Rax cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rax
Entrez Gene ID	114213
Full Name	retina and anterior neural fold homeobox
Synonyms	Rx
General protein information	Preferred Names retina and anterior neural fold homeobox Names retinal homeobox protein Rx retina and anterior neural fold homeobox protein retinal homeobox transcription factor Rx/rax
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1
Summary	may play a role in glial cell development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053678.1	NP_446130.1	retinal homeobox protein Rx

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Rax	NP_446130.1
	RAX	XP_001087324.1
Xenopus tropicalis (tropical clawed frog)	rax	XP_002936715.1
Mus musculus (house mouse)	Rax	NP_038861.2
Pan troglodytes (chimpanzee)	RAX	XP_001142510.1
Danio rerio (zebrafish)	rx3	NP_571302.1
Homo sapiens (human)	RAX	NP_038463.2
Canis lupus familiaris (dog)	RAX	XP_852642.2
Bos taurus (cattle)	RAX	XP_003587831.1
Gallus gallus (chicken)	RAX	NP_001230653.1

Gene Ontology
Bibliography

Related articles in PubMed

Rax?: developmental and daily expression patterns in the rat pineal gland and retina.
Rohde K, Klein DC, M?ller M, Rath MF
Journal of neurochemistry118(6)999-1007(2011 Sep)

Expression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic rats.
Silva VA, Polesskaya A, Sousa TA, Corr?a VM, Andr? ND, Reis RI, Kettelhut IC, Harel-Bellan A, De Lucca FL
Molecular vision172228-40(2011)

Conditional alleles for activation and inactivation of the mouse Rx homeobox gene.
Voronina VA, Kozlov S, Mathers PH, Lewandoski M
Genesis (New York, N.Y. : 2000)41(4)160-4(2005 Apr)

The anophthalmic mutant of the mouse. II. An association of anophthalmia and polydactyly.
BECK SL
The Journal of heredity5479-83(1963 Mar-Apr)

Studies on an Anophthalmic Strain of Mice. IV. a Second Major Gene for Anophthalmia.
Chase HB
Genetics29(3)264-9(1944 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings are consistent with the evidence that Rax is of functional importance in eye development and suggest a role of Rax in the developing pineal gland
Title: Rax?: developmental and daily expression patterns in the rat pineal gland and retina.

RAX expression in the retina of diabetic rats may be indirectly regulated by miR-29b.
Title: Expression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic rats.

The following Rax gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rax cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10285	NM_053678.1 Latest version!	Rattus norvegicus retina and anterior neural fold homeobox (Rax), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rax ( NM_053678.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446130.1 Rattus norvegicus retina and anterior neural fold homeobox (Rax), mRNA.

Price & Availability↑

CloneID	ORa10285
Clone ID Related Accession (Same CDS sequence)	NM_053678.1
Accession Version	NM_053678.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	retinal homeobox protein Rx
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF135839.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCACCTGC CGGGGTGCCC GCCAGCCATG GCCGACGGGA GCTTCTCGCT CGCTGGCCAC 
CTGCTCCGCA GCCCGGGCGG GAGCACGTCG CGTTTGCACA GCATCGAAGC CATCCTGGGC 
TTTACCAAGG AAGACGGGAT CCTAGACACC TTTCCTGCAG AGAGGAGCTC CAGGGGCTCG 
AAGGAGCGGG ATCCCAGACT GGGTGCGCGG TCCGCCTGCC CCAAAGCTCC AGCCGGAGGC 
TCGGAGTCTT CCCCACCAGC AGCCCCGGGG CTCGTCCCGG AGTTCGAAGC TACTCGCCCC 
TGCTATCCCA AGGAGCAAGG AGAGGCACGG CCGAGCCCCG GACTGCCGGT TGGGCCAGCA 
GCGGGCGATT CGAAGCTGTC GGAGGAGGAG GAACCTCCCA AGAAGAAACA CAGGCGCAAC 
CGCACGACCT TCACCACGTA TCAACTGCAC GAGCTGGAAC GTGCCTTTGA GAAGTCCCAC 
TACCCCGACG TGTACAGCCG CGAAGAGTTG GCCGGCAAGG TTAACCTACC CGAGGTTCGG 
GTCCAGGTGT GGTTCCAGAA CCGTCGAGCC AAGTGGAGAC GCCAGGAGAA ACTAGAAGTG 
TCGTCCATGA AGCTGCAGGA CTCGCCCCTC CTCTCCTTCA GCCGGTCCCC ACCTTCCTCG 
GCACTGGCTC CGTTGGGCGG CCCGGGCAGC GGTAGCGGAC CTCCGGGGAG CGCCCTGCCG 
CTGGAGCCTT GGCTCGGGCC ACCGCTGCCC GGCGGAGGTG CCACAGCGCT GCAGAGCCTG 
CCAGGTTTCG GGCCGCCGGG GCAGGGTCTC CCGGCCAGCT ACACGCCGCC ACCGCCCTTC 
CTCAACTCCG CGCCCCTGGG TCCCGGTCTG CAGCAGCTCG GGCCGCCACC CGCGTACCCG 
TGCGCGCCGG CCTTCGGGGA CAAGTTCTCG CTGGAAGAGG CGTACCCACG CAACAGCAGC 
ATCGCCGCGC TGCGCCTGAA GGCCAAAGAG CACATCCAGG CCATCGGCAA GCCCTGGCAA 
GCCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446130.1
CDS	1..1029
Translation	MHLPGCPPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKEDGILDTFPAERSSRGSKERDPRLGARSACPKAPAGGSESSPPAAPGLVPEFEATRPCYPKEQGEARPSPGLPVGPAAGDSKLSEEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSSALAPLGGPGSGSGPPGSALPLEPWLGPPLPGGGATALQSLPGFGPPGQGLPASYTPPPPFLNSAPLGPGLQQLGPPPAYPCAPAFGDKFSLEEAYPRNSSIAALRLKAKEHIQAIGKPWQAL

Target ORF information:

RefSeq Version	NM_053678.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus retina and anterior neural fold homeobox (Rax), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053678.1

ORF Insert Sequence:

ATGCACCTGC CGGGGTGCCC GCCAGCCATG GCCGACGGGA GCTTCTCGCT CGCTGGCCAC 
CTGCTCCGCA GCCCGGGCGG GAGCACGTCG CGTTTGCACA GCATCGAAGC CATCCTGGGC 
TTTACCAAGG AAGACGGGAT CCTAGACACC TTTCCTGCAG AGAGGAGCTC CAGGGGCTCG 
AAGGAGCGGG ATCCCAGACT GGGTGCGCGG TCCGCCTGCC CCAAAGCTCC AGCCGGAGGC 
TCGGAGTCTT CCCCACCAGC AGCCCCGGGG CTCGTCCCGG AGTTCGAAGC TACTCGCCCC 
TGCTATCCCA AGGAGCAAGG AGAGGCACGG CCGAGCCCCG GACTGCCGGT TGGGCCAGCA 
GCGGGCGATT CGAAGCTGTC GGAGGAGGAG GAACCTCCCA AGAAGAAACA CAGGCGCAAC 
CGCACGACCT TCACCACGTA TCAACTGCAC GAGCTGGAAC GTGCCTTTGA GAAGTCCCAC 
TACCCCGACG TGTACAGCCG CGAAGAGTTG GCCGGCAAGG TTAACCTACC CGAGGTTCGG 
GTCCAGGTGT GGTTCCAGAA CCGTCGAGCC AAGTGGAGAC GCCAGGAGAA ACTAGAAGTG 
TCGTCCATGA AGCTGCAGGA CTCGCCCCTC CTCTCCTTCA GCCGGTCCCC ACCTTCCTCG 
GCACTGGCTC CGTTGGGCGG CCCGGGCAGC GGTAGCGGAC CTCCGGGGAG CGCCCTGCCG 
CTGGAGCCTT GGCTCGGGCC ACCGCTGCCC GGCGGAGGTG CCACAGCGCT GCAGAGCCTG 
CCAGGTTTCG GGCCGCCGGG GCAGGGTCTC CCGGCCAGCT ACACGCCGCC ACCGCCCTTC 
CTCAACTCCG CGCCCCTGGG TCCCGGTCTG CAGCAGCTCG GGCCGCCACC CGCGTACCCG 
TGCGCGCCGG CCTTCGGGGA CAAGTTCTCG CTGGAAGAGG CGTACCCACG CAACAGCAGC 
ATCGCCGCGC TGCGCCTGAA GGCCAAAGAG CACATCCAGG CCATCGGCAA GCCCTGGCAA 
GCCCTCTAG