Lmnb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lmnb1
Entrez Gene ID	116685
Full Name	lamin B1
General protein information	Preferred Names lamin B1 Names lamin-B1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1
Summary	human homolog is a nuclear lamina protein; involved in nuclear stability, chromatin structure and gene expression [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053905.1	NP_446357.1	lamin-B1

Pathways from BioSystems

Homologies

	LMNB1	XP_001097340.1
Rattus norvegicus (Norway rat)	Lmnb1	NP_446357.1
Gallus gallus (chicken)	LMNB1	NP_990617.1
Xenopus tropicalis (tropical clawed frog)	lmnb1	NP_989198.1
Canis lupus familiaris (dog)	LMNB1	XP_531892.3
Mus musculus (house mouse)	Lmnb1	NP_034851.2
Caenorhabditis elegans (roundworm)	lmn-1	NP_492371.1
Homo sapiens (human)	LMNB1	NP_005564.1
Danio rerio (zebrafish)	lmnb1	NP_694504.2
Pan troglodytes (chimpanzee)	LMNB1	XP_001158070.2
Bos taurus (cattle)	LMNB1	NP_001096765.1

Gene Ontology
Bibliography

Related articles in PubMed

Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development.
Karmodiya K, Anamika K, Muley V, Pradhan SJ, Bhide Y, Galande S
Scientific reports46076(2014 Aug)

Expression alterations of genes on both neuronal and glial development in rats after developmental exposure to 6-propyl-2-thiouracil.
Shiraki A, Saito F, Akane H, Takeyoshi M, Imatanaka N, Itahashi M, Yoshida T, Shibutani M
Toxicology letters228(3)225-34(2014 Aug)

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Fouillade C, Baron-Menguy C, Domenga-Denier V, Thibault C, Takamiya K, Huganir R, Joutel A
Arteriosclerosis, thrombosis, and vascular biology33(1)76-86(2013 Jan)

Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice.
De Castro SC, Malhas A, Leung KY, Gustavsson P, Vaux DJ, Copp AJ, Greene ND
PLoS genetics8(11)e1003059(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This differential expression pattern of lamin b1 in retinal neurons suggests that they may be involved in cellular differentiation and expression of cell-specific genes in individual retinal neurons.
Title: Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina.

We now show that epitope masking in the nucleus is often responsible for failure to detect emerin and lamins in human, rat and pig tissues.
Title: The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking.

The following Lmnb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lmnb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11017	NM_053905.1 Latest version!	Rattus norvegicus lamin B1 (Lmnb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lmnb1 ( NM_053905.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446357.1 Rattus norvegicus lamin B1 (Lmnb1), mRNA.

Price & Availability↑

CloneID	ORa11017
Clone ID Related Accession (Same CDS sequence)	NM_053905.1
Accession Version	NM_053905.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	lamin-B1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U72353.1. On or before Jan 12, 2005 this sequence version replaced XM_346512.1, XM_347355.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U72353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGACCG CGACCCCCGT GCAGCAGCGG GCGGGCAGCC GCGCCAGCGC CCCCGCCACG 
CCGTTCAGCC CCACGCGCCT GTCGCGGCTG CAGGAGAAAG AGGAGCTGCG CGAGCTCAAC 
GACCGTCTGG CGGTGTATAT TGACAAGGTG CGCAGCTTGG AGACGGAGAA CAGCGCGCTG 
CAGCTGCAGG TGACCGAGCG CGAGGAGGTG CGCGGCCGCG AGCTCACCGG GCTCAAGGCT 
CTCTACGAGA CCGAGCTGGC CGACGCACGC CGCGCTCTAG ACGACACGGC CCGCGAGCGC 
GCCAAGCTAC AGATCGAGCT GGGCAAGTTC AAGGCCGAGC ACGACCAGCT GCTGCTCAAT 
TATGCTAAGA AGGAGTCTGA TCTCAGTGGA GCCCAGATCA AGCTTCGAGA GTATGAGGCC 
GCGCTAAACT CTAAGGATGC AGCACTGGCT ACTGCCCTTG GGGACAAAAA GAGTTTAGAG 
GGAGACTTGG AGGATCTGAA AGACCAGATT GCCCAGTTGG AAGCATCCCT ATCTGCCGCC 
AAAAAGCAGT TGGCGGATGA GACTTTGCTT AAAGTGGATC TGGAGAACCG TTGTCAGAGC 
CTTACTGAGG ACTTGGAGTT CCGTAAAAAT ATGTATGAAG AGGAGATCAA TGAGACAAGA 
AGGAAGCATG AGACGCGCCT GGTGGAGGTG GACTCCGGGC GTCAGATTGA GTATGAGTAC 
AAGCTGGCTC AAGCCCTGCA CGAGATGAGA GAGCAGCACG ACGCGCAGGT GAGGCTGTAT 
AAGGAAGAGC TGGAGCAGAC CTACCACGCC AAGCTTGAGA ATGCCAGGCT GTCATCAGAG 
ATGAACACTT CCACTGTCAA CAGTGCCAGG GGAGGAATGA TGGAGAGCCG GATGAGGATC 
GAGAGCCTTT CCTCTCAGCT TTCTAACCTG CAGAAAGATT CTAGAGCATG CTTGGAAAGG 
ATTCAAGAAT TGGAGGACAT GCTTGCTAAA GAGAGAGACA ACTCACGCCG CATGCTGTCT 
GACAAAGAGA GAGAGATGGC GGAAATAAGG GACCAGATGC AGCAGCAGCT GAATGATTAC 
GAACAGCTGC TTGACGTGAA GCTGGCCCTG GACATGGAGA TCAGCGCCTA CAGGAAACTC 
TTGGAAGGCG AAGAAGAGCG GTTAAAGCTC TCTCCAAGTC CTTCTTCCCG AGTGACCGTG 
TCCAGAGCCT CGTCCAGCCG CAGTGTGCGC ACCACCAGAG GAAAGCGGAA GAGAGTTGAT 
GTGGAAGAAT CAGAGGCGAG CAGTAGTGTT AGCATTTCCC ACTCTGCTTC AGCCACGGGG 
AATGTGTGCA TTGAAGAGAT AGATGTTGAT GGGAAGTTTA TTCGCTTGAA GAACACTTCT 
GAACAGGATC AACCAATGGG AGGCTGGGAG ATGATCAGAA AAATTGGAGA CACATCAGTC 
AGTTACAAAT ATACCTCAAG ATATGTGCTG AAGGCCGGCC AGACTGTTAC AGTATGGGCT 
GCAAATGCTG GAGTCACAGC CAGTCCTCCA ACTGACCTCA TCTGGAAGAA CCAGAACTCT 
TGGGGCACTG GCGAGGATGT GAAGGTTGTG TTGAAGAATT CTCAGGGAGA GGAGGTTGCT 
CAGAGAAGCA CAGTCTTCAA AACTACCATA CCTGAGGAGG AGGAGGAGGA GGAGGAGGAG 
CCCATCGGAG TGCCCCTGGA GGAGGAACGT TTCCACCAGC AGGGAACCCC AAGAGCATCC 
AATAAAAGCT GTGCCATTAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446357.1
CDS	327..2090
Translation	MATATPVQQRAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLEEERFHQQGTPRASNKSCAIM

Target ORF information:

RefSeq Version	NM_053905.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lamin B1 (Lmnb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053905.1

ORF Insert Sequence:

ATGGCGACCG CGACCCCCGT GCAGCAGCGG GCGGGCAGCC GCGCCAGCGC CCCCGCCACG 
CCGTTCAGCC CCACGCGCCT GTCGCGGCTG CAGGAGAAAG AGGAGCTGCG CGAGCTCAAC 
GACCGTCTGG CGGTGTATAT TGACAAGGTG CGCAGCTTGG AGACGGAGAA CAGCGCGCTG 
CAGCTGCAGG TGACCGAGCG CGAGGAGGTG CGCGGCCGCG AGCTCACCGG GCTCAAGGCT 
CTCTACGAGA CCGAGCTGGC CGACGCACGC CGCGCTCTAG ACGACACGGC CCGCGAGCGC 
GCCAAGCTAC AGATCGAGCT GGGCAAGTTC AAGGCCGAGC ACGACCAGCT GCTGCTCAAT 
TATGCTAAGA AGGAGTCTGA TCTCAGTGGA GCCCAGATCA AGCTTCGAGA GTATGAGGCC 
GCGCTAAACT CTAAGGATGC AGCACTGGCT ACTGCCCTTG GGGACAAAAA GAGTTTAGAG 
GGAGACTTGG AGGATCTGAA AGACCAGATT GCCCAGTTGG AAGCATCCCT ATCTGCCGCC 
AAAAAGCAGT TGGCGGATGA GACTTTGCTT AAAGTGGATC TGGAGAACCG TTGTCAGAGC 
CTTACTGAGG ACTTGGAGTT CCGTAAAAAT ATGTATGAAG AGGAGATCAA TGAGACAAGA 
AGGAAGCATG AGACGCGCCT GGTGGAGGTG GACTCCGGGC GTCAGATTGA GTATGAGTAC 
AAGCTGGCTC AAGCCCTGCA CGAGATGAGA GAGCAGCACG ACGCGCAGGT GAGGCTGTAT 
AAGGAAGAGC TGGAGCAGAC CTACCACGCC AAGCTTGAGA ATGCCAGGCT GTCATCAGAG 
ATGAACACTT CCACTGTCAA CAGTGCCAGG GGAGGAATGA TGGAGAGCCG GATGAGGATC 
GAGAGCCTTT CCTCTCAGCT TTCTAACCTG CAGAAAGATT CTAGAGCATG CTTGGAAAGG 
ATTCAAGAAT TGGAGGACAT GCTTGCTAAA GAGAGAGACA ACTCACGCCG CATGCTGTCT 
GACAAAGAGA GAGAGATGGC GGAAATAAGG GACCAGATGC AGCAGCAGCT GAATGATTAC 
GAACAGCTGC TTGACGTGAA GCTGGCCCTG GACATGGAGA TCAGCGCCTA CAGGAAACTC 
TTGGAAGGCG AAGAAGAGCG GTTAAAGCTC TCTCCAAGTC CTTCTTCCCG AGTGACCGTG 
TCCAGAGCCT CGTCCAGCCG CAGTGTGCGC ACCACCAGAG GAAAGCGGAA GAGAGTTGAT 
GTGGAAGAAT CAGAGGCGAG CAGTAGTGTT AGCATTTCCC ACTCTGCTTC AGCCACGGGG 
AATGTGTGCA TTGAAGAGAT AGATGTTGAT GGGAAGTTTA TTCGCTTGAA GAACACTTCT 
GAACAGGATC AACCAATGGG AGGCTGGGAG ATGATCAGAA AAATTGGAGA CACATCAGTC 
AGTTACAAAT ATACCTCAAG ATATGTGCTG AAGGCCGGCC AGACTGTTAC AGTATGGGCT 
GCAAATGCTG GAGTCACAGC CAGTCCTCCA ACTGACCTCA TCTGGAAGAA CCAGAACTCT 
TGGGGCACTG GCGAGGATGT GAAGGTTGTG TTGAAGAATT CTCAGGGAGA GGAGGTTGCT 
CAGAGAAGCA CAGTCTTCAA AACTACCATA CCTGAGGAGG AGGAGGAGGA GGAGGAGGAG 
CCCATCGGAG TGCCCCTGGA GGAGGAACGT TTCCACCAGC AGGGAACCCC AAGAGCATCC 
AATAAAAGCT GTGCCATTAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development.
Scientific reports46076(2014 Aug)
Karmodiya K,Anamika K,Muley V,Pradhan SJ,Bhide Y,Galande S

Expression alterations of genes on both neuronal and glial development in rats after developmental exposure to 6-propyl-2-thiouracil.
Toxicology letters228(3)225-34(2014 Aug)
Shiraki A,Saito F,Akane H,Takeyoshi M,Imatanaka N,Itahashi M,Yoshida T,Shibutani M

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Arteriosclerosis, thrombosis, and vascular biology33(1)76-86(2013 Jan)
Fouillade C,Baron-Menguy C,Domenga-Denier V,Thibault C,Takamiya K,Huganir R,Joutel A

Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice.
PLoS genetics8(11)e1003059(2012)
De Castro SC,Malhas A,Leung KY,Gustavsson P,Vaux DJ,Copp AJ,Greene ND

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Lmnb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報