Slc17a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc17a1
Entrez Gene ID	171080
Full Name	solute carrier family 17 member 1
Synonyms	Napi-1
General protein information	Preferred Names solute carrier family 17 member 1 Names sodium-dependent phosphate transport protein 1 Na(+)/PI cotransporter 1 renal Na(+)-dependent phosphate cotransporter 1 renal sodium-dependent phosphate transport protein 1 renal sodium-phosphate transport protein 1 sodium/phosphate cotransporter 1 solute carrier family 17 (organic anion transporter), member 1 solute carrier family 17 (sodium phosphate), member 1 solute carrier family 17 vesicular glutamate transporter), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p11
Summary	cotransports sodium and phosphate [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133554.2	NP_598238.2	sodium-dependent phosphate transport protein 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc17a1	NP_598238.2
Pan troglodytes (chimpanzee)	SLC17A1	XP_518283.3
	SLC17A1	XP_002803705.1
Canis lupus familiaris (dog)	SLC17A1	XP_005640161.1
Bos taurus (cattle)	SLC17A1	XP_005223872.1
Mus musculus (house mouse)	Slc17a1	NP_001164109.1
Homo sapiens (human)	SLC17A1	NP_005065.2

Gene Ontology
Bibliography

Related articles in PubMed

Expression of a human NPT1/SLC17A1 missense variant which increases urate export.
Sakiyama M, Matsuo H, Nagamori S, Ling W, Kawamura Y, Nakayama A, Higashino T, Chiba T, Ichida K, Kanai Y, Shinomiya N
Nucleosides, nucleotides & nucleic acids35(10-12)536-542(2016 Dec)

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H, , Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI, , Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani NJ, Schlessinger D, Uda M, V?lker U, Waeber G, Waterworth D, Wang-Sattler R, Wright AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H, , Doering A, Wichmann HE, , Spector TD, Peltonen L, V?lzke H, Nagaraja R, Vollenweider P, Caulfield M, , Illig T, Gieger C
PLoS genetics5(6)e1000504(2009 Jun)

Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes.
Hinojos CA, Boerwinkle E, Fornage M, Doris PA
Hypertension (Dallas, Tex. : 1979)45(4)698-704(2005 Apr)

Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses.
Alvarez FJ, Villalba RM, Zerda R, Schneider SP
The Journal of comparative neurology472(3)257-80(2004 May)

Expression of vesicular glutamate transporters in rat lumbar spinal cord, with a note on dorsal root ganglia.
Landry M, Bouali-Benazzouz R, El Mestikawy S, Ravassard P, Nagy F
The Journal of comparative neurology468(3)380-94(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

VGLUT1 localization (most abundant in LIII/LIV and medial LV of sponal cord) is consistent with an origin from cutaneous and muscle mechanoreceptors and disappeared after rhizotomy.
Title: Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses.

A high density of VGluT1-immunoreactive fibers is present in gracilis and cuneatus nuclei, a moderate density in lateral and interstitial subnuclei, and a low density in dorsolateral, ventral and intermediate subnuclei of the nucleus tractus solitarii.
Title: Localization of vesicular glutamate transporters and neuronal nitric oxide synthase in rat nucleus tractus solitarii.

VGLUT1 and VGLUT2 transcripts are colocalized in most sensory neurons of the dorsal root ganglia, as well as in motor neurons of the ventral horn.
Title: Expression of vesicular glutamate transporters in rat lumbar spinal cord, with a note on dorsal root ganglia.

More than 80% of trigeminal ganglion neurons express vesicular glutamate transporter (VGluT)1 and VGluT2. VGluT1 is coexpressed with VGluT2 in the cell bodies and axon terminals in most trigeminal ganglion neurons.
Title: Vesicular glutamate transporters, VGluT1 and VGluT2, in the trigeminal ganglion neurons of the rat, with special reference to coexpression.

In the cerebellar granular layer, vesicular glutamate transporter 1 (Slc17a1) immunoreactivity is found in mossy fiber terminals and in single-axon terminals and in most brainstem precerebellar nuclei sending mossy fibers.
Title: Differential distribution of vesicular glutamate transporters in the rat cerebellar cortex.

The following Slc17a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc17a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00922	NM_133554.2 Latest version!	Rattus norvegicus solute carrier family 17 member 1 (Slc17a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$272.30 $389.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc17a1 ( NM_133554.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598238.2 Rattus norvegicus solute carrier family 17 member 1 (Slc17a1), mRNA.

Price & Availability↑

CloneID	ORa00922
Clone ID Related Accession (Same CDS sequence)	NM_133554.2
Accession Version	NM_133554.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1398bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	sodium-dependent phosphate transport protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078748.1. On Aug 8, 2004 this sequence version replaced NM_133554.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078748.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689597, SAMEA2689598 [ECO:0000350] ##Evidence-Data-END##

ATGGAGAACC GGTGCCTCCC CAAGAAAGTT CCAGGTTTCT GTTCCTTTCG GTATGGACTG 
GCTATCCTTT TGCACTTCTG TAACATTGTC ATCATGGCTC AGCGAGTGTG CCTGAACCTC 
ACAATGGTAG CCATGGTGAA TAAAACAGAG CCACCCCATT TATCTAACAA GTCTGTAGCA 
GAGATGCTGG ATAATGTAAA GAACCCTGTG CATTCCTGGA GTCTTGATAT TCAAGGGCTT 
ATTCTCAGTT CTGTCTTCTT GGGTATGGTT GTGATTCAAG TTCCTGTTGG GTACCTATCT 
GGAGCATACC CAATGAAGAA AATAATTGGG TCTTCATTGT TCCTCAGCTC TGTGCTGTCC 
CTGCTCATCC CACCAGCTGC ACAAGTCGGA GCAGCTTTGG TCATTGTATG CCGAGTACTC 
CAAGGAATAG CCCAGGGAGC AGTGTCAACA GGCCAGCATG GAATATGGGT CAAATGGGCA 
CCTCCCTTGG AACGAGGCAG ACTTACCTCT ATGACTCTAT CAGGGTTTGT AATGGGACCA 
TTTATTGCCC TGCTTGTGAG TGGCTTCATC TGTGATCTTC TGGGTTGGCC CATGGTTTTC 
TACATCTTTG GTATTGTTGG GTGTGTTCTG AGTCTTTTCT GGTTCATCCT TTTCTTTGAT 
GACCCCAACA ACCACCCATA TATGAGCAGC AGTGAGAAGG ATTACATCAC ATCCTCTCTC 
ATGCAACAGG TGCACTCGGG CAGACAATCT CTGCCAATCA AAGCTATGCT TAAGTCTCTT 
CCACTCTGGG CCATTATCCT CAATAGCTTT GCTTTCATAT GGTCGAACAA TCTTCTGGTT 
ACATACACGC CAACATTTAT TAGCACCACG CTTCATGTTA ATGTTAGAGA GAATGGGCTG 
CTGTCCAGCC TCCCCTATCT GCTTGCCTAC ATCTGTGGTA TCGTAGCAGG TCAGATGTCA 
GACTTCCTCC TGTCAAGGAA GATTTTCAGC GTAGTTGCTG TCCGGAAACT CTTCACCACA 
CTAGGGATTT TCTGTCCTGT GATTTTTGTC GTGTGCCTGC TCTACCTGAG CTACAACTTC 
TACAGCACCG TCATTTTCCT TACACTTGCC AACTCGACAC TTAGCTTTTC CTTCTGTGGA 
CAACTTATCA ATGCCTTGGA TATTGCTCCC AGATATTATG GATTTCTAAA GGCAGTCACA 
GCTTTAATTG GAATATTTGG GGGCCTAATT TCTTCAACTC TTGCTGGGTT GATCCTTAAT 
CAGGATCCAG AATATGCTTG GCATAAAAAC TTCTTCTTGA TGGCAGGCAT TAACGTGACA 
TGCCTGGCTT TCTACCTTCT GTTTGCAAAA GGAGATATTC AGGACTGGGC TAAAGAAACA 
AAAACCACAC GGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598238.2
CDS	145..1542
Translation	MENRCLPKKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGAALVIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICDLLGWPMVFYIFGIVGCVLSLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSFSFCGQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQDWAKETKTTRL

Target ORF information:

RefSeq Version	NM_133554.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 17 member 1 (Slc17a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133554.2

ORF Insert Sequence:

ATGGAGAACC GGTGCCTCCC CAAGAAAGTT CCAGGTTTCT GTTCCTTTCG GTATGGACTG 
GCTATCCTTT TGCACTTCTG TAACATTGTC ATCATGGCTC AGCGAGTGTG CCTGAACCTC 
ACAATGGTAG CCATGGTGAA TAAAACAGAG CCACCCCATT TATCTAACAA GTCTGTAGCA 
GAGATGCTGG ATAATGTAAA GAACCCTGTG CATTCCTGGA GTCTTGATAT TCAAGGGCTT 
ATTCTCAGTT CTGTCTTCTT GGGTATGGTT GTGATTCAAG TTCCTGTTGG GTACCTATCT 
GGAGCATACC CAATGAAGAA AATAATTGGG TCTTCATTGT TCCTCAGCTC TGTGCTGTCC 
CTGCTCATCC CACCAGCTGC ACAAGTCGGA GCAGCTTTGG TCATTGTATG CCGAGTACTC 
CAAGGAATAG CCCAGGGAGC AGTGTCAACA GGCCAGCATG GAATATGGGT CAAATGGGCA 
CCTCCCTTGG AACGAGGCAG ACTTACCTCT ATGACTCTAT CAGGGTTTGT AATGGGACCA 
TTTATTGCCC TGCTTGTGAG TGGCTTCATC TGTGATCTTC TGGGTTGGCC CATGGTTTTC 
TACATCTTTG GTATTGTTGG GTGTGTTCTG AGTCTTTTCT GGTTCATCCT TTTCTTTGAT 
GACCCCAACA ACCACCCATA TATGAGCAGC AGTGAGAAGG ATTACATCAC ATCCTCTCTC 
ATGCAACAGG TGCACTCGGG CAGACAATCT CTGCCAATCA AAGCTATGCT TAAGTCTCTT 
CCACTCTGGG CCATTATCCT CAATAGCTTT GCTTTCATAT GGTCGAACAA TCTTCTGGTT 
ACATACACGC CAACATTTAT TAGCACCACG CTTCATGTTA ATGTTAGAGA GAATGGGCTG 
CTGTCCAGCC TCCCCTATCT GCTTGCCTAC ATCTGTGGTA TCGTAGCAGG TCAGATGTCA 
GACTTCCTCC TGTCAAGGAA GATTTTCAGC GTAGTTGCTG TCCGGAAACT CTTCACCACA 
CTAGGGATTT TCTGTCCTGT GATTTTTGTC GTGTGCCTGC TCTACCTGAG CTACAACTTC 
TACAGCACCG TCATTTTCCT TACACTTGCC AACTCGACAC TTAGCTTTTC CTTCTGTGGA 
CAACTTATCA ATGCCTTGGA TATTGCTCCC AGATATTATG GATTTCTAAA GGCAGTCACA 
GCTTTAATTG GAATATTTGG GGGCCTAATT TCTTCAACTC TTGCTGGGTT GATCCTTAAT 
CAGGATCCAG AATATGCTTG GCATAAAAAC TTCTTCTTGA TGGCAGGCAT TAACGTGACA 
TGCCTGGCTT TCTACCTTCT GTTTGCAAAA GGAGATATTC AGGACTGGGC TAAAGAAACA 
AAAACCACAC GGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of a human NPT1/SLC17A1 missense variant which increases urate export.
Nucleosides, nucleotides & nucleic acids35(10-12)536-542(2016 Dec)
Sakiyama M,Matsuo H,Nagamori S,Ling W,Kawamura Y,Nakayama A,Higashino T,Chiba T,Ichida K,Kanai Y,Shinomiya N

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
PLoS genetics5(6)e1000504(2009 Jun)
Kolz M,Johnson T,Sanna S,Teumer A,Vitart V,Perola M,Mangino M,Albrecht E,Wallace C,Farrall M,Johansson A,Nyholt DR,Aulchenko Y,Beckmann JS,Bergmann S,Bochud M,Brown M,Campbell H,,Connell J,Dominiczak A,Homuth G,Lamina C,McCarthy MI,,Meitinger T,Mooser V,Munroe P,Nauck M,Peden J,Prokisch H,Salo P,Salomaa V,Samani NJ,Schlessinger D,Uda M,V?lker U,Waeber G,Waterworth D,Wang-Sattler R,Wright AF,Adamski J,Whitfield JB,Gyllensten U,Wilson JF,Rudan I,Pramstaller P,Watkins H,,Doering A,Wichmann HE,,Spector TD,Peltonen L,V?lzke H,Nagaraja R,Vollenweider P,Caulfield M,,Illig T,Gieger C

Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes.
Hypertension (Dallas, Tex. : 1979)45(4)698-704(2005 Apr)
Hinojos CA,Boerwinkle E,Fornage M,Doris PA

Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses.
The Journal of comparative neurology472(3)257-80(2004 May)
Alvarez FJ,Villalba RM,Zerda R,Schneider SP

Expression of vesicular glutamate transporters in rat lumbar spinal cord, with a note on dorsal root ganglia.
The Journal of comparative neurology468(3)380-94(2004 Jan)
Landry M,Bouali-Benazzouz R,El Mestikawy S,Ravassard P,Nagy F

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Slc17a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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