Wnt7a cDNA ORF clone, Rattus norvegicus(Norway rat)

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.
Voloshanenko O, Gmach P, Winter J, Kranz D, Boutros M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4832-4844(2017 Nov)

Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1.
Ciani L, Marzo A, Boyle K, Stamatakou E, Lopes DM, Anane D, McLeod F, Rosso SB, Gibb A, Salinas PC
Nature communications68302(2015 Sep)

Supplementation of ketoacids contributes to the up-regulation of the Wnt7a/Akt/p70S6K pathway and the down-regulation of apoptotic and ubiquitin-proteasome systems in the muscle of 5/6 nephrectomised rats.
Wang DT, Lu L, Shi Y, Geng ZB, Yin Y, Wang M, Wei LB
The British journal of nutrition111(9)1536-48(2014 May)

Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca??/Calmodulin-dependent protein kinase II.
Ciani L, Boyle KA, Dickins E, Sahores M, Anane D, Lopes DM, Gibb AJ, Salinas PC
Proceedings of the National Academy of Sciences of the United States of America108(26)10732-7(2011 Jun)

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis.
Sahores M, Gibb A, Salinas PC
Development (Cambridge, England)137(13)2215-25(2010 Jul)

Data suggest that expression of Wnt7a can be regulated by dietary factors; here, ketoacid supplementation enhances muscle mass, in part, by upregulating Wnt7a signaling in skeletal muscle in rat model of chronic kidney disease on low-protein diet.
Title: Supplementation of ketoacids contributes to the up-regulation of the Wnt7a/Akt/p70S6K pathway and the down-regulation of apoptotic and ubiquitin-proteasome systems in the muscle of 5/6 nephrectomised rats.

CaMKII inhibition abolishes the effects of Wnt7a on spine growth and excitatory synaptic strength. These data indicate that Wnt7a signaling is critical to regulate spine growth and synaptic strength
Title: Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca??/Calmodulin-dependent protein kinase II.

Heterologous expression of Wnt1 enhanced [3H]thymidine incorporation and expression of cyclin D1 and cylin E in PC12 cells and opposite effects were observed in PC12 cells expressing Wnt7a
Title: Differential activation of the calcium/protein kinase C and the canonical beta-catenin pathway by Wnt1 and Wnt7a produces opposite effects on cell proliferation in PC12 cells.

Wnt-7a, but not Wnt-5a, increases neurotransmitter release in CA3-CA1 synapses by decreasing paired pulse facilitation and increasing the miniature excitatory post-synaptic currents frequency.
Title: Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons.

Wnt7a induces dissociation of the adenomatous polyposis coli protein from the beta-catenin cytoplasmic complex and the interaction of APC with alpha 7-nicotinic acetylcholine receptors in hippocampal neurons.
Title: Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons.