Olr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension.
Zhang W, Zhu T, Wu W, Ge X, Xiong X, Zhang Z, Hu C
European journal of pharmacology81884-95(2018 Jan)

LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats.
Zhu TT, Zhang WF, Luo P, Qian ZX, Li F, Zhang Z, Hu CP
Life sciences17435-42(2017 Apr)

Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1.
Spaans F, Kao CK, Morton JS, Quon AL, Sawamura T, Tannetta DS, Sargent IL, Davidge ST
PloS one12(7)e0180364(2017)

Negative feedback regulation between let-7g and LOX-1 mediated hypoxia-induced proliferation of in pulmonary artery smooth muscle cells (PASMCs).
Title: Negative feedback regulation between microRNA let-7g and LOX-1 mediated hypoxia-induced PASMCs proliferation.

LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats
Title: LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats.

data support an important role for STBEVs in impairment of vascular function via activation of LOX-1 and reduced nitric oxide mediated vasodilation. Moreover, we postulate that the LOX-1 pathway could be a potential therapeutic target in pathologies associated with vascular dysfunction during pregnancy
Title: Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1.

The in vitro and in vivo models revealed that lipid metabolism disorder and FK506 caused oxidative stress and a fibrogenic response. In addition, decreased levels of LOX1 markedly reduced the levels of TGFb1 in the in vitro model.
Title: Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1.

The inhibition of LOX-1 by RNA interference LOX-1 lentivirus resulted in the loss of PI3K/Akt activation and GATA4 protein expression. GATA4 may play an important role in the LOX-1 and PI3K/Akt regulation of cardiac fibroblast proliferation.
Title: Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces cardiac fibroblast proliferation by suppressing GATA Binding Protein 4.