Podxl cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Podxl
Entrez Gene ID	192181
Full Name	podocalyxin-like
Synonyms	PC,PCLP-1,podocalyxin
General protein information	Preferred Names podocalyxin-like Names podocalyxin podocalyxin-like protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q22
Summary	inhibits cell-cell adhesion; may play a role in maintaining filtration in the glomerular epithelium [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008762758.2	XP_008760980.1	podocalyxin isoform X1
XM_017592427.1	XP_017447916.1	podocalyxin isoform X2
NM_138848.1	NP_620203.1	podocalyxin precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Podxl	NP_038751.2
Rattus norvegicus (Norway rat)	Podxl	NP_620203.1

Gene Ontology
Bibliography

Related articles in PubMed

The effect of connective tissue growth factor on renal fibrosis and podocyte injury in hypertensive rats.
Lu W, Liu S, Zhao Z, Liu Y, Li T
Renal failure36(9)1420-7(2014 Oct)

Expression of caveolin-1 and podocalyxin in rat lungs challenged with 2-kDa macrophage-activating lipopeptide and Flt3L.
Tschernig T, Pabst R, Kasper M, El-Hadi M, Singh B
Cell and tissue research356(1)207-16(2014 Apr)

Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7.
Hsu YH, Lin WL, Hou YT, Pu YS, Shun CT, Chen CL, Wu YY, Chen JY, Chen TH, Jou TS
The American journal of pathology176(6)3050-61(2010 Jun)

Ubiquitous yet distinct expression of podocalyxin on vascular surfaces in normal and tumor tissues in the rat.
Testa JE, Chrastina A, Li Y, Oh P, Schnitzer JE
Journal of vascular research46(4)311-24(2009)

Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation.
Kobayashi T, Notoya M, Shinosaki T, Kurihara H
Nephron. Experimental nephrology113(3)e89-96(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both the overexpression of CTGF and the loss of podocalyxin reflect renal damage in spontaneously hypertensive rats. CTGF and PCX may be involved in the mechanisms of podocyte injury and apoptosis induced by hypertension
Title: The effect of connective tissue growth factor on renal fibrosis and podocyte injury in hypertensive rats.

The immunohistochemical expression of caveolin-1 and podocalyxin in lungs from rats challenged with a 2-kDa macrophage-activating lipopeptide (MALP-2) and Flt3L, was examined.
Title: Expression of caveolin-1 and podocalyxin in rat lungs challenged with 2-kDa macrophage-activating lipopeptide and Flt3L.

Report ubiquitous yet distinct expression of podocalyxin on vascular surfaces in normal and tumor tissues in the rat.
Title: Ubiquitous yet distinct expression of podocalyxin on vascular surfaces in normal and tumor tissues in the rat.

cortactin mediates interaction between podocalyxin and actin filaments in podocytes and that alteration of this interaction may play a role in the process of morphological change of podocytes.
Title: Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation.

Podocalyxin might be associated with the malignant progression of astrocytic tumors, and be a useful prognostic marker for astrocytic tumors.
Title: Podocalyxin expression in malignant astrocytic tumors.

The following Podxl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Podxl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01723	NM_138848.1 Latest version!	Rattus norvegicus podocalyxin-like (Podxl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa01723	XM_008762758.2 Latest version!	Rattus norvegicus podocalyxin-like (Podxl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa01723	XM_017592427.1 Latest version!	Rattus norvegicus podocalyxin-like (Podxl), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Podxl ( NM_138848.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620203.1 Rattus norvegicus podocalyxin-like (Podxl), mRNA.

Price & Availability↑

CloneID	ORa01723
Clone ID Related Accession (Same CDS sequence)	XM_008762758.2 , XM_017592427.1 , NM_138848.1
Accession Version	NM_138848.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	podocalyxin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF109393.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF109393.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620203.1
CDS	147..1604
Translation	MRPTLALSALLLLQLLLLSTPSLSQDNGNKTDTSDITSIDQNQDKPATNQPSNATPKSSVQPPTPTSISTSSPDPKATQSSNSSVTTTSDSTTDRTSSSTSTVPTTSNSGQTVSSGGKSSDKITTALPTTLGPVNASSQPTDLNTSTKLPSTPTTNSTASPHQPVSHSEGQHTTVQSSSASVSSSDNTTLLWILTTSKPTGTSEGTQPIAISTPGITTPVSTPLQPTGSPGGTESVPTTEEFTHSTSSWTPVVSQGPSTPSSTWTSGSYKLKCDPAIKPHEELLILNLTRDSFCKGSPPNERFLELLCHSAKASFKPAEDSCALELAPILDNQAVAVKRIVIETKLSPKAVFELLKDKWDDLTEAGVIDIHLGKEGPPEVNEDRFSLPLIITIVCMASFLLLVAALYGCCHQRISQRKDQQRLTEELQTVENGYHDNPTLEVMETPSEMQEKKVVNLNGELGDSWIVPLDNLTKEDLDEEEDTHL

Target ORF information:

RefSeq Version	NM_138848.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus podocalyxin-like (Podxl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138848.1

ORF Insert Sequence:

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Podxl ( XM_008762758.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008760980.1 Rattus norvegicus podocalyxin-like (Podxl), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01723
Clone ID Related Accession (Same CDS sequence)	XM_008762758.2 , XM_017592427.1 , NM_138848.1
Accession Version	XM_008762758.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	podocalyxin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762758.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008760980.1
CDS	330..1787
Translation	MRPTLALSALLLLQLLLLSTPSLSQDNGNKTDTSDITSIDQNQDKPATNQPSNATPKSSVQPPTPTSISTSSPDPKATQSSNSSVTTTSDSTTDRTSSSTSTVPTTSNSGQTVSSGGKSSDKITTALPTTLGPVNASSQPTDLNTSTKLPSTPTTNSTASPHQPVSHSEGQHTTVQSSSASVSSSDNTTLLWILTTSKPTGTSEGTQPIAISTPGITTPVSTPLQPTGSPGGTESVPTTEEFTHSTSSWTPVVSQGPSTPSSTWTSGSYKLKCDPAIKPHEELLILNLTRDSFCKGSPPNERFLELLCHSAKASFKPAEDSCALELAPILDNQAVAVKRIVIETKLSPKAVFELLKDKWDDLTEAGVIDIHLGKEGPPEVNEDRFSLPLIITIVCMASFLLLVAALYGCCHQRISQRKDQQRLTEELQTVENGYHDNPTLEVMETPSEMQEKKVVNLNGELGDSWIVPLDNLTKEDLDEEEDTHL

Target ORF information:

RefSeq Version	XM_008762758.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus podocalyxin-like (Podxl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008762758.2

ORF Insert Sequence:

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Podxl ( XM_017592427.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447916.1 Rattus norvegicus podocalyxin-like (Podxl), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa01723
Clone ID Related Accession (Same CDS sequence)	XM_008762758.2 , XM_017592427.1 , NM_138848.1
Accession Version	XM_017592427.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	podocalyxin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447916.1
CDS	328..1785
Translation	MRPTLALSALLLLQLLLLSTPSLSQDNGNKTDTSDITSIDQNQDKPATNQPSNATPKSSVQPPTPTSISTSSPDPKATQSSNSSVTTTSDSTTDRTSSSTSTVPTTSNSGQTVSSGGKSSDKITTALPTTLGPVNASSQPTDLNTSTKLPSTPTTNSTASPHQPVSHSEGQHTTVQSSSASVSSSDNTTLLWILTTSKPTGTSEGTQPIAISTPGITTPVSTPLQPTGSPGGTESVPTTEEFTHSTSSWTPVVSQGPSTPSSTWTSGSYKLKCDPAIKPHEELLILNLTRDSFCKGSPPNERFLELLCHSAKASFKPAEDSCALELAPILDNQAVAVKRIVIETKLSPKAVFELLKDKWDDLTEAGVIDIHLGKEGPPEVNEDRFSLPLIITIVCMASFLLLVAALYGCCHQRISQRKDQQRLTEELQTVENGYHDNPTLEVMETPSEMQEKKVVNLNGELGDSWIVPLDNLTKEDLDEEEDTHL

Target ORF information:

RefSeq Version	XM_017592427.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus podocalyxin-like (Podxl), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592427.1

ORF Insert Sequence:

ATGCGCCCCA CTCTGGCGCT CTCCGCGCTG CTGTTGCTGC AGCTGCTGTT ACTGTCGACT 
CCATCTCTCT CCCAGGATAA TGGAAATAAG ACTGACACAT CTGATATAAC TAGCATTGAC 
CAGAACCAAG ACAAACCAGC GACAAACCAG CCAAGCAATG CTACACCTAA AAGCTCAGTC 
CAACCTCCAA CACCGACATC TATTTCAACC TCCTCCCCAG ACCCCAAGGC CACTCAAAGC 
AGTAACAGTT CAGTTACAAC TACCAGTGAC TCCACCACTG ACAGGACAAG CTCTTCCACT 
AGCACTGTCC CCACTACTAG CAACAGTGGG CAGACAGTCT CCTCTGGAGG CAAGAGCAGT 
GACAAAATTA CCACAGCCCT ACCAACCACT TTGGGACCAG TCAACGCCTC TTCTCAACCT 
ACTGACCTGA ATACCTCGAC AAAGCTTCCT TCTACCCCCA CAACAAATAG CACAGCAAGC 
CCTCACCAGC CTGTGAGCCA CTCTGAGGGA CAGCACACCA CTGTTCAGAG CAGCTCTGCT 
TCTGTGTCCA GCTCTGACAA CACTACGCTG TTGTGGATAC TTACTACATC CAAACCGACA 
GGCACCTCTG AAGGCACTCA GCCCATCGCT ATCTCGACGC CAGGCATCAC CACACCGGTC 
TCCACACCAC TACAGCCTAC GGGGTCTCCA GGGGGAACTG AGTCGGTGCC TACGACCGAA 
GAATTCACAC ACTCCACTTC TAGTTGGACT CCAGTGGTCT CTCAAGGCCC GAGCACACCC 
TCTTCCACCT GGACGTCTGG GAGTTACAAG CTAAAATGTG ATCCTGCCAT AAAGCCCCAC 
GAGGAACTCC TCATTCTGAA CCTCACAAGA GACAGCTTTT GTAAGGGGAG CCCTCCAAAT 
GAAAGATTCT TGGAACTGCT GTGTCACTCA GCCAAAGCCT CCTTCAAGCC AGCTGAGGAT 
TCGTGTGCTC TGGAGCTGGC CCCCATTCTA GACAACCAGG CGGTGGCAGT GAAGAGAATC 
GTTATTGAGA CGAAGCTTTC TCCTAAGGCT GTGTTTGAAC TGCTGAAGGA CAAATGGGAC 
GACCTGACAG AGGCTGGAGT CATCGACATT CATCTGGGGA AGGAAGGACC TCCAGAAGTC 
AACGAGGACC GCTTCAGCCT TCCTCTCATC ATCACCATCG TCTGCATGGC ATCCTTCCTG 
CTCCTCGTTG CTGCCCTCTA CGGCTGCTGT CACCAGCGGA TCTCCCAGAG GAAGGACCAA 
CAACGACTCA CAGAGGAGCT GCAGACAGTA GAGAATGGTT ACCATGACAA CCCAACCTTG 
GAAGTGATGG AGACTCCTTC TGAGATGCAG GAGAAGAAGG TGGTCAACCT CAACGGGGAG 
CTGGGAGACA GTTGGATCGT CCCTCTGGAC AACTTGACCA AGGAGGACCT AGATGAGGAG 
GAAGATACAC ACCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The effect of connective tissue growth factor on renal fibrosis and podocyte injury in hypertensive rats.
Renal failure36(9)1420-7(2014 Oct)
Lu W,Liu S,Zhao Z,Liu Y,Li T

Expression of caveolin-1 and podocalyxin in rat lungs challenged with 2-kDa macrophage-activating lipopeptide and Flt3L.
Cell and tissue research356(1)207-16(2014 Apr)
Tschernig T,Pabst R,Kasper M,El-Hadi M,Singh B

Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7.
The American journal of pathology176(6)3050-61(2010 Jun)
Hsu YH,Lin WL,Hou YT,Pu YS,Shun CT,Chen CL,Wu YY,Chen JY,Chen TH,Jou TS

Ubiquitous yet distinct expression of podocalyxin on vascular surfaces in normal and tumor tissues in the rat.
Journal of vascular research46(4)311-24(2009)
Testa JE,Chrastina A,Li Y,Oh P,Schnitzer JE

Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation.
Nephron. Experimental nephrology113(3)e89-96(2009)
Kobayashi T,Notoya M,Shinosaki T,Kurihara H

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Podxl cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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