Park7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Park7
Entrez Gene ID	117287
Full Name	Parkinsonism associated deglycase
Synonyms	CAP1,DJ-1,Dj1,SP22
General protein information	Preferred Names Parkinsonism associated deglycase Names protein/nucleic acid deglycase DJ-1 Parkinson disease (autosomal recessive, early onset) 7 contraception-associated protein 1 fertility protein SP22 maillard deglycase parkinson disease protein 7 homolog parkinson protein 7 protein DJ-1 protein deglycase DJ-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	displays a specific localization pattern to the anterior-ventral surface of the equatorial segment; may play a role in sperm-egg interactions and fertilization [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001277249.1	NP_001264178.1	protein/nucleic acid deglycase DJ-1 isoform 1
NM_001277251.1	NP_001264180.1	protein/nucleic acid deglycase DJ-1 isoform 2
NM_001277252.1	NP_001264181.1	protein/nucleic acid deglycase DJ-1 isoform 2
NM_057143.2	NP_476484.1	protein/nucleic acid deglycase DJ-1 isoform 2
NM_001277253.1	NP_001264182.1	protein/nucleic acid deglycase DJ-1 isoform 2
NM_001277250.1	NP_001264179.1	protein/nucleic acid deglycase DJ-1 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	PARK7	NP_009193.2
Canis lupus familiaris (dog)	PARK7	XP_859031.1
Mus musculus (house mouse)	Park7	NP_065594.2
Gallus gallus (chicken)	PARK7	NP_989916.1
Danio rerio (zebrafish)	park7	NP_001005938.1
Caenorhabditis elegans (roundworm)	djr-1.2	NP_504132.1
Oryza sativa (rice)	Os06g0531200	NP_001057783.2
Bos taurus (cattle)	PARK7	NP_001015572.1
Drosophila melanogaster (fruit fly)	DJ-1alpha	NP_610916.1
Caenorhabditis elegans (roundworm)	djr-1.1	NP_493696.1
Oryza sativa (rice)	Os01g0217800	NP_001042407.2
Drosophila melanogaster (fruit fly)	dj-1beta	NP_651825.3
Arabidopsis thaliana (thale cress)	AT1G53280	NP_564626.1
Rattus norvegicus (Norway rat)	Park7	NP_001264180.1
Schizosaccharomyces pombe (fission yeast)	SPAC22E12.03c	NP_594829.1
Arabidopsis thaliana (thale cress)	AT3G14990	NP_188117.1
Xenopus tropicalis (tropical clawed frog)	park7	NP_001015851.1

Gene Ontology
Bibliography

Related articles in PubMed

DJ-1 preserving mitochondrial complex I activity plays a critical role in resveratrol-mediated cardioprotection against hypoxia/reoxygenation-induced oxidative stress.
Zhang Y, Li XR, Zhao L, Duan GL, Xiao L, Chen HP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie98545-552(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Low DJ-1 expression is associated with pulmonary arterial hypertension.
Title: Up-regulation of caveolin-1 by DJ-1 attenuates rat pulmonary arterial hypertension by inhibiting TGF?/Smad signaling pathway.

DJ-1 activates autophagy to alleviate cardiac hypertrophy.
Title: DJ-1 activates autophagy in the repression of cardiac hypertrophy.

DJ-1 is necessary for 20C-mediated protection against rotenone-induced oxidative damage, at least in part, by activating PI3K/Akt signaling, and subsequently enhancing the nuclear accumulation of Nrf2.
Title: DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult.

The present study identified DJ-1 as an essential mediator responsible for the beneficial effects of the late phase of ischemic preconditioning in vivo. In addition ischemic preconditioning exerts delayed cardioprotective effects by a hitherto unrecognized underlying mechanism; the attenuation of ischemia/reperfusion -induced oxidative stress via the upregulation of DJ-1.
Title: Involvement of DJ?1 in ischemic preconditioning?induced delayed cardioprotection in vivo.

Data show that high glucose (HG) for 48 h and then exposed to hypoxia for 4 h and reoxygenation for 2 h significantly decreased cell viability in NRK-52E proximal tubular epithelial cells accompanied by a decrease in DJ-1-PARK7 Protein (DJ1) expression.
Title: Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose.

The following Park7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Park7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11473	NM_001277253.1 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11473	NM_001277251.1 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11473	NM_001277250.1 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11473	NM_057143.2 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11473	NM_001277252.1 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11740	NM_001277249.1 Latest version!	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Park7 ( NM_001277251.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001264180.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 3, mRNA.

Price & Availability↑

CloneID	ORa11473
Clone ID Related Accession (Same CDS sequence)	NM_001277251.1 , NM_001277252.1 , NM_057143.2 , NM_001277253.1 , NM_001277250.1
Accession Version	NM_001277251.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and FM055257.1. Transcript Variant: This variant (3) differs in the 5' UTR and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and 3' UTR. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, 4, 5, and 6 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ224480.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01906347, SAMN01906354 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264180.1
CDS	175..744
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD

Target ORF information:

RefSeq Version	NM_001277251.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277251.1

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Park7 ( NM_001277252.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001264181.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 4, mRNA.

Price & Availability↑

CloneID	ORa11473
Clone ID Related Accession (Same CDS sequence)	NM_001277251.1 , NM_001277252.1 , NM_057143.2 , NM_001277253.1 , NM_001277250.1
Accession Version	NM_001277252.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and FM061417.1. Transcript Variant: This variant (4) differs in the 5' UTR and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and 3' UTR. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, 4, 5, and 6 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FM107234.1, FM061417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906354 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264181.1
CDS	56..625
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD

Target ORF information:

RefSeq Version	NM_001277252.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277252.1

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Park7 ( NM_057143.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_476484.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 5, mRNA.

Price & Availability↑

CloneID	ORa11473
Clone ID Related Accession (Same CDS sequence)	NM_001277251.1 , NM_001277252.1 , NM_057143.2 , NM_001277253.1 , NM_001277250.1
Accession Version	NM_057143.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and FM055257.1. On Mar 26, 2013 this sequence version replaced NM_057143.1. Transcript Variant: This variant (5) differs in the 5' UTR and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and 3' UTR. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, 4, 5, and 6 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF157511.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906354 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476484.1
CDS	298..867
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD

Target ORF information:

RefSeq Version	NM_057143.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057143.2

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Park7 ( NM_001277253.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001264182.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 6, mRNA.

Price & Availability↑

CloneID	ORa11473
Clone ID Related Accession (Same CDS sequence)	NM_001277251.1 , NM_001277252.1 , NM_057143.2 , NM_001277253.1 , NM_001277250.1
Accession Version	NM_001277253.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and FM069664.1. Transcript Variant: This variant (6) differs in the 5' UTR and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and 3' UTR. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, 4, 5, and 6 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ220895.1, FQ223564.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906354 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264182.1
CDS	168..737
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD

Target ORF information:

RefSeq Version	NM_001277253.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277253.1

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Park7 ( NM_001277250.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001264179.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 2, mRNA.

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CloneID	ORa11473
Clone ID Related Accession (Same CDS sequence)	NM_001277251.1 , NM_001277252.1 , NM_057143.2 , NM_001277253.1 , NM_001277250.1
Accession Version	NM_001277250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and FM055257.1. Transcript Variant: This variant (2) includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and 3' UTR. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, 4, 5, and 6 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR755577.1, AF157512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906354 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264179.1
CDS	116..685
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSHYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALSGKDMANQVKAPLVLKD

Target ORF information:

RefSeq Version	NM_001277250.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277250.1

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG TCACTACAGC 
TACTCAGAGA GCCGTGTGGA GAAGGACGGC CTCATCCTCA CCAGCCGTGG GCCTGGGACC 
AGCTTCGAGT TTGCGCTGGC CATTGTGGAG GCACTCAGTG GCAAGGACAT GGCTAACCAA 
GTGAAGGCCC CGCTTGTTCT CAAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Park7 ( NM_001277249.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001264178.1 Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 1, mRNA.

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CloneID	ORa11740
Clone ID Related Accession (Same CDS sequence)	NM_001277249.1
Accession Version	NM_001277249.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein/nucleic acid deglycase DJ-1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115172.4 and BC091128.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC091128.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG CTGCTCGCAG 
GACACAGAGA AATCAAGCTG GGCTGACCTG AAAACTTCCT CCTGGTGTCG AGCGTTCGTA 
GCGCAGGCCT CTGGGGGAAG AAAAGTCCTC AAGGATATTA CAGCAAGCCC TCCATGCGAC 
GGTACTGACC TGCCAGTCAA GAGGAGCTGT GAAGGTTACA GGGATAGCCA AACACTGAAG 
GCCCGCTCTG CAGGAGGGGG TTCATGCTTG ACACTGAGAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264178.1
CDS	116..760
Translation	MASKRALVILAKGAEEMETVIPVDIMRRAGIKVTVAGLAGKDPVQCSRDVVICPDTSLEEAKTQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAHEVGFGCKVTSHPLAKDKMMNGSCSQDTEKSSWADLKTSSWCRAFVAQASGGRKVLKDITASPPCDGTDLPVKRSCEGYRDSQTLKARSAGGGSCLTLRA

Target ORF information:

RefSeq Version	NM_001277249.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Parkinsonism associated deglycase (Park7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277249.1

ORF Insert Sequence:

ATGGCATCCA AAAGAGCTCT GGTCATCCTA GCCAAAGGAG CAGAGGAGAT GGAGACAGTG 
ATTCCTGTGG ACATCATGCG GCGAGCTGGG ATTAAAGTCA CCGTTGCAGG CTTGGCTGGG 
AAGGACCCCG TGCAGTGTAG CCGTGATGTA GTGATTTGTC CGGATACCAG TCTGGAAGAA 
GCAAAAACAC AGGGACCATA CGATGTGGTT GTTCTTCCAG GAGGAAATCT GGGTGCACAG 
AACTTATCTG AGTCGGCTTT GGTGAAGGAG ATCCTCAAGG AGCAGGAGAA CAGGAAGGGC 
CTCATAGCTG CCATCTGTGC GGGTCCTACG GCCCTGCTGG CTCACGAAGT AGGCTTTGGA 
TGCAAGGTTA CATCGCACCC ATTGGCTAAG GACAAAATGA TGAACGGCAG CTGCTCGCAG 
GACACAGAGA AATCAAGCTG GGCTGACCTG AAAACTTCCT CCTGGTGTCG AGCGTTCGTA 
GCGCAGGCCT CTGGGGGAAG AAAAGTCCTC AAGGATATTA CAGCAAGCCC TCCATGCGAC 
GGTACTGACC TGCCAGTCAA GAGGAGCTGT GAAGGTTACA GGGATAGCCA AACACTGAAG 
GCCCGCTCTG CAGGAGGGGG TTCATGCTTG ACACTGAGAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DJ-1 preserving mitochondrial complex I activity plays a critical role in resveratrol-mediated cardioprotection against hypoxia/reoxygenation-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie98545-552(2017 Dec)
Zhang Y,Li XR,Zhao L,Duan GL,Xiao L,Chen HP

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Park7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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