Lamc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lamc1
Entrez Gene ID	117036
Full Name	laminin subunit gamma 1
Synonyms	B2e
General protein information	Preferred Names laminin subunit gamma 1 Names laminin subunit gamma-1 laminin, gamma 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q21
Summary	an extracellular matrix protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053966.2	NP_446418.1	laminin subunit gamma-1 precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	lamc1	NP_775384.1
Xenopus tropicalis (tropical clawed frog)	lamc1	NP_001090659.1
Homo sapiens (human)	LAMC1	NP_002284.3
Canis lupus familiaris (dog)	LAMC1	XP_537156.3
Rattus norvegicus (Norway rat)	Lamc1	NP_446418.1
Anopheles gambiae (African malaria mosquito)	LANB2	XP_308240.3
Pan troglodytes (chimpanzee)	LAMC1	XP_001162648.1
Bos taurus (cattle)	LAMC1	NP_001193746.1
Caenorhabditis elegans (roundworm)	lam-2	NP_509204.3
	LOC715265	XP_002808304.1
Mus musculus (house mouse)	Lamc1	NP_034813.2
Gallus gallus (chicken)	LAMC1	XP_001234659.2
Drosophila melanogaster (fruit fly)	LanB2	NP_524006.1

Gene Ontology
Bibliography

Related articles in PubMed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M
Circulation134(11)817-32(2016 Sep)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the Islet-Like Cells: the Role of Extracellular Matrix Proteins.
Pokrywczynska M, Lewandowska MA, Krzyzanowska S, Jundzill A, Rasmus M, Warda K, Gagat M, Deptula A, Helmin-Basa A, Holysz M, Nowacki M, Buchholz L, Bodnar M, Marszalek A, Grzanka A, Jozwicki W, Michalkiewicz J, Drewa T
Archivum immunologiae et therapiae experimentalis63(5)377-84(2015 Oct)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
Soteriou D, Iskender B, Byron A, Humphries JD, Borg-Bartolo S, Haddock MC, Baxter MA, Knight D, Humphries MJ, Kimber SJ
The Journal of biological chemistry288(26)18716-31(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

enhances expression of insulin, and promotes transdifferentiation of bone marrow mesenchymal stem cells into islet-like cells
Title: Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the Islet-Like Cells: the Role of Extracellular Matrix Proteins.

In the hippocampus, thalamus, and piriform cortex both vascular lminin and astrocytic GFAP expression are up regulated following kainic acid injection.
Title: Temporal progression of kainic acid induced changes in vascular laminin expression in rat brain with neuronal and glial correlates.

Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A.
Title: Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A.

Lamc1 transcription can be controlled after transcription initiation.
Title: Transcription of laminin gamma1 chain gene in rat mesangial cells: constitutive and inducible RNA polymerase II recruitment and chromatin states.

Culturing renal mesangial cells with high glucose or glucosamine stimulates laminin gamma1 subunit expression significantly.
Title: Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid.

The following Lamc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lamc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11198	NM_053966.2 Latest version!	Rattus norvegicus laminin subunit gamma 1 (Lamc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lamc1 ( NM_053966.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446418.1 Rattus norvegicus laminin subunit gamma 1 (Lamc1), mRNA.

Price & Availability↑

CloneID	ORa11198
Clone ID Related Accession (Same CDS sequence)	NM_053966.2
Accession Version	NM_053966.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4824bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-07
Organism	Rattus norvegicus(Norway rat)
Product	laminin subunit gamma-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07021411.1 and AABR07021409.1. On Jul 7, 2012 this sequence version replaced NM_053966.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACGGGCG GCAGGCGGGC CGCTCTGGCC CTGCAGCTCC AGCGGCGGCT GTGGCTGCTG 
CTGGCTGTGC TGGCGGCCGT GGCGTGCTGG GTCCGGGCGG CCATGGACGA GTGCGCGGAT 
GAGGGCGGCC GGCCGCAGCG CTGCATGCCG GAGTTTGTTA ATGCCGCCTT CAATGTGACC 
GTGGTGGCTA CCAACACGTG TGGGACTCCA CCCGAGGAGT ACTGCGTGCA GACTGGAGTG 
ACCGGAGTCA CCAAGTCCTG TCACCTGTGC GACGCCGGCC AGCTCCACCT GCAACACGGG 
GCAGCCTTCT TGACCGACTA CAACAACCAG GCCGACACCA CCTGGTGGCA AAGCCAGACT 
ATGCTGGCCG GGGTGCAGTA CCCCAACTCC ATCAACCTCA CGCTGCACCT GGGAAAGGCT 
TTTGACATCA CTTACGTGCG TCTCAAGTTC CACACCAGCC GCCCAGAGAG TTTCGCCATT 
TATAAGCGCA CTCGGGAAGA CGGGCCCTGG ATTCCTTACC AGTACTACAG TGGCTCCTGT 
GAGAACACGT ACTCAAAGGC TAACCGTGGC TTCATCAGGA CGGGAGGAGA TGAGCAGCAG 
GCCTTGTGTA CCGATGAGTT CAGTGACATT TCCCCCCTCA CCGGCGGCAA CGTGGCCTTT 
TCAACTCTGG AAGGAAGGCC GAGTGCCTAC AACTTTGACA ACAGCCCCGT GCTACAGGAA 
TGGGTGACAG CCACTGACAT CAGAGTCACA CTCAATCGCC TGAACACCTT TGGAGATGAA 
GTATTCAATG ACCCCAAAGT CCTCAAGTCT TACTATTATG CAATCTCGGA CTTTGCTGTG 
GGTGGCAGGT GTAAATGTAA TGGACATGCC AGTGAGTGTG TAAAGAACGA GTTTGGGAAG 
CTCGTGTGCA ACTGCAAGCA TAACACATAC GGAGTTGACT GTGAAAAGTG CCTGCCTTTC 
TTCAACGATC GGCCGTGGAG GAGAGCAACT GCCGAGAGTG CCAACCAGTG CCTGCCTTGC 
GACTGCAATG GCCGATCCCA AGAATGCTAC TTTGACCCTG AGCTATACCG TTCCACTGGG 
CACGGTGGCC ACTGTACCAA CTGCCGGGAT AACACAGACG GTGCCAAGTG CGAGAGGTGC 
CGGGAGAACT TCTTCCGCCT GGGGAACACT GAAGCCTGCT CTCCGTGCCA CTGCAGCCCC 
GTTGGTTCTC TCAGCACGCA GTGTGACAGT TACGGCAGGT GCAGCTGTAA GCCCGGAGTG 
ATGGGTGACA AGTGTGACCG TTGCCAGCCT GGGTTCCATT CCCTCACCGA GGCAGGATGC 
AGGCCATGCT CCTGCGACCC TTCTGGCAGC ACCGACGAAT GTAATGTTGA AACAGGAAGA 
TGCGTTTGCA AAGACAACGT CGAAGGCTTC AGCTGTGAGA GATGCAAACC TGGATTTTTT 
AATCTGGAAT CCTCCAATCC TAAGGGTTGC ACACCCTGCT TCTGCTTTGG GCATTCTTCT 
GTGTGCACCA ATGCTGTTGG CTACAGTGTT TATGACATCT CCTCGACCTT TCAGATTGAT 
GAGGACGGGT GGCGTGTGGA GCAGAGAGAT GGCTCGGAGG CGTCTCTTGA GTGGTCCTCA 
GACCGGCAGG ATATTGCTGT GATCTCAGAC ACTTACTTCC CCAGATACTT TGTCGCCCCT 
GCCAAGTTCC TGGGCAACCA GGTCCTGAGT TACGGGCAGA ACCTCTCATT CTCCTTCCGA 
GTGGACAGAC GGGACACTCG CCTCTCCGCA GAGGATCTCG TGCTGGAAGG AGCTGGCTTG 
AGAGTATCCG TGCCCTTGAT CGCTCAGGGC AACTCGTACC CTAGCGAGAC CACTGTGAAG 
TACATCTTCA GACTCCATGA AGCAACAGAT TACCCTTGGA GGCCTGCTCT CTCCCCATTT 
GAATTTCAGA AGCTCCTAAA CAACTTGACC TCTATCAAGA TCCGTGGTAC ATACAGTGAG 
AGGAGCGCTG GATATTTGGA TGATGTCACC TTGCAAAGTG CTCGCCCTGG GCCCGGAGTC 
CCCGCAACGT GGGTGGAGTC CTGCACCTGT CCAGTGGGGT ATGGAGGGCA GTTCTGTGAG 
ACATGCCTCC CAGGCTACAG AAGAGAAACC CCAAGTCTTG GACCTTACAG CCCGTGTGTG 
CTCTGTACCT GTAATGGGCA CAGTGAGACC TGTGACCCCG AGACAGGTGT CTGTGACTGC 
AGAGACAATA CTGCCGGCCC GCACTGTGAG AAATGTAGCG ATGGGTACTA TGGAGACTCA 
ACCCTGGGCA CCTCCTCTGA CTGCCAGCCT TGTCCCTGCC CTGGCGGCTC AAGTTGTGCC 
ATTGTCCCAA AGACAAAGGA AGTGGTGTGC ACACACTGTC CAACTGGCAC TGCCGGCAAG 
AGATGTGAGC TCTGTGATGA CGGCTACTTT GGAGACCCTC TGGGCAGCAA TGGACCCGTG 
AGACTCTGCC GCCCATGTCA GTGCAACGAC AACATAGACC CCAACGCAGT TGGCAACTGC 
AACCGTCTGA CTGGAGAATG CCTGAAGTGC ATCTATAACA CGGCTGGCTT CTACTGCGAC 
CGGTGCAAAG AAGGGTTTTT CGGAAATCCC CTGGCTCCCA ATCCAGCAGA CAAGTGCAAA 
GCCTGCGCCT GCAATCCCTA TGGTACAGTA CAGCAGCAGA GCAGCTGTAA CCCAGTGACC 
GGGCAGTGCC AGTGTCTGCC TCATGTGTCA GGCCGGGACT GTGGCGCTTG TGACCCTGGC 
TTCTACAACC TGCAGAGCGG GCAAGGCTGC GAGAGTTGTG ACTGCCATGC TTTGGGCTCC 
ACCAACGGGC AATGTGACAT CCGCACCGGG CAGTGTGAGT GTCAGCCCGG CATCACCGGT 
CAGCACTGTG AGCGCTGTGA GACCAACCAC TTTGGGTTTG GACCTGAAGG CTGCAAACCT 
TGCGACTGTC ACCACGAAGG ATCCCTTTCG CTCCAATGTA AGGATGACGG CCGTTGTGAA 
TGCAGGGAAG GCTTCGTGGG CAATCGCTGT GACCAGTGTG AAGAGAACTA TTTCTACAAT 
CGGTCTTGGC CTGGCTGCCA AGAGTGTCCG GCTTGTTACC GGCTGGTGAA GGATAAGGTT 
GCTGAGCATC GAGTGAAACT CCAGGAGTTG GAGAGCCTCA TAGCAAACCT CGGGACTGGG 
GATGAGACGG TGACAGATCA AGCCTTTGAG GACAGACTGA AGGAAGCAGA GAGGGAGGTT 
ACAGACCTCC TCCGTGAGGC TCAGGAAGTC AAAGATGTAG ACCAAAATCT GATGGATCGC 
CTTCAGAGAG TAAATAACAG TCTGCACAGC CAAATCAGCC GGCTGCACAA TATCCGGAAC 
ACTATAGAAG AGACGGGGAT CTTGGCTGAG CGAGCGCGGT CCCGAGTGGA GAGCACAGAG 
CAGCTGATTG AGATCGCCTC CAGGGAGCTC GAGAAAGCAA AAATGGCTGC CGCCAATGTG 
TCAATCACTC AGCCAGAGTC TACAGGGGAA CCAAACAACA TGACCCTCTT GGCAGAAGAA 
GCCCGAAGGC TTGCAGAGCG TCATAAACAG GAAGCTGATG ACATTGTACG AGTGGCAAAG 
ACAGCCAACG AGACCTCAGC TGAGGCATAT AATCTGCTTT TGAGGACCCT GGCAGGAGAA 
AATCAAACTG CATTGGAGAT TGAAGAGCTT AACAGGAAGT ATGAACAAGC AAAGAACATC 
TCTCAGGACC TGGAGAAGCA GGCTGCCAGA GTCCATGAGG AAGCCAAGCG AGCAGGTGAC 
AAAGCCGTGG AGATCTATGC CAGTGTGGCC CAGCTGACCC CTGTGGACTC GGAGGCTCTA 
GAGAGTGAAG CAAATAAAAT CAAGAAAGAA GCTGCAGATC TGGACCGTCT GATTGACCAG 
AAGCTAAAAG ATTACGAGGA CCTTAGGGAA GACATGCGAG GAAAGGAACA TGAAGTAAAG 
AACCTTCTAG AGAAGGGGAA AGCCGAACAG CAGACCGCTG ACCAACTCCT AGCTCGAGCC 
GACGCTGCCA AGGCTCTTGC TGAAGAAGCT GCTAAAAAGG GACGCAATAC CTTACAAGAA 
GCTAACGACA TTCTCAACAA CCTGAAAGAT TTTGATAGAC GAGTGAACGA TAACAAGACA 
GCTGCTGAAG AAGCTCTAAG GAGAATTCCC GCCATCAACC GGACCATAGC TGAAGCCAAT 
GAGAAGACAA GGGAGGCACA GCTGGCGCTG GGCAATGCAG CAGCTGACGC CACGGAGGCC 
AAGAACAAAG CCCACGAGGC GGAGAGGATT GCCAGTGGCG TGCAGAAGAA TGCCACCAGT 
ACCAAGGCGG ATGCGGAGAG AACCTTCTCG GAAGTGACAG ACCTGGATAA CGAGGTGAAT 
GGCATGTTGA GGCAGCTAGA GGAAGCGGAG AATGAGCTGA AGAGGAAGCA AGATGATGCC 
GACCAGGACA TGATGATGGC GGGAATGGCT TCACAGGCTG CTCAGGAAGC TGAACTTAAT 
GCCAGAAAAG CCAAAAACTC TGTCAGCAGC CTCCTCAGCC AACTGACCGA CCTCTTGGAG 
CAGCTGGGAC AGCTGGACAC CGTGGACCTG AACAAGCTCA ACGAGATCGA AGGCTCTCTG 
AACAAAGCCA AAGACGAAAT GAAGGTGAGC GACCTGGACA GGAAGGTGTC CAACCTGGAG 
AACGAGGCCC GGAAGCAGGA GGCAGCCATC TTGGACTATG ACCGAGACAT AGCAGAGATC 
ATAAAGGACA TTCACAACCT GGAGGACATC AAGAAGACAC TACCAACAGG CTGCTTTAAC 
ACCCCGTCCA TCGAGAAACC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446418.1
CDS	248..5071
Translation	MTGGRRAALALQLQRRLWLLLAVLAAVACWVRAAMDECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQLHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFGKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESANQCLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSTDECNVETGRCVCKDNVEGFSCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDTYFPRYFVAPAKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLQSARPGPGVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDCGACDPGFYNLQSGQGCESCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAEHRVKLQELESLIANLGTGDETVTDQAFEDRLKEAEREVTDLLREAQEVKDVDQNLMDRLQRVNNSLHSQISRLHNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAKMAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTPVDSEALESEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAERIASGVQKNATSTKADAERTFSEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLTDLLEQLGQLDTVDLNKLNEIEGSLNKAKDEMKVSDLDRKVSNLENEARKQEAAILDYDRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP

Target ORF information:

RefSeq Version	NM_053966.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus laminin subunit gamma 1 (Lamc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053966.2

ORF Insert Sequence:

ATGACGGGCG GCAGGCGGGC CGCTCTGGCC CTGCAGCTCC AGCGGCGGCT GTGGCTGCTG 
CTGGCTGTGC TGGCGGCCGT GGCGTGCTGG GTCCGGGCGG CCATGGACGA GTGCGCGGAT 
GAGGGCGGCC GGCCGCAGCG CTGCATGCCG GAGTTTGTTA ATGCCGCCTT CAATGTGACC 
GTGGTGGCTA CCAACACGTG TGGGACTCCA CCCGAGGAGT ACTGCGTGCA GACTGGAGTG 
ACCGGAGTCA CCAAGTCCTG TCACCTGTGC GACGCCGGCC AGCTCCACCT GCAACACGGG 
GCAGCCTTCT TGACCGACTA CAACAACCAG GCCGACACCA CCTGGTGGCA AAGCCAGACT 
ATGCTGGCCG GGGTGCAGTA CCCCAACTCC ATCAACCTCA CGCTGCACCT GGGAAAGGCT 
TTTGACATCA CTTACGTGCG TCTCAAGTTC CACACCAGCC GCCCAGAGAG TTTCGCCATT 
TATAAGCGCA CTCGGGAAGA CGGGCCCTGG ATTCCTTACC AGTACTACAG TGGCTCCTGT 
GAGAACACGT ACTCAAAGGC TAACCGTGGC TTCATCAGGA CGGGAGGAGA TGAGCAGCAG 
GCCTTGTGTA CCGATGAGTT CAGTGACATT TCCCCCCTCA CCGGCGGCAA CGTGGCCTTT 
TCAACTCTGG AAGGAAGGCC GAGTGCCTAC AACTTTGACA ACAGCCCCGT GCTACAGGAA 
TGGGTGACAG CCACTGACAT CAGAGTCACA CTCAATCGCC TGAACACCTT TGGAGATGAA 
GTATTCAATG ACCCCAAAGT CCTCAAGTCT TACTATTATG CAATCTCGGA CTTTGCTGTG 
GGTGGCAGGT GTAAATGTAA TGGACATGCC AGTGAGTGTG TAAAGAACGA GTTTGGGAAG 
CTCGTGTGCA ACTGCAAGCA TAACACATAC GGAGTTGACT GTGAAAAGTG CCTGCCTTTC 
TTCAACGATC GGCCGTGGAG GAGAGCAACT GCCGAGAGTG CCAACCAGTG CCTGCCTTGC 
GACTGCAATG GCCGATCCCA AGAATGCTAC TTTGACCCTG AGCTATACCG TTCCACTGGG 
CACGGTGGCC ACTGTACCAA CTGCCGGGAT AACACAGACG GTGCCAAGTG CGAGAGGTGC 
CGGGAGAACT TCTTCCGCCT GGGGAACACT GAAGCCTGCT CTCCGTGCCA CTGCAGCCCC 
GTTGGTTCTC TCAGCACGCA GTGTGACAGT TACGGCAGGT GCAGCTGTAA GCCCGGAGTG 
ATGGGTGACA AGTGTGACCG TTGCCAGCCT GGGTTCCATT CCCTCACCGA GGCAGGATGC 
AGGCCATGCT CCTGCGACCC TTCTGGCAGC ACCGACGAAT GTAATGTTGA AACAGGAAGA 
TGCGTTTGCA AAGACAACGT CGAAGGCTTC AGCTGTGAGA GATGCAAACC TGGATTTTTT 
AATCTGGAAT CCTCCAATCC TAAGGGTTGC ACACCCTGCT TCTGCTTTGG GCATTCTTCT 
GTGTGCACCA ATGCTGTTGG CTACAGTGTT TATGACATCT CCTCGACCTT TCAGATTGAT 
GAGGACGGGT GGCGTGTGGA GCAGAGAGAT GGCTCGGAGG CGTCTCTTGA GTGGTCCTCA 
GACCGGCAGG ATATTGCTGT GATCTCAGAC ACTTACTTCC CCAGATACTT TGTCGCCCCT 
GCCAAGTTCC TGGGCAACCA GGTCCTGAGT TACGGGCAGA ACCTCTCATT CTCCTTCCGA 
GTGGACAGAC GGGACACTCG CCTCTCCGCA GAGGATCTCG TGCTGGAAGG AGCTGGCTTG 
AGAGTATCCG TGCCCTTGAT CGCTCAGGGC AACTCGTACC CTAGCGAGAC CACTGTGAAG 
TACATCTTCA GACTCCATGA AGCAACAGAT TACCCTTGGA GGCCTGCTCT CTCCCCATTT 
GAATTTCAGA AGCTCCTAAA CAACTTGACC TCTATCAAGA TCCGTGGTAC ATACAGTGAG 
AGGAGCGCTG GATATTTGGA TGATGTCACC TTGCAAAGTG CTCGCCCTGG GCCCGGAGTC 
CCCGCAACGT GGGTGGAGTC CTGCACCTGT CCAGTGGGGT ATGGAGGGCA GTTCTGTGAG 
ACATGCCTCC CAGGCTACAG AAGAGAAACC CCAAGTCTTG GACCTTACAG CCCGTGTGTG 
CTCTGTACCT GTAATGGGCA CAGTGAGACC TGTGACCCCG AGACAGGTGT CTGTGACTGC 
AGAGACAATA CTGCCGGCCC GCACTGTGAG AAATGTAGCG ATGGGTACTA TGGAGACTCA 
ACCCTGGGCA CCTCCTCTGA CTGCCAGCCT TGTCCCTGCC CTGGCGGCTC AAGTTGTGCC 
ATTGTCCCAA AGACAAAGGA AGTGGTGTGC ACACACTGTC CAACTGGCAC TGCCGGCAAG 
AGATGTGAGC TCTGTGATGA CGGCTACTTT GGAGACCCTC TGGGCAGCAA TGGACCCGTG 
AGACTCTGCC GCCCATGTCA GTGCAACGAC AACATAGACC CCAACGCAGT TGGCAACTGC 
AACCGTCTGA CTGGAGAATG CCTGAAGTGC ATCTATAACA CGGCTGGCTT CTACTGCGAC 
CGGTGCAAAG AAGGGTTTTT CGGAAATCCC CTGGCTCCCA ATCCAGCAGA CAAGTGCAAA 
GCCTGCGCCT GCAATCCCTA TGGTACAGTA CAGCAGCAGA GCAGCTGTAA CCCAGTGACC 
GGGCAGTGCC AGTGTCTGCC TCATGTGTCA GGCCGGGACT GTGGCGCTTG TGACCCTGGC 
TTCTACAACC TGCAGAGCGG GCAAGGCTGC GAGAGTTGTG ACTGCCATGC TTTGGGCTCC 
ACCAACGGGC AATGTGACAT CCGCACCGGG CAGTGTGAGT GTCAGCCCGG CATCACCGGT 
CAGCACTGTG AGCGCTGTGA GACCAACCAC TTTGGGTTTG GACCTGAAGG CTGCAAACCT 
TGCGACTGTC ACCACGAAGG ATCCCTTTCG CTCCAATGTA AGGATGACGG CCGTTGTGAA 
TGCAGGGAAG GCTTCGTGGG CAATCGCTGT GACCAGTGTG AAGAGAACTA TTTCTACAAT 
CGGTCTTGGC CTGGCTGCCA AGAGTGTCCG GCTTGTTACC GGCTGGTGAA GGATAAGGTT 
GCTGAGCATC GAGTGAAACT CCAGGAGTTG GAGAGCCTCA TAGCAAACCT CGGGACTGGG 
GATGAGACGG TGACAGATCA AGCCTTTGAG GACAGACTGA AGGAAGCAGA GAGGGAGGTT 
ACAGACCTCC TCCGTGAGGC TCAGGAAGTC AAAGATGTAG ACCAAAATCT GATGGATCGC 
CTTCAGAGAG TAAATAACAG TCTGCACAGC CAAATCAGCC GGCTGCACAA TATCCGGAAC 
ACTATAGAAG AGACGGGGAT CTTGGCTGAG CGAGCGCGGT CCCGAGTGGA GAGCACAGAG 
CAGCTGATTG AGATCGCCTC CAGGGAGCTC GAGAAAGCAA AAATGGCTGC CGCCAATGTG 
TCAATCACTC AGCCAGAGTC TACAGGGGAA CCAAACAACA TGACCCTCTT GGCAGAAGAA 
GCCCGAAGGC TTGCAGAGCG TCATAAACAG GAAGCTGATG ACATTGTACG AGTGGCAAAG 
ACAGCCAACG AGACCTCAGC TGAGGCATAT AATCTGCTTT TGAGGACCCT GGCAGGAGAA 
AATCAAACTG CATTGGAGAT TGAAGAGCTT AACAGGAAGT ATGAACAAGC AAAGAACATC 
TCTCAGGACC TGGAGAAGCA GGCTGCCAGA GTCCATGAGG AAGCCAAGCG AGCAGGTGAC 
AAAGCCGTGG AGATCTATGC CAGTGTGGCC CAGCTGACCC CTGTGGACTC GGAGGCTCTA 
GAGAGTGAAG CAAATAAAAT CAAGAAAGAA GCTGCAGATC TGGACCGTCT GATTGACCAG 
AAGCTAAAAG ATTACGAGGA CCTTAGGGAA GACATGCGAG GAAAGGAACA TGAAGTAAAG 
AACCTTCTAG AGAAGGGGAA AGCCGAACAG CAGACCGCTG ACCAACTCCT AGCTCGAGCC 
GACGCTGCCA AGGCTCTTGC TGAAGAAGCT GCTAAAAAGG GACGCAATAC CTTACAAGAA 
GCTAACGACA TTCTCAACAA CCTGAAAGAT TTTGATAGAC GAGTGAACGA TAACAAGACA 
GCTGCTGAAG AAGCTCTAAG GAGAATTCCC GCCATCAACC GGACCATAGC TGAAGCCAAT 
GAGAAGACAA GGGAGGCACA GCTGGCGCTG GGCAATGCAG CAGCTGACGC CACGGAGGCC 
AAGAACAAAG CCCACGAGGC GGAGAGGATT GCCAGTGGCG TGCAGAAGAA TGCCACCAGT 
ACCAAGGCGG ATGCGGAGAG AACCTTCTCG GAAGTGACAG ACCTGGATAA CGAGGTGAAT 
GGCATGTTGA GGCAGCTAGA GGAAGCGGAG AATGAGCTGA AGAGGAAGCA AGATGATGCC 
GACCAGGACA TGATGATGGC GGGAATGGCT TCACAGGCTG CTCAGGAAGC TGAACTTAAT 
GCCAGAAAAG CCAAAAACTC TGTCAGCAGC CTCCTCAGCC AACTGACCGA CCTCTTGGAG 
CAGCTGGGAC AGCTGGACAC CGTGGACCTG AACAAGCTCA ACGAGATCGA AGGCTCTCTG 
AACAAAGCCA AAGACGAAAT GAAGGTGAGC GACCTGGACA GGAAGGTGTC CAACCTGGAG 
AACGAGGCCC GGAAGCAGGA GGCAGCCATC TTGGACTATG ACCGAGACAT AGCAGAGATC 
ATAAAGGACA TTCACAACCT GGAGGACATC AAGAAGACAC TACCAACAGG CTGCTTTAAC 
ACCCCGTCCA TCGAGAAACC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Circulation134(11)817-32(2016 Sep)
Barallobre-Barreiro J,Gupta SK,Zoccarato A,Kitazume-Taneike R,Fava M,Yin X,Werner T,Hirt MN,Zampetaki A,Viviano A,Chong M,Bern M,Kourliouros A,Domenech N,Willeit P,Shah AM,Jahangiri M,Schaefer L,Fischer JW,Iozzo RV,Viner R,Thum T,Heineke J,Kichler A,Otsu K,Mayr M

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the Islet-Like Cells: the Role of Extracellular Matrix Proteins.
Archivum immunologiae et therapiae experimentalis63(5)377-84(2015 Oct)
Pokrywczynska M,Lewandowska MA,Krzyzanowska S,Jundzill A,Rasmus M,Warda K,Gagat M,Deptula A,Helmin-Basa A,Holysz M,Nowacki M,Buchholz L,Bodnar M,Marszalek A,Grzanka A,Jozwicki W,Michalkiewicz J,Drewa T

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
The Journal of biological chemistry288(26)18716-31(2013 Jun)
Soteriou D,Iskender B,Byron A,Humphries JD,Borg-Bartolo S,Haddock MC,Baxter MA,Knight D,Humphries MJ,Kimber SJ

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Lamc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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