Ipo13 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ipo13
Entrez Gene ID	116458
Full Name	importin 13
Synonyms	Imp13,Lgl2
General protein information	Preferred Names importin 13 Names importin-13 late gestation lung 2 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	may be a nuclear import protein involved in import of transcription factors that regulate signal transduction during fetal lung development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017593119.1	XP_017448608.1	importin-13 isoform X1
NM_053778.1	NP_446230.1	importin-13

Pathways from BioSystems

Homologies

	IPO13	XP_002808259.1
Canis lupus familiaris (dog)	IPO13	XP_532612.2
Bos taurus (cattle)	IPO13	NP_001098860.1
Pan troglodytes (chimpanzee)	IPO13	XP_524696.4
Mus musculus (house mouse)	Ipo13	NP_666264.1
Danio rerio (zebrafish)	ipo13	XP_002665826.2
Xenopus tropicalis (tropical clawed frog)	ipo13	XP_002931629.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009571	XP_318583.4
Drosophila melanogaster (fruit fly)	cdm	NP_650682.1
Homo sapiens (human)	IPO13	NP_055467.3
Rattus norvegicus (Norway rat)	Ipo13	NP_446230.1
Gallus gallus (chicken)	IPO13	NP_001006537.1

Gene Ontology
Bibliography

Related articles in PubMed

The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems.
Kanno Y, Miyazaki Y, Inouye Y
Biochimica et biophysica acta1803(8)968-74(2010 Aug)

Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.
Tao T, Lan J, Lukacs GL, Hach? RJ, Kaplan F
American journal of respiratory cell and molecular biology35(6)668-80(2006 Dec)

Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13.
Kahle J, Baake M, Doenecke D, Albig W
Molecular and cellular biology25(13)5339-54(2005 Jul)

A novel karyopherin-beta homolog is developmentally and hormonally regulated in fetal lung.
Zhang C, Sweezey NB, Gagnon S, Muskat B, Koehler D, Post M, Kaplan F
American journal of respiratory cell and molecular biology22(4)451-9(2000 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that nuclear import of CAR is regulated by importin/Ran-GTP systems.
Title: The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems.

Findings support a role for IPO13 in promoting nuclear occupancy of glucocorticoid receptor in a way that strongly potentiates the antiinflammatory effects of glucocorticoids.
Title: Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.

The following Ipo13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ipo13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10622	NM_053778.1 Latest version!	Rattus norvegicus importin 13 (Ipo13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa61089	XM_017593119.1 Latest version!	Rattus norvegicus importin 13 (Ipo13), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ipo13 ( NM_053778.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446230.1 Rattus norvegicus importin 13 (Ipo13), mRNA.

Price & Availability↑

CloneID	ORa10622
Clone ID Related Accession (Same CDS sequence)	NM_053778.1
Accession Version	NM_053778.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	importin-13
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF110195.1. ##Evidence-Data-START## Transcript exon combination :: AF110195.1, BC100658.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCGGC GGGAGGAGCA GCTGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTACGACCC CAATATTGAG 
AACAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCTCCACA GGCCTGGCAT 
TTCAGCTGGC AGCTACTACA GCCAGACAAG GTGCCTGAGA TCCAGTACTT TGGGGCCAGT 
GCCCTGCACA TCAAGATCTC TCGCTATTGG AGTGACATCC CCACCGACCA GTATGAAAGC 
CTAAAGGCGC ACTCTTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA AATTGTGCTG 
ACTCGGCTAT GTGTGGCGCT GGCCTCACTG GCTCTCAGTA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT CCGGCTCTTC CAAGCTGAGG ACTCTCCGGT GGATAGCCAG 
GGCCGTTGTC TGGCCCTGCT AGAGTTGCTG ACGGTACTGC CTGAGGAGTT TCAGACCAGT 
CGCTTGCCCC AGTACCGCAA AGGTCTGGTA CGGGCCAGCC TGGCGGTGGA GTGTGGGGCT 
GTCTTCCCAT TGCTGGAGCA ATTGCTACAA CAGCCCAGCT CTCCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGCTTCTC CAGCTGGGTG CAGCTGGAAG TGCCCCTGCA GGACTGTGAG 
GCGCTCATTC AGGCCGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTTGA CAGCAGCGTG 
GAGGCCATTG TCAATGCTAT CTCCCAGCCA GATGCCCAAA GGTATGTGAA CACACTCCTG 
AAACTCATTC CGTTGGTGCT GGGACTGCAG GAGCAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGCCGC ATTGCTGTGG CCCTGGGCGA GAACCACTCT 
CGGGCCTTGC TAGATCAAGT AGAACACTGG CAAAGCTTCC TGGCACTTGT CAACATGATC 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTCACT 
CTCACCTTCT GGTACACACT GCAGGATGAC ATTCTGTCCT TTGAGGCAGA GAAGCAGGCT 
GTGTACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGACGTGCT TCTGCACAAG 
GCCCAGTTCC CCTCTGATGA GGAATATGGA TTCTGGTCCT CAGATGAAAA GGAGCAGTTC 
CGAATCTACA GGGTGGACAT TTCAGACACA CTCATGTATG TGTATGAGAT GCTGGGGGCT 
GAGCTGCTTA GCAACCTCTA TGACAAACTG GGCCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA AGCCCTGCTC TATGGCTTCC AGTCCATTGC AGAGACCATC 
GATGTCAACT ACTCTGATGT GGTACCCGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA TACCGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CTGTCATGAT CAACAGCGTT CTGCCCCTTG TGCTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCATC AGTGTCGACC CTCAAAAAGA TCTGCCGAGA GTGCAAGTAT 
GAACTGCCGC CCTATGCTGC CAACATTGTA GCTGTCTCCC AGGATGTGCT GATGAAGCAG 
ATCCACAAGA CTAGCCAGTG CATGTGGCTG ATGCAGGCAC TGGGCTTCCT GCTGTCAGCC 
CTGCAGGTAG AGGAGAACCT GAAGAACCTG CACTCACTCA TCTCTACCTA CATCCAACAG 
CTGGAGAAGC TGGCAGAAGA GATACCTAAA CCCTCCAACA AGCTGGCCAT TGTACACATC 
TTGGGGCTTC TTTCCAACCT CTTTACCACA CTGGACGTCA GTCATCATGA AGATGATCAC 
GAAGGCCCTG AGCTCCGAAA GCTGCCAGTG CCACAGGGAC CCAACCCGGT GGTGGTCGTG 
CTGCAGCAGG TCTTCCAGCT CATCCAGAAG GTGCTGAGCA AGTGGCTGAG TGATGCCCAG 
GTGGTCGAGG CGGTGTGTGC CATCTTTGAG AAGTCTGTTA AGACACTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT CTGTGAGATG CTGGGTCGGA TGTACAGCAC CGTTCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGTTG GTCCACATCT TTGCCCACGA GCCTGCCCAC 
TTTCCCCCAA TAGAGGCCCT CTTCCTGCTG GTGACCTCCG TCACACTCTC TCTCTTCCAA 
CAAGGGCCCA GGGACCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
TTGAAGCGGA AGCCAGATTT GTTCCAGTGT GAGCGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACTGAGC TGCTGCCTCG ATGTGGGGAA ATAGAATCTG TGGGGAAAGT GGTACAGGAA 
GATGGCCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATCG GGGGCCAGGC CTCCCGTAGC 
CTCATGGACT GTTTTGCTGA CATCCTGTTC GCCCTGAACA AACACTGCTT CAGCCTCCTA 
AGCATGTGGA TCAAGGAGGC TCTACAGCCA CCTGGCTTTC CATCTGCCCG TCTCAGCCCT 
GAGCAGAAGG ACACCTTCAG CCAGCAGATA CTTCGTGAGC GAGTGAACAA GAGACGGGTG 
AAGGAGATGG TGAAGGAATT TACACTGCTG TGCCGGGGGC TACATGGCAC AGACTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446230.1
CDS	605..3496
Translation	MERREEQLGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAHSFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDSQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRASLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYELPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEENLKNLHSLISTYIQQLEKLAEEIPKPSNKLAIVHILGLLSNLFTTLDVSHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLSDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTVPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLSLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFQCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEIESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY

Target ORF information:

RefSeq Version	NM_053778.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus importin 13 (Ipo13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053778.1

ORF Insert Sequence:

ATGGAGCGGC GGGAGGAGCA GCTGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTACGACCC CAATATTGAG 
AACAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCTCCACA GGCCTGGCAT 
TTCAGCTGGC AGCTACTACA GCCAGACAAG GTGCCTGAGA TCCAGTACTT TGGGGCCAGT 
GCCCTGCACA TCAAGATCTC TCGCTATTGG AGTGACATCC CCACCGACCA GTATGAAAGC 
CTAAAGGCGC ACTCTTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA AATTGTGCTG 
ACTCGGCTAT GTGTGGCGCT GGCCTCACTG GCTCTCAGTA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT CCGGCTCTTC CAAGCTGAGG ACTCTCCGGT GGATAGCCAG 
GGCCGTTGTC TGGCCCTGCT AGAGTTGCTG ACGGTACTGC CTGAGGAGTT TCAGACCAGT 
CGCTTGCCCC AGTACCGCAA AGGTCTGGTA CGGGCCAGCC TGGCGGTGGA GTGTGGGGCT 
GTCTTCCCAT TGCTGGAGCA ATTGCTACAA CAGCCCAGCT CTCCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGCTTCTC CAGCTGGGTG CAGCTGGAAG TGCCCCTGCA GGACTGTGAG 
GCGCTCATTC AGGCCGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTTGA CAGCAGCGTG 
GAGGCCATTG TCAATGCTAT CTCCCAGCCA GATGCCCAAA GGTATGTGAA CACACTCCTG 
AAACTCATTC CGTTGGTGCT GGGACTGCAG GAGCAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGCCGC ATTGCTGTGG CCCTGGGCGA GAACCACTCT 
CGGGCCTTGC TAGATCAAGT AGAACACTGG CAAAGCTTCC TGGCACTTGT CAACATGATC 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTCACT 
CTCACCTTCT GGTACACACT GCAGGATGAC ATTCTGTCCT TTGAGGCAGA GAAGCAGGCT 
GTGTACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGACGTGCT TCTGCACAAG 
GCCCAGTTCC CCTCTGATGA GGAATATGGA TTCTGGTCCT CAGATGAAAA GGAGCAGTTC 
CGAATCTACA GGGTGGACAT TTCAGACACA CTCATGTATG TGTATGAGAT GCTGGGGGCT 
GAGCTGCTTA GCAACCTCTA TGACAAACTG GGCCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA AGCCCTGCTC TATGGCTTCC AGTCCATTGC AGAGACCATC 
GATGTCAACT ACTCTGATGT GGTACCCGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA TACCGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CTGTCATGAT CAACAGCGTT CTGCCCCTTG TGCTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCATC AGTGTCGACC CTCAAAAAGA TCTGCCGAGA GTGCAAGTAT 
GAACTGCCGC CCTATGCTGC CAACATTGTA GCTGTCTCCC AGGATGTGCT GATGAAGCAG 
ATCCACAAGA CTAGCCAGTG CATGTGGCTG ATGCAGGCAC TGGGCTTCCT GCTGTCAGCC 
CTGCAGGTAG AGGAGAACCT GAAGAACCTG CACTCACTCA TCTCTACCTA CATCCAACAG 
CTGGAGAAGC TGGCAGAAGA GATACCTAAA CCCTCCAACA AGCTGGCCAT TGTACACATC 
TTGGGGCTTC TTTCCAACCT CTTTACCACA CTGGACGTCA GTCATCATGA AGATGATCAC 
GAAGGCCCTG AGCTCCGAAA GCTGCCAGTG CCACAGGGAC CCAACCCGGT GGTGGTCGTG 
CTGCAGCAGG TCTTCCAGCT CATCCAGAAG GTGCTGAGCA AGTGGCTGAG TGATGCCCAG 
GTGGTCGAGG CGGTGTGTGC CATCTTTGAG AAGTCTGTTA AGACACTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT CTGTGAGATG CTGGGTCGGA TGTACAGCAC CGTTCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGTTG GTCCACATCT TTGCCCACGA GCCTGCCCAC 
TTTCCCCCAA TAGAGGCCCT CTTCCTGCTG GTGACCTCCG TCACACTCTC TCTCTTCCAA 
CAAGGGCCCA GGGACCATCC TGATATTGTT GATTCATTTA TGCAACTCCT GGCACAGGCT 
TTGAAGCGGA AGCCAGATTT GTTCCAGTGT GAGCGATTGG ATGTCAAAGC TGTGTTCCAG 
TGTGCTGTGC TGGCCCTCAA GTTCCCTGAG GCACCTACTG TCAAGGCCTC CTGTGGCTTC 
TTTACTGAGC TGCTGCCTCG ATGTGGGGAA ATAGAATCTG TGGGGAAAGT GGTACAGGAA 
GATGGCCGTA TGCTGCTCAT AGCAGTGCTG GAGGCCATCG GGGGCCAGGC CTCCCGTAGC 
CTCATGGACT GTTTTGCTGA CATCCTGTTC GCCCTGAACA AACACTGCTT CAGCCTCCTA 
AGCATGTGGA TCAAGGAGGC TCTACAGCCA CCTGGCTTTC CATCTGCCCG TCTCAGCCCT 
GAGCAGAAGG ACACCTTCAG CCAGCAGATA CTTCGTGAGC GAGTGAACAA GAGACGGGTG 
AAGGAGATGG TGAAGGAATT TACACTGCTG TGCCGGGGGC TACATGGCAC AGACTACACA 
GCTGACTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ipo13 ( XM_017593119.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448608.1 Rattus norvegicus importin 13 (Ipo13), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61089
Clone ID Related Accession (Same CDS sequence)	XM_017593119.1
Accession Version	XM_017593119.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2379bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	importin-13 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGC GGGAGGAGCA GCTGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTACGACCC CAATATTGAG 
AACAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCTCCACA GGCCTGGCAT 
TTCAGCTGGC AGCTACTACA GCCAGACAAG GTGCCTGAGA TCCAGTACTT TGGGGCCAGT 
GCCCTGCACA TCAAGATCTC TCGCTATTGG AGTGACATCC CCACCGACCA GTATGAAAGC 
CTAAAGGCGC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA AATTGTGCTG 
ACTCGGCTAT GTGTGGCGCT GGCCTCACTG GCTCTCAGTA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT CCGGCTCTTC CAAGCTGAGG ACTCTCCGGT GGATAGCCAG 
GGCCGTTGTC TGGCCCTGCT AGAGTTGCTG ACGGTACTGC CTGAGGAGTT TCAGACCAGT 
CGCTTGCCCC AGTACCGCAA AGGTCTGGTA CGGGCCAGCC TGGCGGTGGA GTGTGGGGCT 
GTCTTCCCAT TGCTGGAGCA ATTGCTACAA CAGCCCAGCT CTCCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGCTTCTC CAGCTGGGTG CAGCTGGAAG TGCCCCTGCA GGACTGTGAG 
GCGCTCATTC AGGCCGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTTGA CAGCAGCGTG 
GAGGCCATTG TCAATGCTAT CTCCCAGCCA GATGCCCAAA GGTATGTGAA CACACTCCTG 
AAACTCATTC CGTTGGTGCT GGGACTGCAG GAGCAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGCCGC ATTGCTGTGG CCCTGGGCGA GAACCACTCT 
CGGGCCTTGC TAGATCAAGT AGAACACTGG CAGAGCTTCC TGGCACTTGT CAACATGATC 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTCACT 
CTCACCTTCT GGTACACACT GCAGGATGAC ATTCTGTCCT TTGAGGCAGA GAAGCAGGCT 
GTGTACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGACGTGCT TCTGCACAAG 
GCCCAGTTCC CCTCTGATGA GGAATATGGA TTCTGGTCCT CAGATGAAAA GGAGCAGTTC 
CGAATCTACA GGGTGGACAT TTCAGACACA CTCATGTATG TGTATGAGAT GCTGGGGGCT 
GAGCTGCTTA GCAACCTCTA TGACAAACTG GGCCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA AGCCCTGCTC TATGGCTTCC AGTCCATTGC AGAGACCATC 
GATGTCAACT ACTCTGATGT GGTACCCGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA TACCGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CTGTCATGAT CAACAGCGTT CTGCCCCTTG TGCTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCATC AGTGTCGACC CTCAAAAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCGC CCTATGCTGC CAACATTGTA GCTGTCTCCC AGGATGTGCT GATGAAGCAG 
ATCCACAAGA CTAGCCAGTG CATGTGGCTG ATGCAGGCAC TGGGCTTCCT GCTGTCAGCC 
CTGCAGGTAG AGGAGATCCT GAAGAACCTG CACTCACTCA TCTCTCCCTA CATCCAACAG 
CTGGAGAAGC TGGCAGAAGA GATACCTAAT CCCTCCAACA AGCTGGCCAT TGTCCACATC 
TTGGGGCTTC TTTCCAACCT CTTTACCACA CTGGACGTCA GTCATCATGA AGATGATCAC 
GAAGGCCCTG AGCTCCGAAA GCTGCCAGTG CCACAGGGAC CCAACCCGGT GGTGGTCGTG 
CTGCAGCAGG TCTTCCAGCT CATCCAGAAG GTGCTGAGCA AGTGGCTGAG TGATGCCCAG 
GTGGTCGAGG CGGTGTGTGC CATCTTTGAG AAGTCTGTTA AGACACTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT CTGTGAGATG CTGGGTCGGA TGTACAGCAC CGTTCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGTTG GTCCACATCT TTGCCCACGA GCCTGCCCAC 
TTTCCCCCAA TAGAGGCCCT CTTCCTGCTG GTGACCTCCG TCACACTCTC TCTCTTCCAA 
CAAGGCTTTG AAGCGGAAGC CAGATTTGTT CCAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448608.1
CDS	820..3198
Translation	MERREEQLGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDSQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRASLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDVSHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLSDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTVPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLSLFQQGFEAEARFVPV

Target ORF information:

RefSeq Version	XM_017593119.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus importin 13 (Ipo13), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593119.1

ORF Insert Sequence:

ATGGAGCGGC GGGAGGAGCA GCTGGGGGCT GCAGGGGCTG GAGCAGCACC AGCCTTGGAC 
TTCACTGTGG AGAACGTGGA GAAGGCGCTG CACCAGCTCT ACTACGACCC CAATATTGAG 
AACAAGAACC TGGCTCAGAA GTGGCTGATG CAGGCCCAGG TCTCTCCACA GGCCTGGCAT 
TTCAGCTGGC AGCTACTACA GCCAGACAAG GTGCCTGAGA TCCAGTACTT TGGGGCCAGT 
GCCCTGCACA TCAAGATCTC TCGCTATTGG AGTGACATCC CCACCGACCA GTATGAAAGC 
CTAAAGGCGC AGCTCTTCAC CCAGATCACC CGCTTTGCCA GTGGCTCCAA AATTGTGCTG 
ACTCGGCTAT GTGTGGCGCT GGCCTCACTG GCTCTCAGTA TGATGCCTGA CGCTTGGCCA 
TGTGCTGTGG CAGATATGGT CCGGCTCTTC CAAGCTGAGG ACTCTCCGGT GGATAGCCAG 
GGCCGTTGTC TGGCCCTGCT AGAGTTGCTG ACGGTACTGC CTGAGGAGTT TCAGACCAGT 
CGCTTGCCCC AGTACCGCAA AGGTCTGGTA CGGGCCAGCC TGGCGGTGGA GTGTGGGGCT 
GTCTTCCCAT TGCTGGAGCA ATTGCTACAA CAGCCCAGCT CTCCCAGCTG TGTGCGTCAG 
AAGGTGCTCA AGTGCTTCTC CAGCTGGGTG CAGCTGGAAG TGCCCCTGCA GGACTGTGAG 
GCGCTCATTC AGGCCGCCTT TGCTGCTCTG CAGGACTCGG AGCTCTTTGA CAGCAGCGTG 
GAGGCCATTG TCAATGCTAT CTCCCAGCCA GATGCCCAAA GGTATGTGAA CACACTCCTG 
AAACTCATTC CGTTGGTGCT GGGACTGCAG GAGCAACTGC GGCAGGCAGT GCAGAATGGG 
GACATGGAGA CCTCCCATGG CATCTGCCGC ATTGCTGTGG CCCTGGGCGA GAACCACTCT 
CGGGCCTTGC TAGATCAAGT AGAACACTGG CAGAGCTTCC TGGCACTTGT CAACATGATC 
ATGTTCTGCA CAGGCATCCC TGGCCACTAT CCTGTCAATG AGACCACCAG CTCCCTCACT 
CTCACCTTCT GGTACACACT GCAGGATGAC ATTCTGTCCT TTGAGGCAGA GAAGCAGGCT 
GTGTACCAGC AGGTGTACCG GCCAGTCTAC TTCCAGCTGG TGGACGTGCT TCTGCACAAG 
GCCCAGTTCC CCTCTGATGA GGAATATGGA TTCTGGTCCT CAGATGAAAA GGAGCAGTTC 
CGAATCTACA GGGTGGACAT TTCAGACACA CTCATGTATG TGTATGAGAT GCTGGGGGCT 
GAGCTGCTTA GCAACCTCTA TGACAAACTG GGCCGTTTGC TCACCAGCTC AGAGGAGCCC 
TACTCCTGGC AGCACACAGA AGCCCTGCTC TATGGCTTCC AGTCCATTGC AGAGACCATC 
GATGTCAACT ACTCTGATGT GGTACCCGGG CTCATTGGCC TCATCCCACG GATCAGCATC 
AGCAACGTGC AGCTGGCAGA TACCGTCATG TTCACCATTG GAGCTCTGTC TGAATGGCTG 
GCTGACCACC CTGTCATGAT CAACAGCGTT CTGCCCCTTG TGCTGCATGC CCTAGGCAAT 
CCTGAGCTGT CTGTCTCATC AGTGTCGACC CTCAAAAAGA TCTGCCGAGA GTGCAAGTAT 
GACCTGCCGC CCTATGCTGC CAACATTGTA GCTGTCTCCC AGGATGTGCT GATGAAGCAG 
ATCCACAAGA CTAGCCAGTG CATGTGGCTG ATGCAGGCAC TGGGCTTCCT GCTGTCAGCC 
CTGCAGGTAG AGGAGATCCT GAAGAACCTG CACTCACTCA TCTCTCCCTA CATCCAACAG 
CTGGAGAAGC TGGCAGAAGA GATACCTAAT CCCTCCAACA AGCTGGCCAT TGTCCACATC 
TTGGGGCTTC TTTCCAACCT CTTTACCACA CTGGACGTCA GTCATCATGA AGATGATCAC 
GAAGGCCCTG AGCTCCGAAA GCTGCCAGTG CCACAGGGAC CCAACCCGGT GGTGGTCGTG 
CTGCAGCAGG TCTTCCAGCT CATCCAGAAG GTGCTGAGCA AGTGGCTGAG TGATGCCCAG 
GTGGTCGAGG CGGTGTGTGC CATCTTTGAG AAGTCTGTTA AGACACTGCT GGATGACTTT 
GCCCCCATGG TGCCACAGCT CTGTGAGATG CTGGGTCGGA TGTACAGCAC CGTTCCCCAG 
GCCTCTGCTC TTGACCTCAC TCGACAGTTG GTCCACATCT TTGCCCACGA GCCTGCCCAC 
TTTCCCCCAA TAGAGGCCCT CTTCCTGCTG GTGACCTCCG TCACACTCTC TCTCTTCCAA 
CAAGGCTTTG AAGCGGAAGC CAGATTTGTT CCAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems.
Biochimica et biophysica acta1803(8)968-74(2010 Aug)
Kanno Y,Miyazaki Y,Inouye Y

Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.
American journal of respiratory cell and molecular biology35(6)668-80(2006 Dec)
Tao T,Lan J,Lukacs GL,Hach? RJ,Kaplan F

Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13.
Molecular and cellular biology25(13)5339-54(2005 Jul)
Kahle J,Baake M,Doenecke D,Albig W

A novel karyopherin-beta homolog is developmentally and hormonally regulated in fetal lung.
American journal of respiratory cell and molecular biology22(4)451-9(2000 Apr)
Zhang C,Sweezey NB,Gagnon S,Muskat B,Koehler D,Post M,Kaplan F

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Ipo13 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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