A1cf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	A1cf
Entrez Gene ID	170912
Full Name	APOBEC1 complementation factor
Synonyms	A1cft,Acf,Apobec-1
General protein information	Preferred Names APOBEC1 complementation factor Names APOBEC1 complementation factor APOBEC1 complementation factort APOBEC1-stimulating protein Apobec-1 complementation factor, APOBEC-1 stimulating protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q52
Summary	complementation factor that binds to RNA in a heterochromatin-associated protein complex that edits cytidine to uridine [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133400.1	NP_596891.1	APOBEC1 complementation factor
XM_006231272.3	XP_006231334.1	APOBEC1 complementation factor isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	A1CF	XP_861026.1
Mus musculus (house mouse)	A1cf	NP_001074543.1
Gallus gallus (chicken)	A1CF	XP_421561.3
Danio rerio (zebrafish)	a1cf	XP_685178.1
Pan troglodytes (chimpanzee)	A1CF	XP_001162562.2
Rattus norvegicus (Norway rat)	A1cf	NP_596891.1
Homo sapiens (human)	A1CF	NP_055391.2
Bos taurus (cattle)	A1CF	XP_005225432.1
Xenopus tropicalis (tropical clawed frog)	a1cf	XP_002935470.2
	A1CF	XP_001100059.1

Gene Ontology
Bibliography

Related articles in PubMed

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.
Rasheed H, Stamp LK, Dalbeth N, Merriman TR
Arthritis research & therapy19(1)161(2017 Jul)

Effects of multiple genetic loci on the pathogenesis from serum urate to gout.
Dong Z, Zhou J, Jiang S, Li Y, Zhao D, Yang C, Ma Y, Wang Y, He H, Ji H, Yang Y, Wang X, Xu X, Pang Y, Zou H, Jin L, Wang J
Scientific reports743614(2017 Mar)

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.
Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert JB, Power M, Jones V, Loebel DA, Tam PP
EMBO reports15(8)903-10(2014 Aug)

Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.
Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC
Biochimica et biophysica acta1802(11)976-85(2010 Nov)

APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.
Galloway CA, Kumar A, Krucinska J, Smith HC
Biochemical and biophysical research communications398(1)38-43(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

N-terminal 320 amino acids of ACF retained RNA-binding selectivity and supported complementation of editing activity and in addition demonstrate a novel RNA-bridged multimerization of ACF.
Title: APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.

phosphorylation of ACF by protein kinase C may be a key regulatory mechanism of apoB mRNA editing in rat hepatocytes
Title: Functional characterization of APOBEC-1 complementation factor phosphorylation sites.

ACF plays a crucial role, which is independent of apobec-1 expression, in cell survival, particularly during early embryonic development
Title: Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality.

Splice variants of this protein are associated with different capacities to support apoB mrna editing.
Title: Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing.

role in in vitro deamination of cytosine to uracil in single-stranded DNA
Title: In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1).

The following A1cf gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the A1cf cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00692	NM_133400.1 Latest version!	Rattus norvegicus APOBEC1 complementation factor (A1cf), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa24027	XM_006231272.3 Latest version!	Rattus norvegicus APOBEC1 complementation factor (A1cf), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

A1cf ( NM_133400.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_596891.1 Rattus norvegicus APOBEC1 complementation factor (A1cf), mRNA.

Price & Availability↑

CloneID	ORa00692
Clone ID Related Accession (Same CDS sequence)	NM_133400.1
Accession Version	NM_133400.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	APOBEC1 complementation factor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF290984.1. On Dec 17, 2003 this sequence version replaced XM_346579.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF290984.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END##

ATGGAATCAA ATCACAAATC CGGGGATGGA TTGAGCGGCA CCCAGAAGGA AGCAGCACTC 
CGCGCACTGG TCCAGCGCAC AGGATATAGC TTGGTCCAGG AAAATGGACA AAGAAAATAT 
GGTGGTCCTC CACCAGGCTG GGATACTACA CCCCCAGAAA GGGGCTGCGA GATTTTCATT 
GGGAAACTTC CCCGGGACCT TTTTGAGGAT GAACTCATAC CATTGTGTGA AAAAATTGGT 
AAAATTTATG AAATGAGAAT GATGATGGAT TTCAATGGGA ACAACAGAGG CTATGCATTT 
GTAACCTTCT CAAATAAGCA GGAAGCCAAG AATGCAATCA AGCAACTTAA TAATTATGAA 
ATTCGGAATG GCCGTCTCCT GGGCGTCTGT GCCAGTGTGG ACAACTGCCG GTTGTTTGTG 
GGGGGAATCC CCAAAACCAA AAAGAGAGAA GAAATCTTGT CAGAGATGAA AAAGGTCACT 
GAAGGAGTTG TTGATGTCAT TGTCTACCCA AGCGCTGCCG ATAAAACCAA AAACCGGGGG 
TTTGCCTTTG TGGAATATGA GAGTCACCGC GCAGCCGCCA TGGCTAGGCG GAGGCTGCTG 
CCAGGAAGAA TTCAGTTGTG GGGACATCCT ATCGCAGTAG ACTGGGCAGA GCCAGAAGTC 
GAAGTTGACG AAGACACAAT GTCTTCCGTG AAAATCCTGT ACGTAAGGAA CCTTATGCTG 
TCTACCTCGG AAGAGATGAT TGAGAAGGAA TTCAACAGTA TTAAACCAGG TGCTGTGGAA 
CGGGTGAAGA AGATCCGAGA CTATGCTTTT GTGCATTTCA GTAACCGAGA AGATGCAGTT 
GAAGCCATGA AGGCTTTGAA TGGCAAGGTG CTGGATGGTT CCCCAATAGA AGTGACCTTG 
GCCAAGCCAG TGGACAAGGA CAGTTACGTT AGGTACACCC GGGGCACCGG GGGCAGGAAC 
ACCATGCTGC AAGAATACAC CTACCCTCTG AGCCATGTTT ATGACCCTAC CACAACCTAC 
CTTGGAGCTC CTGTCTTCTA TACTCCCCAA GCCTACGCAG CCATTCCAAG TCTTCATTTC 
CCAGCTACCA AAGGACATCT CAGCAACAGA GCTCTCATCC GGACCCCTTC TGTCAGAGGG 
GCTGCGGGCG TGAGAGGACT GGGCGGCCGT GGGTATTTGG CATATACAGG CCTGGGTCGA 
GGATACCAGG TCAAAGGAGA CAAGAGACAA GACAAACTCT ATGACCTTCT GCCTGGGATG 
GAGCTCACCC CGATGAATAC TATCTCTTTA AAACCACAAG GAGTTAAACT TGCTCCTCAG 
ATATTAGAAG AAATCTGTCA GAAAAATAAC TGGGGACAGC CAGTGTACCA GCTGCACTCT 
GCCATTGGAC AAGACCAAAG ACAGTTATTC CTATACAAAG TAACTATCCC AGCGCTGGCC 
AGCCAGAATC CTGCGATCCA CCCTTTCACA CCCCCAAAGC TAAGCGCCTA CGTGGATGAA 
GCAAAGAGGT ACGCCGCAGA GCACACCCTA CAGACACTAG GCATCCCCAC AGAAGGAGGG 
GACGCTGGGA CTACAGCACC CACTGCCACA TCCGCCACTG TGTTTCCAGG ATACGCTGTC 
CCCAGTGCCA CCGCTCCTGT GTCTACAGCC CAGCTCAAGC AAGCAGTGAC ACTTGGACAA 
GACTTAGCAG CATATACAAC CTATGAGGTC TACCCTACTT TTGCAGTGAC CACCCGAGGT 
GATGGATATG GCACCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_596891.1
CDS	103..1863
Translation	MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDTTPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKQEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRRLLPGRIQLWGHPIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNSIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRNTMLQEYTYPLSHVYDPTTTYLGAPVFYTPQAYAAIPSLHFPATKGHLSNRALIRTPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRQDKLYDLLPGMELTPMNTISLKPQGVKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKVTIPALASQNPAIHPFTPPKLSAYVDEAKRYAAEHTLQTLGIPTEGGDAGTTAPTATSATVFPGYAVPSATAPVSTAQLKQAVTLGQDLAAYTTYEVYPTFAVTTRGDGYGTF

Target ORF information:

RefSeq Version	NM_133400.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus APOBEC1 complementation factor (A1cf), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133400.1

ORF Insert Sequence:

ATGGAATCAA ATCACAAATC CGGGGATGGA TTGAGCGGCA CCCAGAAGGA AGCAGCACTC 
CGCGCACTGG TCCAGCGCAC AGGATATAGC TTGGTCCAGG AAAATGGACA AAGAAAATAT 
GGTGGTCCTC CACCAGGCTG GGATACTACA CCCCCAGAAA GGGGCTGCGA GATTTTCATT 
GGGAAACTTC CCCGGGACCT TTTTGAGGAT GAACTCATAC CATTGTGTGA AAAAATTGGT 
AAAATTTATG AAATGAGAAT GATGATGGAT TTCAATGGGA ACAACAGAGG CTATGCATTT 
GTAACCTTCT CAAATAAGCA GGAAGCCAAG AATGCAATCA AGCAACTTAA TAATTATGAA 
ATTCGGAATG GCCGTCTCCT GGGCGTCTGT GCCAGTGTGG ACAACTGCCG GTTGTTTGTG 
GGGGGAATCC CCAAAACCAA AAAGAGAGAA GAAATCTTGT CAGAGATGAA AAAGGTCACT 
GAAGGAGTTG TTGATGTCAT TGTCTACCCA AGCGCTGCCG ATAAAACCAA AAACCGGGGG 
TTTGCCTTTG TGGAATATGA GAGTCACCGC GCAGCCGCCA TGGCTAGGCG GAGGCTGCTG 
CCAGGAAGAA TTCAGTTGTG GGGACATCCT ATCGCAGTAG ACTGGGCAGA GCCAGAAGTC 
GAAGTTGACG AAGACACAAT GTCTTCCGTG AAAATCCTGT ACGTAAGGAA CCTTATGCTG 
TCTACCTCGG AAGAGATGAT TGAGAAGGAA TTCAACAGTA TTAAACCAGG TGCTGTGGAA 
CGGGTGAAGA AGATCCGAGA CTATGCTTTT GTGCATTTCA GTAACCGAGA AGATGCAGTT 
GAAGCCATGA AGGCTTTGAA TGGCAAGGTG CTGGATGGTT CCCCAATAGA AGTGACCTTG 
GCCAAGCCAG TGGACAAGGA CAGTTACGTT AGGTACACCC GGGGCACCGG GGGCAGGAAC 
ACCATGCTGC AAGAATACAC CTACCCTCTG AGCCATGTTT ATGACCCTAC CACAACCTAC 
CTTGGAGCTC CTGTCTTCTA TACTCCCCAA GCCTACGCAG CCATTCCAAG TCTTCATTTC 
CCAGCTACCA AAGGACATCT CAGCAACAGA GCTCTCATCC GGACCCCTTC TGTCAGAGGG 
GCTGCGGGCG TGAGAGGACT GGGCGGCCGT GGGTATTTGG CATATACAGG CCTGGGTCGA 
GGATACCAGG TCAAAGGAGA CAAGAGACAA GACAAACTCT ATGACCTTCT GCCTGGGATG 
GAGCTCACCC CGATGAATAC TATCTCTTTA AAACCACAAG GAGTTAAACT TGCTCCTCAG 
ATATTAGAAG AAATCTGTCA GAAAAATAAC TGGGGACAGC CAGTGTACCA GCTGCACTCT 
GCCATTGGAC AAGACCAAAG ACAGTTATTC CTATACAAAG TAACTATCCC AGCGCTGGCC 
AGCCAGAATC CTGCGATCCA CCCTTTCACA CCCCCAAAGC TAAGCGCCTA CGTGGATGAA 
GCAAAGAGGT ACGCCGCAGA GCACACCCTA CAGACACTAG GCATCCCCAC AGAAGGAGGG 
GACGCTGGGA CTACAGCACC CACTGCCACA TCCGCCACTG TGTTTCCAGG ATACGCTGTC 
CCCAGTGCCA CCGCTCCTGT GTCTACAGCC CAGCTCAAGC AAGCAGTGAC ACTTGGACAA 
GACTTAGCAG CATATACAAC CTATGAGGTC TACCCTACTT TTGCAGTGAC CACCCGAGGT 
GATGGATATG GCACCTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A1cf ( XM_006231272.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231334.1 Rattus norvegicus APOBEC1 complementation factor (A1cf), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24027
Clone ID Related Accession (Same CDS sequence)	XM_006231272.3
Accession Version	XM_006231272.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1785bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	APOBEC1 complementation factor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231272.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCAA ATCACAAATC CGGGGATGGA TTGAGCGGCA CCCAGAAGGA AGCAGCACTC 
CGCGCACTGG TCCAGCGCAC AGGATATAGC TTGGTCCAGG AAAATGGACA AAGAAAATAT 
GGTGGTCCTC CACCAGGATG GGATACTACA CCCCCAGAAA GGGGCTGCGA GATTTTCATT 
GGGAAACTTC CCCGGGACCT TTTTGAGGAT GAACTCATAC CATTGTGTGA AAAAATTGGT 
AAAATTTATG AAATGAGAAT GATGATGGAT TTCAATGGGA ACAACAGAGG CTATGCATTT 
GTAACCTTCT CAAATAAGCA GGAAGCCAAG AATGCAATCA AGCAACTTAA TAATTATGAA 
ATTCGGAATG GCCGTCTCCT GGGCGTCTGT GCCAGTGTGG ACAACTGCCG GTTGTTTGTG 
GGGGGAATCC CCAAAACCAA AAAGAGAGAA GAAATCTTGT CAGAGATGAA AAAGGTCACT 
GAAGGAGTTG TTGATGTCAT TGTCTACCCA AGCGCTGCCG ATAAAACCAA AAACCGGGGG 
TTTGCCTTTG TGGAATATGA GAGTCACCGC GCAGCCGCCA TGGCTAGGCG GAGGCTGCTG 
CCAGGAAGAA TTCAGTTGTG GGGACATCCT ATCGCAGTAG ACTGGGCAGA GCCAGAAGTC 
GAAGTTGACG AAGACACAAT GTCTTCCGTG AAAATCCTGT ACGTAAGGAA CCTTATGCTG 
TCTACCTCGG AAGAGATGAT TGAGAAGGAA TTCAACAGTA TTAAACCAGG TGCTGTGGAA 
CGGGTGAAGA AGATCCGAGA CTATGCTTTT GTGCATTTCA GTAACCGAGA AGATGCAGTT 
GAAGCCATGA AGGCTTTGAA TGGCAAGGTG CTGGATGGTT CCCCAATAGA AGTGACCTTG 
GCCAAGCCAG TGGACAAGGA CAGTTACGTT AGGTACACCC GGGGCACCGG GGGCAGGAAC 
ACCATGCTGC AAGAATACAC CTACCCTCTG AGCCATGTTT ATGACCCTAC CACAACCTAC 
CTTGGAGCTC CTGTCTTCTA TACTCCCCAA GCCTACGCAG CCATTCCAAG TCTTCATTTC 
CCAGCTACCA AAGGACATCT CAGCAACAGA GCTCTCATCC GGACCCCTTC TGTCAGAGAA 
ATTTACATGA ATGTCCCTGT AGGGGCTGCG GGCGTGAGAG GACTGGGCGG CCGTGGGTAT 
TTGGCATATA CAGGCCTGGG TCGAGGATAC CAGGTCAAAG GAGACAAGAG ACAAGACAAA 
CTCTATGACC TTCTGCCTGG GATGGAGCTC ACCCCGATGA ATACTATCTC TTTAAAACCA 
CAAGGAGTTA AACTTGCTCC TCAGATATTA GAAGAAATCT GTCAGAAAAA TAACTGGGGA 
CAGCCAGTGT ACCAGCTGCA CTCTGCCATT GGACAAGACC AAAGACAGTT ATTCCTATAC 
AAAGTAACTA TCCCAGCGCT GGCCAGCCAG AATCCTGCGA TCCACCCTTT CACACCCCCA 
AAGCTAAGCG CCTACGTGGA TGAAGCAAAG AGGTACGCCG CAGAGCACAC CCTACAGACA 
CTAGGCATCC CCACAGAAGG AGGGGACGCT GGGACTACAG CACCCACTGC CACATCCGCC 
ACTGTGTTTC CAGGATACGC TGTCCCCAGT GCCACCGCTC CTGTGTCTAC AGCCCAGCTC 
AAGCAAGCAG TGACACTTGG ACAAGACTTA GCAGCATATA CAACCTATGA GGTCTACCCT 
ACTTTTGCAG TGACCACCCG AGGTGATGCA TATGGCGCCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231334.1
CDS	268..2052
Translation	MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDTTPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKQEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRRLLPGRIQLWGHPIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNSIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRNTMLQEYTYPLSHVYDPTTTYLGAPVFYTPQAYAAIPSLHFPATKGHLSNRALIRTPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRQDKLYDLLPGMELTPMNTISLKPQGVKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKVTIPALASQNPAIHPFTPPKLSAYVDEAKRYAAEHTLQTLGIPTEGGDAGTTAPTATSATVFPGYAVPSATAPVSTAQLKQAVTLGQDLAAYTTYEVYPTFAVTTRGDAYGAF

Target ORF information:

RefSeq Version	XM_006231272.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus APOBEC1 complementation factor (A1cf), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231272.3

ORF Insert Sequence:

ATGGAATCAA ATCACAAATC CGGGGATGGA TTGAGCGGCA CCCAGAAGGA AGCAGCACTC 
CGCGCACTGG TCCAGCGCAC AGGATATAGC TTGGTCCAGG AAAATGGACA AAGAAAATAT 
GGTGGTCCTC CACCAGGATG GGATACTACA CCCCCAGAAA GGGGCTGCGA GATTTTCATT 
GGGAAACTTC CCCGGGACCT TTTTGAGGAT GAACTCATAC CATTGTGTGA AAAAATTGGT 
AAAATTTATG AAATGAGAAT GATGATGGAT TTCAATGGGA ACAACAGAGG CTATGCATTT 
GTAACCTTCT CAAATAAGCA GGAAGCCAAG AATGCAATCA AGCAACTTAA TAATTATGAA 
ATTCGGAATG GCCGTCTCCT GGGCGTCTGT GCCAGTGTGG ACAACTGCCG GTTGTTTGTG 
GGGGGAATCC CCAAAACCAA AAAGAGAGAA GAAATCTTGT CAGAGATGAA AAAGGTCACT 
GAAGGAGTTG TTGATGTCAT TGTCTACCCA AGCGCTGCCG ATAAAACCAA AAACCGGGGG 
TTTGCCTTTG TGGAATATGA GAGTCACCGC GCAGCCGCCA TGGCTAGGCG GAGGCTGCTG 
CCAGGAAGAA TTCAGTTGTG GGGACATCCT ATCGCAGTAG ACTGGGCAGA GCCAGAAGTC 
GAAGTTGACG AAGACACAAT GTCTTCCGTG AAAATCCTGT ACGTAAGGAA CCTTATGCTG 
TCTACCTCGG AAGAGATGAT TGAGAAGGAA TTCAACAGTA TTAAACCAGG TGCTGTGGAA 
CGGGTGAAGA AGATCCGAGA CTATGCTTTT GTGCATTTCA GTAACCGAGA AGATGCAGTT 
GAAGCCATGA AGGCTTTGAA TGGCAAGGTG CTGGATGGTT CCCCAATAGA AGTGACCTTG 
GCCAAGCCAG TGGACAAGGA CAGTTACGTT AGGTACACCC GGGGCACCGG GGGCAGGAAC 
ACCATGCTGC AAGAATACAC CTACCCTCTG AGCCATGTTT ATGACCCTAC CACAACCTAC 
CTTGGAGCTC CTGTCTTCTA TACTCCCCAA GCCTACGCAG CCATTCCAAG TCTTCATTTC 
CCAGCTACCA AAGGACATCT CAGCAACAGA GCTCTCATCC GGACCCCTTC TGTCAGAGAA 
ATTTACATGA ATGTCCCTGT AGGGGCTGCG GGCGTGAGAG GACTGGGCGG CCGTGGGTAT 
TTGGCATATA CAGGCCTGGG TCGAGGATAC CAGGTCAAAG GAGACAAGAG ACAAGACAAA 
CTCTATGACC TTCTGCCTGG GATGGAGCTC ACCCCGATGA ATACTATCTC TTTAAAACCA 
CAAGGAGTTA AACTTGCTCC TCAGATATTA GAAGAAATCT GTCAGAAAAA TAACTGGGGA 
CAGCCAGTGT ACCAGCTGCA CTCTGCCATT GGACAAGACC AAAGACAGTT ATTCCTATAC 
AAAGTAACTA TCCCAGCGCT GGCCAGCCAG AATCCTGCGA TCCACCCTTT CACACCCCCA 
AAGCTAAGCG CCTACGTGGA TGAAGCAAAG AGGTACGCCG CAGAGCACAC CCTACAGACA 
CTAGGCATCC CCACAGAAGG AGGGGACGCT GGGACTACAG CACCCACTGC CACATCCGCC 
ACTGTGTTTC CAGGATACGC TGTCCCCAGT GCCACCGCTC CTGTGTCTAC AGCCCAGCTC 
AAGCAAGCAG TGACACTTGG ACAAGACTTA GCAGCATATA CAACCTATGA GGTCTACCCT 
ACTTTTGCAG TGACCACCCG AGGTGATGCA TATGGCGCCT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.
Arthritis research & therapy19(1)161(2017 Jul)
Rasheed H,Stamp LK,Dalbeth N,Merriman TR

Effects of multiple genetic loci on the pathogenesis from serum urate to gout.
Scientific reports743614(2017 Mar)
Dong Z,Zhou J,Jiang S,Li Y,Zhao D,Yang C,Ma Y,Wang Y,He H,Ji H,Yang Y,Wang X,Xu X,Pang Y,Zou H,Jin L,Wang J

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.
EMBO reports15(8)903-10(2014 Aug)
Fossat N,Tourle K,Radziewic T,Barratt K,Liebhold D,Studdert JB,Power M,Jones V,Loebel DA,Tam PP

Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.
Biochimica et biophysica acta1802(11)976-85(2010 Nov)
Galloway CA,Ashton J,Sparks JD,Mooney RA,Smith HC

APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.
Biochemical and biophysical research communications398(1)38-43(2010 Jul)
Galloway CA,Kumar A,Krucinska J,Smith HC

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A1cf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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