Bnip3l cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bnip3l
Entrez Gene ID	140923
Full Name	BCL2 interacting protein 3 like
Synonyms	Nix,UV93
General protein information	Preferred Names BCL2 interacting protein 3 like Names BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BCL2/adenovirus E1B 19 kDa-interacting protein 3-like BCL2/adenovirus E1B interacting protein 3-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12
Summary	may be involved in oligodendroglial lineage cell differentiation; may be involved in apoptosis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252091.2	XP_006252153.1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X3
XM_017599570.1	XP_017455059.1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2
XM_017599569.1	XP_017455058.1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1
NM_080888.1	NP_543164.1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Pathways from BioSystems

Homologies

Homo sapiens (human)	BNIP3L	NP_004322.1
Pan troglodytes (chimpanzee)	BNIP3L	XP_001162300.1
Rattus norvegicus (Norway rat)	Bnip3l	NP_543164.1
Gallus gallus (chicken)	BNIP3L	NP_001026056.1
Danio rerio (zebrafish)	bnip3lb	NP_991134.2
	BNIP3L	NP_001032361.1
Bos taurus (cattle)	BNIP3L	NP_001029786.1
Danio rerio (zebrafish)	bnip3la	NP_001012242.1
Mus musculus (house mouse)	Gm10480	XP_006515355.1
Xenopus tropicalis (tropical clawed frog)	bnip3l	NP_001116280.1
Canis lupus familiaris (dog)	BNIP3L	XP_850698.2
Mus musculus (house mouse)	Bnip3l	NP_033891.1

Gene Ontology
Bibliography

Related articles in PubMed

BNIP3L promotes cardiac fibrosis in cardiac fibroblasts through [Ca
Liu W, Wang X, Mei Z, Gong J, Huang L, Gao X, Zhao Y, Ma J, Qian L
Scientific reports7(1)1906(2017 May)

p75 neurotrophin receptor and its novel interaction partner, NIX, are involved in neuronal apoptosis after intracerebral hemorrhage.
Shen J, Chen X, Li H, Wang Y, Huo K, Ke K
Cell and tissue research368(1)13-27(2017 04)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

FGF-2 Transcriptionally Down-Regulates the Expression of BNIP3L via PI3K/Akt/FoxO3a Signaling and Inhibits Necrosis and Mitochondrial Dysfunction Induced by High Concentrations of Hydrogen Peroxide in H9c2 Cells.
Chen Q, Chen X, Han C, Wang Y, Huang T, Du Y, Dong Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology40(6)1678-1691(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

p75(NTR) and NIX may play critical roles in intracerebral hemorrhage-induced neuronal apoptosis in vitro and in vivo.
Title: p75 neurotrophin receptor and its novel interaction partner, NIX, are involved in neuronal apoptosis after intracerebral hemorrhage.

overexpression of BNIP3L in H9C2 cardiomyoblast cells reduced the cardioprotection of FGF-2 in hydrogen peroxide-induced necrosis and mitochondrial dysfunction.
Title: FGF-2 Transcriptionally Down-Regulates the Expression of BNIP3L via PI3K/Akt/FoxO3a Signaling and Inhibits Necrosis and Mitochondrial Dysfunction Induced by High Concentrations of Hydrogen Peroxide in H9c2 Cells.

Up-regulated expression of Bnip3L might be involved in the pathophysiology of intracerebral hemorrhage in rats.
Title: Up-regulated expression of Bnip3L after intracerebral hemorrhage in adult rats.

-stimulated cytoplasmic-nuclear shuttling of the alternately spliced non-mitochondrial Nix isoform and uncover a role for sNix as a modulator of TNFalpha/NFkappaB-stimulated cardiac gene expression
Title: A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor ?B (NF?B)-mediated cardiac transcription.

three members of the BNIP family, BNIP1, BNIP3 and BNIP3L, are expressed in the developing brain with distinct brain region specificity
Title: Differential expression of BNIP family members of BH3-only proteins during the development and after axotomy in the rat.

The following Bnip3l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bnip3l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13171	NM_080888.1 Latest version!	Rattus norvegicus BCL2 interacting protein 3 like (Bnip3l), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa36747	XM_006252091.2 Latest version!	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa58517	XM_017599569.1 Latest version!	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa58518	XM_017599570.1 Latest version!	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bnip3l ( NM_080888.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_543164.1 Rattus norvegicus BCL2 interacting protein 3 like (Bnip3l), mRNA.

Price & Availability↑

CloneID	ORa13171
Clone ID Related Accession (Same CDS sequence)	NM_080888.1
Accession Version	NM_080888.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Rattus norvegicus(Norway rat)
Product	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB077364.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB077364.1, BC098658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906353 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCACT TAGTCGAGCC GCCGCCGCCC CTGCACAACA ACAACAACAA CTGCGAGGAA 
GGGGAGCAGT CCCTGCCGCC GCCCGCTGGC CTCAACAGTT CCTGGGTGGA GCTACCCATG 
AACAGCAGCA ATGGCAACGG TAATGGAAAT GGGAAGAATG GGGGCCTGGA GCACGTTCCT 
TCCTCGTCTT CCATCCACAA TGGAGACATG GAGAAGATCC TTCTGGATGC GCAGCATGAG 
TCGGGACAGA GCAGCTCAAG AGGCAGTTCT CACTGTGACA GCCCTTCACC ACAAGAAGAC 
GGGCAAATAA TGTTTGATGT TGAGATGCAC ACCAGCAGGG ACCACAGCTC TCAGTCAGAA 
GAAGAAGTTG TAGATGGAGA AAAAGAAGTT GAGGCTTTGA AGAAAAGTGC AGACTGGGTA 
TCAGACTGGT CCAGTAGACC CGAAAACATC CCACCCAAAG AGTTCCATTT CAGACACCCT 
AAGCGTGCAG CCTCTCTAAG CATGAGGAAG AGTGGAGCCA TGAAGAAAGG GGGCATTTTC 
TCTGCAGAGT TCCTGAAGGT CTTCATCCCA TCTCTCTTCC TCTCTCACGT GTTGGCTTTG 
GGGCTGGGCA TCTATATCGG AAAACGACTG AGCACACCTT CTGCCAGCAC CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_543164.1
CDS	7..663
Translation	MSHLVEPPPPLHNNNNNCEEGEQSLPPPAGLNSSWVELPMNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY

Target ORF information:

RefSeq Version	NM_080888.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2 interacting protein 3 like (Bnip3l), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080888.1

ORF Insert Sequence:

ATGTCTCACT TAGTCGAGCC GCCGCCGCCC CTGCACAACA ACAACAACAA CTGCGAGGAA 
GGGGAGCAGT CCCTGCCGCC GCCCGCTGGC CTCAACAGTT CCTGGGTGGA GCTACCCATG 
AACAGCAGCA ATGGCAACGG TAATGGAAAT GGGAAGAATG GGGGCCTGGA GCACGTTCCT 
TCCTCGTCTT CCATCCACAA TGGAGACATG GAGAAGATCC TTCTGGATGC GCAGCATGAG 
TCGGGACAGA GCAGCTCAAG AGGCAGTTCT CACTGTGACA GCCCTTCACC ACAAGAAGAC 
GGGCAAATAA TGTTTGATGT TGAGATGCAC ACCAGCAGGG ACCACAGCTC TCAGTCAGAA 
GAAGAAGTTG TAGATGGAGA AAAAGAAGTT GAGGCTTTGA AGAAAAGTGC AGACTGGGTA 
TCAGACTGGT CCAGTAGACC CGAAAACATC CCACCCAAAG AGTTCCATTT CAGACACCCT 
AAGCGTGCAG CCTCTCTAAG CATGAGGAAG AGTGGAGCCA TGAAGAAAGG GGGCATTTTC 
TCTGCAGAGT TCCTGAAGGT CTTCATCCCA TCTCTCTTCC TCTCTCACGT GTTGGCTTTG 
GGGCTGGGCA TCTATATCGG AAAACGACTG AGCACACCTT CTGCCAGCAC CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bnip3l ( XM_006252091.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252153.1 Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa36747
Clone ID Related Accession (Same CDS sequence)	XM_006252091.2
Accession Version	XM_006252091.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006252091.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAGCA GCAATGGCAA CGGTAATGGA AATGGGAAGA ATGGGGGCCT GGAGCACGTT 
CCTTCCTCGT CTTCCATCCA CAATGGAGAC ATGGAGAAGA TCCTTCTGGA TGCGCAGCAT 
GAGTCGGGAC AGAGCAGCTC AAGAGGCAGT TCTCACTGTG ACAGCCCTTC ACCACAAGAA 
GACGGGCAAA TAATGTTTGA TGTTGAGATG CACACCAGCA GGGACCACAG CTCTCAGTCA 
GAAGAAGAAG TTGTAGATGG AGAAAAAGAA GTTGAGGCTT TGAAGAAAAG TGCAGACTGG 
GTATCAGACT GGTCCAGTAG ACCCGAAAAC ATCCCACCCA AAGAGTTCCT TTTCAGACAC 
CCTAAGCGTG CAGCCTCTCT AAGCATGAGG AAGAGTGGAG CCATGAAGAA AGGGGGCATT 
TTCTCTGCAG AGTTCCTGAA GGTCTTCATC CCATCTCTCT TCCTCTCTCA CGTGTTGGCT 
TTGGGGCTGG GCATCTATAT CGGAAAACGA CTGAGCACAC CTTCTGCCAG CACCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252153.1
CDS	1925..2464
Translation	MNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFLFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY

Target ORF information:

RefSeq Version	XM_006252091.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252091.2

ORF Insert Sequence:

ATGAACAGCA GCAATGGCAA CGGTAATGGA AATGGGAAGA ATGGGGGCCT GGAGCACGTT 
CCTTCCTCGT CTTCCATCCA CAATGGAGAC ATGGAGAAGA TCCTTCTGGA TGCGCAGCAT 
GAGTCGGGAC AGAGCAGCTC AAGAGGCAGT TCTCACTGTG ACAGCCCTTC ACCACAAGAA 
GACGGGCAAA TAATGTTTGA TGTTGAGATG CACACCAGCA GGGACCACAG CTCTCAGTCA 
GAAGAAGAAG TTGTAGATGG AGAAAAAGAA GTTGAGGCTT TGAAGAAAAG TGCAGACTGG 
GTATCAGACT GGTCCAGTAG ACCCGAAAAC ATCCCACCCA AAGAGTTCCT TTTCAGACAC 
CCTAAGCGTG CAGCCTCTCT AAGCATGAGG AAGAGTGGAG CCATGAAGAA AGGGGGCATT 
TTCTCTGCAG AGTTCCTGAA GGTCTTCATC CCATCTCTCT TCCTCTCTCA CGTGTTGGCT 
TTGGGGCTGG GCATCTATAT CGGAAAACGA CTGAGCACAC CTTCTGCCAG CACCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bnip3l ( XM_017599569.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455058.1 Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58517
Clone ID Related Accession (Same CDS sequence)	XM_017599569.1
Accession Version	XM_017599569.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCACT TAGTCGAGCC GCCGCCGCCC CTGCACAACA ACAACAACAA CTGCGAGGAA 
GGGGAGCAGT CCCTGCCGCC GCCCGCTGGC CTCAACAGTT CCTGGGTGGA GCTACCCATG 
AACAGCAGCA ATGGCAACGG TAATGGAAAT GGGAAGAATG GGGGCCTGGA GCACGTTCCT 
TCCTCGTCTT CCATCCACAA TGGAGACATG GAGAAGATCC TTCTGGATGC GCAGCATGAG 
TCGGGACAGA GCAGCTCAAG AGGCAGTTCT CACTGTGACA GCCCTTCACC ACAAGAAGAC 
GGGCAAATAA TGTTTGATGT TGAGATGCAC ACCAGCAGGG ACCACAGCTC TCAGTCAGAA 
GAAGAAGTTG TAGATGGAGA AAAAGAAGTT GAGGCTTTGA AGAAAAGTGC AGACTGGGTA 
TCAGACTGGT CCAGTAGACC CGAAAACATC CCACCCAAAG AGTTCCTTTT CAGACACCCT 
AAGCGTGCAG CCTCTCTAAG CATGAGGAAG AGTGGAGCCA TGAAGAAAGG GGGCATTTTC 
TCTGCAGAGT TCCTGAAGGT CTTCATCCCA TCTCTCTTCC TCTCTCACGT GTTGGCTTTG 
GGGCTGGGAT GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455058.1
CDS	101..715
Translation	MSHLVEPPPPLHNNNNNCEEGEQSLPPPAGLNSSWVELPMNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFLFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGW

Target ORF information:

RefSeq Version	XM_017599569.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599569.1

ORF Insert Sequence:

ATGTCTCACT TAGTCGAGCC GCCGCCGCCC CTGCACAACA ACAACAACAA CTGCGAGGAA 
GGGGAGCAGT CCCTGCCGCC GCCCGCTGGC CTCAACAGTT CCTGGGTGGA GCTACCCATG 
AACAGCAGCA ATGGCAACGG TAATGGAAAT GGGAAGAATG GGGGCCTGGA GCACGTTCCT 
TCCTCGTCTT CCATCCACAA TGGAGACATG GAGAAGATCC TTCTGGATGC GCAGCATGAG 
TCGGGACAGA GCAGCTCAAG AGGCAGTTCT CACTGTGACA GCCCTTCACC ACAAGAAGAC 
GGGCAAATAA TGTTTGATGT TGAGATGCAC ACCAGCAGGG ACCACAGCTC TCAGTCAGAA 
GAAGAAGTTG TAGATGGAGA AAAAGAAGTT GAGGCTTTGA AGAAAAGTGC AGACTGGGTA 
TCAGACTGGT CCAGTAGACC CGAAAACATC CCACCCAAAG AGTTCCTTTT CAGACACCCT 
AAGCGTGCAG CCTCTCTAAG CATGAGGAAG AGTGGAGCCA TGAAGAAAGG GGGCATTTTC 
TCTGCAGAGT TCCTGAAGGT CTTCATCCCA TCTCTCTTCC TCTCTCACGT GTTGGCTTTG 
GGGCTGGGAT GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bnip3l ( XM_017599570.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455059.1 Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa58518
Clone ID Related Accession (Same CDS sequence)	XM_017599570.1
Accession Version	XM_017599570.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGACTGG CCGGGCGTGG CGGGTGGACG TGCCGCCCCG CAGGTTCCTG GGTGGAGCTA 
CCCATGAACA GCAGCAATGG CAACGGTAAT GGAAATGGGA AGAATGGGGG CCTGGAGCAC 
GTTCCTTCCT CGTCTTCCAT CCACAATGGA GACATGGAGA AGATCCTTCT GGATGCGCAG 
CATGAGTCGG GACAGAGCAG CTCAAGAGGC AGTTCTCACT GTGACAGCCC TTCACCACAA 
GAAGACGGGC AAATAATGTT TGATGTTGAG ATGCACACCA GCAGGGACCA CAGCTCTCAG 
TCAGAAGAAG AAGTTGTAGA TGGAGAAAAA GAAGTTGAGG CTTTGAAGAA AAGTGCAGAC 
TGGGTATCAG ACTGGTCCAG TAGACCCGAA AACATCCCAC CCAAAGAGTT CCTTTTCAGA 
CACCCTAAGC GTGCAGCCTC TCTAAGCATG AGGAAGAGTG GAGCCATGAA GAAAGGGGGC 
ATTTTCTCTG CAGAGTTCCT GAAGGTCTTC ATCCCATCTC TCTTCCTCTC TCACGTGTTG 
GCTTTGGGGC TGGGCATCTA TATCGGAAAA CGACTGAGCA CACCTTCTGC CAGCACCTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455059.1
CDS	222..824
Translation	MRLAGRGGWTCRPAGSWVELPMNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFLFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY

Target ORF information:

RefSeq Version	XM_017599570.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599570.1

ORF Insert Sequence:

ATGCGACTGG CCGGGCGTGG CGGGTGGACG TGCCGCCCCG CAGGTTCCTG GGTGGAGCTA 
CCCATGAACA GCAGCAATGG CAACGGTAAT GGAAATGGGA AGAATGGGGG CCTGGAGCAC 
GTTCCTTCCT CGTCTTCCAT CCACAATGGA GACATGGAGA AGATCCTTCT GGATGCGCAG 
CATGAGTCGG GACAGAGCAG CTCAAGAGGC AGTTCTCACT GTGACAGCCC TTCACCACAA 
GAAGACGGGC AAATAATGTT TGATGTTGAG ATGCACACCA GCAGGGACCA CAGCTCTCAG 
TCAGAAGAAG AAGTTGTAGA TGGAGAAAAA GAAGTTGAGG CTTTGAAGAA AAGTGCAGAC 
TGGGTATCAG ACTGGTCCAG TAGACCCGAA AACATCCCAC CCAAAGAGTT CCTTTTCAGA 
CACCCTAAGC GTGCAGCCTC TCTAAGCATG AGGAAGAGTG GAGCCATGAA GAAAGGGGGC 
ATTTTCTCTG CAGAGTTCCT GAAGGTCTTC ATCCCATCTC TCTTCCTCTC TCACGTGTTG 
GCTTTGGGGC TGGGCATCTA TATCGGAAAA CGACTGAGCA CACCTTCTGC CAGCACCTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BNIP3L promotes cardiac fibrosis in cardiac fibroblasts through [Ca
Scientific reports7(1)1906(2017 May)
Liu W,Wang X,Mei Z,Gong J,Huang L,Gao X,Zhao Y,Ma J,Qian L

p75 neurotrophin receptor and its novel interaction partner, NIX, are involved in neuronal apoptosis after intracerebral hemorrhage.
Cell and tissue research368(1)13-27(2017 04)
Shen J,Chen X,Li H,Wang Y,Huo K,Ke K

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
Yachie N,Petsalaki E,Mellor JC,Weile J,Jacob Y,Verby M,Ozturk SB,Li S,Cote AG,Mosca R,Knapp JJ,Ko M,Yu A,Gebbia M,Sahni N,Yi S,Tyagi T,Sheykhkarimli D,Roth JF,Wong C,Musa L,Snider J,Liu YC,Yu H,Braun P,Stagljar I,Hao T,Calderwood MA,Pelletier L,Aloy P,Hill DE,Vidal M,Roth FP

FGF-2 Transcriptionally Down-Regulates the Expression of BNIP3L via PI3K/Akt/FoxO3a Signaling and Inhibits Necrosis and Mitochondrial Dysfunction Induced by High Concentrations of Hydrogen Peroxide in H9c2 Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology40(6)1678-1691(2016)
Chen Q,Chen X,Han C,Wang Y,Huang T,Du Y,Dong Z

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Bnip3l cDNA ORF clone, Rattus norvegicus(Norway rat)

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