ACATCGCGGT GCGCAAGAGC 
CGCGACAAGG CCAAGATGCG CAACCTGGAG ACGCAGCACA AGGTGCTGGA GCTGACGGCG 
GAGAACGAGC GGCTGCAGAA GAAGGTGGAG CAGCTGTCGC GAGAGCTCAG CACGCTGCGG 
AACTTGTTCA AGCAGCTGCC CGAGCCGCTG CTGGCCTCGG CGGGTCACTG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cebpb ( NM_001301715.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001288644.1 Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa42873
Clone ID Related Accession (Same CDS sequence)	NM_001301715.1
Accession Version	NM_001301715.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	CCAAT/enhancer-binding protein beta isoform LAP2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117059.9 and BC129071.1. Transcript Variant: This variant (1) encodes multiple isoforms through the use of alternative translation initiation codons. The isoform [LAP2, also known as LAP (liver activating protein), p34 or CRP2 (c/EBP-related protein 2)] represented in this RefSeq results from translation initiation at a downstream AUG start codon. Isoform LAP2 has a shorter N-terminus, compared to isoform LAP1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC129071.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:1934061) regulatory uORF :: PMID: 10921906 ##RefSeq-Attributes-END##

ATGGAAGTGG CCAACTTCTA CTACGAGCCC GACTGCCTGG CCTACGGGGC CAAGGCGGCC 
CGCGCCGCGC CGCGCGCCCC CGCCGCCGAG CCGGCCATCG GCGAGCACGA GCGCGCCATC 
GACTTCAGCC CCTACCTGGA GCCGCTCGCG CCCGCCGCCG CGGACTTCGC CGCGCCCGCG 
CCCGCGCACC ACGACTTCCT TTCCGACCTC TTCGCCGACG ACTACGGCGC CAAGCCGAGC 
AAGAAGCCGT CCGACTACGG TTACGTGAGC CTCGGCCGCG CGGGCGCCAA GGCCGCACCG 
CCCGCCTGCT TCCCGCCGCC GCCTCCCGCC GCACTCAAGG CCGAGCCGGG CTTCGAACCC 
GCGGACTGCA AGCGCGCGGA CGACGCGCCC GCCATGGCGG CCGGCTTCCC GTTCGCCCTG 
CGCGCCTACC TGGGCTACCA GGCGACGCCG AGCGGCAGCA GCGGCAGCCT GTCCACGTCG 
TCGTCGTCCA GCCCGCCCGG GACGCCGAGC CCCGCCGACG CCAAGGCCGC GCCCGCCGCC 
TGCTTCGCGG GGCCGCCGGC CGCGCCCGCC AAGGCCAAGG CCAAGAAGGC GGTGGACAAG 
CTGAGCGACG AGTACAAGAT GCGGCGCGAG CGCAACAACA TCGCGGTGCG CAAGAGCCGC 
GACAAGGCCA AGATGCGCAA CCTGGAGACG CAGCACAAGG TGCTGGAGCT GACGGCGGAG 
AACGAGCGGC TGCAGAAGAA GGTGGAGCAG CTGTCGCGAG AGCTCAGCAC GCTGCGGAAC 
TTGTTCAAGC AGCTGCCCGA GCCGCTGCTG GCCTCGGCGG GTCACTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288644.1
CDS	117..947
Translation	MEVANFYYEPDCLAYGAKAARAAPRAPAAEPAIGEHERAIDFSPYLEPLAPAAADFAAPAPAHHDFLSDLFADDYGAKPSKKPSDYGYVSLGRAGAKAAPPACFPPPPPAALKAEPGFEPADCKRADDAPAMAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKAAPAACFAGPPAAPAKAKAKKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASAGHC

Target ORF information:

RefSeq Version	NM_001301715.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301715.1

ORF Insert Sequence:

ATGGAAGTGG CCAACTTCTA CTACGAGCCC GACTGCCTGG CCTACGGGGC CAAGGCGGCC 
CGCGCCGCGC CGCGCGCCCC CGCCGCCGAG CCGGCCATCG GCGAGCACGA GCGCGCCATC 
GACTTCAGCC CCTACCTGGA GCCGCTCGCG CCCGCCGCCG CGGACTTCGC CGCGCCCGCG 
CCCGCGCACC ACGACTTCCT TTCCGACCTC TTCGCCGACG ACTACGGCGC CAAGCCGAGC 
AAGAAGCCGT CCGACTACGG TTACGTGAGC CTCGGCCGCG CGGGCGCCAA GGCCGCACCG 
CCCGCCTGCT TCCCGCCGCC GCCTCCCGCC GCACTCAAGG CCGAGCCGGG CTTCGAACCC 
GCGGACTGCA AGCGCGCGGA CGACGCGCCC GCCATGGCGG CCGGCTTCCC GTTCGCCCTG 
CGCGCCTACC TGGGCTACCA GGCGACGCCG AGCGGCAGCA GCGGCAGCCT GTCCACGTCG 
TCGTCGTCCA GCCCGCCCGG GACGCCGAGC CCCGCCGACG CCAAGGCCGC GCCCGCCGCC 
TGCTTCGCGG GGCCGCCGGC CGCGCCCGCC AAGGCCAAGG CCAAGAAGGC GGTGGACAAG 
CTGAGCGACG AGTACAAGAT GCGGCGCGAG CGCAACAACA TCGCGGTGCG CAAGAGCCGC 
GACAAGGCCA AGATGCGCAA CCTGGAGACG CAGCACAAGG TGCTGGAGCT GACGGCGGAG 
AACGAGCGGC TGCAGAAGAA GGTGGAGCAG CTGTCGCGAG AGCTCAGCAC GCTGCGGAAC 
TTGTTCAAGC AGCTGCCCGA GCCGCTGCTG GCCTCGGCGG GTCACTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cebpb ( NM_001301720.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001288649.1 Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa42874
Clone ID Related Accession (Same CDS sequence)	NM_001301720.1
Accession Version	NM_001301720.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	CCAAT/enhancer-binding protein beta isoform LIP
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117059.9 and BC129071.1. Transcript Variant: This variant (1) encodes multiple isoforms through the use of alternative translation initiation codons. The isoform [LIP (liver inhibitory protein) or p20] represented in this RefSeq results from translation initiation at a downstream AUG start codon. Isoform LIP has a shorter N-terminus, compared to isoform LAP1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC129071.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:1934061) regulatory uORF :: PMID: 10921906 ##RefSeq-Attributes-END##

ATGGCGGCCG GCTTCCCGTT CGCCCTGCGC GCCTACCTGG GCTACCAGGC GACGCCGAGC 
GGCAGCAGCG GCAGCCTGTC CACGTCGTCG TCGTCCAGCC CGCCCGGGAC GCCGAGCCCC 
GCCGACGCCA AGGCCGCGCC CGCCGCCTGC TTCGCGGGGC CGCCGGCCGC GCCCGCCAAG 
GCCAAGGCCA AGAAGGCGGT GGACAAGCTG AGCGACGAGT ACAAGATGCG GCGCGAGCGC 
AACAACATCG CGGTGCGCAA GAGCCGCGAC AAGGCCAAGA TGCGCAACCT GGAGACGCAG 
CACAAGGTGC TGGAGCTGAC GGCGGAGAAC GAGCGGCTGC AGAAGAAGGT GGAGCAGCTG 
TCGCGAGAGC TCAGCACGCT GCGGAACTTG TTCAAGCAGC TGCCCGAGCC GCTGCTGGCC 
TCGGCGGGTC ACTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288649.1
CDS	510..947
Translation	MAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKAAPAACFAGPPAAPAKAKAKKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASAGHC

Target ORF information:

RefSeq Version	NM_001301720.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CCAAT/enhancer binding protein beta (Cebpb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301720.1

ORF Insert Sequence:

ATGGCGGCCG GCTTCCCGTT CGCCCTGCGC GCCTACCTGG GCTACCAGGC GACGCCGAGC 
GGCAGCAGCG GCAGCCTGTC CACGTCGTCG TCGTCCAGCC CGCCCGGGAC GCCGAGCCCC 
GCCGACGCCA AGGCCGCGCC CGCCGCCTGC TTCGCGGGGC CGCCGGCCGC GCCCGCCAAG 
GCCAAGGCCA AGAAGGCGGT GGACAAGCTG AGCGACGAGT ACAAGATGCG GCGCGAGCGC 
AACAACATCG CGGTGCGCAA GAGCCGCGAC AAGGCCAAGA TGCGCAACCT GGAGACGCAG 
CACAAGGTGC TGGAGCTGAC GGCGGAGAAC GAGCGGCTGC AGAAGAAGGT GGAGCAGCTG 
TCGCGAGAGC TCAGCACGCT GCGGAACTTG TTCAAGCAGC TGCCCGAGCC GCTGCTGGCC 
TCGGCGGGTC ACTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells.
JCI insight1(18)e88646(2016 Nov)
Masuda M,Miyazaki-Anzai S,Keenan AL,Shiozaki Y,Okamura K,Chick WS,Williams K,Zhao X,Rahman SM,Tintut Y,Adams CM,Miyazaki M

The transcription factor CCAAT enhancer-binding protein ? protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms.
The European journal of neuroscience39(2)176-85(2014 Jan)
Pe?a-Altamira E,Polazzi E,Moretto E,Lauriola M,Monti B

Expression, hormonal regulation, and subcellular localization of CCAAT/enhancer-binding protein-beta in rat and human thyrocytes.
Thyroid : official journal of the American Thyroid Association15(3)197-204(2005 Mar)
Pom?rance M,Mockey M,Young J,Quillard J,Blondeau JP

Translational control of C/EBPalpha and C/EBPbeta isoform expression.
Genes & development14(15)1920-32(2000 Aug)
Calkhoven CF,M?ller C,Leutz A

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Cebpb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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