Atp5f1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atp5f1b
Entrez Gene ID	171374
Full Name	ATP synthase F1 subunit beta
Synonyms	Atp5b
General protein information	Preferred Names ATP synthase F1 subunit beta Names ATP synthase subunit beta, mitochondrial ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide mitochondrial ATP synthase beta subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	beta subunit of rat liver ATP synthase [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134364.1	NP_599191.1	ATP synthase subunit beta, mitochondrial precursor

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	ATPsyn-beta	NP_001259081.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012106	XP_320423.4
Saccharomyces cerevisiae (baker's yeast)	ATP2	NP_012655.3
Arabidopsis thaliana (thale cress)	AT5G08670	NP_568203.2
	ATP5B	XP_001091520.1
Bos taurus (cattle)	ATP5B	NP_786990.1
Mus musculus (house mouse)	Atp5b	NP_058054.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012081	XP_320446.2
Eremothecium gossypii	AGOS_ABR169W	NP_983117.2
Schizosaccharomyces pombe (fission yeast)	atp2	NP_593151.1
Magnaporthe oryzae (rice blast fungus)	MGG_03185	XP_003716804.1
Arabidopsis thaliana (thale cress)	AT5G08680	NP_680155.1
Arabidopsis thaliana (thale cress)	AT5G08690	NP_568204.1
Oryza sativa (rice)	Os05g0553000	NP_001056261.1
Pan troglodytes (chimpanzee)	ATP5B	XP_509149.2
Canis lupus familiaris (dog)	ATP5B	XP_531639.2
Danio rerio (zebrafish)	atp5b	NP_001019600.2
Kluyveromyces lactis	KLLA0D10703g	XP_453538.1
Neurospora crassa	NCU05430	XP_963253.2
Homo sapiens (human)	ATP5B	NP_001677.2
Rattus norvegicus (Norway rat)	Atp5b	NP_599191.1
Gallus gallus (chicken)	ATP5B	NP_001026562.2
Caenorhabditis elegans (roundworm)	atp-2	NP_498111.2
Oryza sativa (rice)	Os01g0685800	NP_001043900.1
Xenopus tropicalis (tropical clawed frog)	atp5b	NP_001001256.1

Gene Ontology
Bibliography

Related articles in PubMed

ATP synthase ?-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus.
Li W, Li SJ, Yin TL, Yang J, Cheng Y
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban37(2)210-216(2017 Apr)

Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies.
Qiu P, Man S, Li J, Liu J, Zhang L, Yu P, Gao W
Journal of agricultural and food chemistry64(13)2765-71(2016 Apr)

Pharmacological inhibition of galectin-1 by lactulose alleviates weight gain in diet-induced obese rats.
Mukherjee R, Yun JW
Life sciences148112-7(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hemoglobin - a novel ligand of hepatocyte ectopic F1-ATPase
Title: Hemoglobin - a novel ligand of hepatocyte ectopic F1-ATPase.

Hyperglycemia may impair mitochondrial function and alter glycolysis in glomerular epithelial cells by down-regulating the expression of ATP synthase beta subunit and enolase 2.
Title: Hyperglycemia decreases the expression of ATP synthase ? subunit and enolase 2 in glomerular epithelial cells.

Increased mitochondrial energy metabolism efficiency via F1F0 ATPase synthase beta subunit contributes to the enhanced synaptic efficacy found in Bcl-x(L)-expressing neurons.
Title: Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.

study shows that the beta-subunit of F1-ATPase is ectopically expressed in the plasma membrane of INS-1 cells and that the appetite regulating peptide enterostatin and fatty acids cause an up-regulation of this protein
Title: Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells.

consumption of soy proteins increases hepatic ATPase activity, which might be a consequence of increased dephosphorylation or decreased phosphorylation of the mitochondrial ATPase/ATP synthase beta protein
Title: Consumption of soy protein isolate modulates the phosphorylation status of hepatic ATPase/ATP synthase beta protein and increases ATPase activity in rats.

The following Atp5f1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atp5f1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12656	NM_134364.1 Latest version!	Rattus norvegicus ATP synthase F1 subunit beta (Atp5f1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atp5f1b ( NM_134364.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599191.1 Rattus norvegicus ATP synthase F1 subunit beta (Atp5f1b), mRNA.

Price & Availability↑

CloneID	ORa12656
Clone ID Related Accession (Same CDS sequence)	NM_134364.1
Accession Version	NM_134364.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	ATP synthase subunit beta, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M25301.1, M19044.1 and M57634.1. On Nov 15, 2004 this sequence version replaced XM_343136.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGTTGAGTC TTGTGGGGCG TGTGGCCTCG GCCTCGGCCT CCGGGGCCTT ACGGGGACTC 
AACCCTTTGG CGGCGCTGCC ACAGGCGCAT CTTCTACTAC GAACCGCTCC CGCCGGGGTC 
CATCCTGCCA GAGACTATGC GGCGCAGTCG TCTGCGGCCC CGAAGGCAGG CACCGCCACC 
GGGCAAATTG TGGCAGTCAT CGGCGCCGTT GTGGATGTCC AGTTCGATGA GGGATTACCA 
CCTATCCTAA ATGCCTTGGA AGTGCAAGGC AGGGAGAGCA GACTGGTTTT GGAGGTAGCC 
CAGCATTTAG GGGAGAGCAC CGTCAGAACT ATTGCTATGG ATGGCACTGA AGGCTTGGTT 
AGAGGCCAGA AAGTACTGGA TTCGGGGGCA CCAATCAAAA TTCCTGTTGG TCCTGAGACC 
TTGGGCAGAA TCATGAATGT CATTGGAGAA CCTATTGATG AGAGAGGTCC TATCAAAACC 
AAACAATTCG CTCCTATTCA TGCTGAGGCT CCTGAATTCA TAGAGATGAG TGTTGAACAG 
GAAATTCTGG TGACTGGTAT AAAGGTTGTG GATCTGCTGG CCCCATACGC CAAGGGTGGG 
AAAATCGGAC TCTTCGGAGG TGCTGGTGTT GGAAAGACAG TACTGATCAT GGAGCTAATC 
AACAATGTTG CTAAAGCCCA TGGTGGTTAT TCTGTATTTG CTGGTGTTGG TGAGAGGACC 
CGTGAGGGCA ATGATTTATA CCATGAAATG ATTGAGTCTG GTGTTATCAA CCTAAAAGAT 
GCCACTTCCA AGGTAGCGTT GGTATATGGG CAGATGAATG AACCGCCTGG TGCTCGTGCC 
CGGGTAGCTC TGACTGGTCT GACTGTTGCT GAATACTTCA GAGACCAGGA AGGCCAAGAT 
GTCCTGCTGT TTATTGACAA CATCTTCCGC TTCACCCAGG CTGGCTCAGA GGTATCTGCC 
TTATTGGGCA GGATCCCGTC TGCTGTAGGC TACCAGCCTA CCCTAGCCAC TGACATGGGT 
ACAATGCAGG AAAGAATCAC CACCACCAAG AAGGGCTCGA TCACCTCAGT GCAGGCTATC 
TATGTGCCAG CTGATGACCT GACTGACCCT GCCCCTGCAA CTACCTTTGC CCATTTGGAT 
GCTACTACTG TGCTGTCCCG TGCTATTGCT GAGTTGGGCA TCTATCCAGC TGTGGATCCA 
CTGGACTCCA CCTCTCGAAT TATGGATCCC AACATCGTTG GCAGTGAGCA TTATGATGTT 
GCTCGTGGGG TGCAAAAGAT CCTGCAGGAC TACAAATCTC TCCAGGACAT CATTGCCATC 
TTGGGTATGG ATGAACTTTC TGAGGAAGAT AAATTGACTG TGTCCAGGGC AAGGAAGATA 
CAGCGCTTCT TGTCACAGCC ATTCCAGGTT GCTGAGGTCT TCACAGGTCA CATGGGAAAG 
CTGGTGCCCC TGAAGGAGAC CATTAAAGGA TTCCAGCAGA TCTTAGCAGG TGACTATGAC 
CATCTCCCGG AACAAGCCTT CTACATGGTG GGACCCATTG AAGAAGCTGT GGCAAAGGCT 
GACAAGCTGG CAGAGGAGCA TGGGTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599191.1
CDS	23..1612
Translation	MLSLVGRVASASASGALRGLNPLAALPQAHLLLRTAPAGVHPARDYAAQSSAAPKAGTATGQIVAVIGAVVDVQFDEGLPPILNALEVQGRESRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGDYDHLPEQAFYMVGPIEEAVAKADKLAEEHGS

Target ORF information:

RefSeq Version	NM_134364.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP synthase F1 subunit beta (Atp5f1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134364.1

ORF Insert Sequence:

ATGTTGAGTC TTGTGGGGCG TGTGGCCTCG GCCTCGGCCT CCGGGGCCTT ACGGGGACTC 
AACCCTTTGG CGGCGCTGCC ACAGGCGCAT CTTCTACTAC GAACCGCTCC CGCCGGGGTC 
CATCCTGCCA GAGACTATGC GGCGCAGTCG TCTGCGGCCC CGAAGGCAGG CACCGCCACC 
GGGCAAATTG TGGCAGTCAT CGGCGCCGTT GTGGATGTCC AGTTCGATGA GGGATTACCA 
CCTATCCTAA ATGCCTTGGA AGTGCAAGGC AGGGAGAGCA GACTGGTTTT GGAGGTAGCC 
CAGCATTTAG GGGAGAGCAC CGTCAGAACT ATTGCTATGG ATGGCACTGA AGGCTTGGTT 
AGAGGCCAGA AAGTACTGGA TTCGGGGGCA CCAATCAAAA TTCCTGTTGG TCCTGAGACC 
TTGGGCAGAA TCATGAATGT CATTGGAGAA CCTATTGATG AGAGAGGTCC TATCAAAACC 
AAACAATTCG CTCCTATTCA TGCTGAGGCT CCTGAATTCA TAGAGATGAG TGTTGAACAG 
GAAATTCTGG TGACTGGTAT AAAGGTTGTG GATCTGCTGG CCCCATACGC CAAGGGTGGG 
AAAATCGGAC TCTTCGGAGG TGCTGGTGTT GGAAAGACAG TACTGATCAT GGAGCTAATC 
AACAATGTTG CTAAAGCCCA TGGTGGTTAT TCTGTATTTG CTGGTGTTGG TGAGAGGACC 
CGTGAGGGCA ATGATTTATA CCATGAAATG ATTGAGTCTG GTGTTATCAA CCTAAAAGAT 
GCCACTTCCA AGGTAGCGTT GGTATATGGG CAGATGAATG AACCGCCTGG TGCTCGTGCC 
CGGGTAGCTC TGACTGGTCT GACTGTTGCT GAATACTTCA GAGACCAGGA AGGCCAAGAT 
GTCCTGCTGT TTATTGACAA CATCTTCCGC TTCACCCAGG CTGGCTCAGA GGTATCTGCC 
TTATTGGGCA GGATCCCGTC TGCTGTAGGC TACCAGCCTA CCCTAGCCAC TGACATGGGT 
ACAATGCAGG AAAGAATCAC CACCACCAAG AAGGGCTCGA TCACCTCAGT GCAGGCTATC 
TATGTGCCAG CTGATGACCT GACTGACCCT GCCCCTGCAA CTACCTTTGC CCATTTGGAT 
GCTACTACTG TGCTGTCCCG TGCTATTGCT GAGTTGGGCA TCTATCCAGC TGTGGATCCA 
CTGGACTCCA CCTCTCGAAT TATGGATCCC AACATCGTTG GCAGTGAGCA TTATGATGTT 
GCTCGTGGGG TGCAAAAGAT CCTGCAGGAC TACAAATCTC TCCAGGACAT CATTGCCATC 
TTGGGTATGG ATGAACTTTC TGAGGAAGAT AAATTGACTG TGTCCAGGGC AAGGAAGATA 
CAGCGCTTCT TGTCACAGCC ATTCCAGGTT GCTGAGGTCT TCACAGGTCA CATGGGAAAG 
CTGGTGCCCC TGAAGGAGAC CATTAAAGGA TTCCAGCAGA TCTTAGCAGG TGACTATGAC 
CATCTCCCGG AACAAGCCTT CTACATGGTG GGACCCATTG AAGAAGCTGT GGCAAAGGCT 
GACAAGCTGG CAGAGGAGCA TGGGTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATP synthase ?-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban37(2)210-216(2017 Apr)
Li W,Li SJ,Yin TL,Yang J,Cheng Y

Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies.
Journal of agricultural and food chemistry64(13)2765-71(2016 Apr)
Qiu P,Man S,Li J,Liu J,Zhang L,Yu P,Gao W

Pharmacological inhibition of galectin-1 by lactulose alleviates weight gain in diet-induced obese rats.
Life sciences148112-7(2016 Mar)
Mukherjee R,Yun JW

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Atp5f1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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