Kcnj4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnj4
Entrez Gene ID	116649
Full Name	potassium voltage-gated channel subfamily J member 4
Synonyms	Hirk2
General protein information	Preferred Names potassium voltage-gated channel subfamily J member 4 Names inward rectifier potassium channel 4 BIR11 IRK-3 IRK3 brain inwardly rectifying K(+) channel 2 inward rectifier K(+) channel Kir2.3 potassium channel, inwardly rectifying subfamily J member 4 potassium inwardly-rectifying channel, subfamily J, member 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34
Summary	inwardly-rectifying potassium channel [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594575.1	XP_017450064.1	inward rectifier potassium channel 4 isoform X1
NM_053870.2	NP_446322.2	inward rectifier potassium channel 4
XM_006241963.3	XP_006242025.1	inward rectifier potassium channel 4 isoform X1
XM_006241964.3	XP_006242026.1	inward rectifier potassium channel 4 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KCNJ4	XP_005625941.1
Rattus norvegicus (Norway rat)	Kcnj4	NP_446322.2
Pan troglodytes (chimpanzee)	KCNJ4	XP_525593.2
Gallus gallus (chicken)	KCNJ4	XP_416263.4
Xenopus tropicalis (tropical clawed frog)	kcnj4	XP_002934259.1
Danio rerio (zebrafish)	LOC100331864	XP_002667440.3
Homo sapiens (human)	KCNJ4	NP_004972.1
Mus musculus (house mouse)	Kcnj4	NP_032453.3

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway.
Wang G, Zeng J, Shen CY, Wang ZQ, Chen SD
Biochemical and biophysical research communications374(2)204-9(2008 Sep)

Descending vasa recta endothelia express inward rectifier potassium channels.
Cao C, Lee-Kwon W, Payne K, Edwards A, Pallone TL
American journal of physiology. Renal physiology293(4)F1248-55(2007 Oct)

Differential distribution of individual subunits of strongly inwardly rectifying potassium channels (Kir2 family) in rat brain.
Pr?ss H, Derst C, Lommel R, Veh RW
Brain research. Molecular brain research139(1)63-79(2005 Sep)

A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.
Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA
The Journal of biological chemistry279(18)19051-63(2004 Apr)

Kir2 potassium channels in rat striatum are strategically localized to control basal ganglia function.
Pr?ss H, Wenzel M, Eulitz D, Thomzig A, Karschin A, Veh RW
Brain research. Molecular brain research110(2)203-19(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Down-regulation of the Kir2.3 channel expression contributes to the pathogenesis of temporal lobe epilepsy.
Title: Tenidap, an agonist of the inwardly rectifying K+ channel Kir2.3, delays the onset of cortical epileptiform activity in a model of chronic temporal lobe epilepsy.

Immunohistochemical analysis reveals the expression of Kir2.1, Kir2.2, and Kir2.3/Kcnj4 within spontaneously bursting neurons that regulate the level of pacemaker activity within the developing superficial dorsal horn.
Title: Inward-rectifying potassium (Kir) channels regulate pacemaker activity in spinal nociceptive circuits during early life.

These studies provide an entry point for understanding the novel roles of Kir2.3 in cell models of PD, and they offer clues for the common mechanisms underlying different neurodegenerative conditions.
Title: Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway.

Immunochemical staining verified that both pericytes and endothelial cells of descending vasa recta express K(IR)2.1, K(IR)2.2, and K(IR)2.3 subunits.
Title: Descending vasa recta endothelia express inward rectifier potassium channels.

The following Kcnj4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnj4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa30544	NM_053870.2 Latest version!	Rattus norvegicus potassium inwardly-rectifying channel, subfamily J, member 4 (Kcnj4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa30544	XM_017594575.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa30544	XM_006241964.3 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa30544	XM_006241963.3 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnj4 ( NM_053870.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446322.2 Rattus norvegicus potassium inwardly-rectifying channel, subfamily J, member 4 (Kcnj4), mRNA.

Price & Availability↑

CloneID	ORa30544
Clone ID Related Accession (Same CDS sequence)	XM_017594575.1 , NM_053870.2 , XM_006241963.3 , XM_006241964.3
Accession Version	NM_053870.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2012-04-28
Organism	Rattus norvegicus(Norway rat)
Product	inward rectifier potassium channel 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X87635.1 and AABR03059195.1. On Oct 4, 2005 this sequence version replaced NM_053870.1.

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446322.2
CDS	599..1939
Translation	MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEPSPSGPTAGGPGGNGGGAAPTAAKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEETGIIRMLEFGSHLDLERMQAATLPLDNISYRRESAI

Target ORF information:

RefSeq Version	NM_053870.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium inwardly-rectifying channel, subfamily J, member 4 (Kcnj4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053870.2

ORF Insert Sequence:

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnj4 ( XM_017594575.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450064.1 Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa30544
Clone ID Related Accession (Same CDS sequence)	XM_017594575.1 , NM_053870.2 , XM_006241963.3 , XM_006241964.3
Accession Version	XM_017594575.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inward rectifier potassium channel 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450064.1
CDS	354..1694
Translation	MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEPSPSGPTAGGPGGNGGGAAPTAAKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEETGIIRMLEFGSHLDLERMQAATLPLDNISYRRESAI

Target ORF information:

RefSeq Version	XM_017594575.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594575.1

ORF Insert Sequence:

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnj4 ( XM_006241963.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242025.1 Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30544
Clone ID Related Accession (Same CDS sequence)	XM_017594575.1 , NM_053870.2 , XM_006241963.3 , XM_006241964.3
Accession Version	XM_006241963.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inward rectifier potassium channel 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241963.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242025.1
CDS	130..1470
Translation	MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEPSPSGPTAGGPGGNGGGAAPTAAKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEETGIIRMLEFGSHLDLERMQAATLPLDNISYRRESAI

Target ORF information:

RefSeq Version	XM_006241963.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241963.3

ORF Insert Sequence:

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnj4 ( XM_006241964.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242026.1 Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X3, mRNA.

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CloneID	ORa30544
Clone ID Related Accession (Same CDS sequence)	XM_017594575.1 , NM_053870.2 , XM_006241963.3 , XM_006241964.3
Accession Version	XM_006241964.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inward rectifier potassium channel 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241964.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242026.1
CDS	981..2321
Translation	MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEPSPSGPTAGGPGGNGGGAAPTAAKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEETGIIRMLEFGSHLDLERMQAATLPLDNISYRRESAI

Target ORF information:

RefSeq Version	XM_006241964.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily J member 4 (Kcnj4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241964.3

ORF Insert Sequence:

ATGCACGGAC ACAGCCGCAA CGGGCAGGCC CACGTGCCCA GGCGGAAACG CCGCAACCGC 
TTCGTCAAGA AGAACGGCCA GTGCAACGTG TACTTCGCCA ACCTGAGCAA CAAGTCCCAG 
CGCTACATGG CGGACATCTT CACGACGTGC GTGGACACGC GCTGGCGCTA CATGCTCATG 
ATCTTCTCCG CGGCCTTCCT CGTTTCCTGG CTCTTTTTCG GCCTCCTTTT CTGGTGCATT 
GCCTTTTTCC ACGGTGACCT GGAGCCTAGT CCCTCCGGGC CCACGGCGGG AGGCCCGGGG 
GGCAATGGCG GCGGGGCAGC CCCGACAGCG GCCAAACCGT GTATCATGCA TGTAAACGGC 
TTTTTGGGAG CCTTCCTCTT CTCGGTGGAG ACACAGACGA CCATCGGTTA TGGGTTCCGG 
TGTGTGACAG AGGAGTGCCC GTTGGCGGTC ATCGCAGTGG TTGTCCAGTC CATTGTGGGC 
TGTGTCATCG ACTCCTTCAT GATTGGTACT ATCATGGCCA AGATGGCACG GCCCAAGAAG 
CGGGCGCAGA CCCTGCTGTT CAGCCACCAC GCTGTCATCT CCGTGCGGGA CGGCAAGCTC 
TGCCTGATGT GGCGCGTGGG CAACCTGCGC AAGAGCCACA TCGTGGAGGC CCACGTCCGG 
GCCCAGCTCA TCAAGCCCTA CATGACACAG GAGGGTGAGT ACCTGCCACT GGACCAGCGG 
GACCTCAACG TGGGCTATGA CATTGGCCTG GACCGCATCT TCTTGGTGTC ACCCATCATC 
ATAGTGCATG AGATTGATGA GGACAGTCCA CTCTACGGCA TGGGCAAGGA GGAACTGGAG 
TCGGAGGACT TTGAGATTGT GGTCATCCTG GAGGGCATGG TAGAGGCCAC GGCTATGACC 
ACACAGGCCC GCAGCTCCTA CCTGGCCAGT GAGATCCTGT GGGGCCACCG GTTCGAGCCT 
GTGGTCTTCG AGGAGAAGAG TCACTACAAG GTGGACTACT CACGGTTCCA CAAGACCTAC 
GAGGTGGCTG GCACCCCTTG CTGCTCTGCC CGTGAGCTTC AAGAGAGCAA GATCACGGTG 
CTGCCCGCCC CACCGCCCCC TCCCAGTGCC TTCTGCTATG AGAACGAGTT GGCCCTCATG 
AGCCAGGAGG AAGAAGAAAT GGAAGAGGAG GCTGCTGCCG CAGCAGCCGT GGCTGCCGGC 
CTGGGCCTGG AGGCTGGCTC CAAAGAGGAG ACAGGCATTA TCCGGATGCT TGAGTTTGGC 
AGCCACCTGG ATCTGGAGCG CATGCAAGCC GCTACCCTTC CTCTGGACAA CATTTCTTAC 
CGCAGGGAGT CTGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway.
Biochemical and biophysical research communications374(2)204-9(2008 Sep)
Wang G,Zeng J,Shen CY,Wang ZQ,Chen SD

Descending vasa recta endothelia express inward rectifier potassium channels.
American journal of physiology. Renal physiology293(4)F1248-55(2007 Oct)
Cao C,Lee-Kwon W,Payne K,Edwards A,Pallone TL

Differential distribution of individual subunits of strongly inwardly rectifying potassium channels (Kir2 family) in rat brain.
Brain research. Molecular brain research139(1)63-79(2005 Sep)
Pr?ss H,Derst C,Lommel R,Veh RW

A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.
The Journal of biological chemistry279(18)19051-63(2004 Apr)
Leonoudakis D,Conti LR,Radeke CM,McGuire LM,Vandenberg CA

Kir2 potassium channels in rat striatum are strategically localized to control basal ganglia function.
Brain research. Molecular brain research110(2)203-19(2003 Feb)
Pr?ss H,Wenzel M,Eulitz D,Thomzig A,Karschin A,Veh RW

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Kcnj4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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