Adcyap1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adcyap1
Entrez Gene ID	24166
Full Name	adenylate cyclase activating polypeptide 1
Synonyms	Pacap
General protein information	Preferred Names adenylate cyclase activating polypeptide 1 Names pituitary adenylate cyclase-activating polypeptide adenylate cyclase activating polypeptide 1 (pituitary) pituitary adenylate cyclase activating polypeptide 1 pituitary adenylate cyclase-activating polypeptide precursor (Pacap)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q38
Summary	regulatory protein that stimulates cell proliferation, induces differentiation, modulates neurotransmitter release, vasodilation, bronchodilation, and hormone release, and suppresses inflammatory responses [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006245672.3	XP_006245734.1	pituitary adenylate cyclase-activating polypeptide isoform X1
XM_006245674.3	XP_006245736.1	pituitary adenylate cyclase-activating polypeptide isoform X1
NM_016989.2	NP_058685.1	pituitary adenylate cyclase-activating polypeptide precursor
XM_008767418.2	XP_008765640.1	pituitary adenylate cyclase-activating polypeptide isoform X1
XM_006245673.3	XP_006245735.1	pituitary adenylate cyclase-activating polypeptide isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADCYAP1	NP_001093203.1
Xenopus tropicalis (tropical clawed frog)	adcyap1	NP_001096425.1
Rattus norvegicus (Norway rat)	Adcyap1	NP_058685.1
Gallus gallus (chicken)	ADCYAP1	NP_001001291.2
Mus musculus (house mouse)	Adcyap1	NP_033755.1
Pan troglodytes (chimpanzee)	ADCYAP1	NP_001181872.1
Canis lupus familiaris (dog)	ADCYAP1	XP_849191.2
Bos taurus (cattle)	ADCYAP1	NP_001040020.1

Gene Ontology
Bibliography

Related articles in PubMed

Altered Gene Expression of RNF34 and PACAP Possibly Involved in Mechanism of Exercise-Induced Analgesia for Neuropathic Pain in Rats.
Yamaoka S, Oshima Y, Horiuchi H, Morino T, Hino M, Miura H, Ogata T
International journal of molecular sciences18(9)(2017 Sep)

Chronic changes in pituitary adenylate cyclase-activating polypeptide and related receptors in response to repeated chemical dural stimulation in rats.
Han X, Ran Y, Su M, Liu Y, Tang W, Dong Z, Yu S
Molecular pain131744806917720361(2017 Jan-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that chronic pain-induced pituitary adenylate cyclase-activating polypeptide neuroplasticity and signaling in spinoparabrachioamygdaloid projections have an impact on central nucleus of the amygdala stress- and nociception-associated maladaptive responses, which can be ameliorated upon receptor antagonism even during injury progression.
Title: Parabrachial Pituitary Adenylate Cyclase-Activating Polypeptide Activation of Amygdala Endosomal Extracellular Signal-Regulated Kinase Signaling Regulates the Emotional Component of Pain.

Our data are the first to shed light on PACAP as a secretagogue regulating a sustained production of morphogens, which in turn could enable PACAP to serve as a mitogen for retinal cells, to induce ganglion cell differentiation, and to contribute to RPE development.
Title: Pituitary Adenylate Cyclase-Activating Peptide (PACAP), a Novel Secretagogue, Regulates Secreted Morphogens in Newborn Rat Retina.

The results of this study showed that hypothalamic PACAP mRNA expression decreased during development in both male and female rats.
Title: Developmental changes in the hypothalamic mRNA expression levels of PACAP and its receptor PAC1 and their sensitivity to fasting in male and female rats.

Observations suggest that the hypothalamic peptides pituitary adenylate cyclase-activating polypeptide, kisspeptin, and gonadotropin-releasing hormone are interrelated and maintain placental functions.
Title: Expression and Regulation of Pituitary Adenylate Cyclase-Activating Polypeptide in Rat Placental Cells.

These results strongly support the concept that while cAMP signaling can accelerate the degradation of Pacap mRNA, it can also synergistically enhance Ca(2+) signaling-induced transcriptional activation of Pacap
Title: Balance between cAMP and Ca(2+) signals regulates expression levels of pituitary adenylate cyclase-activating polypeptide gene in neurons.

The following Adcyap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adcyap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12713	NM_016989.2 Latest version!	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12713	XM_006245672.3 Latest version!	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12713	XM_008767418.2 Latest version!	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12713	XM_006245674.3 Latest version!	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12713	XM_006245673.3 Latest version!	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adcyap1 ( NM_016989.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058685.1 Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), mRNA.

Price & Availability↑

CloneID	ORa12713
Clone ID Related Accession (Same CDS sequence)	XM_006245672.3 , XM_006245674.3 , NM_016989.2 , XM_008767418.2 , XM_006245673.3
Accession Version	NM_016989.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	pituitary adenylate cyclase-activating polypeptide precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB786482.1, M63006.1 and BG664825.1. On Feb 23, 2007 this sequence version replaced NM_016989.1. Sequence Note: The sequence M63006.1 is from a chimeric clone. Only the adenylate cyclase activating polypeptide 1 sequence region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058685.1
CDS	297..824
Translation	MTMCSGARLALLVYGIIMHNSVSCSPAAGLSFPGIRPEEEAYDQDGNPLQDFYDWDPPGAGSPASALRDAYALYYPADRRDVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL

Target ORF information:

RefSeq Version	NM_016989.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016989.2

ORF Insert Sequence:

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcyap1 ( XM_006245672.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245734.1 Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12713
Clone ID Related Accession (Same CDS sequence)	XM_006245672.3 , XM_006245674.3 , NM_016989.2 , XM_008767418.2 , XM_006245673.3
Accession Version	XM_006245672.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pituitary adenylate cyclase-activating polypeptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245672.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245734.1
CDS	273..800
Translation	MTMCSGARLALLVYGIIMHNSVSCSPAAGLSFPGIRPEEEAYDQDGNPLQDFYDWDPPGAGSPASALRDAYALYYPADRRDVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL

Target ORF information:

RefSeq Version	XM_006245672.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245672.3

ORF Insert Sequence:

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcyap1 ( XM_006245674.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245736.1 Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa12713
Clone ID Related Accession (Same CDS sequence)	XM_006245672.3 , XM_006245674.3 , NM_016989.2 , XM_008767418.2 , XM_006245673.3
Accession Version	XM_006245674.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pituitary adenylate cyclase-activating polypeptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245674.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245736.1
CDS	1213..1740
Translation	MTMCSGARLALLVYGIIMHNSVSCSPAAGLSFPGIRPEEEAYDQDGNPLQDFYDWDPPGAGSPASALRDAYALYYPADRRDVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL

Target ORF information:

RefSeq Version	XM_006245674.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245674.3

ORF Insert Sequence:

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcyap1 ( XM_008767418.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765640.1 Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa12713
Clone ID Related Accession (Same CDS sequence)	XM_006245672.3 , XM_006245674.3 , NM_016989.2 , XM_008767418.2 , XM_006245673.3
Accession Version	XM_008767418.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pituitary adenylate cyclase-activating polypeptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767418.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765640.1
CDS	227..754
Translation	MTMCSGARLALLVYGIIMHNSVSCSPAAGLSFPGIRPEEEAYDQDGNPLQDFYDWDPPGAGSPASALRDAYALYYPADRRDVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL

Target ORF information:

RefSeq Version	XM_008767418.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767418.2

ORF Insert Sequence:

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcyap1 ( XM_006245673.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245735.1 Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12713
Clone ID Related Accession (Same CDS sequence)	XM_006245672.3 , XM_006245674.3 , NM_016989.2 , XM_008767418.2 , XM_006245673.3
Accession Version	XM_006245673.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	pituitary adenylate cyclase-activating polypeptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245673.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245735.1
CDS	1259..1786
Translation	MTMCSGARLALLVYGIIMHNSVSCSPAAGLSFPGIRPEEEAYDQDGNPLQDFYDWDPPGAGSPASALRDAYALYYPADRRDVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL

Target ORF information:

RefSeq Version	XM_006245673.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenylate cyclase activating polypeptide 1 (Adcyap1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245673.3

ORF Insert Sequence:

ATGACCATGT GTAGCGGAGC AAGGTTGGCC CTGTTGGTCT ACGGGATAAT AATGCATAAC 
AGCGTCTCCT GTTCACCTGC CGCCGGACTC AGCTTCCCTG GGATCAGACC AGAAGAAGAG 
GCTTACGATC AGGACGGAAA CCCGCTGCAA GACTTCTACG ACTGGGACCC TCCGGGCGCA 
GGGAGCCCCG CCTCCGCGCT GCGTGACGCC TACGCCCTTT ACTACCCAGC CGACAGGAGA 
GATGTCGCCC ACGAAATCCT TAACGAAGCC TACCGCAAAG TCTTGGACCA GCTGTCCGCC 
AGGAAGTACC TGCAGTCCAT GGTGGCCAGG GGCATGGGCG AGAACCTCGC CGCCGCCGCG 
GTGGACGACC GGGCACCCCT TACCAAACGC CACTCGGACG GCATCTTCAC AGACAGCTAT 
AGCCGCTACC GAAAACAAAT GGCTGTCAAG AAATACTTGG CGGCCGTGCT AGGGAAAAGG 
TATAAACAGA GGGTTAAAAA CAAAGGACGC CGAATAGCGT ACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered Gene Expression of RNF34 and PACAP Possibly Involved in Mechanism of Exercise-Induced Analgesia for Neuropathic Pain in Rats.
International journal of molecular sciences18(9)(2017 Sep)
Yamaoka S,Oshima Y,Horiuchi H,Morino T,Hino M,Miura H,Ogata T

Chronic changes in pituitary adenylate cyclase-activating polypeptide and related receptors in response to repeated chemical dural stimulation in rats.
Molecular pain131744806917720361(2017 Jan-Dec)
Han X,Ran Y,Su M,Liu Y,Tang W,Dong Z,Yu S

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Adcyap1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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