Arr3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arr3
Entrez Gene ID	171107
Full Name	arrestin 3
General protein information	Preferred Names arrestin 3 Names arrestin-C arrestin 3, retinal (X-arrestin) cArr cone arrestin retinal cone arrestin-3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22
Summary	functions in deactivation of G protein-coupled receptors involved in color vision [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601902.1	XP_017457391.1	arrestin-C isoform X3
XM_006257053.3	XP_006257115.1	arrestin-C isoform X2
XM_017601901.1	XP_017457390.1	arrestin-C isoform X1
NM_001190993.1	NP_001177922.1	arrestin-C

Pathways from BioSystems

Homologies

Homo sapiens (human)	ARR3	NP_004303.2
Pan troglodytes (chimpanzee)	ARR3	XP_001152512.1
Danio rerio (zebrafish)	arr3a	NP_001002405.1
Canis lupus familiaris (dog)	ARR3	XP_549059.3
Bos taurus (cattle)	ARR3	NP_776419.1
Mus musculus (house mouse)	Arr3	NP_573468.1
Rattus norvegicus (Norway rat)	Arr3	NP_001177922.1
Gallus gallus (chicken)	ARR3	NP_001091002.1
	ARR3	XP_001085544.2

Gene Ontology
Bibliography

Related articles in PubMed

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.
Willets JM, Nash CA, Rainbow RD, Nelson CP, Challiss RA
American journal of physiology. Cell physiology309(3)C179-89(2015 Aug)

The giant spectrin ?V couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Papal S, Cortese M, Legendre K, Sorusch N, Dragavon J, Sahly I, Shorte S, Wolfrum U, Petit C, El-Amraoui A
Human molecular genetics22(18)3773-88(2013 Sep)

Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.
Morris GE, Nelson CP, Brighton PJ, Standen NB, Challiss RA, Willets JM
American journal of physiology. Cell physiology302(5)C723-34(2012 Mar)

Photoreceptor signaling: supporting vision across a wide range of light intensities.
Arshavsky VY, Burns ME
The Journal of biological chemistry287(3)1620-6(2012 Jan)

Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum.
Bychkov E, Zurkovsky L, Garret MB, Ahmed MR, Gurevich EV
PloS one7(11)e48912(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In early hypertensive phenotype. arrestin3 expression is elevated in resistance arteries.
Title: Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

The effects of arrestin 2 and 3 depletion on endothelin type A and P2Y2 receptor mediated ERK and p38 MAPK signaling, as well as migratory responses are reported
Title: Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.

These data suggest cell type- and subcellular compartment-dependent differences in GRK/arrestin-mediated desensitization and signaling.
Title: Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum.

Arrestin2 and arrestin3 in striatal homogenates bind to the third cytoplasmic loop of the D2 receptor.
Title: Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons.

mutant FSHR displays an approximately 4-fold enhancement in binding affinity for arrestin-3 and an approximately 1.7-fold reduction in maximal arrestin-3 binding capacity
Title: Identification of a short linear sequence present in the C-terminal tail of the rat follitropin receptor that modulates arrestin-3 binding in a phosphorylation-independent fashion.

The following Arr3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arr3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06786	NM_001190993.1 Latest version!	Rattus norvegicus arrestin 3 (Arr3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa06786	XM_006257053.3 Latest version!	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa62998	XM_017601901.1 Latest version!	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62999	XM_017601902.1 Latest version!	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arr3 ( NM_001190993.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001177922.1 Rattus norvegicus arrestin 3 (Arr3), mRNA.

Price & Availability↑

CloneID	ORa06786
Clone ID Related Accession (Same CDS sequence)	XM_006257053.3 , NM_001190993.1
Accession Version	NM_001190993.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	arrestin-C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC141377.3. On Jul 8, 2010 this sequence version replaced XM_001053467.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGTG 
GCTACCAGCT CGGAGGACAT AGTTGTCGAA GAGTTTATGC AGCAGAACAG CCAGACACAA 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177922.1
CDS	1..1146
Translation	MSTVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLKGRKMFVRLTCAFRYGRDDLDVIGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTETVAANSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLMVSYGGILGGLPASDVGVELPLILIHPKPPHGERAVATSSEDIVVEEFMQQNSQTQS

Target ORF information:

RefSeq Version	NM_001190993.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arrestin 3 (Arr3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190993.1

ORF Insert Sequence:

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGTG 
GCTACCAGCT CGGAGGACAT AGTTGTCGAA GAGTTTATGC AGCAGAACAG CCAGACACAA 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arr3 ( XM_006257053.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006257115.1 Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa06786
Clone ID Related Accession (Same CDS sequence)	XM_006257053.3 , NM_001190993.1
Accession Version	XM_006257053.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	arrestin-C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006257053.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGTG 
GCTACCAGCT CGGAGGACAT AGTTGTCGAA GAGTTTATGC AGCAGAACAG CCAGACACAA 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006257115.1
CDS	86..1231
Translation	MSTVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLKGRKMFVRLTCAFRYGRDDLDVIGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTETVAANSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLMVSYGGILGGLPASDVGVELPLILIHPKPPHGERAVATSSEDIVVEEFMQQNSQTQS

Target ORF information:

RefSeq Version	XM_006257053.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006257053.3

ORF Insert Sequence:

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGTG 
GCTACCAGCT CGGAGGACAT AGTTGTCGAA GAGTTTATGC AGCAGAACAG CCAGACACAA 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arr3 ( XM_017601901.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457390.1 Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62998
Clone ID Related Accession (Same CDS sequence)	XM_017601901.1
Accession Version	XM_017601901.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	arrestin-C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGGT 
GAGGCTCCCA GGAACTATTA TCCTGTGGGT TTGGGGCTAA GCAGTTCTCA AAAAAGAGTG 
GCTTCAGGGC TGGAGAGATG GCTCAGAGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457390.1
CDS	86..1258
Translation	MSTVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLKGRKMFVRLTCAFRYGRDDLDVIGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTETVAANSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLMVSYGGILGGLPASDVGVELPLILIHPKPPHGERAGEAPRNYYPVGLGLSSSQKRVASGLERWLRG

Target ORF information:

RefSeq Version	XM_017601901.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601901.1

ORF Insert Sequence:

ATGTCCACAG TGTTTAAAAA GACTAGCTCC AATGGGAAGT TTTCCATCTA CCTGGGGAAA 
CGAGACTTCG TGGATGATGT GGACACAGTG GAGCCCATTG ATGGAGTAAT CCTTGTTGAC 
CCTGAGTACC TAAAAGGTCG AAAGATGTTT GTCAGGTTGA CATGTGCTTT TCGCTATGGC 
CGTGATGACT TGGATGTGAT TGGTCTGACA TTTCGCAAAG ACCTCTATGT ACAGACCAAA 
CAAGTGGCTC CTGCTGAACC CACCAGCATC CAGGGTCCCC TCACAGCCTT ACAGGAGCGG 
CTTCTACACA AGCTTGGGGT CAATGCCTAT CCTTTTACAC TTCAGATGGT TGCTAACCTG 
CCCTGTTCAG TAACACTGCA GCCTGGGCCT GAAGATTCAG GAAAGCCCTG TGGGGTTGAC 
TTTGAAGTGA AGAGTTTCTG TGCAGAAAAT CTGGAAGAGA AAATCTCTAA GAGTGATTCT 
GTGCAGCTGG TTGTACGGAA AGTACAGTTT TCAGCCCTGG AACCAGGCCC TGGTCCCTGG 
GCACAGACCA TTCGCAGCTT CTTTCTGTCA TCTCAGCCCC TTCAACTCCA GGCCTGGATG 
GACAGGGAGG TTCATTACCA TGGAGAAGCT ATTTCTGTAC ACGTTTCTAT CAACAACTAT 
ACCAACAAGG TCATCAGAAG AATCAAGATT GCAGTTATCC AGATCACAGA TGTTGTCCTG 
TATTCACTAG ACAAGTACAC AAAGACTGTG TTCATTCGGG AGTTCACAGA GACAGTAGCT 
GCTAACTCCA GCTTCTCCCA GACCTTTGCA GTAACCCCAC TCCTGGCTGC CAACCGTCAG 
AAGCAGGGCC TGGCACTGGA TGGCAAACTC AAGCATGAAG ACACCAATCT GGCCTCTAGC 
ACAATTCTTC GACCTGGAAT GAACAAGGAG CTACTGGGGA TCCTGGTGTC CTACAAAGTT 
AAAGTCAACT TGATGGTGTC CTATGGGGGC ATTCTAGGAG GTCTGCCAGC CAGTGATGTT 
GGTGTGGAGC TCCCCCTGAT CTTGATCCAT CCAAAGCCAC CTCACGGTGA GAGAGCAGGT 
GAGGCTCCCA GGAACTATTA TCCTGTGGGT TTGGGGCTAA GCAGTTCTCA AAAAAGAGTG 
GCTTCAGGGC TGGAGAGATG GCTCAGAGGT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arr3 ( XM_017601902.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457391.1 Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X3, mRNA.

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CloneID	ORa62999
Clone ID Related Accession (Same CDS sequence)	XM_017601902.1
Accession Version	XM_017601902.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	arrestin-C isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTGTCA GGTTGACATG TGCTTTTCGC TATGGCCGTG ATGACTTGGA TGTGATTGGT 
CTGACATTTC GCAAAGACCT CTATGTACAG ACCAAACAAG TGGCTCCTGC TGAACCCACC 
AGCATCCAGG GTCCCCTCAC AGCCTTACAG GAGCGGCTTC TACACAAGCT TGGGGTCAAT 
GCCTATCCTT TTACACTTCA GATGGTTGCT AACCTGCCCT GTTCAGTAAC ACTGCAGCCT 
GGGCCTGAAG ATTCAGGAAA GCCCTGTGGG GTTGACTTTG AAGTGAAGAG TTTCTGTGCA 
GAAAATCTGG AAGAGAAAAT CTCTAAGAGT GATTCTGTGC AGCTGGTTGT ACGGAAAGTA 
CAGTTTTCAG CCCTGGAACC AGGCCCTGGT CCCTGGGCAC AGACCATTCG CAGCTTCTTT 
CTGTCATCTC AGCCCCTTCA ACTCCAGGCC TGGATGGACA GGGAGGTTCA TTACCATGGA 
GAAGCTATTT CTGTACACGT TTCTATCAAC AACTATACCA ACAAGGTCAT CAGAAGAATC 
AAGATTGCAG TTATCCAGAT CACAGATGTT GTCCTGTATT CACTAGACAA GTACACAAAG 
ACTGTGTTCA TTCGGGAGTT CACAGAGACA GTAGCTGCTA ACTCCAGCTT CTCCCAGACC 
TTTGCAGTAA CCCCACTCCT GGCTGCCAAC CGTCAGAAGC AGGGCCTGGC ACTGGATGGC 
AAACTCAAGC ATGAAGACAC CAATCTGGCC TCTAGCACAA TTCTTCGACC TGGAATGAAC 
AAGGAGCTAC TGGGGATCCT GGTGTCCTAC AAAGTTAAAG TCAACTTGAT GGTGTCCTAT 
GGGGGCATTC TAGGAGGTCT GCCAGCCAGT GATGTTGGTG TGGAGCTCCC CCTGATCTTG 
ATCCATCCAA AGCCACCTCA CGGTGAGAGA GCAGGTGAGG CTCCCAGGAA CTATTATCCT 
GTGGGTTTGG GGCTAAGCAG TTCTCAAAAA AGAGTGGCTT CAGGGCTGGA GAGATGGCTC 
AGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457391.1
CDS	137..1165
Translation	MFVRLTCAFRYGRDDLDVIGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTETVAANSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLMVSYGGILGGLPASDVGVELPLILIHPKPPHGERAGEAPRNYYPVGLGLSSSQKRVASGLERWLRG

Target ORF information:

RefSeq Version	XM_017601902.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arrestin 3, retinal (X-arrestin) (Arr3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601902.1

ORF Insert Sequence:

ATGTTTGTCA GGTTGACATG TGCTTTTCGC TATGGCCGTG ATGACTTGGA TGTGATTGGT 
CTGACATTTC GCAAAGACCT CTATGTACAG ACCAAACAAG TGGCTCCTGC TGAACCCACC 
AGCATCCAGG GTCCCCTCAC AGCCTTACAG GAGCGGCTTC TACACAAGCT TGGGGTCAAT 
GCCTATCCTT TTACACTTCA GATGGTTGCT AACCTGCCCT GTTCAGTAAC ACTGCAGCCT 
GGGCCTGAAG ATTCAGGAAA GCCCTGTGGG GTTGACTTTG AAGTGAAGAG TTTCTGTGCA 
GAAAATCTGG AAGAGAAAAT CTCTAAGAGT GATTCTGTGC AGCTGGTTGT ACGGAAAGTA 
CAGTTTTCAG CCCTGGAACC AGGCCCTGGT CCCTGGGCAC AGACCATTCG CAGCTTCTTT 
CTGTCATCTC AGCCCCTTCA ACTCCAGGCC TGGATGGACA GGGAGGTTCA TTACCATGGA 
GAAGCTATTT CTGTACACGT TTCTATCAAC AACTATACCA ACAAGGTCAT CAGAAGAATC 
AAGATTGCAG TTATCCAGAT CACAGATGTT GTCCTGTATT CACTAGACAA GTACACAAAG 
ACTGTGTTCA TTCGGGAGTT CACAGAGACA GTAGCTGCTA ACTCCAGCTT CTCCCAGACC 
TTTGCAGTAA CCCCACTCCT GGCTGCCAAC CGTCAGAAGC AGGGCCTGGC ACTGGATGGC 
AAACTCAAGC ATGAAGACAC CAATCTGGCC TCTAGCACAA TTCTTCGACC TGGAATGAAC 
AAGGAGCTAC TGGGGATCCT GGTGTCCTAC AAAGTTAAAG TCAACTTGAT GGTGTCCTAT 
GGGGGCATTC TAGGAGGTCT GCCAGCCAGT GATGTTGGTG TGGAGCTCCC CCTGATCTTG 
ATCCATCCAA AGCCACCTCA CGGTGAGAGA GCAGGTGAGG CTCCCAGGAA CTATTATCCT 
GTGGGTTTGG GGCTAAGCAG TTCTCAAAAA AGAGTGGCTT CAGGGCTGGA GAGATGGCTC 
AGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.
American journal of physiology. Cell physiology309(3)C179-89(2015 Aug)
Willets JM,Nash CA,Rainbow RD,Nelson CP,Challiss RA

The giant spectrin ?V couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Human molecular genetics22(18)3773-88(2013 Sep)
Papal S,Cortese M,Legendre K,Sorusch N,Dragavon J,Sahly I,Shorte S,Wolfrum U,Petit C,El-Amraoui A

Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.
American journal of physiology. Cell physiology302(5)C723-34(2012 Mar)
Morris GE,Nelson CP,Brighton PJ,Standen NB,Challiss RA,Willets JM

Photoreceptor signaling: supporting vision across a wide range of light intensities.
The Journal of biological chemistry287(3)1620-6(2012 Jan)
Arshavsky VY,Burns ME

Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum.
PloS one7(11)e48912(2012)
Bychkov E,Zurkovsky L,Garret MB,Ahmed MR,Gurevich EV

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Arr3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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