Cdh23 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdh23
Entrez Gene ID	114102
Full Name	cadherin-related 23
Synonyms	W
General protein information	Preferred Names cadherin-related 23 Names cadherin-23 Waltzing cadherin 23 (otocadherin) otocadherin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20q11
Summary	may mediate calcium-dependent cell-cell adhesion; mutations in human homolog cause Usher syndrome type 1D [RGD, Jun 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053644.1	NP_446096.1	cadherin-23 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CDH23	XP_507839.3
Mus musculus (house mouse)	Cdh23	NP_075859.2
Gallus gallus (chicken)	CDH23	XP_421595.3
Rattus norvegicus (Norway rat)	Cdh23	NP_446096.1
Xenopus tropicalis (tropical clawed frog)	cdh23	XP_002939565.2
	CDH23	XP_002805748.1
Bos taurus (cattle)	CDH23	NP_001178135.1
Homo sapiens (human)	CDH23	NP_071407.4
Canis lupus familiaris (dog)	CDH23	XP_003434519.1
Danio rerio (zebrafish)	cdh23	NP_999974.1

Gene Ontology
Bibliography

Related articles in PubMed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.
Kamiya K, Michel V, Giraudet F, Riederer B, Foucher I, Papal S, Perfettini I, Le Gal S, Verpy E, Xia W, Seidler U, Georgescu MM, Avan P, El-Amraoui A, Petit C
Proceedings of the National Academy of Sciences of the United States of America111(25)9307-12(2014 Jun)

Cyclic nucleotide-gated channel ?-3 (CNGA3) interacts with stereocilia tip-link cadherin 23 + exon 68 or alternatively with myosin VIIa, two proteins required for hair cell mechanotransduction.
Selvakumar D, Drescher MJ, Drescher DG
The Journal of biological chemistry288(10)7215-29(2013 Mar)

TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells.
Xiong W, Grillet N, Elledge HM, Wagner TF, Zhao B, Johnson KR, Kazmierczak P, M?ller U
Cell151(6)1283-95(2012 Dec)

Association of cadherin23 single nucleotide polymorphism with age-related hearing impairment in Han Chinese.
Hwang JH, Liu KS, Wu CC, Liu TC
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery147(3)531-4(2012 Sep)

Sensing sound: molecules that orchestrate mechanotransduction by hair cells.
Kazmierczak P, M?ller U
Trends in neurosciences35(4)220-9(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that CNGA3 interacts with cadherin 23 and with cadherin 23 binding partner, myosin VIIa.
Title: Cyclic nucleotide-gated channel ?-3 (CNGA3) interacts with stereocilia tip-link cadherin 23 + exon 68 or alternatively with myosin VIIa, two proteins required for hair cell mechanotransduction.

Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells
Title: Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells.

The following Cdh23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdh23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12799	NM_053644.1 Latest version!	Rattus norvegicus cadherin-related 23 (Cdh23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdh23 ( NM_053644.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446096.1 Rattus norvegicus cadherin-related 23 (Cdh23), mRNA.

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CloneID	ORa12799
Clone ID Related Accession (Same CDS sequence)	NM_053644.1
Accession Version	NM_053644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 9954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	cadherin-23 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB053447.1. On Jan 12, 2005 this sequence version replaced XM_346602.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB053447.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689604, SAMN00632256 [ECO:0000350] ##Evidence-Data-END##

ATGAGGCACC CCCCTGTCAC TTGGTGTGCC ATGCTCTGGC TTCTCATGCT GGTGTCCGGA 
TCCTGGGGCC AGGTGAACCG ACTACCTTTT TTCACCAATC ACTTCTTTGA CACGTACCTG 
CTCATCAGTG AAGACACTCC TGTGGGTTCT TCTGTGACCC AGTTGCTGGC CCGAGACATG 
GACAATGACC CCTTGGTGTT CGGCGTGTCT GGGGAGGAGG CCTCCCGCTT CTTTGCCGTG 
GAGCCTGACA CGGGTGTGGT GTGGCTCCGG CAGCCACTGG ACAGAGAGAC TAAGTCTGAG 
TTCACAGTGG AGTTCTCCGT CAGTGACCAC CAAGGGGTGA TCACAAGGAA GGTGAATATC 
CAAGTTGGAG ACGTGAACGA CAATGCACCC ACATTCCACA ACCAGCCCTA CAGCGTGCGC 
ATCCCTGAAA ACACACCAGT GGGGACACCC ATCTTCATCG TCAACGCCAC TGATCCTGAC 
CTGGGCGCAG GGGGCAGTGT CCTCTACTCC TTCCAGCCCC CCTCTCAGTT CTTCGCCATC 
GACAGTGCCC GAGGCATAGT CACCGTGATC CGGGAGCTGG ACTATGAGGT CACGCAGGCG 
TACCAGCTCA CAGTCAATGC CACGGATCAA GACAAGACCA GACCTCTGTC TACATTAGCC 
AACCTGGCCA TCATCATCAC GGACGTACAA GACATGGACC CCATCTTCAT CAATCTGCCC 
TACAGTACCA ACATCTATGA GCACTCTCCC CCGGGCACGA CTGTGCGGGT GATCACTGCT 
GTGGATCAGG ATAAGGGACG GCCCCGGGGG ATTGGCTACA CTATTGTCTC AGGGAATACG 
AACAGCATCT TTGCCCTGGA CTACATCAGC GGGGCTCTCA CCCTGAATGG CCTGCTGGAC 
CGGGAGAACC CCCTGTACAG CCACGGCTTC ATCCTGACGG TGAAGGGCAC TGAGCTGAAT 
GATGATCGTA GTCCGTCTGA CGCCACCGTC ACCACGACCT TCAACATCCT GGTTATCGAC 
ATCAATGACA ATGCCCCGGA GTTCAACAGC TCTGAGTACA GCGTGGCCAT TACTGAGCTG 
GCACAGGTCG GCTTTGCCCT CCCTCTCTTC ATCCAGGTGG TGGACAAGGA TGAGGGTCTA 
AACAGCATGT TCGAGGTGTA CCTGGTGGGC AACAACTCCC ACCACTTCAT CATCTCCCCA 
ACCTCCGTCC AGGGGAAAGC AGACATCCGC ATCCGAGTGG CAATCCCACT GGACTACGAG 
ACCGTGGACA GATACGACTT TGACCTCTTT GCCAACGAGA GCGTACCCGA CCACGTGGGC 
TACGCCAAGG TGAAGATTAC GCTCATTAAT GAAAATGACA ACCGGCCCAT CTTCAGCCAG 
CCCCTCTACA ATGTCAGCCT GTATGAAAAC ATCACCGTGG GGACCTCCGT GCTGACAGTC 
CTGGCAACAG ACAATGACGT GGGCACTTTT GGGGAAGTCA ACTACTTCTT CAGTGATGAC 
CCCGACAGGT TCTCACTGGA CAAGGACACA GGCCTCATCA TGCTTATAGC CCGGCTGGAC 
TATGAGCTTA TCCAGCGTTT CACCTTGACT GTCATTGCCC GGGATGGTGG CGGTGAGGAG 
ACCACAGGCC GGGTCCGGAT CAATGTGCTG GATGTCAACG ACAATGTGCC CACCTTCCAG 
AAGGATGCCT ACGTGGGTGC TCTGAGGGAG AATGAGCCAT CTGTCACACA GCTGGTGCGG 
CTCAGGGCAA CAGATGAAGA CTCCCCTCCC AACAACCTGA TCACCTACAG CATCGTCAAC 
GCGTCCGCCT TCGGCAGCTA CTTTGACATC AGTGTGTATG AAGGCTATGG AGTGATCAGT 
GTGAGCCGCC CACTGGATTA TGAACAGATA CCCAATGGGC TGATATACCT AACCGTCATG 
GCCAAGGATG CTGGCAACCC TCCGCTCTAC AGCACCGTCC CTGTCACCAT TGAGGTGTTT 
GATGAGAACG ACAACCCTCC CACCTTCAGC AAGCCTGCCT ACTTCGTGTC TGTGGTGGAG 
AACATCATGG CAGGAGCCAC AGTGTTGTTC CTAAATGCCA CGGACCTGGA CCGCTCCCGG 
GAGTATGGGC AGGAGTCTAT CATCTATTCG CTGGAGGGCT CCTCACAGTT CCGCATCAAT 
GCCCGCTCTG GAGAAATCAC CACCACGTCT CTGCTGGACC GAGAGACCAA AGCTGAATAC 
ATACTCATTG TGCGTGCTGT GGATGGGGGT GTGGGCCACA ACCAGAAAAC TGGCATTGCC 
ACAGTGAATG TCACCCTCCT AGACATCAAT GACAACCACC CCACCTGGAA GGATGCTCCC 
TACTACATCA ACCTGGTGGA GATGACGCCT CCAGACTCTG ATGTGACCAC GGTGGTAGCT 
GTGGACCCAG ATCTGGGGAA GAATGGCACC CTGGTGTACA GCATCCAGCC CCCCAACAAG 
TTCTATAGTC TGAACAGCAC CACAGGCAAG ATCCGCACCA CCCACGTCAT GCTGGACCGA 
GAGAACCCTG ACCCCGTGGA GGCGGAGCTC ATGCGCAAGA TCATTGTCTC TGTCACGGAC 
TGTGGTAGAC CCCCCCTGAA GGCCACCAGC AGTGCCACAG TCTTTGTGAA CCTCTTGGAT 
CTCAATGACA ACGACCCCAC CTTCCAGAAC CTGCCTTTTG TGGCTGAGGT TCTTGAGGGC 
ACCCCTGCAG GGGTCTCTGT CTACCAAGTG GTGGCCATCG ATCTGGATGA GGGCCTGAAT 
GGACTGGTGT CCTATCGCAT GCAAGTGGGC ATGCCCCGCA TGGACTTTGT CATCAACAGC 
ACCAGTGGTG TGGTCACGAC CACAGCCGAG TTGGACCGGG AGCGCATCGC CGAGTACCAG 
CTGCGGGTGG TGGCCAGCGA TGCGGGCACA CCTACCAAGA GCTCCACCAG CACCCTCACC 
ATCCGCGTGT TGGATGTGAA CGATGAGACG CCCACCTTCT TCCCTGCCGT GTACAACGTG 
TCCGTGTCTG AGGATGTTCC CCGTGAGTTC CGTGTGGTCT GGCTGAACTG CACAGACAAT 
GACGTCGGTC TCAATGCGGA ACTCAGCTAC TTCATCACAG CGGGAAATGT GGACGGGAAG 
TTTAGTGTGG GCTACCGTGA TGCCGTGGTG AGAACCGTGG TCGGCCTGGA CCGTGAGACC 
ACAGCTGCGT ACACACTGGT GCTGGAGGCT ATCGACAATG TCCCTGTAGG CAAGCGGCGC 
ACAGGTACGG CCACCGTGTT TGTCACAGTT CTGGATGTGA ACGACAACCG GCCCATCTTC 
CTGCAAAGCA GCTATGAGGC CAGTGTCCCA GAAGACATCC CCGAGGGCCA CAGCATTGTG 
CAGCTGAAAG CCACAGATGC AGACGAGGGC GAGTTTGGAC GTGTCTGGTA CCGCATCCTC 
CATGGTAACC ATGGCAACAA CTTCCGCCTC CACGTCAGCA GCGGGCTCCT GGTGCGAGGC 
CCAAGGCCCC TGGACAGGGA GCGAAACTCG TCCCATGTGC TGATGGCAGA AGCCTACAAC 
CACGACCTGG GGCCCATGCG GAGCTCGGTC AGGGTGATCG TGTATGTGGA AGATGTCAAC 
GATGAGGCCC CTGTGTTCAC ACAGCAGCAG TACAATCGCC TGGGCCTTCG AGAGACAGCA 
GGCATCGGCA CCTCAGTCAT CGTTGTCCGA GCCACCGACA GAGACACTGG GGACGGTGGC 
CTGGTGAACT ACCGCATCCT GTCGGGCGCA GAGGGCAAGT TTGAGATTGA CGAGAGCACA 
GGGCTCATCG TGACGGTTGA CTATCTGGAC TACGAGACCA AGACCAGCTA TCTGATGAAC 
GTGTCAGCCA CAGACGGTGC ACCCCCCTTC AACCAGGGCT TCTGCAGCGT CTACGTGACA 
CTTCTCAACG AGCTGGATGA GGCTGTTCAG TTCTCCAATG CCTCCTATGA GGCAGTCATC 
ATGGAGAATC TGGCTCTGGG GACCGAGATC GTGCGGGTGC AAGCCTATTC CATTGATAAC 
CTCAATCAAA TCACCTACCG CTTTGACGCC TATACCAGCG CCCAGGCCAA AGCCCTCTTC 
AAGATAGATG CCATCACGGG CGTGATCACA GTCAAAGGCT TGGTCGACAG GGAGAAGGGC 
GACTTCTACA CATTGACGGT CGTGGCAGAT GATGGTGGCC CCAAGGTGGA CTCTACTGTG 
AAGGTCTACG TCACTGTTCT GGATGAAAAT GATAACAGCC CACGCTTTGA CTTCACCTCT 
GATTCGGCCA TCAGTGTGCC TGAGGACTGC CCTGTAGGCC AACGAGTAGC CACTGTCAAG 
GCCCGGGACC CTGATGCTGG CAGCAACGGT CAGGTGGTCT TCTCCCTGGC CTCCGGTAAC 
ATTGCTGGGG CCTTTGAGAT TATCACCAGC AATGACTCCA TTGGTGAAGT GTTTGTGGCT 
AAGCCCCTGG ACAGGGAGGA ACTGGACCAC TACATCCTCA AGATTGTAGC TTCTGACCGT 
GGCACTCCTC CACGGAAGAA AGACCACATC TTACAGGTGA CCATTCTGGA TGTCAATGAC 
AACCCTCCAG TGATTGAGAG CCCCTTTGGG TACAACGTCA GTGTGAATGA GAATGTGGGT 
GGAGGCACCT CAGTAGTCCA GGTGAGAGCC ACCGACCGTG ACATCGGGAT CAACAGCGTC 
CTGTCCTATT ATATCACGGA GGGCAATGAG GACATGACTT TCCGTATGGA CCGCATCAGC 
GGTGAGATTG CTACACGGCC TGCTCCACCC GACCGTGAGC GCCAGAACTT CTACCACCTG 
GTGGTCACTG TGGAAGACGA GGGCACCCCC ACACTATCGG CTACCACCCA TGTGTACGTG 
ACTATCGTGG ACGAGAATGA CAATGCTCCT GTGTTCCAGC AGCCACATTA TGAGGTGGTG 
CTGGACGAGG GCCCGGACAC AGTCAACACC AGCCTCATCA CCGTCCAGGC GCTGGACCTG 
GATGAGGGCC CGAATGGCAC TGTTACCTAT GCCATTGTGG CAGGCAATAT CATCAATACC 
TTCCGAATCA ACAGGCGCAC GGGTGTCATT ACTGCTGCCA AGGAGCTAGA CTATGAGATC 
AGTCATGGCC GCTATACCCT GATTGTCACT GCCACAGACC AGTGTCCCAT CTTGTCCCAC 
CGCCTCACCT CTACTACCAC AGTGCTCGTG AACGTGAATG ACATCAATGA CAATGTGCCC 
ACTTTCCCTC GGGACTATGA AGGACCATTC GATGTCACTG AGGGCCAACC AGGGCCCAGA 
GTGTGGACAT TCCTGGCCCA TGACCGGGAC TCCGGTCCCA ATGGGCAGGT GGAGTACAGT 
GTTGTGGATG GAGACCCACT GGGGGAGTTT GTGATCTCTC CTGTGGAGGG TGTGCTGAGG 
GTCCGGAAGG ATGTAGAACT GGATCGGGAG ACCATCGCCT TCTACAATCT GACCATCTGT 
GCCCGAGACA GGGGGGTGCC GCCACTCAGC TCCACGATGC TGGTGGGAAT CCGAGTGCTG 
GACATCAATG ACAATGACCC GGTGCTGTTG AATCTTCCCA TGAACATCAC CATCAGTGAG 
AACAGCCCGG TCTCCAGCTT CGTCGCCCAC GTCCTGGCCA GCGACGCTGA CAGTGGCTGC 
AATGCCCTGC TCACCTTCAA CATCACCGCT GGCAACCGGG AGCGGGCCTT CTTCATCAAT 
GCCACGACAG GGATCGTCAC TGTCAACCGG CCCCTGGACC GAGAGCGCAT CCCAGAATAC 
AGGCTGACCG TTTCTGTAAA GGACAACCCA GAGAACCCAC GCATAGCCAG GAAGGATTTT 
GACTTACTGC TGGTCTCTCT GGCTGATGAA AATGACAACC ACCCCCTCTT CACTGAGGGC 
ACGTACCAGG CCGAGGTGAT GGAGAACTCT CCTGCTGGGA CACCTCTCAC CGTGCTCAAT 
GGACCTATCC TGGCCCTGGA TGCTGATGAA GATGTGTACG CTGTAGTCAC GTATCAACTC 
CTGGGCACTC ACAGCGACCT GTTTGTTATT GACAATAGCA CGGGCGTGGT GACTGTGAGG 
TCCGGGGTCA TCATCGACCG GGAGGCCTTC TCACCCCCAT TCCTGGAGTT GCTGCTGTTG 
GCTGAGGACG TGGGACAACT CAATGGCACG GCCTACCTGT TCATCACTAT CCTAGATGAC 
AATGACAACT GGCCCACCTT CAGTCCTCCT GCTTACACTG TCCACCTGCT GGAGAACTGC 
CCACCAGGAT TCTCAGTCCT TCAGATCACA GCCACAGATG AGGACAGCGG CCTCAATGGG 
GAGCTGGTCT ACCGAATAGA AGCCGGGGCT CAGGACCGCT TCCTCATCCA TCCAGTCACA 
GGAGTCATCC GTGTTGGCAA TGCCACCATT GACAGAGAAG AGCAGGAATC CTACAGGCTG 
ACGGTGGTGG CCACCGACCG GGGCACTGTT CCCTTGTCGG GCACAGCCAC CGTCACCATC 
CTGATCGATG ACATCAATGA CTCCCGCCCT GAGTTCCTCA ACCCTATCCA GACAGTGAGC 
GTGCTGGAAT CCACAGAGCC AGGCACTGTC ATTGCTAACG TCACTGCCAT CGACCTCGAC 
CTCAACCCCA AACTGGAGTA TCACATCCTT AGCATCGTGG CCAAGGACGA CACTGACCGC 
CTGGTGCCTG ACCAGGAAGA TGCCTTTGCT GTGAATATCA ATACAGGGTC CGTGATAGTG 
AAGTCCCCTC TGAACCGCGA GCTGGTTGCT ACCTATGAGG TCACGCTCTC AGTAATCGAC 
AATGCCAGCG ACCTCCCAGA GCGTTCTGTC AGTGTGCCAA ACGCCAAGCT CACGGTCAAC 
ATCCTGGATG TCAATGACAA TACACCGCAG TTCAAGCCCT TTGGAATCAC CTACTACACA 
GAGCGGGTCC TGGAGGGGGC CACCCCAGGC ACAACGCTCA TTGCTGTGGC CGCCGTTGAT 
CCCGACAAGG GCCTTAACGG GCTGATCACC TACACCCTGC TAGACCTCAT ACCCCCAGGC 
TATGTCCAGC TCGAAGACTC TTCAGCAGGG AAGGTCATCG CCAACCGTAC GGTGGACTAC 
GAGGAGGTTC ACTGGCTTAA CTTCACCGTG AGGGCCTCAG ACAATGGGTC CCCACCCCGG 
GCAGCTGAGA TCCCTGTCTA CCTGGAAATT GTAGACATTA ATGACAACAA CCCCATCTTT 
GATCAGCTCT CCTACCAGGA GGCTGTTTTT GAGGATGTAG CTGTGGGCAC GGTCATCCTG 
AGGGTTACAG CTACGGATGC TGACTCAGGC AACTTTGCTC TCATCGAGTA CAGCCTGGTG 
GATGGAGAGG GCAAATTTGC CATCAACCCC AACACTGGTG ACATCTATGT GCTGTCCTCT 
CTGGACCGAG AGAAGAAGGA CCACTACATC CTAACTGCTT TGGCCAAAGA CAACCCTGGC 
GATGTGGCCA GTAACCGTCG CGAGAACTCG GTGCAGGTGG TGATCCGAGT ACTTGATGTC 
AATGACTGTC GGCCTCAGTT CTCCAAGCCA CAGTTCAGCA CAAGTGTGTA CGAGAATGAG 
CCAGCAGGTA CTTCAGTCAT CACCATGCTG GCCACTGACC AGGACGAGGG CTCTAATGGC 
CAGCTGACCT ACTCTCTTGA GGGTCCCGGA ATGGAGGCTT TCTCTGTGGA CATGGACTCG 
GGCCTGGTGA CCACGCAGCG GCCACTACAG TCCTATGAGA GGTTCAACCT GACCGTAGTG 
GCTACAGATG GTGGGGAGCC CCCACTCTGG GGCACCACAA TGCTCCTAGT GGAAGTCATC 
GATGTCAATG ACAACCGCCC CGTCTTCGTG CGCCCACCCA ATGGCACCAT TCTGCACATC 
AAAGAGGAGA TCCCGCTACG TTCCAATGTG TATGAAGTCT ATGCTACAGA CAAGGATGAA 
GGCCTCAACG GGGCAGTACG CTACAGCTTC CTGAAGTCAA CAGGCAACCG TGACTGGGAG 
TACTTCACCA TCGACCCAAT TAGTGGCCTC ATCCAGACAG CGCAGCGCCT GGACCGTGAG 
AAGCAGGCAG TGTACAGTCT CATCTTGGTG GCCAGCGACC TGGGCCAGCC AGTGCCATAC 
GAGACGATGC AGCCATTGCA GGTGGCCCTG GAGGACATCG ATGACAATGA GCCCCTCTTT 
GTGAGGCCTC CTAAGGGAAG CCCTCAGTAC CAACTGCTAA CAGTGCCTGA ACACTCCCCC 
CGTGGCACCC TTGTGGGCAA CGTGACAGGC GCGGTGGACG CAGATGAAGG TCCCAATGCC 
ATTGTGTACT ACTTCATTGC AGCTGGTAAC GAGGACAAGA ATTTCCACCT ACAACCTGAC 
GGACGCCTGC TAGTGCTTAG AGACCTGGAT CGGGAGACGG AAGCCATCTT CTCCTTCATT 
GTCAAGGCGT CCAGCAATCG CAGTTGGACC CCTCCCCGAG GACCCTCCCC AGCCCTCGAT 
CTGCTGACCG ATCTCACCCT GCAGGAGGTG CGCGTTGTGC TGGAGGACAT CAATGACCAA 
CCGCCACGCT TCACCAAGGC TGAGTATACC GCAGGAGTGG CCACCGACGC CAAGGTAGGC 
TCGGAGTTGA TCCAGGTGCT GGCCCTGGAT GCAGACATTG GCAACAACAG CCTGGTCTTC 
TATGGCATTC TGGCTATCCA CTACTTCCGG GCCCTGGCCA ATGACTCCGA GGATGTGGGT 
CAGGTCTTCA CCATGGGGAG TGTGGACGGC ATCCTGCGTA CCTTTGACCT CTTCATGGCC 
TACAGCCCTG GCTACTTTGT GGTAGACATC GTGGCCCGAG ACCTGGCCGG TCACAACGAT 
ACAGCCATCA TTGGCATCTA CATCCTGAGG GATGACCAGC GCGTTAAGAT AGTCATCAAC 
GAGATCCCAG ACCGTGTGCG TGGCTTTGAG GAGGAGTTCA TTCGCCTGCT GTCCAACATC 
ACAGGCGCCA TCGTCAACAC TGATGACGTG CAGTTCCATG TGGATATGAA AGGAAGAGTG 
AATTTTGCAC AGACAGAGCT GCTCATCCAC GTGGTCAACC GCGACACGAA CCGCATCCTG 
GATGTGGACA GGGTCATCCA GATGATTGAT GAGAACAAGG AACAACTTCG AAACCTCTTC 
CGGAACTACA ATGTACTGGA CGTGCAGCCT GCCATCTCTG TCCAGCTGCC AGACGACATG 
TCTGCCCTGC AGATGGCCAT CATTGTCCTG GCCATCCTTC TCTTCTTGGC TGCCATGCTC 
TTTGTCCTCA TGAACTGGTA CTACAGGACC ATACACAAGA GAAAGCTAAA GGCCATTGTG 
GCTGGTTCTG CTGGGAACCG TGGCTTCATT GACATCATGG ACATGCCCAA TACCAACAAA 
TACTCCTTCG ATGGAGCCAA CCCTGTGTGG CTGGACCCCT TCTGCCGGAA CCTGGAGCTG 
GCTGCACAGG CTGAACACGA GGATGACCTC CCTGAGAACC TGAGTGAGAT CGCAGACCTG 
TGGAACAGCC CCACCCGCAC CCATGGAACT TTTGGACGTG AGCCCGCGGC AGTCAAACCT 
GAAGATGACA GATACCTGCG GGCAGCCATC CAGGAGTATG ACAACATAGC CAAGCTGGGT 
CAGATCATTC GAGAAGGACC TATTAAGCTG ATCCACACTG ACCTGGAGGA GGAGCCTGGC 
GACCACAGCC CAGGCCAGGG CAGCCTCCGT TTCCGACACA AGCCACCCAC GGAACTCAAG 
GGGCCAGATG GAATCCACAT AGTTCACGGT AGCACGGGCA CACTGCTGGC CACTGATCTC 
AACAGCTTGC CTGAGGACGA CCAGAAGGGG CTAGACCGCT CACTGGAGAC TCTGACAGCC 
TCTGAAGCCA CTGCCTTTGA ACGCAATGCC CGCACCGAGT CGGCCAAGTC CACCCCTCTG 
CATAAGCTTC GAGACGTCAT CATGGAGAGC CCCCTGGAAA TCACGGAACT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446096.1
CDS	348..10301
Translation	MRHPPVTWCAMLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRSPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNLITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKAEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGKNGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGMPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITAGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNVPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRLHVSSGLLVRGPRPLDRERNSSHVLMAEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDGAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYVTVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIITSNDSIGEVFVAKPLDREELDHYILKIVASDRGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNTSLITVQALDLDEGPNGTVTYAIVAGNIINTFRINRRTGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGVIIDREAFSPPFLELLLLAEDVGQLNGTAYLFITILDDNDNWPTFSPPAYTVHLLENCPPGFSVLQITATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTATVTILIDDINDSRPEFLNPIQTVSVLESTEPGTVIANVTAIDLDLNPKLEYHILSIVAKDDTDRLVPDQEDAFAVNINTGSVIVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLIPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQLSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVRYSFLKSTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDRETEAIFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDMKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVQLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTIHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPEDDRYLRAAIQEYDNIAKLGQIIREGPIKLIHTDLEEEPGDHSPGQGSLRFRHKPPTELKGPDGIHIVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL

Target ORF information:

RefSeq Version	NM_053644.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cadherin-related 23 (Cdh23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053644.1

ORF Insert Sequence:

ATGAGGCACC CCCCTGTCAC TTGGTGTGCC ATGCTCTGGC TTCTCATGCT GGTGTCCGGA 
TCCTGGGGCC AGGTGAACCG ACTACCTTTT TTCACCAATC ACTTCTTTGA CACGTACCTG 
CTCATCAGTG AAGACACTCC TGTGGGTTCT TCTGTGACCC AGTTGCTGGC CCGAGACATG 
GACAATGACC CCTTGGTGTT CGGCGTGTCT GGGGAGGAGG CCTCCCGCTT CTTTGCCGTG 
GAGCCTGACA CGGGTGTGGT GTGGCTCCGG CAGCCACTGG ACAGAGAGAC TAAGTCTGAG 
TTCACAGTGG AGTTCTCCGT CAGTGACCAC CAAGGGGTGA TCACAAGGAA GGTGAATATC 
CAAGTTGGAG ACGTGAACGA CAATGCACCC ACATTCCACA ACCAGCCCTA CAGCGTGCGC 
ATCCCTGAAA ACACACCAGT GGGGACACCC ATCTTCATCG TCAACGCCAC TGATCCTGAC 
CTGGGCGCAG GGGGCAGTGT CCTCTACTCC TTCCAGCCCC CCTCTCAGTT CTTCGCCATC 
GACAGTGCCC GAGGCATAGT CACCGTGATC CGGGAGCTGG ACTATGAGGT CACGCAGGCG 
TACCAGCTCA CAGTCAATGC CACGGATCAA GACAAGACCA GACCTCTGTC TACATTAGCC 
AACCTGGCCA TCATCATCAC GGACGTACAA GACATGGACC CCATCTTCAT CAATCTGCCC 
TACAGTACCA ACATCTATGA GCACTCTCCC CCGGGCACGA CTGTGCGGGT GATCACTGCT 
GTGGATCAGG ATAAGGGACG GCCCCGGGGG ATTGGCTACA CTATTGTCTC AGGGAATACG 
AACAGCATCT TTGCCCTGGA CTACATCAGC GGGGCTCTCA CCCTGAATGG CCTGCTGGAC 
CGGGAGAACC CCCTGTACAG CCACGGCTTC ATCCTGACGG TGAAGGGCAC TGAGCTGAAT 
GATGATCGTA GTCCGTCTGA CGCCACCGTC ACCACGACCT TCAACATCCT GGTTATCGAC 
ATCAATGACA ATGCCCCGGA GTTCAACAGC TCTGAGTACA GCGTGGCCAT TACTGAGCTG 
GCACAGGTCG GCTTTGCCCT CCCTCTCTTC ATCCAGGTGG TGGACAAGGA TGAGGGTCTA 
AACAGCATGT TCGAGGTGTA CCTGGTGGGC AACAACTCCC ACCACTTCAT CATCTCCCCA 
ACCTCCGTCC AGGGGAAAGC AGACATCCGC ATCCGAGTGG CAATCCCACT GGACTACGAG 
ACCGTGGACA GATACGACTT TGACCTCTTT GCCAACGAGA GCGTACCCGA CCACGTGGGC 
TACGCCAAGG TGAAGATTAC GCTCATTAAT GAAAATGACA ACCGGCCCAT CTTCAGCCAG 
CCCCTCTACA ATGTCAGCCT GTATGAAAAC ATCACCGTGG GGACCTCCGT GCTGACAGTC 
CTGGCAACAG ACAATGACGT GGGCACTTTT GGGGAAGTCA ACTACTTCTT CAGTGATGAC 
CCCGACAGGT TCTCACTGGA CAAGGACACA GGCCTCATCA TGCTTATAGC CCGGCTGGAC 
TATGAGCTTA TCCAGCGTTT CACCTTGACT GTCATTGCCC GGGATGGTGG CGGTGAGGAG 
ACCACAGGCC GGGTCCGGAT CAATGTGCTG GATGTCAACG ACAATGTGCC CACCTTCCAG 
AAGGATGCCT ACGTGGGTGC TCTGAGGGAG AATGAGCCAT CTGTCACACA GCTGGTGCGG 
CTCAGGGCAA CAGATGAAGA CTCCCCTCCC AACAACCTGA TCACCTACAG CATCGTCAAC 
GCGTCCGCCT TCGGCAGCTA CTTTGACATC AGTGTGTATG AAGGCTATGG AGTGATCAGT 
GTGAGCCGCC CACTGGATTA TGAACAGATA CCCAATGGGC TGATATACCT AACCGTCATG 
GCCAAGGATG CTGGCAACCC TCCGCTCTAC AGCACCGTCC CTGTCACCAT TGAGGTGTTT 
GATGAGAACG ACAACCCTCC CACCTTCAGC AAGCCTGCCT ACTTCGTGTC TGTGGTGGAG 
AACATCATGG CAGGAGCCAC AGTGTTGTTC CTAAATGCCA CGGACCTGGA CCGCTCCCGG 
GAGTATGGGC AGGAGTCTAT CATCTATTCG CTGGAGGGCT CCTCACAGTT CCGCATCAAT 
GCCCGCTCTG GAGAAATCAC CACCACGTCT CTGCTGGACC GAGAGACCAA AGCTGAATAC 
ATACTCATTG TGCGTGCTGT GGATGGGGGT GTGGGCCACA ACCAGAAAAC TGGCATTGCC 
ACAGTGAATG TCACCCTCCT AGACATCAAT GACAACCACC CCACCTGGAA GGATGCTCCC 
TACTACATCA ACCTGGTGGA GATGACGCCT CCAGACTCTG ATGTGACCAC GGTGGTAGCT 
GTGGACCCAG ATCTGGGGAA GAATGGCACC CTGGTGTACA GCATCCAGCC CCCCAACAAG 
TTCTATAGTC TGAACAGCAC CACAGGCAAG ATCCGCACCA CCCACGTCAT GCTGGACCGA 
GAGAACCCTG ACCCCGTGGA GGCGGAGCTC ATGCGCAAGA TCATTGTCTC TGTCACGGAC 
TGTGGTAGAC CCCCCCTGAA GGCCACCAGC AGTGCCACAG TCTTTGTGAA CCTCTTGGAT 
CTCAATGACA ACGACCCCAC CTTCCAGAAC CTGCCTTTTG TGGCTGAGGT TCTTGAGGGC 
ACCCCTGCAG GGGTCTCTGT CTACCAAGTG GTGGCCATCG ATCTGGATGA GGGCCTGAAT 
GGACTGGTGT CCTATCGCAT GCAAGTGGGC ATGCCCCGCA TGGACTTTGT CATCAACAGC 
ACCAGTGGTG TGGTCACGAC CACAGCCGAG TTGGACCGGG AGCGCATCGC CGAGTACCAG 
CTGCGGGTGG TGGCCAGCGA TGCGGGCACA CCTACCAAGA GCTCCACCAG CACCCTCACC 
ATCCGCGTGT TGGATGTGAA CGATGAGACG CCCACCTTCT TCCCTGCCGT GTACAACGTG 
TCCGTGTCTG AGGATGTTCC CCGTGAGTTC CGTGTGGTCT GGCTGAACTG CACAGACAAT 
GACGTCGGTC TCAATGCGGA ACTCAGCTAC TTCATCACAG CGGGAAATGT GGACGGGAAG 
TTTAGTGTGG GCTACCGTGA TGCCGTGGTG AGAACCGTGG TCGGCCTGGA CCGTGAGACC 
ACAGCTGCGT ACACACTGGT GCTGGAGGCT ATCGACAATG TCCCTGTAGG CAAGCGGCGC 
ACAGGTACGG CCACCGTGTT TGTCACAGTT CTGGATGTGA ACGACAACCG GCCCATCTTC 
CTGCAAAGCA GCTATGAGGC CAGTGTCCCA GAAGACATCC CCGAGGGCCA CAGCATTGTG 
CAGCTGAAAG CCACAGATGC AGACGAGGGC GAGTTTGGAC GTGTCTGGTA CCGCATCCTC 
CATGGTAACC ATGGCAACAA CTTCCGCCTC CACGTCAGCA GCGGGCTCCT GGTGCGAGGC 
CCAAGGCCCC TGGACAGGGA GCGAAACTCG TCCCATGTGC TGATGGCAGA AGCCTACAAC 
CACGACCTGG GGCCCATGCG GAGCTCGGTC AGGGTGATCG TGTATGTGGA AGATGTCAAC 
GATGAGGCCC CTGTGTTCAC ACAGCAGCAG TACAATCGCC TGGGCCTTCG AGAGACAGCA 
GGCATCGGCA CCTCAGTCAT CGTTGTCCGA GCCACCGACA GAGACACTGG GGACGGTGGC 
CTGGTGAACT ACCGCATCCT GTCGGGCGCA GAGGGCAAGT TTGAGATTGA CGAGAGCACA 
GGGCTCATCG TGACGGTTGA CTATCTGGAC TACGAGACCA AGACCAGCTA TCTGATGAAC 
GTGTCAGCCA CAGACGGTGC ACCCCCCTTC AACCAGGGCT TCTGCAGCGT CTACGTGACA 
CTTCTCAACG AGCTGGATGA GGCTGTTCAG TTCTCCAATG CCTCCTATGA GGCAGTCATC 
ATGGAGAATC TGGCTCTGGG GACCGAGATC GTGCGGGTGC AAGCCTATTC CATTGATAAC 
CTCAATCAAA TCACCTACCG CTTTGACGCC TATACCAGCG CCCAGGCCAA AGCCCTCTTC 
AAGATAGATG CCATCACGGG CGTGATCACA GTCAAAGGCT TGGTCGACAG GGAGAAGGGC 
GACTTCTACA CATTGACGGT CGTGGCAGAT GATGGTGGCC CCAAGGTGGA CTCTACTGTG 
AAGGTCTACG TCACTGTTCT GGATGAAAAT GATAACAGCC CACGCTTTGA CTTCACCTCT 
GATTCGGCCA TCAGTGTGCC TGAGGACTGC CCTGTAGGCC AACGAGTAGC CACTGTCAAG 
GCCCGGGACC CTGATGCTGG CAGCAACGGT CAGGTGGTCT TCTCCCTGGC CTCCGGTAAC 
ATTGCTGGGG CCTTTGAGAT TATCACCAGC AATGACTCCA TTGGTGAAGT GTTTGTGGCT 
AAGCCCCTGG ACAGGGAGGA ACTGGACCAC TACATCCTCA AGATTGTAGC TTCTGACCGT 
GGCACTCCTC CACGGAAGAA AGACCACATC TTACAGGTGA CCATTCTGGA TGTCAATGAC 
AACCCTCCAG TGATTGAGAG CCCCTTTGGG TACAACGTCA GTGTGAATGA GAATGTGGGT 
GGAGGCACCT CAGTAGTCCA GGTGAGAGCC ACCGACCGTG ACATCGGGAT CAACAGCGTC 
CTGTCCTATT ATATCACGGA GGGCAATGAG GACATGACTT TCCGTATGGA CCGCATCAGC 
GGTGAGATTG CTACACGGCC TGCTCCACCC GACCGTGAGC GCCAGAACTT CTACCACCTG 
GTGGTCACTG TGGAAGACGA GGGCACCCCC ACACTATCGG CTACCACCCA TGTGTACGTG 
ACTATCGTGG ACGAGAATGA CAATGCTCCT GTGTTCCAGC AGCCACATTA TGAGGTGGTG 
CTGGACGAGG GCCCGGACAC AGTCAACACC AGCCTCATCA CCGTCCAGGC GCTGGACCTG 
GATGAGGGCC CGAATGGCAC TGTTACCTAT GCCATTGTGG CAGGCAATAT CATCAATACC 
TTCCGAATCA ACAGGCGCAC GGGTGTCATT ACTGCTGCCA AGGAGCTAGA CTATGAGATC 
AGTCATGGCC GCTATACCCT GATTGTCACT GCCACAGACC AGTGTCCCAT CTTGTCCCAC 
CGCCTCACCT CTACTACCAC AGTGCTCGTG AACGTGAATG ACATCAATGA CAATGTGCCC 
ACTTTCCCTC GGGACTATGA AGGACCATTC GATGTCACTG AGGGCCAACC AGGGCCCAGA 
GTGTGGACAT TCCTGGCCCA TGACCGGGAC TCCGGTCCCA ATGGGCAGGT GGAGTACAGT 
GTTGTGGATG GAGACCCACT GGGGGAGTTT GTGATCTCTC CTGTGGAGGG TGTGCTGAGG 
GTCCGGAAGG ATGTAGAACT GGATCGGGAG ACCATCGCCT TCTACAATCT GACCATCTGT 
GCCCGAGACA GGGGGGTGCC GCCACTCAGC TCCACGATGC TGGTGGGAAT CCGAGTGCTG 
GACATCAATG ACAATGACCC GGTGCTGTTG AATCTTCCCA TGAACATCAC CATCAGTGAG 
AACAGCCCGG TCTCCAGCTT CGTCGCCCAC GTCCTGGCCA GCGACGCTGA CAGTGGCTGC 
AATGCCCTGC TCACCTTCAA CATCACCGCT GGCAACCGGG AGCGGGCCTT CTTCATCAAT 
GCCACGACAG GGATCGTCAC TGTCAACCGG CCCCTGGACC GAGAGCGCAT CCCAGAATAC 
AGGCTGACCG TTTCTGTAAA GGACAACCCA GAGAACCCAC GCATAGCCAG GAAGGATTTT 
GACTTACTGC TGGTCTCTCT GGCTGATGAA AATGACAACC ACCCCCTCTT CACTGAGGGC 
ACGTACCAGG CCGAGGTGAT GGAGAACTCT CCTGCTGGGA CACCTCTCAC CGTGCTCAAT 
GGACCTATCC TGGCCCTGGA TGCTGATGAA GATGTGTACG CTGTAGTCAC GTATCAACTC 
CTGGGCACTC ACAGCGACCT GTTTGTTATT GACAATAGCA CGGGCGTGGT GACTGTGAGG 
TCCGGGGTCA TCATCGACCG GGAGGCCTTC TCACCCCCAT TCCTGGAGTT GCTGCTGTTG 
GCTGAGGACG TGGGACAACT CAATGGCACG GCCTACCTGT TCATCACTAT CCTAGATGAC 
AATGACAACT GGCCCACCTT CAGTCCTCCT GCTTACACTG TCCACCTGCT GGAGAACTGC 
CCACCAGGAT TCTCAGTCCT TCAGATCACA GCCACAGATG AGGACAGCGG CCTCAATGGG 
GAGCTGGTCT ACCGAATAGA AGCCGGGGCT CAGGACCGCT TCCTCATCCA TCCAGTCACA 
GGAGTCATCC GTGTTGGCAA TGCCACCATT GACAGAGAAG AGCAGGAATC CTACAGGCTG 
ACGGTGGTGG CCACCGACCG GGGCACTGTT CCCTTGTCGG GCACAGCCAC CGTCACCATC 
CTGATCGATG ACATCAATGA CTCCCGCCCT GAGTTCCTCA ACCCTATCCA GACAGTGAGC 
GTGCTGGAAT CCACAGAGCC AGGCACTGTC ATTGCTAACG TCACTGCCAT CGACCTCGAC 
CTCAACCCCA AACTGGAGTA TCACATCCTT AGCATCGTGG CCAAGGACGA CACTGACCGC 
CTGGTGCCTG ACCAGGAAGA TGCCTTTGCT GTGAATATCA ATACAGGGTC CGTGATAGTG 
AAGTCCCCTC TGAACCGCGA GCTGGTTGCT ACCTATGAGG TCACGCTCTC AGTAATCGAC 
AATGCCAGCG ACCTCCCAGA GCGTTCTGTC AGTGTGCCAA ACGCCAAGCT CACGGTCAAC 
ATCCTGGATG TCAATGACAA TACACCGCAG TTCAAGCCCT TTGGAATCAC CTACTACACA 
GAGCGGGTCC TGGAGGGGGC CACCCCAGGC ACAACGCTCA TTGCTGTGGC CGCCGTTGAT 
CCCGACAAGG GCCTTAACGG GCTGATCACC TACACCCTGC TAGACCTCAT ACCCCCAGGC 
TATGTCCAGC TCGAAGACTC TTCAGCAGGG AAGGTCATCG CCAACCGTAC GGTGGACTAC 
GAGGAGGTTC ACTGGCTTAA CTTCACCGTG AGGGCCTCAG ACAATGGGTC CCCACCCCGG 
GCAGCTGAGA TCCCTGTCTA CCTGGAAATT GTAGACATTA ATGACAACAA CCCCATCTTT 
GATCAGCTCT CCTACCAGGA GGCTGTTTTT GAGGATGTAG CTGTGGGCAC GGTCATCCTG 
AGGGTTACAG CTACGGATGC TGACTCAGGC AACTTTGCTC TCATCGAGTA CAGCCTGGTG 
GATGGAGAGG GCAAATTTGC CATCAACCCC AACACTGGTG ACATCTATGT GCTGTCCTCT 
CTGGACCGAG AGAAGAAGGA CCACTACATC CTAACTGCTT TGGCCAAAGA CAACCCTGGC 
GATGTGGCCA GTAACCGTCG CGAGAACTCG GTGCAGGTGG TGATCCGAGT ACTTGATGTC 
AATGACTGTC GGCCTCAGTT CTCCAAGCCA CAGTTCAGCA CAAGTGTGTA CGAGAATGAG 
CCAGCAGGTA CTTCAGTCAT CACCATGCTG GCCACTGACC AGGACGAGGG CTCTAATGGC 
CAGCTGACCT ACTCTCTTGA GGGTCCCGGA ATGGAGGCTT TCTCTGTGGA CATGGACTCG 
GGCCTGGTGA CCACGCAGCG GCCACTACAG TCCTATGAGA GGTTCAACCT GACCGTAGTG 
GCTACAGATG GTGGGGAGCC CCCACTCTGG GGCACCACAA TGCTCCTAGT GGAAGTCATC 
GATGTCAATG ACAACCGCCC CGTCTTCGTG CGCCCACCCA ATGGCACCAT TCTGCACATC 
AAAGAGGAGA TCCCGCTACG TTCCAATGTG TATGAAGTCT ATGCTACAGA CAAGGATGAA 
GGCCTCAACG GGGCAGTACG CTACAGCTTC CTGAAGTCAA CAGGCAACCG TGACTGGGAG 
TACTTCACCA TCGACCCAAT TAGTGGCCTC ATCCAGACAG CGCAGCGCCT GGACCGTGAG 
AAGCAGGCAG TGTACAGTCT CATCTTGGTG GCCAGCGACC TGGGCCAGCC AGTGCCATAC 
GAGACGATGC AGCCATTGCA GGTGGCCCTG GAGGACATCG ATGACAATGA GCCCCTCTTT 
GTGAGGCCTC CTAAGGGAAG CCCTCAGTAC CAACTGCTAA CAGTGCCTGA ACACTCCCCC 
CGTGGCACCC TTGTGGGCAA CGTGACAGGC GCGGTGGACG CAGATGAAGG TCCCAATGCC 
ATTGTGTACT ACTTCATTGC AGCTGGTAAC GAGGACAAGA ATTTCCACCT ACAACCTGAC 
GGACGCCTGC TAGTGCTTAG AGACCTGGAT CGGGAGACGG AAGCCATCTT CTCCTTCATT 
GTCAAGGCGT CCAGCAATCG CAGTTGGACC CCTCCCCGAG GACCCTCCCC AGCCCTCGAT 
CTGCTGACCG ATCTCACCCT GCAGGAGGTG CGCGTTGTGC TGGAGGACAT CAATGACCAA 
CCGCCACGCT TCACCAAGGC TGAGTATACC GCAGGAGTGG CCACCGACGC CAAGGTAGGC 
TCGGAGTTGA TCCAGGTGCT GGCCCTGGAT GCAGACATTG GCAACAACAG CCTGGTCTTC 
TATGGCATTC TGGCTATCCA CTACTTCCGG GCCCTGGCCA ATGACTCCGA GGATGTGGGT 
CAGGTCTTCA CCATGGGGAG TGTGGACGGC ATCCTGCGTA CCTTTGACCT CTTCATGGCC 
TACAGCCCTG GCTACTTTGT GGTAGACATC GTGGCCCGAG ACCTGGCCGG TCACAACGAT 
ACAGCCATCA TTGGCATCTA CATCCTGAGG GATGACCAGC GCGTTAAGAT AGTCATCAAC 
GAGATCCCAG ACCGTGTGCG TGGCTTTGAG GAGGAGTTCA TTCGCCTGCT GTCCAACATC 
ACAGGCGCCA TCGTCAACAC TGATGACGTG CAGTTCCATG TGGATATGAA AGGAAGAGTG 
AATTTTGCAC AGACAGAGCT GCTCATCCAC GTGGTCAACC GCGACACGAA CCGCATCCTG 
GATGTGGACA GGGTCATCCA GATGATTGAT GAGAACAAGG AACAACTTCG AAACCTCTTC 
CGGAACTACA ATGTACTGGA CGTGCAGCCT GCCATCTCTG TCCAGCTGCC AGACGACATG 
TCTGCCCTGC AGATGGCCAT CATTGTCCTG GCCATCCTTC TCTTCTTGGC TGCCATGCTC 
TTTGTCCTCA TGAACTGGTA CTACAGGACC ATACACAAGA GAAAGCTAAA GGCCATTGTG 
GCTGGTTCTG CTGGGAACCG TGGCTTCATT GACATCATGG ACATGCCCAA TACCAACAAA 
TACTCCTTCG ATGGAGCCAA CCCTGTGTGG CTGGACCCCT TCTGCCGGAA CCTGGAGCTG 
GCTGCACAGG CTGAACACGA GGATGACCTC CCTGAGAACC TGAGTGAGAT CGCAGACCTG 
TGGAACAGCC CCACCCGCAC CCATGGAACT TTTGGACGTG AGCCCGCGGC AGTCAAACCT 
GAAGATGACA GATACCTGCG GGCAGCCATC CAGGAGTATG ACAACATAGC CAAGCTGGGT 
CAGATCATTC GAGAAGGACC TATTAAGCTG ATCCACACTG ACCTGGAGGA GGAGCCTGGC 
GACCACAGCC CAGGCCAGGG CAGCCTCCGT TTCCGACACA AGCCACCCAC GGAACTCAAG 
GGGCCAGATG GAATCCACAT AGTTCACGGT AGCACGGGCA CACTGCTGGC CACTGATCTC 
AACAGCTTGC CTGAGGACGA CCAGAAGGGG CTAGACCGCT CACTGGAGAC TCTGACAGCC 
TCTGAAGCCA CTGCCTTTGA ACGCAATGCC CGCACCGAGT CGGCCAAGTC CACCCCTCTG 
CATAAGCTTC GAGACGTCAT CATGGAGAGC CCCCTGGAAA TCACGGAACT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.
Proceedings of the National Academy of Sciences of the United States of America111(25)9307-12(2014 Jun)
Kamiya K,Michel V,Giraudet F,Riederer B,Foucher I,Papal S,Perfettini I,Le Gal S,Verpy E,Xia W,Seidler U,Georgescu MM,Avan P,El-Amraoui A,Petit C

Cyclic nucleotide-gated channel ?-3 (CNGA3) interacts with stereocilia tip-link cadherin 23 + exon 68 or alternatively with myosin VIIa, two proteins required for hair cell mechanotransduction.
The Journal of biological chemistry288(10)7215-29(2013 Mar)
Selvakumar D,Drescher MJ,Drescher DG

TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells.
Cell151(6)1283-95(2012 Dec)
Xiong W,Grillet N,Elledge HM,Wagner TF,Zhao B,Johnson KR,Kazmierczak P,M?ller U

Association of cadherin23 single nucleotide polymorphism with age-related hearing impairment in Han Chinese.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery147(3)531-4(2012 Sep)
Hwang JH,Liu KS,Wu CC,Liu TC

Sensing sound: molecules that orchestrate mechanotransduction by hair cells.
Trends in neurosciences35(4)220-9(2012 Apr)
Kazmierczak P,M?ller U

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Cdh23 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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