Fabp5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ?/? (FABP5-PPAR?/?) signaling pathway.
Armstrong EH, Goswami D, Griffin PR, Noy N, Ortlund EA
The Journal of biological chemistry289(21)14941-54(2014 May)

Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress.
Syamsunarno MR, Iso T, Yamaguchi A, Hanaoka H, Putri M, Obokata M, Sunaga H, Koitabashi N, Matsui H, Maeda K, Endo K, Tsushima Y, Yokoyama T, Kurabayashi M
PloS one9(6)e90825(2014)

FABP5 is upregulated in alveolar macrophages during severe inflammation.
Title: Increased expression of epidermal fatty acid-binding protein by alveolar macrophages during acute rejection of rat lungs.

We postulate that a differential regulation of proteasomal function, as demonstrated for TGF-beta 1, can result in an enrichment of proteins, such as EFABP, that mediate physiological functions, such as neurite regeneration.
Title: TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.

A complex interrelationship between glucose and fatty acids in the control of FABP gene expression; FABP3 and 5 may play a role in insulin secretion.
Title: Expression of fatty acid binding proteins 3 and 5 genes in rat pancreatic islets and INS-1E cells: regulation by fatty acids and glucose.

These findings are consistent with the scenario that neurite extension of differentiating PC12 cells, including further stimulation by DHA and EPA, requires sufficient cellular levels of E-FABP.
Title: Expression of E-FABP in PC12 cells increases neurite extension during differentiation: involvement of n-3 and n-6 fatty acids.

C-FABP may play a significant role in regulating adipocyte function in response to changes in nutritional conditions.
Title: Modulation of cutaneous fatty acid-binding protein mRNA expression in rat adipose tissues by hereditary obesity and dietary fats.