gRNAs
The following Pde11a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pde11a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01647 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001127481.2 | |
| Accession Version | NM_001127481.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1746bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-03 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB059360.1. On Aug 31, 2012 this sequence version replaced NM_001127481.1. ##Evidence-Data-START## Transcript exon combination :: AB059360.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGAGCTGGG TTATGCAGAT GTATCTTCCA TTCTGTGGCA TCGCCATATC TAATGCTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001120953.1 |
| CDS | 157..1902 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001127481.2 |
1 | ATGAGCTGGG TTATGCAGAT GTATCTTCCA TTCTGTGGCA TCGCCATATC TAATGCTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa00252 | |
| Clone ID Related Accession (Same CDS sequence) | NM_080893.1 | |
| Accession Version | NM_080893.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2808bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-03 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB059362.1. Transcript Variant: This variant (4), also known as PDE11A4, represents the longest transcript and encodes the longest protein (isoform 4). ##Evidence-Data-START## Transcript exon combination :: AB059362.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_543169.1 |
| CDS | 169..2976 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_080893.1 |
1 | ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa01644 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001127480.1 | |
| Accession Version | NM_001127480.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-03 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 3 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB059361.1. Transcript Variant: This variant (3), also known as PDE11A3, contains a distinct 5' UTR and 5' coding region, compared to variant 4. The resulting isoform (3) contains a shorter and distinct N-terminus, compared to isoform 4. ##Evidence-Data-START## Transcript exon combination :: AB059361.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCTGAAGC AGGCAAGAAG ATTTTCATTC AGAAATGTGC GCAGTGCCAC ACAGTGGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001120952.1 |
| CDS | 241..2298 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001127480.1 |
1 | ATGCTGAAGC AGGCAAGAAG ATTTTCATTC AGAAATGTGC GCAGTGCCAC ACAGTGGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity. |
PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system. |
N-Terminal domain of phosphodiesterase-11A4 (PDE11A4) decreases affinity of the catalytic site for substrates and tadalafil, and is involved in oligomerization. |
Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. |
Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): comparison of rat and human PDE11A splicing variants. |
