Crlf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crlf2
Entrez Gene ID	171499
Full Name	cytokine receptor-like factor 2
Synonyms	Crl2,Tpte2,Tslpr
General protein information	Preferred Names cytokine receptor-like factor 2 Names cytokine receptor-like factor 2 TSLP receptor thymic stromal lymphopoietin protein receptor thymic stromal-derived lymphopoietin, receptor transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22
Summary	contains conserved WSXWS motif found in all cytokine receptors; binds to the cytokine thymic stromal derived lymphopoietin (TSLP) [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008769916.2	XP_008768138.1	cytokine receptor-like factor 2 isoform X2
NM_134465.2	NP_604460.2	cytokine receptor-like factor 2 precursor
XM_008769915.2	XP_008768137.1	cytokine receptor-like factor 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CRLF2	NP_071431.2
Gallus gallus (chicken)	LOC418668	XP_416864.3
Bos taurus (cattle)	LOC529792	XP_002699496.1
Canis lupus familiaris (dog)	CRLF2	XP_005641109.1
Mus musculus (house mouse)	Crlf2	NP_057924.3
Pan troglodytes (chimpanzee)	CRLF2	XP_001171286.1
Rattus norvegicus (Norway rat)	Crlf2	NP_604460.2

Gene Ontology
Bibliography

Related articles in PubMed

TSLP/TSLPR promote angiogenesis following ischemic stroke via activation of the PI3K/AKT pathway.
Yu X, Peng Y, Liang H, Fu K, Zhao Z, Xie C, Zhou L, Zhang K
Molecular medicine reports17(2)3411-3417(2018 Feb)

Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells.
Allakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S, Paquette N, Ziegler SF, Sarfati M, Delespesse G
The Journal of experimental medicine204(2)253-8(2007 Feb)

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice.
Zhou B, Comeau MR, De Smedt T, Liggitt HD, Dahl ME, Lewis DB, Gyarmati D, Aye T, Campbell DJ, Ziegler SF
Nature immunology6(10)1047-53(2005 Oct)

The murine thymic stromal lymphopoietin receptor is partially expressed with an extracellular C-terminus.
Wikman L, Bostr?m M, J?rnstr?m AC, Lundin K, Nordstr?m T, Lindqvist C
Molecular immunology42(1)49-54(2005 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TSLP receptor is widely expressed in rats suggesting that TSLPR may have roles in signaling outside the hematopoietic system.
Title: Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene.

The following Crlf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crlf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01461	NM_134465.2 Latest version!	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa44342	XM_008769915.2 Latest version!	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa44343	XM_008769916.2 Latest version!	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crlf2 ( NM_134465.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_604460.2 Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), mRNA.

Price & Availability↑

CloneID	ORa01461
Clone ID Related Accession (Same CDS sequence)	NM_134465.2
Accession Version	NM_134465.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Rattus norvegicus(Norway rat)
Product	cytokine receptor-like factor 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078740.1. On Aug 8, 2004 this sequence version replaced NM_134465.1. ##Evidence-Data-START## Transcript exon combination :: BC078740.1, FQ213457.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCTGAGGC CCCGCCCTCC ATGGAACGTC ACCCTGAGCT GGGTAGGGGA CACTGTTGCT 
GTTTCCTGCC CCTCCCACTC TTACCCTGGG CTGGAATATG AGGTGCAGCA CAGAGATGAC 
TTCGACCCTG AATGGCAGTC GACCTCTGCA CCATTCTGCA ACCTGACAGT GGGCGGGCTG 
GACCCTGGGC GCTGCTACGA CTTCCGGGTG CGGGCGACGC CCCAGGATTT CTACTATGGC 
CCCGAGGCGC GGCCCAGCAA GTGGACAGGC GTGGCCAGCC TGCAGGGAGT GGGACCCACA 
GGCTCCTGCA CTGGCCCCAC CCTCCCGAGG ACCCCCGGGA CCCCCACCCC ACCTCTCGCC 
CTGGCCTGTG GCCTTGCGGT GGCCCTGCTC ACCCTGGTGC TGCTCCTGGC CCTGCTGCGG 
ATGCGCAGGG TGAAGGAAGC CCTGCTGCCT GGTGTCCCCG ACCCCCGCGG CTCCTTCCCT 
GGCCTCTTCG AGAAACATCA TGGGAACTTC CAGGCTTGGA TCGCAGATTC TCAGGCTGCT 
GTCCCTACGG TCCCAGAGCA GGACAAAGAT GATGATGTCA TCCGGCCTCA GACCAAGGGG 
GTGGAAACTC AGGAGGAGGA TGATGTCATT GCCCCGGGGT CCCCATGCCT TGGGGGAGGG 
GCCCTGATGT CGGTGGGCGG GGCCTCGTTC CTGATGGGAG ACAGCGGCTA CACCACCCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_604460.2
CDS	98..1180
Translation	MRAVTWAIVAMLLPRVLGAIPTRTPRTGGVGDTLSVAIVCHDLESVEVTWGPGSAHHGLSANLSLEFRYGNQVPQPCPHYFLLDSVRAGCVLPMGKGLLEVVLREGGGAKLFSRKKKASAWLRPRPPWNVTLSWVGDTVAVSCPSHSYPGLEYEVQHRDDFDPEWQSTSAPFCNLTVGGLDPGRCYDFRVRATPQDFYYGPEARPSKWTGVASLQGVGPTGSCTGPTLPRTPGTPTPPLALACGLAVALLTLVLLLALLRMRRVKEALLPGVPDPRGSFPGLFEKHHGNFQAWIADSQAAVPTVPEQDKDDDVIRPQTKGVETQEEDDVIAPGSPCLGGGALMSVGGASFLMGDSGYTTL

Target ORF information:

RefSeq Version	NM_134465.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134465.2

ORF Insert Sequence:

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCTGAGGC CCCGCCCTCC ATGGAACGTC ACCCTGAGCT GGGTAGGGGA CACTGTTGCT 
GTTTCCTGCC CCTCCCACTC TTACCCTGGG CTGGAATATG AGGTGCAGCA CAGAGATGAC 
TTCGACCCTG AATGGCAGTC GACCTCTGCA CCATTCTGCA ACCTGACAGT GGGCGGGCTG 
GACCCTGGGC GCTGCTACGA CTTCCGGGTG CGGGCGACGC CCCAGGATTT CTACTATGGC 
CCCGAGGCGC GGCCCAGCAA GTGGACAGGC GTGGCCAGCC TGCAGGGAGT GGGACCCACA 
GGCTCCTGCA CTGGCCCCAC CCTCCCGAGG ACCCCCGGGA CCCCCACCCC ACCTCTCGCC 
CTGGCCTGTG GCCTTGCGGT GGCCCTGCTC ACCCTGGTGC TGCTCCTGGC CCTGCTGCGG 
ATGCGCAGGG TGAAGGAAGC CCTGCTGCCT GGTGTCCCCG ACCCCCGCGG CTCCTTCCCT 
GGCCTCTTCG AGAAACATCA TGGGAACTTC CAGGCTTGGA TCGCAGATTC TCAGGCTGCT 
GTCCCTACGG TCCCAGAGCA GGACAAAGAT GATGATGTCA TCCGGCCTCA GACCAAGGGG 
GTGGAAACTC AGGAGGAGGA TGATGTCATT GCCCCGGGGT CCCCATGCCT TGGGGGAGGG 
GCCCTGATGT CGGTGGGCGG GGCCTCGTTC CTGATGGGAG ACAGCGGCTA CACCACCCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Crlf2 ( XM_008769915.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768137.1 Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa44342
Clone ID Related Accession (Same CDS sequence)	XM_008769915.2
Accession Version	XM_008769915.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytokine receptor-like factor 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769915.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCGTGAGT GCCCTGGGGG CGGGGCCTGG ACAGTGAGGC CCCGCCCTCC ATGGAACGTC 
ACCCTGAGCT GGGTAGGGGA CACTGTTGCT GTTTCCTGCC CCTCCCACTC TTACCCTGGG 
CTGGAATATG AGGTGCAGCA CAGAGATGAC TTCGACCCTG AATGGCAGTC GACCTCTGCA 
CCATTCTGCA ACCTGACAGT GGGCGGGCTG GACCCTGGGC GCTGCTACGA CTTCCGGGTG 
CGGGCGACGC CCCAGGATTT CTACTATGGC CCCGAGGCGC GGCCCAGCAA GTGGACAGGC 
GTGGCCAGCC TGCAGGGAGT GGGACCCACA GGCTCCTGCA CTGGCCCCAC CCTCCCGAGG 
ACCCCCGGGA CCCCCACCCC ACCTCTCGCC CTGGCCTGTG GCCTTGCGGT GGCCCTGCTC 
ACCCTGGTGC TGCTCCTGGC CCTGCTGCGG ATGCGCAGGG TGAAGGAAGC CCTGCTGCCT 
GGTGTCCCCG ACCCCCGCGG CTCCTTCCCT GGCCTCTTCG AGAAACATCA TGGGAACTTC 
CAGGCTTGGA TCGCAGATTC TCAGGCTGCT GTCCCTACGG TCCCAGAGCA GGACAAAGAT 
GATGATGTCA TCCGGCCTCA GACCAAGGGG GTGGAAACTC AGGAGGAGGA TGATGTCATT 
GCCCCGGGGT CCCCATGCCT TGGGGGAGGG GCCCTGATGT CGGTGGGCGG GGCCTCGTTC 
CTGATGGGAG ACAGCGGCTA CACCACCCTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768137.1
CDS	11..1123
Translation	MRAVTWAIVAMLLPRVLGAIPTRTPRTGGVGDTLSVAIVCHDLESVEVTWGPGSAHHGLSANLSLEFRYGNQVPQPCPHYFLLDSVRAGCVLPMGKGLLEVVLREGGGAKLFSRKKKASAWRECPGGGAWTVRPRPPWNVTLSWVGDTVAVSCPSHSYPGLEYEVQHRDDFDPEWQSTSAPFCNLTVGGLDPGRCYDFRVRATPQDFYYGPEARPSKWTGVASLQGVGPTGSCTGPTLPRTPGTPTPPLALACGLAVALLTLVLLLALLRMRRVKEALLPGVPDPRGSFPGLFEKHHGNFQAWIADSQAAVPTVPEQDKDDDVIRPQTKGVETQEEDDVIAPGSPCLGGGALMSVGGASFLMGDSGYTTL

Target ORF information:

RefSeq Version	XM_008769915.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769915.2

ORF Insert Sequence:

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCGTGAGT GCCCTGGGGG CGGGGCCTGG ACAGTGAGGC CCCGCCCTCC ATGGAACGTC 
ACCCTGAGCT GGGTAGGGGA CACTGTTGCT GTTTCCTGCC CCTCCCACTC TTACCCTGGG 
CTGGAATATG AGGTGCAGCA CAGAGATGAC TTCGACCCTG AATGGCAGTC GACCTCTGCA 
CCATTCTGCA ACCTGACAGT GGGCGGGCTG GACCCTGGGC GCTGCTACGA CTTCCGGGTG 
CGGGCGACGC CCCAGGATTT CTACTATGGC CCCGAGGCGC GGCCCAGCAA GTGGACAGGC 
GTGGCCAGCC TGCAGGGAGT GGGACCCACA GGCTCCTGCA CTGGCCCCAC CCTCCCGAGG 
ACCCCCGGGA CCCCCACCCC ACCTCTCGCC CTGGCCTGTG GCCTTGCGGT GGCCCTGCTC 
ACCCTGGTGC TGCTCCTGGC CCTGCTGCGG ATGCGCAGGG TGAAGGAAGC CCTGCTGCCT 
GGTGTCCCCG ACCCCCGCGG CTCCTTCCCT GGCCTCTTCG AGAAACATCA TGGGAACTTC 
CAGGCTTGGA TCGCAGATTC TCAGGCTGCT GTCCCTACGG TCCCAGAGCA GGACAAAGAT 
GATGATGTCA TCCGGCCTCA GACCAAGGGG GTGGAAACTC AGGAGGAGGA TGATGTCATT 
GCCCCGGGGT CCCCATGCCT TGGGGGAGGG GCCCTGATGT CGGTGGGCGG GGCCTCGTTC 
CTGATGGGAG ACAGCGGCTA CACCACCCTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Crlf2 ( XM_008769916.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768138.1 Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa44343
Clone ID Related Accession (Same CDS sequence)	XM_008769916.2
Accession Version	XM_008769916.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytokine receptor-like factor 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769916.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCGTGAGT GCCCTGGGGG CGGGGCCTGG ACAGTGAGGC CCCGCCCTCC ATGGAACGTC 
ACCCTGAGCT GGGTAGGGGA CACTGTTGCT GTTTCCTGCC CCTCCCACTC TTACCCTGGG 
CTGGAATATG AGGTGCAGCA CAGAGATGAC TTCGACCCTG AATGGCAGGC GAGCAGTGGG 
GCCCGGGCGT GGGTCGACCT CTGCACCATT CTGCAACCTG ACAGTGGGCG GGCTGGACCC 
TGGGCGCTGC TACGACTTCC GGGTGCGGGC GACGCCCCAG GATTTCTACT ATGGCCCCGA 
GGCGCGGCCC AGCAAGTGGA CAGGCGTGGC CAGCCTGCAG GGAGTGGGAC CCACAGGCTC 
CTGCACTGGC CCCACCCTCC CGAGGACCCC CGGGACCCCC ACCCCACCTC TCGCCCTGGC 
CTGTGGCCTT GCGGTGGCCC TGCTCACCCT GGTGCTGCTC CTGGCCCTGC TGCGGATGCG 
CAGGGTGAAG GAAGCCCTGC TGCCTGGTGT CCCCGACCCC CGCGGCTCCT TCCCTGGCCT 
CTTCGAGAAA CATCATGGGA ACTTCCAGGC TTGGATCGCA GATTCTCAGG CTGCTGTCCC 
TACGGTCCCA GAGCAGGACA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768138.1
CDS	11..997
Translation	MRAVTWAIVAMLLPRVLGAIPTRTPRTGGVGDTLSVAIVCHDLESVEVTWGPGSAHHGLSANLSLEFRYGNQVPQPCPHYFLLDSVRAGCVLPMGKGLLEVVLREGGGAKLFSRKKKASAWRECPGGGAWTVRPRPPWNVTLSWVGDTVAVSCPSHSYPGLEYEVQHRDDFDPEWQASSGARAWVDLCTILQPDSGRAGPWALLRLPGAGDAPGFLLWPRGAAQQVDRRGQPAGSGTHRLLHWPHPPEDPRDPHPTSRPGLWPCGGPAHPGAAPGPAADAQGEGSPAAWCPRPPRLLPWPLRETSWELPGLDRRFSGCCPYGPRAGQR

Target ORF information:

RefSeq Version	XM_008769916.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytokine receptor-like factor 2 (Crlf2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769916.2

ORF Insert Sequence:

ATGCGAGCTG TGACCTGGGC CATCGTGGCC ATGCTCCTGC CGCGGGTCTT GGGGGCGATT 
CCGACGAGGA CGCCACGGAC AGGGGGCGTC GGTGACACCC TCTCTGTTGC CATTGTTTGC 
CATGACCTGG AGAGCGTGGA AGTCACGTGG GGCCCGGGCT CTGCCCACCA TGGGCTGTCA 
GCCAATCTCA GCCTGGAGTT CCGGTATGGA AACCAGGTCC CCCAGCCCTG CCCACACTAC 
TTTCTGTTGG ACAGCGTCAG AGCAGGCTGT GTCCTCCCCA TGGGGAAGGG GCTTCTGGAG 
GTGGTGCTGC GTGAGGGAGG CGGAGCCAAG CTGTTCTCCC GGAAGAAGAA GGCATCGGCC 
TGGCGTGAGT GCCCTGGGGG CGGGGCCTGG ACAGTGAGGC CCCGCCCTCC ATGGAACGTC 
ACCCTGAGCT GGGTAGGGGA CACTGTTGCT GTTTCCTGCC CCTCCCACTC TTACCCTGGG 
CTGGAATATG AGGTGCAGCA CAGAGATGAC TTCGACCCTG AATGGCAGGC GAGCAGTGGG 
GCCCGGGCGT GGGTCGACCT CTGCACCATT CTGCAACCTG ACAGTGGGCG GGCTGGACCC 
TGGGCGCTGC TACGACTTCC GGGTGCGGGC GACGCCCCAG GATTTCTACT ATGGCCCCGA 
GGCGCGGCCC AGCAAGTGGA CAGGCGTGGC CAGCCTGCAG GGAGTGGGAC CCACAGGCTC 
CTGCACTGGC CCCACCCTCC CGAGGACCCC CGGGACCCCC ACCCCACCTC TCGCCCTGGC 
CTGTGGCCTT GCGGTGGCCC TGCTCACCCT GGTGCTGCTC CTGGCCCTGC TGCGGATGCG 
CAGGGTGAAG GAAGCCCTGC TGCCTGGTGT CCCCGACCCC CGCGGCTCCT TCCCTGGCCT 
CTTCGAGAAA CATCATGGGA ACTTCCAGGC TTGGATCGCA GATTCTCAGG CTGCTGTCCC 
TACGGTCCCA GAGCAGGACA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TSLP/TSLPR promote angiogenesis following ischemic stroke via activation of the PI3K/AKT pathway.
Molecular medicine reports17(2)3411-3417(2018 Feb)
Yu X,Peng Y,Liang H,Fu K,Zhao Z,Xie C,Zhou L,Zhang K

Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells.
The Journal of experimental medicine204(2)253-8(2007 Feb)
Allakhverdi Z,Comeau MR,Jessup HK,Yoon BR,Brewer A,Chartier S,Paquette N,Ziegler SF,Sarfati M,Delespesse G

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice.
Nature immunology6(10)1047-53(2005 Oct)
Zhou B,Comeau MR,De Smedt T,Liggitt HD,Dahl ME,Lewis DB,Gyarmati D,Aye T,Campbell DJ,Ziegler SF

The murine thymic stromal lymphopoietin receptor is partially expressed with an extracellular C-terminus.
Molecular immunology42(1)49-54(2005 Jan)
Wikman L,Bostr?m M,J?rnstr?m AC,Lundin K,Nordstr?m T,Lindqvist C

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Crlf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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