Sept2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sept2
Entrez Gene ID	117515
Full Name	septin 2
Synonyms	Nedd5,Vesp11
General protein information	Preferred Names septin 2 Names septin-2 vascular endothelial cell specific protein 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q36
Summary	associates with complex required for neurite outgrowth in neuroendocrine cells and is involved in polarized neurite outgrowth [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006245512.3	XP_006245574.1	septin-2 isoform X1
NM_057148.2	NP_476489.1	septin-2
XM_006245514.1	XP_006245576.1	septin-2 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SEPT2	NP_001039557.1
Mus musculus (house mouse)	Sept2	NP_001153191.1
Drosophila melanogaster (fruit fly)	Sep1	NP_523430.1
Xenopus tropicalis (tropical clawed frog)	sept2	NP_001090723.1
Canis lupus familiaris (dog)	SEPT2	XP_005636032.1
Pan troglodytes (chimpanzee)	SEPT2	XP_003950061.1
	SEPT2	XP_001109436.2
Danio rerio (zebrafish)	sept2	XP_001346020.5
Rattus norvegicus (Norway rat)	Sept2	NP_476489.1
Homo sapiens (human)	SEPT2	NP_001269901.1
Gallus gallus (chicken)	SEPT2	XP_422654.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002645	XP_312282.4

Gene Ontology
Bibliography

Related articles in PubMed

SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins.
Kuo YC, Shen YR, Chen HI, Lin YH, Wang YY, Chen YR, Wang CY, Kuo PL
Journal of cell science128(5)923-34(2015 Mar)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

FHL2-driven molecular network mediated Septin2 knockdown inducing apoptosis in mesangial cell.
Lu Y, Cai G, Cui S, Geng W, Chen D, Wen J, Zhang Y, Zhang F, Xie Y, Fu B, Chen X
Proteomics14(21-22)2485-97(2014 Nov)

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW
PLoS biology11(11)e1001720(2013 Nov)

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length.
Ghossoub R, Hu Q, Failler M, Rouyez MC, Spitzbarth B, Mostowy S, Wolfrum U, Saunier S, Cossart P, Jamesnelson W, Benmerah A
Journal of cell science126(Pt 12)2583-94(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study illustrated the FHL2-driven molecular network controlling SEPT2-mediated apoptosis in mesangial cell and their potential roles in mesangial proliferative nephritis.
Title: FHL2-driven molecular network mediated Septin2 knockdown inducing apoptosis in mesangial cell.

Sept2 regulates growth cone morphology through rearrangement of F-actin and thereby controls neurite outgrowth.
Title: Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells.

Nedd5 may be required for polarized neurite outgrowth, perhaps, by facilitating the exocyst complex function during neuronal differentiation.
Title: The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells.

The following Sept2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sept2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11487	NM_057148.2 Latest version!	Rattus norvegicus septin 2 (Septin2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa11487	XM_006245512.3 Latest version!	Rattus norvegicus septin 2 (Sept2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa11487	XM_006245514.1 Latest version!	Rattus norvegicus septin 2 (Sept2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sept2 ( NM_057148.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_476489.1 Rattus norvegicus septin 2 (Septin2), mRNA.

Price & Availability↑

CloneID	ORa11487
Clone ID Related Accession (Same CDS sequence)	XM_006245512.3 , NM_057148.2 , XM_006245514.1
Accession Version	NM_057148.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	septin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081745.1. On Sep 16, 2004 this sequence version replaced NM_057148.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476489.1
CDS	66..1151
Translation	MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINSRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDTDSSTLGHHV

Target ORF information:

RefSeq Version	NM_057148.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus septin 2 (Septin2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057148.2

ORF Insert Sequence:

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sept2 ( XM_006245512.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245574.1 Rattus norvegicus septin 2 (Sept2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa11487
Clone ID Related Accession (Same CDS sequence)	XM_006245512.3 , NM_057148.2 , XM_006245514.1
Accession Version	XM_006245512.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	septin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245512.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245574.1
CDS	240..1325
Translation	MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINSRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDTDSSTLGHHV

Target ORF information:

RefSeq Version	XM_006245512.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus septin 2 (Sept2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245512.3

ORF Insert Sequence:

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sept2 ( XM_006245514.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245576.1 Rattus norvegicus septin 2 (Sept2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa11487
Clone ID Related Accession (Same CDS sequence)	XM_006245512.3 , NM_057148.2 , XM_006245514.1
Accession Version	XM_006245514.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	septin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245576.1
CDS	124..1209
Translation	MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINSRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDTDSSTLGHHV

Target ORF information:

RefSeq Version	XM_006245514.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus septin 2 (Sept2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245514.1

ORF Insert Sequence:

ATGTCTAAGC AACAACCAAC CCAGTTTATA AATCCAGAAA CTCCTGGCTA TGTTGGATTT 
GCAAATCTCC CCAATCAAGT TCACCGAAAA TCAGTGAAGA AGGGGTTCGA GTTCACTCTG 
ATGGTGGTCG GTGAATCTGG TCTAGGAAAA TCAACTCTCA TAAACAGCTT ATTCTTGACC 
GATCTCTACC CAGAAAGAAT TATTCCTGGA GCTGCAGAAA AAATCGAAAG AACTGTCCAG 
ATAGAGGCTT CGACAGTTGA AATCGAAGAG CGGGGTGTCA AGCTGCGGCT TACAGTAGTG 
GACACGCCTG GCTATGGGGA TGCCATCAAC TCCAGGGATT GTTTCAAGAC AATTATCTCC 
TACATTGATG AGCAGTTTGA ACGCTACCTA CACGATGAGA GTGGACTGAA CAGGCGGCAC 
ATCATTGATA ACAGGGTACA TTGTTGCTTC TACTTCATTT CACCTTTTGG ACATGGACTG 
AAGCCCTTAG ATGTTGCATT TATGAAAGCG ATACACAATA AGGTGAATAT TGTGCCTGTC 
ATTGCGAAAG CTGACACTCT CACTCTGAAG GAGCGGGAGC GGCTAAAGAA AAGGATTTTG 
GATGAAATTG AAGAGCACAG CATTAAAATC TATCATTTAC CTGATGCAGA ATCAGATGAA 
GATGAAGACT TTAAGGAACA GACTAGACTC CTCAAAGCCA GTATCCCATT CTCTGTGGTT 
GGCTCCAACC AGTTGATTGA AGCCAAGGGC AAGAAGGTTA GAGGCCGTCT CTACCCGTGG 
GGCGTTGTCG AGGTGGAGAA CCCAGAACAT AATGACTTTC TGAAGCTGAG AACAATGCTC 
ATCACCCACA TGCAGGACCT ACAGGAAGTG ACCCAAGACC TTCACTATGA AAACTTCCGT 
TCTGAGAGGC TGAAGAGAGG CGGCAGGAAA GTAGAGAATG AGGACATGAA TAAAGACCAG 
ATTTTGCTTG AAAAGGAGGC TGAGCTCCGC CGAATGCAAG AGATGATTGC GAGGATGCAG 
GCGCAGATGC AGATGCAGAT GCAGGGCGGC GACACTGACA GCAGCACTCT TGGGCACCAC 
GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins.
Journal of cell science128(5)923-34(2015 Mar)
Kuo YC,Shen YR,Chen HI,Lin YH,Wang YY,Chen YR,Wang CY,Kuo PL

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

FHL2-driven molecular network mediated Septin2 knockdown inducing apoptosis in mesangial cell.
Proteomics14(21-22)2485-97(2014 Nov)
Lu Y,Cai G,Cui S,Geng W,Chen D,Wen J,Zhang Y,Zhang F,Xie Y,Fu B,Chen X

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
PLoS biology11(11)e1001720(2013 Nov)
Cui C,Chatterjee B,Lozito TP,Zhang Z,Francis RJ,Yagi H,Swanhart LM,Sanker S,Francis D,Yu Q,San Agustin JT,Puligilla C,Chatterjee T,Tansey T,Liu X,Kelley MW,Spiliotis ET,Kwiatkowski AV,Tuan R,Pazour GJ,Hukriede NA,Lo CW

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length.
Journal of cell science126(Pt 12)2583-94(2013 Jun)
Ghossoub R,Hu Q,Failler M,Rouyez MC,Spitzbarth B,Mostowy S,Wolfrum U,Saunier S,Cossart P,Jamesnelson W,Benmerah A

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Sept2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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