Inpp5j cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Inpp5j
Entrez Gene ID	171088
Full Name	inositol polyphosphate-5-phosphatase J
Synonyms	Inpp,Pib5pa,Pipp
General protein information	Preferred Names inositol polyphosphate-5-phosphatase J Names phosphatidylinositol 4,5-bisphosphate 5-phosphatase A proline-rich inositol polyphosphate 5-phosphatase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14q21
Summary	hydrolyzes phosphate at the D-5 position of inositol or phosphatidylinositol polyphosphates; may mediate the level of inositol and phosphatidylinositol polyphosphates at membrane ruffles [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133562.1	NP_598246.1	phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
XM_006251155.3	XP_006251217.1	phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	INPP5J	XP_005636520.1
Gallus gallus (chicken)	INPP5J	XP_415287.4
Pan troglodytes (chimpanzee)	INPP5J	XP_003953911.1
Mus musculus (house mouse)	Inpp5j	NP_766027.2
Homo sapiens (human)	INPP5J	NP_001271214.1
	INPP5J	XP_002798372.1
Danio rerio (zebrafish)	inpp5jb	XP_002662241.3
Rattus norvegicus (Norway rat)	Inpp5j	NP_598246.1
Drosophila melanogaster (fruit fly)	CG6805	NP_001246379.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)?collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.
Astle MV, Ooms LM, Cole AR, Binge LC, Dyson JM, Layton MJ, Petratos S, Sutherland C, Mitchell CA
The Journal of biological chemistry286(26)23407-18(2011 Jul)

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
Ooms LM, Fedele CG, Astle MV, Ivetac I, Cheung V, Pearson RB, Layton MJ, Forrai A, Nandurkar HH, Mitchell CA
Molecular biology of the cell17(2)607-22(2006 Feb)

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.
Gurung R, Tan A, Ooms LM, McGrath MJ, Huysmans RD, Munday AD, Prescott M, Whisstock JC, Mitchell CA
The Journal of biological chemistry278(13)11376-85(2003 Mar)

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.
Woodcock EA, Wang BH, Arthur JF, Lennard A, Matkovich SJ, Du XJ, Brown JH, Hannan RD
The Journal of biological chemistry277(25)22734-42(2002 Jun)

Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy.
Patel S, Yenush L, Rodr?guez PL, Serrano R, Blundell TL
Journal of molecular biology315(4)677-85(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PIPP and CRMP2 exert opposing roles in promoting axon selection and neurite elongation and the complex between these proteins serves to regulate the localization of effectors that promote neurite extension.
Title: Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)?collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.
Title: Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.

crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy
Title: Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy.

The following Inpp5j gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Inpp5j cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa36197	XM_006251155.3 Latest version!	Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa00941	NM_133562.1 Latest version!	Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Inpp5j ( XM_006251155.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251217.1 Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36197
Clone ID Related Accession (Same CDS sequence)	XM_006251155.3
Accession Version	XM_006251155.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2985bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251155.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGCC AGAGCAGGAG TGGTAGTGCC AAGTCGGGGA CCAGAACTGG ACTGGGACCC 
TTGCCTGGGA CCCATGGGGC TTTGCAAACT GGGACACCCT CGAAGCTTCC AGCAAAGAAC 
ACGGGCCCAA CACCCTCAGA ACCAAGATTG GCCCTGGCAC CGGTGGGACC ACGAGCAGCT 
GTGTCACCTC CTTCAGAGAG ACCAAGACTG GCTTTGTCAT CTCCCCGACC CATCCTAGCT 
CCACTGTCCA CCGCTGGCGA ACAGAAAAGA CCTCCACCTC ACCGCAGCTC CAAGCCGGCT 
CCCACGTCTG TGGGCCAACT GGTAGTATCT GCCGCTGCAG GACCAAAGCC TCCGCCAGTC 
GCCTCGGTCT CAATCCTGGC TCCGAAGTCT CTGGGGCAGC TAGTAATATC TGCCTCTGCT 
ATGCCAAGGC CTACTCCGGC TCCTCTAGGG CCCATTCTAT CACCAACTTC CAGGGATCAG 
AAGCAGTTAT CACCCACCTC TGTGGGACCT AAGCCAGCAT TGGCAACCTC AGGCCTAAGC 
CTGGCACTGG CCTCTCAGGA GCAGCCCCCA CAGTCCCCCT CCAGTCCTTC CCCTGTGCCC 
AGTCCCGTTC TGTCACCCTC TCAGGAGAGT CACCTGGCTC CAGCAACTGT GACATCTACC 
CCAGCTTCCG AGAGACAGTT GCCAGCTAGA CAGAAGGATA CGGCAGTTCG CAGGCCCATT 
CCCCCTGCAG ACGGGTGTCT CCATACCCCA GTGCAGGCAG CTGGTCTTGC CACCTCTCCT 
CCAAGGGCCC AAACTTCCTC AGATCCTCGG CTTTCCCCCT CCTTCCGCGC AAGACCAGAG 
GCTCCGCGCC ACAGTCCCGA GGATCCCGTC TTGCCGCCGC CACCACAGAC CCTGCCCTTG 
GATGTGAGCT CAGGCCTTCC AGAGTCTGGC ACCCGCTCCC CTGGACTTCT GTCCCCTACC 
TTTCGGCCAG GAATCCCTTC AAACCAGACT GTGCCCCCAC CTCTGCCCAA GCCACCTCGG 
TCTCCCAGCC GCTCCCCTAG TCGTTCTCCC AACCGCTCTC CCTGTGTGCC CCCAGCCCCT 
GAGGTGGCAC TCCCAAGACC TGTCACCCAG GGTGCAGGGC CTGGCAAGTG CCCAAGCCCT 
AACCTACAGA CACAAGAAAG CCCAGTCGCC ACCGCCACCT CACCAACGTC TTCTTGGTCA 
GCTCAGCCTA CCTGCAAGAG CGACCCTGGA TTCCGGATCA CTGTGGTTAC ATGGAATGTG 
GGCACTGCCA TGCCTCCTGA CGATGTCACA TCTCTTCTAC ACCTGGGTGG TGGCCACGAT 
AGCGACGGTG CAGACATGAT TGCCATCGGG TTGCAAGAAG TCAATTCCAT GATCAACAAG 
CGGCTCAAGG ATGCTCTCTT TACCGACCAG TGGAGTGAGC TCTTCATGGA TGCGCTGGGG 
CCTTTCAACT TCGTGCTGGT GAGCACCGTG AGGATGCAGG GCGTCATCCT GCTGCTCTTC 
GCCAAGTACT ACCACCTACC CTTCCTACGG GATGTGCAGA CGGACTGTAC TCGGACTGGC 
CTGGGTGGCT ACTGGGGTAA CAAGGGCGGA GTAAGTGTGC GCTTAGCAGC CTTCGGGCAC 
ATGCTGTGCT TCCTAAACTG CCACTTGCCC GCACACATGG ACAAGGCGGA GCAGCGCAAG 
GATAACTTTC AAACTATCCT TAGCCTCCAG CAATTCCAGG GACCTGGTGC ACACGGCATC 
CTGGATCATG ACCTTGTATT CTGGTTTGGG GACCTGAACT TCCGCATTGA GAGCTATGAC 
CTACACTTCG TCAAGTTCGC CATAGACAGC AACCAACTCC ATCAGCTCTG GGAGAAGGAC 
CAGCTCAACA TGGCCAAGAA TACTTGGCCC ATCTTGAAAG GTTTCCAGGA AGGGCCCCTT 
AATTTTGCCC CCACCTTCAA GTTTGATGTG GGGACCAACA AATATGATAC GAGTGCCAAG 
AAGCGGAAGC CAGCCTGGAC AGATCGCATT CTGTGGAAGG TCAAGGCTCC AAGTGGAGGC 
CCCAGCCCCT CAGGGCGAGA GAGTCACAGG CTCCAGGTGA CCCAGCACAG CTATCGCAGT 
CACATGGAAT ACACCGTCAG TGACCACAAG CCTGTTGCCG CCCGCTTCCT TCTGCAGTTT 
GCCTTCAGGG ATGATGTACC TCTGGTACGG CTGGAGGTGG CGGACGAGTG GGCAAGGCCG 
GAGCAGGCTG TGGTGAGATA CCGCGTGGAA ACAGTATTTG CCCGAAGCTC CTGGGACTGG 
ATTGGCTTGT ACCGGGTGGG TTTCCGTCAC TGTAAGGATT ATGTGGCTTA TGTCTGGGCC 
AAGCATGAAG AAGTGGATGG GAATATCTAC CAGGTGACCT TCAGTGAGGA GTCACTGCCC 
AAGGGCCATG GCGACTTCAT CCTGGGTTAC TATAGCCACC ACCACAGCAT CCTCATTGGT 
GTCACAGAAC CCTTTCAGAT CTCGCTGCCT ACCTCAGAAT CAGCCAGCAG CAGCACAGAC 
AGCTCAGGCA CCAGCTCCGA GGGGGAGGAT GACAGCACTC TGGAGCTGCT GGCACCCAAG 
TCCCGCAGCC CCAGCCCTGG CAAGTCCAAG AGACACCGTA GTCGCAGCCC GGGCCTAGCA 
CGCTTCCCCA GTCTCGCTCT CCGTCCCTCA TCCCGCGAAC GCCGTGGTGG CAGCCGTAGT 
CCCTCACCCC AGAGCCGCCA GCTGCCTCGG GTAGCCCCCG ACAGGGGTCA CAGTAGTGGC 
AGCCGAGGTA GTAGTGAGGA GGGGCCCTCT GGGCCGCCTG GACCCTGGGC CTTCCCACCA 
GCTGTGCCTC GAAGCCTGGG CCTGCTTCCA GCCTTGCGCC TGGAGACCGT AGACCCAGGT 
GGCGGAGGCT CCTGGGGACC TGACCAGGAG GCCCCTGACC CTAATAGCCT GTCCCCCAGC 
CCGCAGGGCA GGCTGGGGCT AGAGGACGGG GGTTTGGGGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251217.1
CDS	90..3074
Translation	MEGQSRSGSAKSGTRTGLGPLPGTHGALQTGTPSKLPAKNTGPTPSEPRLALAPVGPRAAVSPPSERPRLALSSPRPILAPLSTAGEQKRPPPHRSSKPAPTSVGQLVVSAAAGPKPPPVASVSILAPKSLGQLVISASAMPRPTPAPLGPILSPTSRDQKQLSPTSVGPKPALATSGLSLALASQEQPPQSPSSPSPVPSPVLSPSQESHLAPATVTSTPASERQLPARQKDTAVRRPIPPADGCLHTPVQAAGLATSPPRAQTSSDPRLSPSFRARPEAPRHSPEDPVLPPPPQTLPLDVSSGLPESGTRSPGLLSPTFRPGIPSNQTVPPPLPKPPRSPSRSPSRSPNRSPCVPPAPEVALPRPVTQGAGPGKCPSPNLQTQESPVATATSPTSSWSAQPTCKSDPGFRITVVTWNVGTAMPPDDVTSLLHLGGGHDSDGADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAHGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSNQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPSGGPSPSGRESHRLQVTQHSYRSHMEYTVSDHKPVAARFLLQFAFRDDVPLVRLEVADEWARPEQAVVRYRVETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEEVDGNIYQVTFSEESLPKGHGDFILGYYSHHHSILIGVTEPFQISLPTSESASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPSLALRPSSRERRGGSRSPSPQSRQLPRVAPDRGHSSGSRGSSEEGPSGPPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDQEAPDPNSLSPSPQGRLGLEDGGLGP

Target ORF information:

RefSeq Version	XM_006251155.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251155.3

ORF Insert Sequence:

ATGGAGGGCC AGAGCAGGAG TGGTAGTGCC AAGTCGGGGA CCAGAACTGG ACTGGGACCC 
TTGCCTGGGA CCCATGGGGC TTTGCAAACT GGGACACCCT CGAAGCTTCC AGCAAAGAAC 
ACGGGCCCAA CACCCTCAGA ACCAAGATTG GCCCTGGCAC CGGTGGGACC ACGAGCAGCT 
GTGTCACCTC CTTCAGAGAG ACCAAGACTG GCTTTGTCAT CTCCCCGACC CATCCTAGCT 
CCACTGTCCA CCGCTGGCGA ACAGAAAAGA CCTCCACCTC ACCGCAGCTC CAAGCCGGCT 
CCCACGTCTG TGGGCCAACT GGTAGTATCT GCCGCTGCAG GACCAAAGCC TCCGCCAGTC 
GCCTCGGTCT CAATCCTGGC TCCGAAGTCT CTGGGGCAGC TAGTAATATC TGCCTCTGCT 
ATGCCAAGGC CTACTCCGGC TCCTCTAGGG CCCATTCTAT CACCAACTTC CAGGGATCAG 
AAGCAGTTAT CACCCACCTC TGTGGGACCT AAGCCAGCAT TGGCAACCTC AGGCCTAAGC 
CTGGCACTGG CCTCTCAGGA GCAGCCCCCA CAGTCCCCCT CCAGTCCTTC CCCTGTGCCC 
AGTCCCGTTC TGTCACCCTC TCAGGAGAGT CACCTGGCTC CAGCAACTGT GACATCTACC 
CCAGCTTCCG AGAGACAGTT GCCAGCTAGA CAGAAGGATA CGGCAGTTCG CAGGCCCATT 
CCCCCTGCAG ACGGGTGTCT CCATACCCCA GTGCAGGCAG CTGGTCTTGC CACCTCTCCT 
CCAAGGGCCC AAACTTCCTC AGATCCTCGG CTTTCCCCCT CCTTCCGCGC AAGACCAGAG 
GCTCCGCGCC ACAGTCCCGA GGATCCCGTC TTGCCGCCGC CACCACAGAC CCTGCCCTTG 
GATGTGAGCT CAGGCCTTCC AGAGTCTGGC ACCCGCTCCC CTGGACTTCT GTCCCCTACC 
TTTCGGCCAG GAATCCCTTC AAACCAGACT GTGCCCCCAC CTCTGCCCAA GCCACCTCGG 
TCTCCCAGCC GCTCCCCTAG TCGTTCTCCC AACCGCTCTC CCTGTGTGCC CCCAGCCCCT 
GAGGTGGCAC TCCCAAGACC TGTCACCCAG GGTGCAGGGC CTGGCAAGTG CCCAAGCCCT 
AACCTACAGA CACAAGAAAG CCCAGTCGCC ACCGCCACCT CACCAACGTC TTCTTGGTCA 
GCTCAGCCTA CCTGCAAGAG CGACCCTGGA TTCCGGATCA CTGTGGTTAC ATGGAATGTG 
GGCACTGCCA TGCCTCCTGA CGATGTCACA TCTCTTCTAC ACCTGGGTGG TGGCCACGAT 
AGCGACGGTG CAGACATGAT TGCCATCGGG TTGCAAGAAG TCAATTCCAT GATCAACAAG 
CGGCTCAAGG ATGCTCTCTT TACCGACCAG TGGAGTGAGC TCTTCATGGA TGCGCTGGGG 
CCTTTCAACT TCGTGCTGGT GAGCACCGTG AGGATGCAGG GCGTCATCCT GCTGCTCTTC 
GCCAAGTACT ACCACCTACC CTTCCTACGG GATGTGCAGA CGGACTGTAC TCGGACTGGC 
CTGGGTGGCT ACTGGGGTAA CAAGGGCGGA GTAAGTGTGC GCTTAGCAGC CTTCGGGCAC 
ATGCTGTGCT TCCTAAACTG CCACTTGCCC GCACACATGG ACAAGGCGGA GCAGCGCAAG 
GATAACTTTC AAACTATCCT TAGCCTCCAG CAATTCCAGG GACCTGGTGC ACACGGCATC 
CTGGATCATG ACCTTGTATT CTGGTTTGGG GACCTGAACT TCCGCATTGA GAGCTATGAC 
CTACACTTCG TCAAGTTCGC CATAGACAGC AACCAACTCC ATCAGCTCTG GGAGAAGGAC 
CAGCTCAACA TGGCCAAGAA TACTTGGCCC ATCTTGAAAG GTTTCCAGGA AGGGCCCCTT 
AATTTTGCCC CCACCTTCAA GTTTGATGTG GGGACCAACA AATATGATAC GAGTGCCAAG 
AAGCGGAAGC CAGCCTGGAC AGATCGCATT CTGTGGAAGG TCAAGGCTCC AAGTGGAGGC 
CCCAGCCCCT CAGGGCGAGA GAGTCACAGG CTCCAGGTGA CCCAGCACAG CTATCGCAGT 
CACATGGAAT ACACCGTCAG TGACCACAAG CCTGTTGCCG CCCGCTTCCT TCTGCAGTTT 
GCCTTCAGGG ATGATGTACC TCTGGTACGG CTGGAGGTGG CGGACGAGTG GGCAAGGCCG 
GAGCAGGCTG TGGTGAGATA CCGCGTGGAA ACAGTATTTG CCCGAAGCTC CTGGGACTGG 
ATTGGCTTGT ACCGGGTGGG TTTCCGTCAC TGTAAGGATT ATGTGGCTTA TGTCTGGGCC 
AAGCATGAAG AAGTGGATGG GAATATCTAC CAGGTGACCT TCAGTGAGGA GTCACTGCCC 
AAGGGCCATG GCGACTTCAT CCTGGGTTAC TATAGCCACC ACCACAGCAT CCTCATTGGT 
GTCACAGAAC CCTTTCAGAT CTCGCTGCCT ACCTCAGAAT CAGCCAGCAG CAGCACAGAC 
AGCTCAGGCA CCAGCTCCGA GGGGGAGGAT GACAGCACTC TGGAGCTGCT GGCACCCAAG 
TCCCGCAGCC CCAGCCCTGG CAAGTCCAAG AGACACCGTA GTCGCAGCCC GGGCCTAGCA 
CGCTTCCCCA GTCTCGCTCT CCGTCCCTCA TCCCGCGAAC GCCGTGGTGG CAGCCGTAGT 
CCCTCACCCC AGAGCCGCCA GCTGCCTCGG GTAGCCCCCG ACAGGGGTCA CAGTAGTGGC 
AGCCGAGGTA GTAGTGAGGA GGGGCCCTCT GGGCCGCCTG GACCCTGGGC CTTCCCACCA 
GCTGTGCCTC GAAGCCTGGG CCTGCTTCCA GCCTTGCGCC TGGAGACCGT AGACCCAGGT 
GGCGGAGGCT CCTGGGGACC TGACCAGGAG GCCCCTGACC CTAATAGCCT GTCCCCCAGC 
CCGCAGGGCA GGCTGGGGCT AGAGGACGGG GGTTTGGGGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inpp5j ( NM_133562.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598246.1 Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), mRNA.

Price & Availability↑

CloneID	ORa00941
Clone ID Related Accession (Same CDS sequence)	NM_133562.1
Accession Version	NM_133562.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3006bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB032551.1. ##Evidence-Data-START## Transcript exon combination :: AB032551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGCC AGAGCAGGAG TGGTAGTGCC AAGTCGGGGA CCAGAACTGG ACTGGGACCC 
TTGCCTGGGA CCCATGGGGC TTTGCAAACT GGGACACCCT CGAAGAAGGT AAATTCAAGT 
TTTCAGCTTC CAGCAAAGAA CACGGGCCCA ACACCCTCAG AACCAAGATT GGCCCTGGCA 
CCGGTGGGAC CACGAGCAGC TGTGTCACCT CCTTCAGAGA GACCAAGACT GGCTTTGTCA 
TCTCCCCGAC CCATCCTAGC TCCACTGTCC ACCGCTGGCG AACAGAAAAG ACCTCCACCT 
CACCGCAGCT CCAAGCCGGC TCCCACGTCT GTGGGCCAAC TGGTAGTATC TGCCGCTGCA 
GGACCAAAGC CTCCGCCAGT CGCCTCGGTC TCAATCCTGG CTCCGAAGTC TCTGGGGCAG 
CTAGTAATAT CTGCCTCTGC TATGCCAAGG CCTACTCCGG CTCCTCTAGG GCCCATTCTA 
TCACCAACTT CCAGGGATCA GAAGCAGTTA TCACCCACCT CTGTGGGACC TAAGCCAGCA 
TTGGCAACCT CAGGCCTAAG CCTGGCACTG GCCTCTCAGG AGCAGCCCCC ACAGTCCCCC 
TCCAGTCCTT CCCCTGTGCC CAGTCCCGTT CTGTCACCCT CTCAGGAGAG TCACCTGGCT 
CCAGCAACTG TGACATCTAC CCCAGCTTCC GAGAGACAGT TGCCAGCTAG ACAGAAGGAT 
ACGGCAGTTC GCAGGCCCAT TCCCCCTGCA GACGGGTGTC TCCATACCCC AGTGCAGGCA 
GCTGGTCTTG CCACCTCTCC TCCAAGGGCC CAAACTTCCT CAGATCCTCG GCTTTCCCCC 
TCCTTCCGCG CAAGACCAGA GGCTCCGCGC CACAGTCCCG AGGATCCCGT CTTGCCGCCG 
CCACCACAGA CCCTGCCCTT GGATGTGAGC TCAGGCCTTC CAGAGTCTGG CACCCGCTCC 
CCTGGACTTC TGTCCCCTAC CTTTCGGCCA GGAATCCCTT CAAACCAGAC TGTGCCCCCA 
CCTCTGCCCA AGCCACCTCG GTCTCCCAGC CGCTCCCCTA GTCGTTCTCC CAACCGCTCT 
CCCTGTGTGC CCCCAGCCCC TGAGGTGGCA CTCCCAAGAC CTGTCACCCA GGGTGCAGGG 
CCTGGCAAGT GCCCAAGCCC TAACCTACAG ACACAAGAAA GCCCAGTCGC CACCGCCACC 
TCACCAACGT CTTCTTGGTC AGCTCAGCCT ACCTGCAAGA GCGACCCTGG ATTCCGGATC 
ACTGTGGTTA CATGGAATGT GGGCACTGCC ATGCCTCCTG ACGATGTCAC ATCTCTTCTA 
CACCTGGGTG GTGGCCACGA TAGCGACGGT GCAGACATGA TTGCCATCGG GTTGCAAGAA 
GTCAATTCCA TGATCAACAA GCGGCTCAAG GATGCTCTCT TTACCGACCA GTGGAGTGAG 
CTCTTCATGG ATGCGCTGGG GCCTTTCAAC TTCGTGCTGG TGAGCACCGT GAGGATGCAG 
GGCGTCATCC TGCTGCTCTT CGCCAAGTAC TACCACCTAC CCTTCCTACG GGATGTGCAG 
ACGGACTGTA CTCGGACTGG CCTGGGTGGC TACTGGGGTA ACAAGGGCGG AGTAAGTGTG 
CGCTTAGCAG CCTTCGGGCA CATGCTGTGC TTCCTAAACT GCCACTTGCC CGCACACATG 
GACAAGGCGG AGCAGCGCAA GGATAACTTT CAAACTATCC TTAGCCTCCA GCAATTCCAG 
GGACCTGGTG CACACGGCAT CCTGGATCAT GACCTTGTAT TCTGGTTTGG GGACCTGAAC 
TTCCGCATTG AGAGCTATGA CCTACACTTC GTCAAGTTCG CCATAGACAG CAACCAACTC 
CATCAGCTCT GGGAGAAGGA CCAGCTCAAC ATGGCCAAGA ATACTTGGCC CATCTTGAAA 
GGTTTCCAGG AAGGGCCCCT TAATTTTGCC CCCACCTTCA AGTTTGATGT GGGGACCAAC 
AAATATGATA CGAGTGCCAA GAAGCGGAAG CCAGCCTGGA CAGATCGCAT TCTGTGGAAG 
GTCAAGGCTC CAAGTGGAGG CCCCAGCCCC TCAGGGCGAG AGAGTCACAG GCTCCAGGTG 
ACCCAGCACA GCTATCGCAG TCACATGGAA TACACCGTCA GTGACCACAA GCCTGTTGCC 
GCCCGCTTCC TTCTGCAGTT TGCCTTCAGG GATGATGTAC CTCTGGTACG GCTGGAGGTG 
GCGGACGAGT GGGCAAGGCC GGAGCAGGCT GTGGTGAGAT ACCGCGTGGA AACAGTATTT 
GCCCGAAGCT CCTGGGACTG GATTGGCTTG TACCGGGTGG GTTTCCGTCA CTGTAAGGAT 
TATGTGGCTT ATGTCTGGGC CAAGCATGAA GAAGTGGATG GGAATATCTA CCAGGTGACC 
TTCAGTGAGG AGTCACTGCC CAAGGGCCAT GGCGACTTCA TCCTGGGTTA CTATAGCCAC 
CACCACAGCA TCCTCATTGG TGTCACAGAA CCCTTTCAGA TCTCGCTGCC TACCTCAGAA 
TCAGCCAGCA GCAGCACAGA CAGCTCAGGC ACCAGCTCCG AGGGGGAGGA TGACAGCACT 
CTGGAGCTGC TGGCACCCAA GTCCCGCAGC CCCAGCCCTG GCAAGTCCAA GAGACACCGT 
AGTCGCAGCC CGGGCCTAGC ACGCTTCCCC AGTCTCGCTC TCCGTCCCTC ATCCCGCGAA 
CGCCGTGGTG GCAGCCGTAG TCCCTCACCC CAGAGCCGCC AGCTGCCTCG GGTAGCCCCC 
GACAGGGGTC ACAGTAGTGG CAGCCGAGGT AGTAGTGAGG AGGGGCCCTC TGGGCCGCCT 
GGACCCTGGG CCTTCCCACC AGCTGTGCCT CGAAGCCTGG GCCTGCTTCC AGCCTTGCGC 
CTGGAGACCG TAGACCCAGG TGGCGGAGGC TCCTGGGGAC CTGACCAGGA GGCCCCTGAC 
CCTAATAGCC TGTCCCCCAG CCCGCAGGGC AGGCTGGGGC TAGAGGACGG GGGTTTGGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598246.1
CDS	43..3048
Translation	MEGQSRSGSAKSGTRTGLGPLPGTHGALQTGTPSKKVNSSFQLPAKNTGPTPSEPRLALAPVGPRAAVSPPSERPRLALSSPRPILAPLSTAGEQKRPPPHRSSKPAPTSVGQLVVSAAAGPKPPPVASVSILAPKSLGQLVISASAMPRPTPAPLGPILSPTSRDQKQLSPTSVGPKPALATSGLSLALASQEQPPQSPSSPSPVPSPVLSPSQESHLAPATVTSTPASERQLPARQKDTAVRRPIPPADGCLHTPVQAAGLATSPPRAQTSSDPRLSPSFRARPEAPRHSPEDPVLPPPPQTLPLDVSSGLPESGTRSPGLLSPTFRPGIPSNQTVPPPLPKPPRSPSRSPSRSPNRSPCVPPAPEVALPRPVTQGAGPGKCPSPNLQTQESPVATATSPTSSWSAQPTCKSDPGFRITVVTWNVGTAMPPDDVTSLLHLGGGHDSDGADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAHGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSNQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPSGGPSPSGRESHRLQVTQHSYRSHMEYTVSDHKPVAARFLLQFAFRDDVPLVRLEVADEWARPEQAVVRYRVETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEEVDGNIYQVTFSEESLPKGHGDFILGYYSHHHSILIGVTEPFQISLPTSESASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPSLALRPSSRERRGGSRSPSPQSRQLPRVAPDRGHSSGSRGSSEEGPSGPPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDQEAPDPNSLSPSPQGRLGLEDGGLGP

Target ORF information:

RefSeq Version	NM_133562.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus inositol polyphosphate-5-phosphatase J (Inpp5j), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133562.1

ORF Insert Sequence:

ATGGAGGGCC AGAGCAGGAG TGGTAGTGCC AAGTCGGGGA CCAGAACTGG ACTGGGACCC 
TTGCCTGGGA CCCATGGGGC TTTGCAAACT GGGACACCCT CGAAGAAGGT AAATTCAAGT 
TTTCAGCTTC CAGCAAAGAA CACGGGCCCA ACACCCTCAG AACCAAGATT GGCCCTGGCA 
CCGGTGGGAC CACGAGCAGC TGTGTCACCT CCTTCAGAGA GACCAAGACT GGCTTTGTCA 
TCTCCCCGAC CCATCCTAGC TCCACTGTCC ACCGCTGGCG AACAGAAAAG ACCTCCACCT 
CACCGCAGCT CCAAGCCGGC TCCCACGTCT GTGGGCCAAC TGGTAGTATC TGCCGCTGCA 
GGACCAAAGC CTCCGCCAGT CGCCTCGGTC TCAATCCTGG CTCCGAAGTC TCTGGGGCAG 
CTAGTAATAT CTGCCTCTGC TATGCCAAGG CCTACTCCGG CTCCTCTAGG GCCCATTCTA 
TCACCAACTT CCAGGGATCA GAAGCAGTTA TCACCCACCT CTGTGGGACC TAAGCCAGCA 
TTGGCAACCT CAGGCCTAAG CCTGGCACTG GCCTCTCAGG AGCAGCCCCC ACAGTCCCCC 
TCCAGTCCTT CCCCTGTGCC CAGTCCCGTT CTGTCACCCT CTCAGGAGAG TCACCTGGCT 
CCAGCAACTG TGACATCTAC CCCAGCTTCC GAGAGACAGT TGCCAGCTAG ACAGAAGGAT 
ACGGCAGTTC GCAGGCCCAT TCCCCCTGCA GACGGGTGTC TCCATACCCC AGTGCAGGCA 
GCTGGTCTTG CCACCTCTCC TCCAAGGGCC CAAACTTCCT CAGATCCTCG GCTTTCCCCC 
TCCTTCCGCG CAAGACCAGA GGCTCCGCGC CACAGTCCCG AGGATCCCGT CTTGCCGCCG 
CCACCACAGA CCCTGCCCTT GGATGTGAGC TCAGGCCTTC CAGAGTCTGG CACCCGCTCC 
CCTGGACTTC TGTCCCCTAC CTTTCGGCCA GGAATCCCTT CAAACCAGAC TGTGCCCCCA 
CCTCTGCCCA AGCCACCTCG GTCTCCCAGC CGCTCCCCTA GTCGTTCTCC CAACCGCTCT 
CCCTGTGTGC CCCCAGCCCC TGAGGTGGCA CTCCCAAGAC CTGTCACCCA GGGTGCAGGG 
CCTGGCAAGT GCCCAAGCCC TAACCTACAG ACACAAGAAA GCCCAGTCGC CACCGCCACC 
TCACCAACGT CTTCTTGGTC AGCTCAGCCT ACCTGCAAGA GCGACCCTGG ATTCCGGATC 
ACTGTGGTTA CATGGAATGT GGGCACTGCC ATGCCTCCTG ACGATGTCAC ATCTCTTCTA 
CACCTGGGTG GTGGCCACGA TAGCGACGGT GCAGACATGA TTGCCATCGG GTTGCAAGAA 
GTCAATTCCA TGATCAACAA GCGGCTCAAG GATGCTCTCT TTACCGACCA GTGGAGTGAG 
CTCTTCATGG ATGCGCTGGG GCCTTTCAAC TTCGTGCTGG TGAGCACCGT GAGGATGCAG 
GGCGTCATCC TGCTGCTCTT CGCCAAGTAC TACCACCTAC CCTTCCTACG GGATGTGCAG 
ACGGACTGTA CTCGGACTGG CCTGGGTGGC TACTGGGGTA ACAAGGGCGG AGTAAGTGTG 
CGCTTAGCAG CCTTCGGGCA CATGCTGTGC TTCCTAAACT GCCACTTGCC CGCACACATG 
GACAAGGCGG AGCAGCGCAA GGATAACTTT CAAACTATCC TTAGCCTCCA GCAATTCCAG 
GGACCTGGTG CACACGGCAT CCTGGATCAT GACCTTGTAT TCTGGTTTGG GGACCTGAAC 
TTCCGCATTG AGAGCTATGA CCTACACTTC GTCAAGTTCG CCATAGACAG CAACCAACTC 
CATCAGCTCT GGGAGAAGGA CCAGCTCAAC ATGGCCAAGA ATACTTGGCC CATCTTGAAA 
GGTTTCCAGG AAGGGCCCCT TAATTTTGCC CCCACCTTCA AGTTTGATGT GGGGACCAAC 
AAATATGATA CGAGTGCCAA GAAGCGGAAG CCAGCCTGGA CAGATCGCAT TCTGTGGAAG 
GTCAAGGCTC CAAGTGGAGG CCCCAGCCCC TCAGGGCGAG AGAGTCACAG GCTCCAGGTG 
ACCCAGCACA GCTATCGCAG TCACATGGAA TACACCGTCA GTGACCACAA GCCTGTTGCC 
GCCCGCTTCC TTCTGCAGTT TGCCTTCAGG GATGATGTAC CTCTGGTACG GCTGGAGGTG 
GCGGACGAGT GGGCAAGGCC GGAGCAGGCT GTGGTGAGAT ACCGCGTGGA AACAGTATTT 
GCCCGAAGCT CCTGGGACTG GATTGGCTTG TACCGGGTGG GTTTCCGTCA CTGTAAGGAT 
TATGTGGCTT ATGTCTGGGC CAAGCATGAA GAAGTGGATG GGAATATCTA CCAGGTGACC 
TTCAGTGAGG AGTCACTGCC CAAGGGCCAT GGCGACTTCA TCCTGGGTTA CTATAGCCAC 
CACCACAGCA TCCTCATTGG TGTCACAGAA CCCTTTCAGA TCTCGCTGCC TACCTCAGAA 
TCAGCCAGCA GCAGCACAGA CAGCTCAGGC ACCAGCTCCG AGGGGGAGGA TGACAGCACT 
CTGGAGCTGC TGGCACCCAA GTCCCGCAGC CCCAGCCCTG GCAAGTCCAA GAGACACCGT 
AGTCGCAGCC CGGGCCTAGC ACGCTTCCCC AGTCTCGCTC TCCGTCCCTC ATCCCGCGAA 
CGCCGTGGTG GCAGCCGTAG TCCCTCACCC CAGAGCCGCC AGCTGCCTCG GGTAGCCCCC 
GACAGGGGTC ACAGTAGTGG CAGCCGAGGT AGTAGTGAGG AGGGGCCCTC TGGGCCGCCT 
GGACCCTGGG CCTTCCCACC AGCTGTGCCT CGAAGCCTGG GCCTGCTTCC AGCCTTGCGC 
CTGGAGACCG TAGACCCAGG TGGCGGAGGC TCCTGGGGAC CTGACCAGGA GGCCCCTGAC 
CCTAATAGCC TGTCCCCCAG CCCGCAGGGC AGGCTGGGGC TAGAGGACGG GGGTTTGGGG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)?collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.
The Journal of biological chemistry286(26)23407-18(2011 Jul)
Astle MV,Ooms LM,Cole AR,Binge LC,Dyson JM,Layton MJ,Petratos S,Sutherland C,Mitchell CA

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
Molecular biology of the cell17(2)607-22(2006 Feb)
Ooms LM,Fedele CG,Astle MV,Ivetac I,Cheung V,Pearson RB,Layton MJ,Forrai A,Nandurkar HH,Mitchell CA

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.
The Journal of biological chemistry278(13)11376-85(2003 Mar)
Gurung R,Tan A,Ooms LM,McGrath MJ,Huysmans RD,Munday AD,Prescott M,Whisstock JC,Mitchell CA

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.
The Journal of biological chemistry277(25)22734-42(2002 Jun)
Woodcock EA,Wang BH,Arthur JF,Lennard A,Matkovich SJ,Du XJ,Brown JH,Hannan RD

Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy.
Journal of molecular biology315(4)677-85(2002 Jan)
Patel S,Yenush L,Rodr?guez PL,Serrano R,Blundell TL

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Inpp5j cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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